-
1
-
-
0742269867
-
New insights into 2-methoxyestradiol, a promising antiangiogenic and antitumor agent
-
Mooberry S.L. New insights into 2-methoxyestradiol, a promising antiangiogenic and antitumor agent. Curr. Opin. Oncol. 15 (2003) 425-430
-
(2003)
Curr. Opin. Oncol.
, vol.15
, pp. 425-430
-
-
Mooberry, S.L.1
-
2
-
-
27144486110
-
β-Tubulin mutations are associated with resistance to 2-methoxyestradiol in MDA-MB-435 cancer cells
-
Gokmen-Polar Y., Escuin D., Walls C.D., Soule S.E., Wang Y., Sanders K.L., Lavallee T.M., Wang M., Guenther B.D., Giannakakou P., and Sledge Jr. G.W. β-Tubulin mutations are associated with resistance to 2-methoxyestradiol in MDA-MB-435 cancer cells. Cancer Res. 65 (2005) 9406-9414
-
(2005)
Cancer Res.
, vol.65
, pp. 9406-9414
-
-
Gokmen-Polar, Y.1
Escuin, D.2
Walls, C.D.3
Soule, S.E.4
Wang, Y.5
Sanders, K.L.6
Lavallee, T.M.7
Wang, M.8
Guenther, B.D.9
Giannakakou, P.10
Sledge Jr., G.W.11
-
3
-
-
12544253612
-
Synergism between the anticancer actions of 2-methoxyestradiol and microtubule-disrupting agents in human breast cancer
-
Han G.Z., Liu Z.J., Shimoi K., and Zhu B.T. Synergism between the anticancer actions of 2-methoxyestradiol and microtubule-disrupting agents in human breast cancer. Cancer Res. 65 (2005) 387-393
-
(2005)
Cancer Res.
, vol.65
, pp. 387-393
-
-
Han, G.Z.1
Liu, Z.J.2
Shimoi, K.3
Zhu, B.T.4
-
4
-
-
11144239579
-
2-Methoxyestradiol inhibits hypoxia-inducible factor 1alpha, tumor growth, and angiogenesis and augments paclitaxel efficacy in head and neck squamous cell carcinoma
-
Ricker J.L., Chen Z., Yang X.P., Pribluda V.S., Swartz G.M., and Van Waes C. 2-Methoxyestradiol inhibits hypoxia-inducible factor 1alpha, tumor growth, and angiogenesis and augments paclitaxel efficacy in head and neck squamous cell carcinoma. Clin. Cancer Res. 10 (2004) 8665-8673
-
(2004)
Clin. Cancer Res.
, vol.10
, pp. 8665-8673
-
-
Ricker, J.L.1
Chen, Z.2
Yang, X.P.3
Pribluda, V.S.4
Swartz, G.M.5
Van Waes, C.6
-
5
-
-
0037211257
-
Urinary estrogen metabolites and breast cancer: differential pattern of risk found with pre- versus post-treatment collection
-
Fowke J.H., Qi D., Bradlow H.L., Shu X.O., Gao Y.T., Cheng J.R., Jin F., and Zheng W. Urinary estrogen metabolites and breast cancer: differential pattern of risk found with pre- versus post-treatment collection. Steroids 68 (2003) 65-72
-
(2003)
Steroids
, vol.68
, pp. 65-72
-
-
Fowke, J.H.1
Qi, D.2
Bradlow, H.L.3
Shu, X.O.4
Gao, Y.T.5
Cheng, J.R.6
Jin, F.7
Zheng, W.8
-
6
-
-
0000317180
-
Is 2-methoxyestradiol an endogenous estrogen metabolite that inhibits mammary carcinogenesis?
-
Zhu B.T., and Conney A.H. Is 2-methoxyestradiol an endogenous estrogen metabolite that inhibits mammary carcinogenesis?. Cancer Res. 58 (1998) 2269-2277
-
(1998)
Cancer Res.
, vol.58
, pp. 2269-2277
-
-
Zhu, B.T.1
Conney, A.H.2
-
7
-
-
0033998724
-
Genetic polymorphism of cytochrome P450-1B1 and risk of breast cancer
-
Zheng W., Xie D.W., Jin F., Cheng J.R., Dai Q., Wen W.Q., Shu X.O., and Gao Y.T. Genetic polymorphism of cytochrome P450-1B1 and risk of breast cancer. Cancer Epidemiol. Biomarkers Prev. 9 (2000) 147-150
-
(2000)
Cancer Epidemiol. Biomarkers Prev.
