Induction of apoptosis in mesothelioma cells by antisurvivin oligonucleotides

Molecular Cancer Therapeutics

Volumn 1, Issue 9, 2002, Pages 687-694

  Xia, Chunyao ^a   Xu, Zhidong ^a   Yuan, Xiaocheng ^a   Uematsu, Kazutsugu ^a   You, Liang ^a   Li, Kai ^a   Li, Li ^a   McCormick, Frank ^a   Jablons, David M ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; BIRC5 PROTEIN, HUMAN; CASP3 PROTEIN, HUMAN; CASPASE; CASPASE 3; COMPLEMENTARY DNA; LIPOCORTIN 5; MICROTUBULE ASSOCIATED PROTEIN; OLIGONUCLEOTIDE; PROTEIN BCL 2; TUMOR PROTEIN;

APOPTOSIS; ARTICLE; CELL CULTURE; CELL DIVISION; CELL SURVIVAL; DNA MICROARRAY; DOSE RESPONSE; DOWN REGULATION; FLOW CYTOMETRY; GENE THERAPY; GENETIC TRANSFECTION; GENETICS; HUMAN; MESOTHELIOMA; METABOLISM; PATHOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TIME; WESTERN BLOTTING;

ANNEXIN A5; APOPTOSIS; BLOTTING, WESTERN; CASPASE 3; CASPASES; CELL DIVISION; CELL SURVIVAL; DNA, COMPLEMENTARY; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; FLOW CYTOMETRY; GENE THERAPY; HUMANS; MESOTHELIOMA; MICROTUBULE-ASSOCIATED PROTEINS; NEOPLASM PROTEINS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OLIGONUCLEOTIDES; OLIGONUCLEOTIDES, ANTISENSE; PROTO-ONCOGENE PROTEINS C-BCL-2; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TIME FACTORS; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0036632964     PISSN: 15357163     EISSN: 15388514     Source Type: Journal    
DOI: None     Document Type: Article

References (32)

