-
1
-
-
3142688368
-
Make WARTS, not cancer!
-
Edwards KM, Munger K. Make WARTS, not cancer! Oncogene 2004;23:5263-5.
-
(2004)
Oncogene
, vol.23
, pp. 5263-5265
-
-
Edwards, K.M.1
Munger, K.2
-
3
-
-
0037084163
-
Aurora-A overexpression reveals tetraploidization as a major route to centrosome amplification in p53-/- cells
-
Meraldi P, Honda R, Nigg EA. Aurora-A overexpression reveals tetraploidization as a major route to centrosome amplification in p53-/- cells. EMBO J 2002;21:483-92.
-
(2002)
EMBO J
, vol.21
, pp. 483-492
-
-
Meraldi, P.1
Honda, R.2
Nigg, E.A.3
-
4
-
-
0030013170
-
17p (p53) allelic losses, 4N (G2/tetraploid) populations, and progression to aneuploidy in Barrett's esophagus
-
Galipeau PC, Cowan DS, Sanchez CA, et al. 17p (p53) allelic losses, 4N (G2/tetraploid) populations, and progression to aneuploidy in Barrett's esophagus. Proc Natl Acad Sci U S A 1996;93:7081-4.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 7081-7084
-
-
Galipeau, P.C.1
Cowan, D.S.2
Sanchez, C.A.3
-
5
-
-
31644436369
-
Tetraploidy and chromosomal instability are early events during cervical carcinogenesis
-
Olaharski AJ, Sotelo R, Solorza-Luna G, et al. Tetraploidy and chromosomal instability are early events during cervical carcinogenesis. Carcinogenesis 2006;27:337-43.
-
(2006)
Carcinogenesis
, vol.27
, pp. 337-343
-
-
Olaharski, A.J.1
Sotelo, R.2
Solorza-Luna, G.3
-
6
-
-
27144507868
-
Cytokinesis failure generating tetraploids promotes tumorigenesis in p53-null cells
-
Fujiwara T, Bandi M, Nitta M, Ivanova EV, Bronson RT, Pellman D. Cytokinesis failure generating tetraploids promotes tumorigenesis in p53-null cells. Nature 2005; 437:1043-7.
-
(2005)
Nature
, vol.437
, pp. 1043-1047
-
-
Fujiwara, T.1
Bandi, M.2
Nitta, M.3
Ivanova, E.V.4
Bronson, R.T.5
Pellman, D.6
-
7
-
-
0031931414
-
Characterization of the p53-dependent postmitotic checkpoint following spindle disruption
-
Lanni JS, Jacks T. Characterization of the p53-dependent postmitotic checkpoint following spindle disruption. Mol Cell Biol 1998;18:1055-64.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 1055-1064
-
-
Lanni, J.S.1
Jacks, T.2
-
9
-
-
0347762556
-
From polyploidy to aneuploidy, genome instability and cancer
-
Storchova Z, Pellman D. From polyploidy to aneuploidy, genome instability and cancer. Nat Rev Mol Cell Biol 2004;5:45-54.
-
(2004)
Nat Rev Mol Cell Biol
, vol.5
, pp. 45-54
-
-
Storchova, Z.1
Pellman, D.2
-
10
-
-
0037162455
-
Multiple centrosomes arise from tetraploidy checkpoint failure and mitotic centrosome clusters in p53 and RB pocket protein-compromised cells
-
Borel F, Lohez OD, Lacroix FB, Margolis RL. Multiple centrosomes arise from tetraploidy checkpoint failure and mitotic centrosome clusters in p53 and RB pocket protein-compromised cells. Proc Natl Acad Sci U S A 2002;99:9819-24.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 9819-9824
-
-
Borel, F.1
Lohez, O.D.2
Lacroix, F.B.3
Margolis, R.L.4
-
11
-
-
0030929838
-
DNA rereplication in the presence of mitotic spindle inhibitors in human and mouse fibroblasts lacking either p53 or pRb function
-
Di Leonardo A, Khan SH, Linke SP, Greco V, Seidita G, Wahl GM. DNA rereplication in the presence of mitotic spindle inhibitors in human and mouse fibroblasts lacking either p53 or pRb function. Cancer Res 1997;57: 1013-9.