, vol.9
, pp. 147-150
-
-
Zheng, W.1
Xie, D.W.2
Jin, F.3
Cheng, J.R.4
Dai, Q.5
Wen, W.Q.6
Shu, X.O.7
Gao, Y.T.8
-
8
-
-
0029059604
-
4-Hydroxylation of estradiol by human uterine myometrium and myoma microsomes: implications for the mechanism of uterine tumorigenesis
-
Liehr J.G., Ricci M.J., Jefcoate C.R., Hannigan E.V., Hokanson J.A., and Zhu B.T. 4-Hydroxylation of estradiol by human uterine myometrium and myoma microsomes: implications for the mechanism of uterine tumorigenesis. Proc. Natl. Acad. Sci. USA 92 (1995) 9220-9224
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 9220-9224
-
-
Liehr, J.G.1
Ricci, M.J.2
Jefcoate, C.R.3
Hannigan, E.V.4
Hokanson, J.A.5
Zhu, B.T.6
-
9
-
-
0242662678
-
Estrogen and its metabolites are carcinogenic agents in human breast epithelial cells
-
Russo J., Hasan L.M., Balogh G., Guo S., and Russo I.H. Estrogen and its metabolites are carcinogenic agents in human breast epithelial cells. J. Steroid Biochem Mol. Biol. 87 (2003) 1-25
-
(2003)
J. Steroid Biochem Mol. Biol.
, vol.87
, pp. 1-25
-
-
Russo, J.1
Hasan, L.M.2
Balogh, G.3
Guo, S.4
Russo, I.H.5
-
11
-
-
25144452785
-
A phase II multicenter, randomized, double-blind, safety trial assessing the pharmacokinetics, pharmacodynamics, and efficacy of oral 2-methoxyestradiol capsules in hormone-refractory prostate cancer
-
Sweeney C., Liu G., Yiannoutsos C., Kolesar J., Horvath D., Staab M.J., et al. A phase II multicenter, randomized, double-blind, safety trial assessing the pharmacokinetics, pharmacodynamics, and efficacy of oral 2-methoxyestradiol capsules in hormone-refractory prostate cancer. Clin. Cancer Res. 11 (2005) 6625-6633
-
(2005)
Clin. Cancer Res.
, vol.11
, pp. 6625-6633
-
-
Sweeney, C.1
Liu, G.2
Yiannoutsos, C.3
Kolesar, J.4
Horvath, D.5
Staab, M.J.6
-
12
-
-
0037320432
-
2-Methoxyestradiol, a promising anticancer agent
-
Lakhani N.J., Sarkar M.A., Venitz J., and Figg W.D. 2-Methoxyestradiol, a promising anticancer agent. Pharmacotherapy 23 (2003) 165-712
-
(2003)
Pharmacotherapy
, vol.23
, pp. 165-712
-
-
Lakhani, N.J.1
Sarkar, M.A.2
Venitz, J.3
Figg, W.D.4
-
13
-
-
0028331925
-
2-Methoxyestradiol, an endogenous mammalian metabolite, inhibits tubulin polymerization by interacting at the colchicine site
-
D'Amato R.J., Lin C.M., Flynn E., Folkman J., and Hamel E. 2-Methoxyestradiol, an endogenous mammalian metabolite, inhibits tubulin polymerization by interacting at the colchicine site. Proc. Natl. Acad. Sci. USA 91 (1994) 3964-3968
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 3964-3968
-
-
D'Amato, R.J.1
Lin, C.M.2
Flynn, E.3
Folkman, J.4
Hamel, E.5
-
14
-
-
0028220858
-
The endogenous oestrogen metabolite 2-methoxyestradiol inhibits angiogenesis and suppresses tumor growth
-
Fotsis T., Zhang Y., Pepper M.S., Adlercreutz H., Montesanno R., Nawroth P.P., and Schwelgerer L. The endogenous oestrogen metabolite 2-methoxyestradiol inhibits angiogenesis and suppresses tumor growth. Nature 368 (1994) 237-239
-
(1994)
Nature
, vol.368
, pp. 237-239
-
-
Fotsis, T.1
Zhang, Y.2
Pepper, M.S.3
Adlercreutz, H.4
Montesanno, R.5
Nawroth, P.P.6
Schwelgerer, L.7
-
15
-
-
0036044045
-
Dual effect of 2-methoxyestradiol on cell cycle events in human osteosarcoma 143B cells
-
Golebiewska J., Rozwadowski P., Spodnik J.H., Knap N., Wakabayashi T., and Wozniak M. Dual effect of 2-methoxyestradiol on cell cycle events in human osteosarcoma 143B cells. Acta Biochim. Pol. 49 (2002) 59-65
-
(2002)
Acta Biochim. Pol.
