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Volumn , Issue , 2005, Pages 169-179

Glutamate and schizophrenia and the n-methyl-d-aspartate receptor hypofunction hypothesis

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EID: 33947680928     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-1-59259-852-6_7     Document Type: Chapter
Times cited : (4)

References (89)
  • 1
    • 0021998845 scopus 로고
    • A family study of schizophrenic and normal control probands: Implications for the spectrum concept of schizophrenia
    • Baron M, Grün R, Rainer JD. A family study of schizophrenic and normal control probands: implications for the spectrum concept of schizophrenia. Am J Psychiatry 1985; 142: 447-455.
    • (1985) Am J Psychiatry , vol.142 , pp. 447-455
    • Baron, M.1    Grün, R.2    Rainer, J.D.3
  • 3
    • 0013937338 scopus 로고
    • Psychiatric disorders in faster home reared children of schizophrenic mothers
    • Heston LL. Psychiatric disorders in faster home reared children of schizophrenic mothers. Br J Psychiatry 1966; 112:819-827.
    • (1966) Br J Psychiatry , vol.112 , pp. 819-827
    • Heston, L.L.1
  • 4
    • 78651116398 scopus 로고
    • Effect of chlorpromazine and haloperidol on the formation of 3-methoxytyramine and normetanophrine in mouse brain
    • Carlsson A, Lindquist M. Effect of chlorpromazine and haloperidol on the formation of 3-methoxytyramine and normetanophrine in mouse brain. Acta Pharmacol 1963; 20:140-144.
    • (1963) Acta Pharmacol , vol.20 , pp. 140-144
    • Carlsson, A.1    Lindquist, M.2
  • 7
    • 0027485692 scopus 로고
    • Dopamine D4 receptors elevated in schizophrenia
    • Seeman P, Guan HC, Van Tol HH. Dopamine D4 receptors elevated in schizophrenia. Nature 1993; 365(6445):441-445.
    • (1993) Nature , vol.365 , Issue.6445 , pp. 441-445
    • Seeman, P.1    Guan, H.C.2    Van Tol, H.H.3
  • 8
    • 0025194556 scopus 로고
    • D2 dopamine receptors in neuroleptic-naive schizophrenic patients. A positron emission tomography study with [11C]raclopride
    • Farde L, Wiesel FA, Stone-Elander S, et al. D2 dopamine receptors in neuroleptic-naive schizophrenic patients. A positron emission tomography study with [11C]raclopride. Arch Gen Psychiatry 1990; 47:213-219.
    • (1990) Arch Gen Psychiatry , vol.47 , pp. 213-219
    • Farde, L.1    Wiesel, F.A.2    Stone-Elander, S.3
  • 9
    • 0030152624 scopus 로고    scopus 로고
    • The relative abundance of dopamine D4 receptor mRNA in post mortem brains of schizophrenics and controls
    • Roberts DA, Balderson D, Pickering-Brown SM, Deakin JF, Owen F. The relative abundance of dopamine D4 receptor mRNA in post mortem brains of schizophrenics and controls. Schizophr Res 1996; 20:171-174.
    • (1996) Schizophr Res , vol.20 , pp. 171-174
    • Roberts, D.A.1    Balderson, D.2    Pickering-Brown, S.M.3    Deakin, J.F.4    Owen, F.5
  • 10
    • 0024567420 scopus 로고
    • 3H-Spiperone binding sites in postmortem brains from schizophrenic patients:relationship to neuroleptic drug treatment, abnormal movements, and positive symptoms
    • 3H-Spiperone binding sites in postmortem brains from schizophrenic patients:relationship to neuroleptic drug treatment, abnormal movements, and positive symptoms. J Neural Transm 1989; 75:1-10.
    • (1989) J Neural Transm , vol.75 , pp. 1-10
    • Kornhuber, J.1    Riederer, P.2    Reynolds, G.P.3    Beckmann, H.4    Jellinger, K.5    Gabriel, E.6
  • 12
    • 0017172562 scopus 로고
    • Possible association of schizophrenia with a disturbance in prostaglandin metabolism. A physiological hypothesis
    • Feldberg W. Possible association of schizophrenia with a disturbance in prostaglandin metabolism. A physiological hypothesis. Psychol Med 1976; 6:359-369.
    • (1976) Psychol Med , vol.6 , pp. 359-369
    • Feldberg, W.1
  • 13
    • 0017786205 scopus 로고
    • Schizophrenia as a prostaglandin deficiency disease
    • Horrobin DF Schizophrenia as a prostaglandin deficiency disease. Lancet 1977; I: 936-937.
    • (1977) Lancet , vol.1 , pp. 936-937
    • Horrobin, D.F.1
  • 14
    • 0021261114 scopus 로고
    • A re-evaluation of the viral hypothesis: Is psychosis the result of retroviral integration at a side close to the cerebral dominance gene?
    • Crow TJ. A re-evaluation of the viral hypothesis: is psychosis the result of retroviral integration at a side close to the cerebral dominance gene? Br J Psychiatry 1984; 145:243-253.