-
(1997)
Cancer Res
, vol.57
, pp. 1013-1019
-
-
Di Leonardo, A.1
Khan, S.H.2
Linke, S.P.3
Greco, V.4
Seidita, G.5
Wahl, G.M.6
-
13
-
-
0032952584
-
p21(Waf1/Cip1) inhibition of cyclin E/Cdk2 activity prevents endoreduplication after mitotic spindle disruption
-
Stewart ZA, Leach SD, Pietenpol JA. p21(Waf1/Cip1) inhibition of cyclin E/Cdk2 activity prevents endoreduplication after mitotic spindle disruption. Mol Cell Biol 1999;19:205-15.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 205-215
-
-
Stewart, Z.A.1
Leach, S.D.2
Pietenpol, J.A.3
-
14
-
-
2942679807
-
Cell cycle progression after cleavage failure: Mammalian somatic cells do not possess a tetraploidy checkpoint
-
Uetake Y, Sluder G. Cell cycle progression after cleavage failure: mammalian somatic cells do not possess a "tetraploidy checkpoint." J Cell Biol 2004;165: 609-15.
-
(2004)
J Cell Biol
, vol.165
, pp. 609-615
-
-
Uetake, Y.1
Sluder, G.2
-
15
-
-
25444533618
-
Mammalian cells lack checkpoints for tetraploidy, aberrant centrosome number, and cytokinesis failure
-
Wong C, Stearns T. Mammalian cells lack checkpoints for tetraploidy, aberrant centrosome number, and cytokinesis failure. BMC Cell Biol 2005;6:6.
-
(2005)
BMC Cell Biol
, vol.6
, pp. 6
-
-
Wong, C.1
Stearns, T.2
-
16
-
-
22244459880
-
Induction of apoptosis by an inhibitor of the mitotic kinesin KSP requires both activation of the spindle assembly checkpoint and mitotic slippage
-
Tao W, South VJ, Zhang Y, Davide JP, Farrell L, Kohl NE. Sepp-Lorenzino L, Lobell RB, Induction of apoptosis by an inhibitor of the mitotic kinesin KSP requires both activation of the spindle assembly checkpoint and mitotic slippage. Cancer Cell 2005;8:49-59.
-
(2005)
Cancer Cell
, vol.8
, pp. 49-59
-
-
Tao, W.1
South, V.J.2
Zhang, Y.3
Davide, J.P.4
Farrell, L.5
Kohl, N.E.6
Sepp-Lorenzino, L.7
Lobell, R.B.8
-
17
-
-
33745756364
-
Apoptosis regulation in tetraploid cancer cells
-
Castedo M, Coquelle A, Vivet S, et al. Apoptosis regulation in tetraploid cancer cells. EMBO J 2006;25: 2584-95.
-
(2006)
EMBO J
, vol.25
, pp. 2584-2595
-
-
Castedo, M.1
Coquelle, A.2
Vivet, S.3
-
18
-
-
9144242386
-
Dual roles of human BubR1, a mitotic checkpoint kinase, in the monitoring of chromosomal instability
-
Shin HJ, Baek KH, Jeon AH, et al. Dual roles of human BubR1, a mitotic checkpoint kinase, in the monitoring of chromosomal instability. Cancer Cell 2003;4:483-97.
-
(2003)
Cancer Cell
, vol.4
, pp. 483-497
-
-
Shin, H.J.1
Baek, K.H.2
Jeon, A.H.3
-
19
-
-
0029658664
-
Expression of Bcl-xL and loss of p53 can cooperate to overcome a cell cycle checkpoint induced by mitotic spindle damage
-
Minn AJ, Boise LH, Thompson CB. Expression of Bcl-xL and loss of p53 can cooperate to overcome a cell cycle checkpoint induced by mitotic spindle damage. Genes Dev 1996;10:2621-31.