, vol.49
, pp. 59-65
-
-
Golebiewska, J.1
Rozwadowski, P.2
Spodnik, J.H.3
Knap, N.4
Wakabayashi, T.5
Wozniak, M.6
-
16
-
-
33646239176
-
Physiological levels of 2-methoxyestradiol interfere with nongenomic signaling of 17β-Estradiol in human breast cancer cells
-
Vijayanathan V., Venkiteswaran S., Nair S.K., Verma A., Thomas T.J., Zhu B.T., and Thomas T. Physiological levels of 2-methoxyestradiol interfere with nongenomic signaling of 17β-Estradiol in human breast cancer cells. Clinical Cancer Res. 12 (2006) 2038-2048
-
(2006)
Clinical Cancer Res.
, vol.12
, pp. 2038-2048
-
-
Vijayanathan, V.1
Venkiteswaran, S.2
Nair, S.K.3
Verma, A.4
Thomas, T.J.5
Zhu, B.T.6
Thomas, T.7
-
17
-
-
0034699513
-
Superoxide dismutase as a target for the selective killing of cancer cells
-
Huang P., Feng L., Oldham E.A., Keating M.J., and Plunkett W. Superoxide dismutase as a target for the selective killing of cancer cells. Nature 407 (2000) 390-395
-
(2000)
Nature
, vol.407
, pp. 390-395
-
-
Huang, P.1
Feng, L.2
Oldham, E.A.3
Keating, M.J.4
Plunkett, W.5
-
18
-
-
2142761525
-
Concentration-dependent mitogenic and antiproliferative actions of 2-methoxyestradiol in estrogen receptor-positive human breast cancer cells
-
Liu Z.J., and Zhu B.T. Concentration-dependent mitogenic and antiproliferative actions of 2-methoxyestradiol in estrogen receptor-positive human breast cancer cells. J. Steroid Biochem. Mol. Biol. 88 (2004) 265-275
-
(2004)
J. Steroid Biochem. Mol. Biol.
, vol.88
, pp. 265-275
-
-
Liu, Z.J.1
Zhu, B.T.2
-
20
-
-
4944242891
-
Polyamines and cancer: old molecules, new understanding
-
Gerner E.W., and Meyskens Jr. F.L. Polyamines and cancer: old molecules, new understanding. Nat. Rev. Cancer 4 (2004) 781-792
-
(2004)
Nat. Rev. Cancer
, vol.4
, pp. 781-792
-
-
Gerner, E.W.1
Meyskens Jr., F.L.2
-
22
-
-
0028169362
-
Effect of 1,19-bis(ethylamino)-5,10,15-triazanonadecane on human tumor xenografts
-
Dolan M.E., Fleig M.J., Feuerstein B.G., Basu H.S., Luk G.D., Casero Jr. R.A., and J Marton L. Effect of 1,19-bis(ethylamino)-5,10,15-triazanonadecane on human tumor xenografts. Cancer Res. 54 (1994) 4698-4702
-
(1994)
Cancer Res.
, vol.54
, pp. 4698-4702
-
-
Dolan, M.E.1
Fleig, M.J.2
Feuerstein, B.G.3
Basu, H.S.4
Luk, G.D.5
Casero Jr., R.A.6
J Marton, L.7
-
23
-
-
0032766004
-
Prognostic value of ornithine decarboxylase and polyamines in human breast cancer: correlation with clinicopathologic parameters
-
Canizares F., Salinas J., de las Heras M., Diaz J., Tovar I., Martinez P., and Penafiel R. Prognostic value of ornithine decarboxylase and polyamines in human breast cancer: correlation with clinicopathologic parameters. Clin. Cancer Res. 5 (1999) 2035-2041
-
(1999)
Clin. Cancer Res.