    • (1984) Br J Psychiatry , vol.145 , pp. 243-253
    • Crow, T.J.1
  • 15
    • 0024427903 scopus 로고
    • Beyond the dopamine hypothesis. The neurochemical pathology of schizophrenia
    • Reynolds GP. Beyond the dopamine hypothesis. The neurochemical pathology of schizophrenia. Br J Psychiatry 1989; 155:305-316.
    • (1989) Br J Psychiatry , vol.155 , pp. 305-316
    • Reynolds, G.P.1
  • 16
    • 0027160593 scopus 로고
    • Neurochemistry and neuroendocrinology of schizophrenia: A selective review
    • Lieberman JA, Koreen AR. Neurochemistry and neuroendocrinology of schizophrenia: a selective review. Schizophr Bull 1993; 19:371-429.
    • (1993) Schizophr Bull , vol.19 , pp. 371-429
    • Lieberman, J.A.1    Koreen, A.R.2
  • 17
    • 0028053555 scopus 로고
    • Aktueller Stand der biochemischen Hypothesen zur Pathogenese der Schizophrenien
    • Kornhuber J, Weller M. Aktueller Stand der biochemischen Hypothesen zur Pathogenese der Schizophrenien. Nervenarzt 1994; 65:741-754.
    • (1994) Nervenarzt , vol.65 , pp. 741-754
    • Kornhuber, J.1    Weller, M.2
  • 18
    • 0019293020 scopus 로고
    • Low cerebrospinal fluid gluta-mate in schizophrenic patients and a new hypothesis on schizophrenia
    • Kim JS, Kornhuber HH, Schmid-Burgk W, Holzmüller B. Low cerebrospinal fluid gluta-mate in schizophrenic patients and a new hypothesis on schizophrenia. Neurosci Lett 1980; 20:379-382.
    • (1980) Neurosci Lett , vol.20 , pp. 379-382
    • Kim, J.S.1    Kornhuber, H.H.2    Schmid-Burgk, W.3    Holzmüller, B.4
  • 20
    • 84891387577 scopus 로고    scopus 로고
    • Modellvorstellungen zur Ätiopathogenese der Schizophrenien
    • Riederer P, Laux G, Pöldinger W, eds., Wien: Springer Verlag
    • Kornhuber J, Thome J, Riederer P. Modellvorstellungen zur Ätiopathogenese der Schizophrenien. In: Riederer P, Laux G, Pöldinger W, eds. Neuro-Psychopharmaka, Bd. 4, 2. Auflage. Wien: Springer Verlag, 1998.
    • (1998) Neuro-Psychopharmaka Bd. 4, 2. Auflage
    • Kornhuber, J.1    Thome, J.2    Riederer, P.3
  • 22
    • 0002572342 scopus 로고
    • Neurotransmitter aberrations in schizophrenia: New findings
    • Fog R, Gerlach J, Hemmingsen R, eds., Copenhagen: Munksgaard
    • Carlsson A, Waters N, Hansson LO. Neurotransmitter aberrations in schizophrenia: new findings. In:Fog R, Gerlach J, Hemmingsen R, eds. Schizophrenia. An Integrated View. Copenhagen: Munksgaard, 1995:332-340.
    • (1995) Schizophrenia. An Integrated View , pp. 332-340
    • Carlsson, A.1    Waters, N.2    Hansson, L.O.3
  • 23
    • 0026748415 scopus 로고
    • Interaction between glutamatergic and dopaminergic tone in the nucleus accumbens of mice: Evidence for a dual glutamatergic function with respect to psychomotor control
    • Svensson A, Carlsson ML, Carlsson A. Interaction between glutamatergic and dopaminergic tone in the nucleus accumbens of mice: evidence for a dual glutamatergic function with respect to psychomotor control. J Neural Transm 1992; 88:235-240.
    • (1992) J Neural Transm , vol.88 , pp. 235-240
    • Svensson, A.1    Carlsson, M.L.2    Carlsson, A.3
  • 24
    • 0028875197 scopus 로고
    • Abnormal excitatory neurotransmitter metabolism in schizophrenic brains
    • Tsai G, Passani LA, Slusher BS, et al. Abnormal excitatory neurotransmitter metabolism in schizophrenic brains. Arch Gen Psychiatry 1995; 52:829-836.
    • (1995) Arch Gen Psychiatry , vol.52 , pp. 829-836
    • Tsai, G.1    Passani, L.A.2    Slusher, B.S.3
  • 27
    • 0026696198 scopus 로고
    • In vitro and in vivo inhibition of Af-acetyl-L-aspartyl-L-glutamate catabolism by,/V-acylated L-glutamate analogs
    • Serval V, Galli T, Cheramy A, Glowinski J, Lavielle S. In vitro and in vivo inhibition of Af-acetyl-L-aspartyl-L-glutamate catabolism by,/V-acylated L-glutamate analogs. J Pharmacol Exp Ther 1992; 260:1093-1100.