1. Ambrosini, G., Adida, C., and Altieri, D. C. A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma. Nat. Med., 3: 917-921, 1997. (Pubitemid 27353455)
2. Reed, J. C. The survivin saga goes in vivo. J. Clin. Investig., 108:965-969, 2001. (Pubitemid 32946070)
3. Deveraux, Q., and Reed, J. C. IAP family proteins: suppressors of apoptosis. Genes Dev., 13: 239-252, 1999. (Pubitemid 29095796)
4. Grossman, D., Kim, P. J., Blanc-Brude, O. P., Brash, D. E., Tognin, S., Marchisio, P. C., and Altieri, D. C. Transgenic expression of survivin in keratinocytes counteracts UVB-induced apoptosis and cooperates with loss of p53. J. Clin. Investig., 108: 991-999, 2001. (Pubitemid 32946073)
5. Ambrosini, G., Adida, C., Sirugo, G., and Altieri, D., Induction of apoptosis and inhibition of cell proliferation by survivin gene targeting. J. Biol. Chem., 18: 11177-11182, 1998. (Pubitemid 28204967)
6. + T effector cells by dendritic cells pulsed with protein of selected peptides. Cancer Res., 60: 4845-4849, 2000.
7. Li, F., Ambrosini, G., Chu, E. Y., Plescia, J., Tognin, S., Marchisio, P. C., and Altieri, D. C. Control of apoptosis and mitotic spindle checkpoint by survivin. Nature (Lond.), 396: 580-584, 1998. (Pubitemid 28563719)
8. Grossman, D., McNiff, J. M., Li, F., and Altieri, D. C. Expression of the apoptosis inhibitor, survivin, in nonmelanoma skin cancer and gene targeting in a keratinocyte cell line. Lab. Investig., 79: 1121-1126, 1999. (Pubitemid 29444543)
9. Chen, J., Wu, W., Tahir, S. K., Kroeger, P. E., Robenberg, S. H., Cowsert, L. M., Bennett, F., Krajewski, S., Krajewska, M., Welsh, K., Reed, J. C., and Ng, S. C. Down-regulation of survivin by antisense oligonucleotides increases apoptosis, inhibits cytokinesis and anchorage-independent growth. Neoplasia, 2: 235-241, 2000. (Pubitemid 30346079)
10. Olie, R. A., Simoes-Wust, A. P., Baumann, B., Leech, S. H., Fabbro, D., Stahel, R. A., and Zangemeister-Wittke, U. A novel antisense oligonucleotide targeting survivin expression induces apoptosis and sensitizes lung cancer cells to chemotherapy. Cancer Res, 60: 2805-2809, 2000. (Pubitemid 30395796)
11. Mesri, M., Wall, N. R., Li, J., Kim, R. W., and Altieri, D. Cancer gene therapy using a survivin mutant adenovirus. J. Clin. Investig., 108: 981-990, 2001. (Pubitemid 32946072)
12. Bowman, R. V., Manning, L. S., Davis, M. R., and Robinson, B. W. S. Chemosensitivity and cytokine sensitivity of malignant mesothelioma. Cancer Chemother. Pharmacol, 28: 420-426, 1991.
13. Ong, S. T., and Vogelzang, N. J. Chemotherapy in malignant pleural mesothelioma: a review. J. Clin. Oncol., 14: 1007-1017, 1996. (Pubitemid 26085549)
14. Lechner, J. F., Tesfaigzi, J., and Gerwin, B. I. Oncogens and tumor-suppressor genes in mesothelioma: a synopsis. Environ. Health Perspect., 105 (Suppl. 5): 1061-1067, 1997.
15. Cheng, J. Q., Jhanwar, S. C., Klein, W. M., Bell, D. W., Lee, W. C., Altomare, D. A., Nobori, T., Olopade, O. I., Buckler, A. J., and Testa, J. R. p16 alterations and deletion mapping of 9p21-p22 in malignant mesothelioma. Cancer Res., 54: 5547-5551, 1997.
16. ARP gene transfer in human mesothelioma cells. J. Natl. Cancer Inst. (Bethesda), 92: 636-641, 2000.
17. Narasimhan, S. R., Yang, L., Gerwin, B. I., and Broaddus, V. C. Resistance of pleural mesothelioma cell lines to apoptosis: relation to expression of Bcl-2 and Bax. Am. J. Physiol., 275: L165-L171, 1998.
18. Tamm, I., Wang, Y., Sausville, E., Scudiero, D. A., Vigna, N., Oltersdorf, T., and Reed, J. C. IAP-family protein survivin inhibits caspase activity and apoptosis induced by Fas (CD95), Bax, caspases, and anticancer drugs. Cancer Res., 58: 5315-5320, 1998. (Pubitemid 28551107)
19. Nonzo, M., Rosell, R., Felip, E., Astudillo, J., Sanchez, J. J., Maestre, J., Martin, C., Font, A., Barnadas, A., and Abad, A. A novel anti-apoptosis gene: re-expression of survivin messenger RNA as a prognostic marker in non-small cell lung cancer. J. Clin. Oncol., 17: 2100-2104, 1999. (Pubitemid 29318841)
20. Kawasaki, H., Altieri, D. C., Lu, C-D., Toyoda, M., Tenjo, T., and Tanigawa, N. Inhibition of apotosis by survivin predicts shorter survival rates in colorectal cancer. Cancer Res., 58: 5071-5074, 1999. (Pubitemid 28521163)
21. Nakagawara, A. Molecular basis of spontaneous regression of neuroblastoma: role of neurotrophic signals and genetic abnormalities. Hum. Cell, 11: 115-124, 1998.
22. Li, F., Ackermann, E. J., Bennett, C. F., Rothermel, A. L., Plescia, J., Tognin, S., Villa, A., Marchisio, P. C., and Altieri, D. C. Pleiotropic cell-division defects and apoptosis induced by interference with survivin function. Nat. Cell. Biol., 1: 461-466, 1999. (Pubitemid 129503664)
23. Verdecia, M. A., Huang, H., Dutil, E., Kaiser, D. A., Hunter, T., and Noel, J. P. Structure of the human anti-apoptotic protein survivin reveals a dimeric arrangement. Nat. Struct. Biol., 7: 602-608, 2000. (Pubitemid 30445919)
24. Suzuki, A., Ito, T., Kawano, H., Hayashida, M., Hayasaki, Y., Tsutomi, Y., Akahane, K., Nakano, T., Miura, M., and Shiraki, K. Survivin initiates procaspase 3/p21 complex formation as a result of interaction with Cdk4 to resist Fas-mediated cell death. Oncogene, 19: 1346-1353, 2000. (Pubitemid 30160627)
25. Metcalf, R. A., Welsh, J. A., Bennett, W. P., Seddon, M. B., Lehman, T. A., Pelin, K., Linnainmaa, K., Tammilehto, L., Mattson, K., and Gerwin, B. I. p53 and Kirsten-ras mutations in human mesothelioma cell lines. Cancer Res., 52: 2610-2615, 1992.
26. Mor, O., Yaron, P., Huszar, M., Yellin, A., Jakobovitz, O., Brok-Simoni, F., Rechavi, G., and Reichert, N. Absence of p53 mutations in malignant mesotheliomas. Am. J. Respir. Cell Mol. Biol., 16: 9-13, 1997. (Pubitemid 127497429)
27. Reed, J. C. Bcl-2 and the regulation of programmed cell death. J. Cell Biol., 124: 1-6, 1994. (Pubitemid 24054605)
28. Jiang, S. X, Kameya, T., Sato, Y., Yanase, N., Yoshura, H., and Kodama, T. Bcl-2 protein expression in lung cancer and close correlation with neuroendocrine differentiation. Am. J. Pathol., 148: 837-846, 1996. (Pubitemid 126660675)
29. McDonnell, T. J., Troncoso, P., Brisbay, S. M., Logothetis, C., Chung, L. W. K., Hsieh, J-T., Tu, S. M., and Campbell, M. L. Expression of the proto-oncogene bcl-2 in the prostate and its association with emergence of androgen-independent prostate cancer. Cancer Res, 52: 6940-6944, 1992. (Pubitemid 23006303)
30. Silvestrini, R., Benini, E., Veneroni, S., Daidone, M. G., Tomasic, G., Squicciarini, P., and Salvadori, B. p53 and bcl-2 expression correlates with clinical outcome in a series of node-positive breast cancer patients. J. Clin. Oncol., 14: 1604-1610, 1966.
31. Lu, C-D., Altieri, C., and Tanigawa, N. Expression of a novel antiapoptosis gene, survivin, correlated with tumor cell apoptosis and p53 accumulation in gastric carcinomas. Cancer Res., 58: 1808-1812, 1998. (Pubitemid 28217451)
32. Jiang, X., Wilford, C., Duensing, S., Munger, K., Jones, G., and Jones, D. Participation of survivin in mitotic and apoptotic activities of normal and tumor-derived cells. J. Cell. Biochem., 83: 342-354, 2001. (Pubitemid 32896603)