, vol.5
, pp. 2035-2041
-
-
Canizares, F.1
Salinas, J.2
de las Heras, M.3
Diaz, J.4
Tovar, I.5
Martinez, P.6
Penafiel, R.7
-
24
-
-
0028265460
-
Estradiol control of ornithine decarboxylase mRNA, enzyme activity, and polyamine levels in MCF-7 breast cancer cells: therapeutic implications
-
Thomas T., and Thomas T.J. Estradiol control of ornithine decarboxylase mRNA, enzyme activity, and polyamine levels in MCF-7 breast cancer cells: therapeutic implications. Breast Cancer Res. Treat. 29 (1994) 101-189
-
(1994)
Breast Cancer Res. Treat.
, vol.29
, pp. 101-189
-
-
Thomas, T.1
Thomas, T.J.2
-
27
-
-
0346734280
-
11-diethylnorspermine (DENSpm) daily for five days every 21 days in patients with previously treated metastatic breast cancer
-
11-diethylnorspermine (DENSpm) daily for five days every 21 days in patients with previously treated metastatic breast cancer. Clin. Cancer Res. 9 (2003) 5922-5928
-
(2003)
Clin. Cancer Res.
, vol.9
, pp. 5922-5928
-
-
Wolff, A.C.1
K Armstrong, D.2
Fetting, J.H.3
Carducci, M.K.4
Riley, C.D.5
Bender, J.F.6
Casero Jr., R.A.7
Davidson, N.E.8
-
28
-
-
16844382968
-
Signaling intricacies take center stage in cancer cells
-
Kumar R., and Hung M.C. Signaling intricacies take center stage in cancer cells. Cancer Res. 65 (2005) 2511-2515
-
(2005)
Cancer Res.
, vol.65
, pp. 2511-2515
-
-
Kumar, R.1
Hung, M.C.2
-
30
-
-
28844433950
-
Akt is frequently activated in HER2/neu-positive breast cancers and associated with poor prognosis among hormone-treated patients
-
Tokunaga E., Kimura Y., Oki E., Ueda N., Futatsugi M., Mashino K., et al. Akt is frequently activated in HER2/neu-positive breast cancers and associated with poor prognosis among hormone-treated patients. Int. J. Cancer 118 (2005) 284-289
-
(2005)
Int. J. Cancer
, vol.118
, pp. 284-289
-
-
Tokunaga, E.1
Kimura, Y.2
Oki, E.3
Ueda, N.4
Futatsugi, M.5
Mashino, K.6
-
31
-
-
0038700565
-
Akt kinases in breast cancer and the results of adjuvant therapy
-
Stal O., Perez-Tenorio G., Akerberg L., Olsson B., Nordenskjold, Skoog L., and Rutqvist L.E. Akt kinases in breast cancer and the results of adjuvant therapy. Breast Cancer Res. 5 (2003) R37-R44
-
(2003)
Breast Cancer Res.
, vol.5
-
-
Stal, O.1
Perez-Tenorio, G.2
Akerberg, L.3
Olsson, B.4
Nordenskjold5
Skoog, L.6
Rutqvist, L.E.7
-
32
-
-
0036633164
-
Constitutive and inducible Akt activity promotes resistance to chemotherapy, trastuzumab, or tamoxifen in breast cancer cells
-
Clark A.S., West K., Streicher S., and Dennis P.A. Constitutive and inducible Akt activity promotes resistance to chemotherapy, trastuzumab, or tamoxifen in breast cancer cells. Mol. Cancer Ther. 1 (2002) 707-717
-
(2002)
Mol. Cancer Ther.