    • (1992) J Pharmacol Exp Ther , vol.260 , pp. 1093-1100
    • Serval, V.1    Galli, T.2    Cheramy, A.3    Glowinski, J.4    Lavielle, S.5
  • 28
    • 0037977113 scopus 로고    scopus 로고
    • Decreased serum levels of D-serine in patients with schizophrenia: Evidence in support of the A'-methyl-D-aspartate receptor hypo-function hypothesis of schizophrenia
    • Hashimoto K, Fukushima T, Shimizu E, et al. Decreased serum levels of D-serine in patients with schizophrenia: evidence in support of the A'-methyl-D-aspartate receptor hypo-function hypothesis of schizophrenia. Arch Gen Psychiatry 2003; 60:572-576.
    • (2003) Arch Gen Psychiatry , vol.60 , pp. 572-576
    • Hashimoto, K.1    Fukushima, T.2    Shimizu, E.3
  • 29
    • 0001643769 scopus 로고    scopus 로고
    • Riederer P, Laux G, Pöldinger W, eds, Wien: Springer
    • Kornhuber J, Bleich S. Memantin. In: Riederer P, Laux G, Pöldinger W, eds. Neuro-Psychopharmaka. Wien: Springer, 1999:687-704.
    • (1999) Neuro-Psychopharmaka , pp. 687-704
    • Kornhuber, J.1    Memantin, B.S.2
  • 30
    • 0031048111 scopus 로고    scopus 로고
    • Psychotogenicity and NMDA receptor antagonism: Implications for neuroprotective pharmacotherapy
    • Kornhuber J, Weller M. Psychotogenicity and NMDA receptor antagonism: implications for neuroprotective pharmacotherapy. Biol Psychiatry 1997; 41:135-144.
    • (1997) Biol Psychiatry , vol.41 , pp. 135-144
    • Kornhuber, J.1    Weller, M.2
  • 31
    • 0019366734 scopus 로고
    • Psychiatric and medical syndromes with phencyclidine (PCP) abuse
    • Pearlson GD. Psychiatric and medical syndromes with phencyclidine (PCP) abuse. Johns Hopkins Med J 1981; 148:25-33.
    • (1981) Johns Hopkins Med J , vol.148 , pp. 25-33
    • Pearlson, G.D.1
  • 32
    • 0025952455 scopus 로고
    • Recent advances in the phencyclidine model of schizophrenia
    • Javitt DC, Zukin SR. Recent advances in the phencyclidine model of schizophrenia. Am J Psychiatry 1991; 148:1301-1308.
    • (1991) Am J Psychiatry , vol.148 , pp. 1301-1308
    • Javitt, D.C.1    Zukin, S.R.2
  • 33
    • 0344404408 scopus 로고    scopus 로고
    • Increased density of glutamate/Af-methyl-D-aspartate receptors in putamen from schizophrenic patients
    • Aparicio-Legarza MI, Davis B, Hutson PH, Reynolds GP. Increased density of glutamate/Af-methyl-D-aspartate receptors in putamen from schizophrenic patients. Neurosci Lett 1998; 241:43-146.
    • (1998) Neurosci Lett , vol.241 , pp. 43-146
    • Aparicio-Legarza, M.I.1    Davis, B.2    Hutson, P.H.3    Reynolds, G.P.4
  • 34
    • 0033914752 scopus 로고    scopus 로고
    • Ionotropic glutamate receptors and expression of,/V-methyl-D-aspartate receptor subunits in subregions of human hippocampus: Effects of schizophrenia
    • Gao XM, Sakai K, Roberts RC, Conley RR, Dean B, Tamminga CA. Ionotropic glutamate receptors and expression of,/V-methyl-D-aspartate receptor subunits in subregions of human hippocampus: effects of schizophrenia. Am J Psychiatry 2000;157:1141-1149.
    • (2000) Am J Psychiatry , vol.157 , pp. 1141-1149
    • Gao, X.M.1    Sakai, K.2    Roberts, R.C.3    Conley, R.R.4    Dean, B.5    Tamminga, C.A.6
  • 35
    • 0031017606 scopus 로고    scopus 로고
    • GluR2 glutamate receptor subunit flip and flop iso-forms are decreased in the hippocampal formation in schizophrenia: A reverse transcriptase-polymerase chain reaction (RT-PCR) study
    • Eastwood SL, Burnet PW, Harrison PJ. GluR2 glutamate receptor subunit flip and flop iso-forms are decreased in the hippocampal formation in schizophrenia: a reverse transcriptase-polymerase chain reaction (RT-PCR) study. Brain Res Mol Brain Res 1997; 44:92-98.
    • (1997) Brain Res Mol Brain Res , vol.44 , pp. 92-98
    • Eastwood, S.L.1    Burnet, P.W.2    Harrison, P.J.3
  • 36
    • 0033588176 scopus 로고    scopus 로고
    • Mice with reduced NMDA receptor expression display behaviours related to schizophrenia
    • Mohn AR, Gainetdinov RR, Caron MG, Koller BH. Mice with reduced NMDA receptor expression display behaviours related to schizophrenia. Cell 1999; 98:427-436.