-
(1996)
Genes Dev
, vol.10
, pp. 2621-2631
-
-
Minn, A.J.1
Boise, L.H.2
Thompson, C.B.3
-
20
-
-
0036559896
-
Papillomaviruses and cancer: From basic studies to clinical application
-
zur Hausen H. Papillomaviruses and cancer: from basic studies to clinical application. Nat Rev Cancer 2002;2:342-50.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 342-350
-
-
zur Hausen, H.1
-
21
-
-
0033587681
-
Human papillomavirus type 31 oncoproteins E6 and E7 are required for the maintenance of episomes during the viral life cycle in normal human keratinocytes
-
Thomas JT, Hubert WG, Ruesch MN, Laimins LA. Human papillomavirus type 31 oncoproteins E6 and E7 are required for the maintenance of episomes during the viral life cycle in normal human keratinocytes. Proc Natl Acad Sci U S A 1999;96:8449-54.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 8449-8454
-
-
Thomas, J.T.1
Hubert, W.G.2
Ruesch, M.N.3
Laimins, L.A.4
-
22
-
-
0027358723
-
The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53
-
Scheffner M, Huibregtse JM, Vierstra RD, Howley PM. The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53. Cell 1993;75:495-505.
-
(1993)
Cell
, vol.75
, pp. 495-505
-
-
Scheffner, M.1
Huibregtse, J.M.2
Vierstra, R.D.3
Howley, P.M.4
-
23
-
-
3142673498
-
Regulation of cell cycle progression and apoptosis by the papillomavirus E6 oncogene
-
Fan X, Chen JJ. Regulation of cell cycle progression and apoptosis by the papillomavirus E6 oncogene. Crit Rev Eukaryot Gene Expr 2004;14:183-202.
-
(2004)
Crit Rev Eukaryot Gene Expr
, vol.14
, pp. 183-202
-
-
Fan, X.1
Chen, J.J.2
-
24
-
-
0031577693
-
The human papillomavirus-16 E6 oncoprotein decreases the vigilance of mitotic checkpoints
-
Thompson DA, Belinsky G, Chang TH, Jones DL, Schlegel R, Munger K. The human papillomavirus-16 E6 oncoprotein decreases the vigilance of mitotic checkpoints. Oncogene 1997;15:3025-35.
-
(1997)
Oncogene
, vol.15
, pp. 3025-3035
-
-
Thompson, D.A.1
Belinsky, G.2
Chang, T.H.3
Jones, D.L.4
Schlegel, R.5
Munger, K.6
-
25
-
-
0031930282
-
Human papillomavirus oncoproteins E6 and E7 independently abrogate the mitotic spindle checkpoint
-
Thomas JT, Laimins LA. Human papillomavirus oncoproteins E6 and E7 independently abrogate the mitotic spindle checkpoint. J Virol 1998;72:1131-7.
-
(1998)
J Virol
, vol.72
, pp. 1131-1137
-
-
Thomas, J.T.1
Laimins, L.A.2
-
27
-
-
0025678371
-
Cell line-specific differences in the control of cell cycle progression in the absence of mitosis
-
Rung AL, Sherwood SW, Schimke RT. Cell line-specific differences in the control of cell cycle progression in the absence of mitosis. Proc Natl Acad Sci U S A 1990;87:9553-7.
-
(1990)
Proc Natl Acad Sci U S A
, vol.87
, pp. 9553-9557
-
-
Rung, A.L.1
Sherwood, S.W.2
Schimke, R.T.3
-
28
-
-
0026609366
-
The E6 and E7 genes of human papillomavirus type 6 have weak immortalizing activity in human epithelial cells
-
Halbert CL, Demers GW, Galloway DA. The E6 and E7 genes of human papillomavirus type 6 have weak immortalizing activity in human epithelial cells. J Virol 1992;66:2125-34.
-
(1992)
J Virol
, vol.66
, pp. 2125-2134
-
-
Halbert, C.L.1
Demers, G.W.2
Galloway, D.A.3
-
29
-
-
0034099718
-
Normal growth and differentiation in a spontaneously immortalized near-diploid human keratinocyte cell line, NIKS
-
Allen-Hoffmann BL, Schlosser SJ, Ivarie CA, Sattler CA, Meisner LF, O'Connor SL. Normal growth and differentiation in a spontaneously immortalized near-diploid human keratinocyte cell line, NIKS. J Invest Dermatol 2000;114:444-55.