, vol.1
, pp. 707-717
-
-
Clark, A.S.1
West, K.2
Streicher, S.3
Dennis, P.A.4
-
33
-
-
0035971181
-
Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor α: a new model for anti-estrogen resistance
-
Campbell R.A., Bhat-Nakshatri P., Patel N.M., Constantinidou D.S., and Nakshatri H. Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor α: a new model for anti-estrogen resistance. J. Biol. Chem. 276 (2001) 9817-9824
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 9817-9824
-
-
Campbell, R.A.1
Bhat-Nakshatri, P.2
Patel, N.M.3
Constantinidou, D.S.4
Nakshatri, H.5
-
35
-
-
4644325161
-
Estrogen receptors as targets for drug development for breast cancer, osteoporosis and cardiovascular diseases
-
Thomas T., Gallo M.A., and Thomas T.J. Estrogen receptors as targets for drug development for breast cancer, osteoporosis and cardiovascular diseases. Curr. Cancer Drug Targets 4 (2004) 483-499
-
(2004)
Curr. Cancer Drug Targets
, vol.4
, pp. 483-499
-
-
Thomas, T.1
Gallo, M.A.2
Thomas, T.J.3
-
36
-
-
0034911153
-
Characterization of the NADPH-dependent metabolism of 17β-estradiol to multiple metabolites by human liver microsomes and selectively expressed human cytochrome P450 3A4 and 3A5
-
Lee A.J., Kosh J.W., Conney A.H., and Zhu B.T. Characterization of the NADPH-dependent metabolism of 17β-estradiol to multiple metabolites by human liver microsomes and selectively expressed human cytochrome P450 3A4 and 3A5. J. Pharmacol. Exp. Ther. 298 (2001) 420-432
-
(2001)
J. Pharmacol. Exp. Ther.
, vol.298
, pp. 420-432
-
-
Lee, A.J.1
Kosh, J.W.2
Conney, A.H.3
Zhu, B.T.4
-
37
-
-
33748794547
-
Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies
-
Chou T.C. Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies. Pharmacol. Rev. 58 (2006) 621-681
-
(2006)
Pharmacol. Rev.
, vol.58
, pp. 621-681
-
-
Chou, T.C.1
-
38
-
-
0021118703
-
Quantitiative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors
-
Chou T.C., and Talalay P. Quantitiative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors. Ad. Enzyme Regul. 22 (1984) 27-55
-
(1984)
Ad. Enzyme Regul.
, vol.22
, pp. 27-55
-
-
Chou, T.C.1
Talalay, P.2
-
39
-
-
34047204349
-
-
T.C. Chou, N. Martin, CompuSyn for Drug Combinations: PC Software and User's Guide. A computer program for quantitation of synergism and antagonism in drug combinations, and the determination of IC50 and ED50 and LD50 values. ComboSyn, Paramus, NJ, 2005.
-
-
-
-
40
-
-
0028153260
-
Computerized quantitation of synergism and antagonism of taxol, topotecan, and cisplatin against human teratocarcinoma cell growth: a rational approach to clinical protocol design
-
Chou T.C., Motzer R.J., Tong Y., and Bosl G.J. Computerized quantitation of synergism and antagonism of taxol, topotecan, and cisplatin against human teratocarcinoma cell growth: a rational approach to clinical protocol design. J. Natl Cancer Inst. 86 (1994) 1517-1524
-
(1994)
J. Natl Cancer Inst.
, vol.86
, pp. 1517-1524
-
-
Chou, T.C.1
Motzer, R.J.2
Tong, Y.3
Bosl, G.J.4
-
41
-
-
14544273363
-
Differential effects of 16α-hydroxyestrone and 2-methoxyestradiol on cyclin D1 involving the transcription factor ATF-2 in MCF-7 breast cancer cells
-
Lewis J.S., Thomas T.J., Pestell R.G., Albanese C., Gallo M.A., and Thomas T. Differential effects of 16α-hydroxyestrone and 2-methoxyestradiol on cyclin D1 involving the transcription factor ATF-2 in MCF-7 breast cancer cells. J. Mol. Endocrinol. 34 (2005) 91-105
-
(2005)