    • (1999) Cell , vol.98 , pp. 427-436
    • Mohn, A.R.1    Gainetdinov, R.R.2    Caron, M.G.3    Koller, B.H.4
  • 37
    • 0036703884 scopus 로고    scopus 로고
    • Severe impairment of NMDA receptor function in mice carrying targeted point mutations in the glycine binding site results in drug-resistant nonhabituating hyperactivity
    • Ballard TM, Pauly-Evers M, Higgins GA, et al. Severe impairment of NMDA receptor function in mice carrying targeted point mutations in the glycine binding site results in drug-resistant nonhabituating hyperactivity. J Neurosci 2002; 22:6713-6723.
    • (2002) J Neurosci , vol.22 , pp. 6713-6723
    • Ballard, T.M.1    Pauly-Evers, M.2    Higgins, G.A.3
  • 38
    • 0028813106 scopus 로고
    • Reduced hippocampal LTP and spatial learning in mice lacking NMDA receptor epsilon 1 subunit
    • Sakimura K, Kutsuwada T, Ito I, et al. Reduced hippocampal LTP and spatial learning in mice lacking NMDA receptor epsilon 1 subunit. Nature 1995; 373:151-155.
    • (1995) Nature , vol.373 , pp. 151-155
    • Sakimura, K.1    Kutsuwada, T.2    Ito, I.3
  • 39
    • 0035862965 scopus 로고    scopus 로고
    • Hyperfunction of dopaminergic and serotonergic neuronal systems in mice lacking the NMDA receptor epsilon1 subunit
    • Miyamoto Y, Yamada K, Noda Y, Mori H, Mishina M, Nabeshima T. Hyperfunction of dopaminergic and serotonergic neuronal systems in mice lacking the NMDA receptor epsilon1 subunit. J Neurosci 2001; 21:750-757.
    • (2001) J Neurosci , vol.21 , pp. 750-757
    • Miyamoto, Y.1    Yamada, K.2    Noda, Y.3    Mori, H.4    Mishina, M.5    Nabeshima, T.6
  • 40
  • 41
    • 0031004644 scopus 로고    scopus 로고
    • Immunoautoradiographic evidence for a loss of alpha-amino-3-hydroxy-5- methyl-4-isoxazole propionate-preferring non-A'-methyl-D-aspartate glutamate receptors within the medial temporal lobe in schizophrenia
    • Eastwood SL, Kerwin RW, Harrison PJ. Immunoautoradiographic evidence for a loss of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate-preferring non-A'-methyl-D-aspartate glutamate receptors within the medial temporal lobe in schizophrenia. Biol Psychiatry 1997; 41:636-643.
    • (1997) Biol Psychiatry , vol.41 , pp. 636-643
    • Eastwood, S.L.1    Kerwin, R.W.2    Harrison, P.J.3
  • 42
    • 0025967753 scopus 로고
    • Decreased hippocampal expression of a glutamate receptor gene in schizophrenia
    • Harrison PJ, McLaughlin D, Kerwin RW. Decreased hippocampal expression of a glutamate receptor gene in schizophrenia. Lancet 1991; 337:450-452.
    • (1991) Lancet , vol.337 , pp. 450-452
    • Harrison, P.J.1    McLaughlin, D.2    Kerwin, R.W.3
  • 43
    • 0025221418 scopus 로고
    • Quantitative autoradiographic analysis of glutamate binding sites in the hippocampal formation in normal and schizophrenic brain post mortem
    • Kerwin R, Patel S, Meldrum B. Quantitative autoradiographic analysis of glutamate binding sites in the hippocampal formation in normal and schizophrenic brain post mortem. Neuroscience 1990; 39:25-32.
    • (1990) Neuroscience , vol.39 , pp. 25-32
    • Kerwin, R.1    Patel, S.2    Meldrum, B.3
  • 44
    • 0030933984 scopus 로고    scopus 로고
    • Distribution of kainate receptor subunit mRNAs in human hippocampus, neocortex and cerebellum, and bilateral reduction of hippocampal GluR6 and KA2 transcripts in schizophrenia
    • Porter RH, Eastwood SL, Harrison PJ. Distribution of kainate receptor subunit mRNAs in human hippocampus, neocortex and cerebellum, and bilateral reduction of hippocampal GluR6 and KA2 transcripts in schizophrenia. Brain Res 1997; 751:217-231.
    • (1997) Brain Res , vol.751 , pp. 217-231
    • Porter, R.H.1    Eastwood, S.L.2    Harrison, P.J.3
  • 45
    • 0024392625 scopus 로고
    • Frontal cortical and left temporal glutamatergic dysfunction in schizophrenia
    • Deakin JF, Slater P, Simpson MD, et al. Frontal cortical and left temporal glutamatergic dysfunction in schizophrenia. J Neurochem 1989; 52:1781-1786.