-
(2000)
J Invest Dermatol
, vol.114
, pp. 444-455
-
-
Allen-Hoffmann, B.L.1
Schlosser, S.J.2
Ivarie, C.A.3
Sattler, C.A.4
Meisner, L.F.5
O'Connor, S.L.6
-
30
-
-
0033947269
-
The human papillomavirus type 16 E7 oncogene is required for the productive stage of the viral life cycle
-
Flores ER, Allen-Hoffmann BL, Lee D, Lambert PF. The human papillomavirus type 16 E7 oncogene is required for the productive stage of the viral life cycle. J Virol 2000;74:6622-31.
-
(2000)
J Virol
, vol.74
, pp. 6622-6631
-
-
Flores, E.R.1
Allen-Hoffmann, B.L.2
Lee, D.3
Lambert, P.F.4
-
31
-
-
0024512996
-
Distinctive traits of normal and tumor-derived human mammary epithelial cells expressed in a medium that supports long-term growth of both cell types
-
Band V, Sager R. Distinctive traits of normal and tumor-derived human mammary epithelial cells expressed in a medium that supports long-term growth of both cell types. Proc Natl Acad Sci U S A 1989;86: 1249-53.
-
(1989)
Proc Natl Acad Sci U S A
, vol.86
, pp. 1249-1253
-
-
Band, V.1
Sager, R.2
-
32
-
-
0031438309
-
Destabilization of the RB tumor suppressor protein and stabilization of p53 contribute to HPV type 16 E7-induced apoptosis
-
Jones DL, Thompson DA, Munger K. Destabilization of the RB tumor suppressor protein and stabilization of p53 contribute to HPV type 16 E7-induced apoptosis. Virology 1997;239:97-107.
-
(1997)
Virology
, vol.239
, pp. 97-107
-
-
Jones, D.L.1
Thompson, D.A.2
Munger, K.3
-
33
-
-
10044279571
-
Human papillomavirus type 16 e6 promotes retinoblastoma protein phosphorylation and cell cycle progression
-
Malanchi I, Accardi R, Diehl F, et al. Human papillomavirus type 16 e6 promotes retinoblastoma protein phosphorylation and cell cycle progression. J Virol 2004;78:13769-78.
-
(2004)
J Virol
, vol.78
, pp. 13769-13778
-
-
Malanchi, I.1
Accardi, R.2
Diehl, F.3
-
35
-
-
1242316161
-
Acquisition of high-level chromosomal instability is associated with integration of human papillomavirus type 16 in cervical keratinocytes
-
Pett MR, Alazawi WO, Roberts I, et al. Acquisition of high-level chromosomal instability is associated with integration of human papillomavirus type 16 in cervical keratinocytes. Cancer Res 2004;64:1359-68.
-
(2004)
Cancer Res
, vol.64
, pp. 1359-1368
-
-
Pett, M.R.1
Alazawi, W.O.2
Roberts, I.3
-
36
-
-
12844274301
-
DNA damage-induced mitotic catastrophe is mediated by the Chk1-dependent mitotic exit DNA damage checkpoint
-
Huang X, Tran T, Zhang L, Hatcher R, Zhang P. DNA damage-induced mitotic catastrophe is mediated by the Chk1-dependent mitotic exit DNA damage checkpoint. Proc Natl Acad Sci U S A 2005;102:1065-70.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 1065-1070
-
-
Huang, X.1
Tran, T.2
Zhang, L.3
Hatcher, R.4
Zhang, P.5
-
37
-
-
0033619108
-
Establishment of the human papillomavirus type 16 (HPV-16) life cycle in an immortalized human foreskin keratinocyte cell line
-
Flores ER, Allen-Hoffmann BL, Lee D, Sattler CA, Lambert PF. Establishment of the human papillomavirus type 16 (HPV-16) life cycle in an immortalized human foreskin keratinocyte cell line. Virology 1999;262: 344-54.
-
(1999)
Virology
, vol.262
, pp. 344-354
-
-
Flores, E.R.1
Allen-Hoffmann, B.L.2
Lee, D.3
Sattler, C.A.4
Lambert, P.F.5
-
38
-
-
0033520367
-
Identification of a novel phosphorylation site on histone H3 coupled with mitotic chromosome condensation
-
Goto H, Tomono Y, Ajiro K, et al. Identification of a novel phosphorylation site on histone H3 coupled with mitotic chromosome condensation. J Biol Chem 1999; 274:25543-9.