J. Mol. Endocrinol.
, vol.34
, pp. 91-105
-
-
Lewis, J.S.1
Thomas, T.J.2
Pestell, R.G.3
Albanese, C.4
Gallo, M.A.5
Thomas, T.6
-
42
-
-
33645222234
-
Modulation of cell-cycle regulatory signaling network by 2-methoxyestradiol in prostate cancer cells is mediated through multiple signal transduction pathways
-
Ray G., Dhar G., Van Veldhuizen P.J., Banerjee S., Saxena N.K., Sengupta K., and Banerjee S.K. Modulation of cell-cycle regulatory signaling network by 2-methoxyestradiol in prostate cancer cells is mediated through multiple signal transduction pathways. Biochemistry 45 (2006) 3703-3713
-
(2006)
Biochemistry
, vol.45
, pp. 3703-3713
-
-
Ray, G.1
Dhar, G.2
Van Veldhuizen, P.J.3
Banerjee, S.4
Saxena, N.K.5
Sengupta, K.6
Banerjee, S.K.7
-
43
-
-
23744499946
-
Progesterone inhibits the estrogen-induced phosphoinositide 3-kinase- > AKT- > GSK-3β- > cyclin D1- > pRB pathway to block uterine epithelial cell proliferation
-
Chen B., Pan H., Zhu L., Deng Y., and Pollard J.W. Progesterone inhibits the estrogen-induced phosphoinositide 3-kinase- > AKT- > GSK-3β- > cyclin D1- > pRB pathway to block uterine epithelial cell proliferation. Mol. Endocrinol. 19 (2005) 1978-1990
-
(2005)
Mol. Endocrinol.
, vol.19
, pp. 1978-1990
-
-
Chen, B.1
Pan, H.2
Zhu, L.3
Deng, Y.4
Pollard, J.W.5
-
44
-
-
3042843668
-
Estradiol abrogates apoptosis in breast cancer cells through inactivation of BAD: Ras-dependent nongenomic pathways requiring signaling through ERK and Akt
-
Fernando R.I., and Wimalasena J. Estradiol abrogates apoptosis in breast cancer cells through inactivation of BAD: Ras-dependent nongenomic pathways requiring signaling through ERK and Akt. Mol. Biol. Cell 15 (2004) 3266-3284
-
(2004)
Mol. Biol. Cell
, vol.15
, pp. 3266-3284
-
-
Fernando, R.I.1
Wimalasena, J.2
-
45
-
-
0042971700
-
PTEN induces cell cycle arrest by decreasing the level and nuclear localization of cyclin D1
-
Radu A., Neubauer V., Akagi T., Hanafusa H., and Georgescu M.M. PTEN induces cell cycle arrest by decreasing the level and nuclear localization of cyclin D1. Mol. Cell Biol. 23 (2003) 6139-6149
-
(2003)
Mol. Cell Biol.
, vol.23
, pp. 6139-6149
-
-
Radu, A.1
Neubauer, V.2
Akagi, T.3
Hanafusa, H.4
Georgescu, M.M.5
-
46
-
-
0032575348
-
Promotion of microtubule assembly by oligocations: cooperativity between charged groups
-
Wolff J. Promotion of microtubule assembly by oligocations: cooperativity between charged groups. Biochemistry 37 (1998) 10722-10729
-
(1998)
Biochemistry
, vol.37
, pp. 10722-10729
-
-
Wolff, J.1
-
47
-
-
0034743675
-
Structural insight into microtubule function
-
Nogales E. Structural insight into microtubule function. Annu. Rev. Biophys. Biomol. Struct. 30 (2001) 397-420
-
(2001)
Annu. Rev. Biophys. Biomol. Struct.
, vol.30
, pp. 397-420
-
-
Nogales, E.1
-
48
-
-
0035163237
-
Cooperative control of Akt phosphorylation, bcl-2 expression, and apoptosis by cytoskeletal microfilaments and microtubules in capillary endothelial cells
-
Flusberg D.A., Numaguchi Y., and Ingber D.E. Cooperative control of Akt phosphorylation, bcl-2 expression, and apoptosis by cytoskeletal microfilaments and microtubules in capillary endothelial cells. Mol. Biol. Cell 12 (2001) 3087-3094
-
(2001)
Mol. Biol. Cell
, vol.12
, pp. 3087-3094
-
-
Flusberg, D.A.1
Numaguchi, Y.2
Ingber, D.E.3
-
49
-
-
0141996464
-
Microtubules, microtubule-interfering agents and apoptosis
-
Mollinedo F., and Gajate C. Microtubules, microtubule-interfering agents and apoptosis. Apoptosis 8 (2003) 413-450
-
(2003)
Apoptosis
, vol.8
, pp. 413-450
-
-
Mollinedo, F.1
Gajate, C.2
-
50
-
-
0036304838
-
G(1) and G(2) cell-cycle arrest following microtubule depolymerization in human breast cancer cells
-
Blajeski A.L., Phan V.A., Kottke T.J., and Kaufmann S.H. G(1) and G(2) cell-cycle arrest following microtubule depolymerization in human breast cancer cells. J. Clin. Invest. 110 (2002) 91-99
-
(2002)