    • (1989) J Neurochem , vol.52 , pp. 1781-1786
    • Deakin, J.F.1    Slater, P.2    Simpson, M.D.3
  • 46
    • 0020644714 scopus 로고
    • 3H]kainic acid binding in the prefrontal cortex in schizophrenia
    • 3H]kainic acid binding in the prefrontal cortex in schizophrenia. Neurosci Lett 1983; 40:245-250.
    • (1983) Neurosci Lett , vol.40 , pp. 245-250
    • Nishikawa, T.1    Takashima, M.2    Toru, M.3
  • 48
    • 9044247065 scopus 로고    scopus 로고
    • Selective alterations in gene expression for NMDA receptor subunits in prefrontal cortex of schizophrenics
    • Akbarian S, Sucher NJ, Bradley D, et al. Selective alterations in gene expression for NMDA receptor subunits in prefrontal cortex of schizophrenics. J Neurosci 1996; 16:19-30.
    • (1996) J Neurosci , vol.16 , pp. 19-30
    • Akbarian, S.1    Sucher, N.J.2    Bradley, D.3
  • 49
    • 0033601963 scopus 로고    scopus 로고
    • NR2Bcontaining NMDA receptors are up-regulated in temporal cortex in schizophrenia
    • Grimwood S, Slater P, Deakin JF, Hutson PH. NR2Bcontaining NMDA receptors are up-regulated in temporal cortex in schizophrenia. Neuroreport 1999; 10:461-465.
    • (1999) Neuroreport , vol.10 , pp. 461-465
    • Grimwood, S.1    Slater, P.2    Deakin, J.F.3    Hutson, P.H.4
  • 50
    • 0035907143 scopus 로고    scopus 로고
    • Reynolds GP Increased density of glutamate/W-methyl-D-aspartate receptors in superior temporal cortex in schizophrenia
    • Nudmamud S, Reynolds GP Increased density of glutamate/W-methyl-D- aspartate receptors in superior temporal cortex in schizophrenia. Neurosci Lett 2001; 304:9-12.
    • (2001) Neurosci Lett , vol.304 , pp. 9-12
    • Nudmamud, S.1
  • 51
    • 0028928362 scopus 로고
    • Glutamate receptor subtype expression in human postmortem brain tissue from schizophrenics and alcohol abusers
    • Breese CR, Freedman R, Leonard SS. Glutamate receptor subtype expression in human postmortem brain tissue from schizophrenics and alcohol abusers. Brain Res 1995; 674:82-90.
    • (1995) Brain Res , vol.674 , pp. 82-90
    • Breese, C.R.1    Freedman, R.2    Leonard, S.S.3
  • 52
    • 1842298715 scopus 로고    scopus 로고
    • Glutamate receptors in the postmortem striatum of schizophrenic, suicide, and control brains
    • Noga JT, Hyde TM, Herman MM, et al. Glutamate receptors in the postmortem striatum of schizophrenic, suicide, and control brains. Synapse 1997; 27:168-176.
    • (1997) Synapse , vol.27 , pp. 168-176
    • Noga, J.T.1    Hyde, T.M.2    Herman, M.M.3
  • 53
    • 0028810181 scopus 로고
    • Developmental and regional expression pattern of a novel NMDA receptor-like subunit (NMDAR-L) in the rodent brain
    • Sucher NJ, Akbarian S, Chi CL, et al. Developmental and regional expression pattern of a novel NMDA receptor-like subunit (NMDAR-L) in the rodent brain. J Neurosci 1995; 15:6509-6520.
    • (1995) J Neurosci , vol.15 , pp. 6509-6520
    • Sucher, N.J.1    Akbarian, S.2    Chi, C.L.3
  • 54
    • 0034068655 scopus 로고    scopus 로고
    • Attenuation of specific PCP-evoked behaviors by the potent mGlu2/3 receptor agonist, LY379268 and comparison with the atypical antipsychotic, clozapine
    • Cartmell J, Monn JA, Schoepp DD. Attenuation of specific PCP-evoked behaviors by the potent mGlu2/3 receptor agonist, LY379268 and comparison with the atypical antipsychotic, clozapine. Psychopharmacology 2000; 148:423-429.
    • (2000) Psychopharmacology , vol.148 , pp. 423-429
    • Cartmell, J.1    Monn, J.A.2    Schoepp, D.D.3
  • 55
    • 0032929398 scopus 로고    scopus 로고
    • Intracerebral administration of metabotropic glutamate receptor agonists disrupts prepulse inhibition of acoustic startle in Sprague-Dawley rats
    • Grauer SM, Marquis KL. Intracerebral administration of metabotropic glutamate receptor agonists disrupts prepulse inhibition of acoustic startle in Sprague-Dawley rats. Psychopharmacology 1999; 141:405-412.