-
(1999)
J Biol Chem
, vol.274
, pp. 25543-25549
-
-
Goto, H.1
Tomono, Y.2
Ajiro, K.3
-
39
-
-
0032563638
-
Entry into mitosis in vertebrate somatic cells is guarded by a chromosome damage checkpoint that reverses the cell cycle when triggered during early but not late prophase
-
Rieder CL, Cole RW. Entry into mitosis in vertebrate somatic cells is guarded by a chromosome damage checkpoint that reverses the cell cycle when triggered during early but not late prophase. J Cell Biol 1998;142: 1013-22.
-
(1998)
J Cell Biol
, vol.142
, pp. 1013-1022
-
-
Rieder, C.L.1
Cole, R.W.2
-
40
-
-
0032816001
-
Androphy EJ, Multiple functions of human papillomavirus type 16 E6 contribute to the immortalization of mammary epithelial cells
-
Liu Y, Chen JJ, Gao Q, et al. Androphy EJ, Multiple functions of human papillomavirus type 16 E6 contribute to the immortalization of mammary epithelial cells. J Virol 1999;73:7297-307.
-
(1999)
J Virol
, vol.73
, pp. 7297-7307
-
-
Liu, Y.1
Chen, J.J.2
Gao, Q.3
-
41
-
-
0036318569
-
Human papillomavirus oncoprotein E6 inactivates the transcriptional coactivator human ADA3
-
Kumar A, Zhao Y, Meng G, et al. Human papillomavirus oncoprotein E6 inactivates the transcriptional coactivator human ADA3. Mol Cell Biol 2002;22:5801-12.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 5801-5812
-
-
Kumar, A.1
Zhao, Y.2
Meng, G.3
-
43
-
-
12344295621
-
E6 oncoprotein represses p53-dependent gene activation via inhibition of protein acetylation independently of inducing p53 degradation
-
Thomas MC. Chiang CM. E6 oncoprotein represses p53-dependent gene activation via inhibition of protein acetylation independently of inducing p53 degradation. Mol Cell 2005;17:251-64.
-
(2005)
Mol Cell
, vol.17
, pp. 251-264
-
-
Thomas, M.C.1
Chiang, C.M.2
-
44
-
-
0028907552
-
Functional p53 protein in human papillomavirus-positive cancer cells
-
Butz K, Shahabeddin L, Geisen C, Spitkovsky D, Ullmann A, Hoppe-Seyler F. Functional p53 protein in human papillomavirus-positive cancer cells. Oncogene 1995;10:927-36.
-
(1995)
Oncogene
, vol.10
, pp. 927-936
-
-
Butz, K.1
Shahabeddin, L.2
Geisen, C.3
Spitkovsky, D.4
Ullmann, A.5
Hoppe-Seyler, F.6
-
45
-
-
33646124023
-
Induction of tetraploidy through loss of p53 and upregulation of Plk1 by human papillomavirus type-16 E6
-
Incassati A, Patel D, McCance DJ. Induction of tetraploidy through loss of p53 and upregulation of Plk1 by human papillomavirus type-16 E6. Oncogene 2006;25:2444-51.
-
(2006)
Oncogene
, vol.25
, pp. 2444-2451
-
-
Incassati, A.1
Patel, D.2
McCance, D.J.3
-
46
-
-
0036897282
-
The human papillomavirus type 16 E6 and E7 oncoproteins independently induce numerical and structural chromosome instability
-
Duensing S, Munger K. The human papillomavirus type 16 E6 and E7 oncoproteins independently induce numerical and structural chromosome instability. Cancer Res 2002;62:7075-82.
-
(2002)
Cancer Res
, vol.62
, pp. 7075-7082
-
-
Duensing, S.1
Munger, K.2
-
47
-
-
32244439530
-
Rb inactivation leads to E2F1-mediated DNA double-strand break accumulation
-
Pickering MT, Kowalik TF. Rb inactivation leads to E2F1-mediated DNA double-strand break accumulation. Oncogene 2006;25:746-55.
-
(2006)
Oncogene
, vol.25
, pp. 746-755
-
-
Pickering, M.T.1
Kowalik, T.F.2
|