J. Clin. Invest.
, vol.110
, pp. 91-99
-
-
Blajeski, A.L.1
Phan, V.A.2
Kottke, T.J.3
Kaufmann, S.H.4
-
51
-
-
0033559550
-
Polyamine analogue induction of the p53-p21WAF1/CIP1-Rb pathway and G1 arrest in human melanoma cells
-
Kramer D.L., Vujcic S., Diegelman P., Alderfer J., Miller J.T., Black J.D., Bergeron R.J., and Porter C.W. Polyamine analogue induction of the p53-p21WAF1/CIP1-Rb pathway and G1 arrest in human melanoma cells. Cancer Res. 59 (1999) 1278-1286
-
(1999)
Cancer Res.
, vol.59
, pp. 1278-1286
-
-
Kramer, D.L.1
Vujcic, S.2
Diegelman, P.3
Alderfer, J.4
Miller, J.T.5
Black, J.D.6
Bergeron, R.J.7
Porter, C.W.8
-
52
-
-
0035881568
-
Phosphatidylinositol-3-OH Kinase (PI3K)/AKT2, activated in breast cancer, regulates and is induced by estrogen receptor alpha (ERalpha) via interaction between ERalpha and PI3K
-
Sun M., Paciga J.E., Feldman R.I., Yuan Z., Coppola D., Lu Y.Y., Shelley S.A., Nicosia S.V., and Cheng J.Q. Phosphatidylinositol-3-OH Kinase (PI3K)/AKT2, activated in breast cancer, regulates and is induced by estrogen receptor alpha (ERalpha) via interaction between ERalpha and PI3K. Cancer Res. 61 (2001) 5985-5991
-
(2001)
Cancer Res.
, vol.61
, pp. 5985-5991
-
-
Sun, M.1
Paciga, J.E.2
Feldman, R.I.3
Yuan, Z.4
Coppola, D.5
Lu, Y.Y.6
Shelley, S.A.7
Nicosia, S.V.8
Cheng, J.Q.9
-
53
-
-
0038542892
-
Identification of genes regulated by 2-methoxyestradiol (2ME2) in multiple myeloma cells using oligonucleotide arrays
-
Chauhan D., Li G., Auclair D., Hideshima T., Richardson P., Podar K.N., et al. Identification of genes regulated by 2-methoxyestradiol (2ME2) in multiple myeloma cells using oligonucleotide arrays. Blood 101 (2003) 3606-3614
-
(2003)
Blood
, vol.101
, pp. 3606-3614
-
-
Chauhan, D.1
Li, G.2
Auclair, D.3
Hideshima, T.4
Richardson, P.5
Podar, K.N.6
-
55
-
-
19844369277
-
2-Methoxyestradiol-induced apoptosis in human leukemia cells proceeds through a reactive oxygen species and Akt-dependent process
-
Gao N., Rahmani M., Dent P., and Grant S. 2-Methoxyestradiol-induced apoptosis in human leukemia cells proceeds through a reactive oxygen species and Akt-dependent process. Oncogene 24 (2005) 3797-3809
-
(2005)
Oncogene
, vol.24
, pp. 3797-3809
-
-
Gao, N.1
Rahmani, M.2
Dent, P.3
Grant, S.4
-
56
-
-
33744955627
-
17 Beta-estradiol protects against oxidative stress-induced cell death through the glutathione/glutaredoxin-dependent redox regulation of Akt in myocardiac H9c2 cells
-
Urata Y., Ihara Y., Murata H., Goto S., Koji T., Yodoi J., Inoue S., and Kondo T. 17 Beta-estradiol protects against oxidative stress-induced cell death through the glutathione/glutaredoxin-dependent redox regulation of Akt in myocardiac H9c2 cells. J. Biol. Chem. 281 (2006) 13092-13102
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 13092-13102
-
-
Urata, Y.1
Ihara, Y.2
Murata, H.3
Goto, S.4
Koji, T.5
Yodoi, J.6
Inoue, S.7
Kondo, T.8
|