    • (1999) Psychopharmacology , vol.141 , pp. 405-412
    • Grauer, S.M.1    Marquis, K.L.2
  • 56
    • 0036176446 scopus 로고    scopus 로고
    • Comparative analysis of group II metabotropic glutamate receptor immunoreactivity in Brodmann's area 46 of the dorsolateral prefrontal cortex from patients with schizophrenia and normal subjects
    • Crook JM, Akil M, Law BC, Hyde TM, Kleinman JE. Comparative analysis of group II metabotropic glutamate receptor immunoreactivity in Brodmann's area 46 of the dorsolateral prefrontal cortex from patients with schizophrenia and normal subjects. Mol Psychiatry 2002; 7:157-164.
    • (2002) Mol Psychiatry , vol.7 , pp. 157-164
    • Crook, J.M.1    Akil, M.2    Law, B.C.3    Hyde, T.M.4    Kleinman, J.E.5
  • 57
    • 0032078391 scopus 로고    scopus 로고
    • Expression of the human excitatory amino acid transporter 2 and metabotropic glutamate receptors 3 and 5 in the prefrontal cortex from normal individuals and patients with schizophrenia
    • Ohnuma T, Augood SJ, Arai H, McKenna PJ, Emson PC. Expression of the human excitatory amino acid transporter 2 and metabotropic glutamate receptors 3 and 5 in the prefrontal cortex from normal individuals and patients with schizophrenia. Brain Res Mol Brain Res 1998; 56:207-217.
    • (1998) Brain Res Mol Brain Res , vol.56 , pp. 207-217
    • Ohnuma, T.1    Augood, S.J.2    Arai, H.3    McKenna, P.J.4    Emson, P.C.5
  • 59
    • 0035056929 scopus 로고    scopus 로고
    • The genomic organisation of the metabotropic glutamate receptor subtype 5 gene, and its association with schizophrenia
    • Devon RS, Anderson S, Teague PW, et al. The genomic organisation of the metabotropic glutamate receptor subtype 5 gene, and its association with schizophrenia. Mol Psychiatry 2001; 6:311-314.
    • (2001) Mol Psychiatry , vol.6 , pp. 311-314
    • Devon, R.S.1    Anderson, S.2    Teague, P.W.3
  • 60
    • 0035863275 scopus 로고    scopus 로고
    • Polymorphisms in the genes for mGluR types 7 and 8: Association studies with schizophrenia
    • Bolonna AA, Kerwin RW, Munro J, Arranz MJ, Makoff AJ. Polymorphisms in the genes for mGluR types 7 and 8: association studies with schizophrenia. Schizophr Res 2001; 47:99-103.
    • (2001) Schizophr Res , vol.47 , pp. 99-103
    • Bolonna, A.A.1    Kerwin, R.W.2    Munro, J.3    Arranz, M.J.4    Makoff, A.J.5
  • 61
    • 0035112644 scopus 로고    scopus 로고
    • Structure and polymorphisms of the human metabotropic glutamate receptor type 2 gene (GRM2): Analysis of association with schizophrenia
    • Joo A, Shibata H, Ninomiya H, Kawasaki H, Tashiro N, Fukumaki Y. Structure and polymorphisms of the human metabotropic glutamate receptor type 2 gene (GRM2): analysis of association with schizophrenia. Mol Psychiatry 2001; 6:186-192.
    • (2001) Mol Psychiatry , vol.6 , pp. 186-192
    • Joo, A.1    Shibata, H.2    Ninomiya, H.3    Kawasaki, H.4    Tashiro, N.5    Fukumaki, Y.6
  • 62
    • 0034940397 scopus 로고    scopus 로고
    • Mutation screening of the metabotropic glutamate receptor mGluR4 (GRM4) gene in patients with schizophrenia
    • Ohtsuki T, Toru M, Arinami T. Mutation screening of the metabotropic glutamate receptor mGluR4 (GRM4) gene in patients with schizophrenia. Psychiatr Genet 2001; 11:79-83.
    • (2001) Psychiatr Genet , vol.11 , pp. 79-83
    • Ohtsuki, T.1    Toru, M.2    Arinami, T.3
  • 63
    • 0032457339 scopus 로고    scopus 로고
    • Selective abolition of the NMDA component of long-term potentiation in mice lacking mGluR5
    • Jia Z, Lu Y, Henderson J, Taverna F, et al. Selective abolition of the NMDA component of long-term potentiation in mice lacking mGluR5. Learn Mem 1998; 5:331-343.
    • (1998) Learn Mem , vol.5 , pp. 331-343
    • Jia, Z.1    Lu, Y.2    Henderson, J.3    Taverna, F.4
  • 64
    • 0035959976 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor 5 mediates the potentiation of,/V-methyl-D-aspartate responses in medium spiny striatal neurons
    • Pisani A, Gubellini P, Bonsi P, et al. Metabotropic glutamate receptor 5 mediates the potentiation of,/V-methyl-D-aspartate responses in medium spiny striatal neurons. Neuroscience 2001; 106:579-587.
    • (2001) Neuroscience , vol.106 , pp. 579-587
    • Pisani, A.1    Gubellini, P.2    Bonsi, P.3
  • 65
    • 0032575715 scopus 로고    scopus 로고
    • Reversal of phencyclidine effects by group II metabotropic glutamate receptor agonist in rats
    • Moghaddam B, Adams BW. Reversal of phencyclidine effects by group II metabotropic glutamate receptor agonist in rats. Science 1998; 281:1349-1352.
    • (1998) Science , vol.281 , pp. 1349-1352
    • Moghaddam, B.1    Adams, B.W.2
  • 66
    • 0025249952 scopus 로고
    • Potkin SG An open trial of glycine as an adjunct to neuroleptics in chronic treatment-refractory schizophrenics
    • Costa J, Khaled E, Sramek J, Bunney W Jr, Potkin SG An open trial of glycine as an adjunct to neuroleptics in chronic treatment-refractory schizophrenics. J Clin Psychophar-macol 1990; 10:71-72.
    • (1990) J Clin Psychophar-macol , vol.10 , pp. 71-72
    • Costa, J.1    Khaled, E.2    Sramek, J.3    Bunney Jr., W.4
  • 67
    • 0024286543 scopus 로고
    • Glycine therapy of schizophrenia
    • Waziri R. Glycine therapy of schizophrenia. Biol Psychiatry 1988; 23:210-211.
    • (1988) Biol Psychiatry , vol.23 , pp. 210-211
    • Waziri, R.1
  • 69
    • 0014707413 scopus 로고
    • D-Cycloserine therapy of psychosis by symptom provocation
    • Simeon J, Fink M, Itil TM, Ponce D. D-Cycloserine therapy of psychosis by symptom provocation. Compr Psychiatry 1970; 11:80-88.
    • (1970) Compr Psychiatry , vol.11 , pp. 80-88
    • Simeon, J.1    Fink, M.2    Itil, T.M.3    Ponce, D.4
  • 70
    • 0028174008 scopus 로고
    • D-cycloserine adjuvant therapy to conventional neuroleptic treatment in schizophrenia: An open-label study
    • Cascella NG, Macciardi F, Cavallini C, Smeraldi E. D-cycloserine adjuvant therapy to conventional neuroleptic treatment in schizophrenia: an open-label study. J Neural Transm Gen Sect 1994; 95:105-111.
    • (1994) J Neural Transm Gen Sect , vol.95 , pp. 105-111
    • Cascella, N.G.1    MacCiardi, F.2    Cavallini, C.3    Smeraldi, E.4
  • 71
    • 0028015607 scopus 로고
    • Lindenmayer JP Amelioration of negative symptoms in schizophrenia by glycine
    • Javitt DC, Zylberman I, Zukin SR, Heresco-Levy U, Lindenmayer JP Amelioration of negative symptoms in schizophrenia by glycine. Am J Psychiatry 1994; 151:1234-1236.
    • (1994) Am J Psychiatry , vol.151 , pp. 1234-1236
    • Javitt, D.C.1    Zylberman, I.2    Zukin, S.R.3    Heresco-Levy, U.4
  • 72
    • 0033558578 scopus 로고    scopus 로고
    • Reversal of phency-clidine-induced effects by glycine and glycine transport inhibitors
    • A.E. Bennett Research Award
    • Javitt DC, Balla A, Sershen H, Lajtha A. A.E. Bennett Research Award. Reversal of phency-clidine-induced effects by glycine and glycine transport inhibitors. Biol Psychiatry 1999; 45:668-679.
    • (1999) Biol Psychiatry , vol.45 , pp. 668-679
    • Javitt, D.C.1    Balla, A.2    Sershen, H.3    Lajtha, A.4
  • 73
    • 0034025767 scopus 로고    scopus 로고
    • Excitatory amino acid agonists and antagonists: Pharmacology and therapeutic applications
    • Trist DG Excitatory amino acid agonists and antagonists: pharmacology and therapeutic applications. Pharm Acta Helv 2000; 74:221-229.
    • (2000) Pharm Acta Helv , vol.74 , pp. 221-229
    • Trist, D.G.1
  • 74
    • 0036184549 scopus 로고    scopus 로고
    • Placebo-controlled trial of D-cycloserine added to conventional neuroleptics, olanzapine, or risperidone in schizophrenia
    • Heresco-Levy U, Ermilov M, Shimoni J, Shapira B, Silipo G, Javitt DC. Placebo-controlled trial of D-cycloserine added to conventional neuroleptics, olanzapine, or risperidone in schizophrenia. Am J Psychiatry 2002; 159:480-482.
    • (2002) Am J Psychiatry , vol.159 , pp. 480-482
    • Heresco-Levy, U.1    Ermilov, M.2    Shimoni, J.3    Shapira, B.4    Silipo, G.5    Javitt, D.C.6
  • 76
    • 0013085913 scopus 로고    scopus 로고
    • N-methyl-D-aspartate receptor-coupled glycineB receptors in the pathogenesis and treatment of schizophrenia: A critical review
    • Millan MJ. N-methyl-D-aspartate receptor-coupled glycineB receptors in the pathogenesis and treatment of schizophrenia: a critical review. Curr Drug Target CNS Neurol Disord 2002; 1:191-213.
    • (2002) Curr Drug Target CNS Neurol Disord , vol.1 , pp. 191-213
    • Millan, M.J.1
  • 77
    • 0024247522 scopus 로고
    • The current status of the dopamine hypothesis of schizophrenia
    • Carlsson A. The current status of the dopamine hypothesis of schizophrenia. Neuropsy-chopharmacology 1988; 1:179-186.
    • (1988) Neuropsy-chopharmacology , vol.1 , pp. 179-186
    • Carlsson, A.1
  • 79
    • 0024321406 scopus 로고
    • Cholinergic hyperactivity and negative schizophrenic symptoms. A model of cholinergic/dopaminergic interactions in schizophrenia
    • Tandon R, Greden JF. Cholinergic hyperactivity and negative schizophrenic symptoms. A model of cholinergic/dopaminergic interactions in schizophrenia. Arch Gen Psychiatry 1989; 46:745-753.
    • (1989) Arch Gen Psychiatry , vol.46 , pp. 745-753
    • Tandon, R.1    Greden, J.F.2
  • 80
    • 0020517607 scopus 로고
    • The interaction between GABA and dopamine: Implications for schizophrenia
    • Garbutt JC, van Kammen DP. The interaction between GABA and dopamine: implications for schizophrenia. Schizophr Bull 1983; 9:336-353.
    • (1983) Schizophr Bull , vol.9 , pp. 336-353
    • Garbutt, J.C.1    Van Kammen, D.P.2
  • 81
    • 0024468417 scopus 로고
    • Clinical studies on the mechanism of action of clozapine: The dopamine-sero-tonin hypothesis of schizophrenia
    • Meltzer H Y. Clinical studies on the mechanism of action of clozapine: the dopamine-sero-tonin hypothesis of schizophrenia. Psychopharmacology 1989; 99:S18-S27.
    • (1989) Psychopharmacology , vol.99
    • Meltzer, H.Y.1
  • 82
    • 0025638911 scopus 로고
    • Adenosinergic psychopharmaceuticals: Just an extra cup of coffee?
    • Deckert J, Gleiter CH. Adenosinergic psychopharmaceuticals: just an extra cup of coffee? J Psychopharmacol 1990; 4:183-187.
    • (1990) J Psychopharmacol , vol.4 , pp. 183-187
    • Deckert, J.1    Gleiter, C.H.2
  • 83
    • 0022973392 scopus 로고
    • Cholecystokinin and schizophrenia
    • van Ree JM, Matthysse S, eds., Amsterdam: Elsevier, 1994
    • Nair NPV, Lal S, Bloom DM (1994). Cholecystokinin and schizophrenia. In: van Ree JM, Matthysse S, eds. Progress in Brain Research. Vol. 65. Amsterdam: Elsevier, 1994:237-258.
    • (1994) Progress in Brain Research , vol.65 , pp. 237-258
    • Nair, N.P.V.1    Lal, S.2    Bloom, D.M.3
  • 85
    • 0024215635 scopus 로고
    • Neurotensin and the mesocorticolimbic dopamine system
    • 1988
    • Bissette G, Nemeroff CB (1988). Neurotensin and the mesocorticolimbic dopamine system. Ann NY Acad Sci 1988; 537:397-404.
    • (1988) Ann NY Acad Sci , vol.537 , pp. 397-404
    • Bissette, G.1    Nemeroff, C.B.2
  • 86
    • 0024338054 scopus 로고
    • Pathologival changes induced in cerebrocortical neurons by phencyclidine and related drugs
    • Olney JW, Labruyere J, Price MT. Pathologival changes induced in cerebrocortical neurons by phencyclidine and related drugs. Science 1989; 244:1360-1362.
    • (1989) Science , vol.244 , pp. 1360-1362
    • Olney, J.W.1    Labruyere, J.2    Price, M.T.3
  • 88
    • 0027401398 scopus 로고
    • CNS signal transduction in the pathophysiology and pharmacotherapy of affective disorders and schizophrenia
    • Hudson CJ, Young LT, Li PP, Warsh JJ. CNS signal transduction in the pathophysiology and pharmacotherapy of affective disorders and schizophrenia. Synapse 1993; 13:278-293.
    • (1993) Synapse , vol.13 , pp. 278-293
    • Hudson, C.J.1    Young, L.T.2    Li, P.P.3    Warsh, J.J.4
  • 89
    • 0015452885 scopus 로고
    • Sensorische Störungen bei Schizophrenien
    • Gross G, Huber G. Sensorische Störungen bei Schizophrenien. Arch Psychiatr Nervenkr 1972; 216:119-130.
    • (1972) Arch Psychiatr Nervenkr , vol.216 , pp. 119-130
    • Gross, G.1    Huber, G.2


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