AP20187-mediated activation of a chimeric insulin receptor results in insulin-like actions in skeletal muscle and liver of diabetic mice

Human Gene Therapy

Volumn 18, Issue 2, 2007, Pages 106-117

  Cotugno, Gabriella ^a,b   Formisano, Pietro ^c   Giacco, Ferdinando ^c   Colella, Pasqualina ^a   Beguinot, Francesco ^c   Auricchio, Alberto ^a,c  

^a TELETHON INSTITUTE OF GENETICS AND MEDICINE TIGEM   (Italy)

^b European School of Molecular Medicine SEMM   (Italy)

^c UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AP 20187; CHIMERIC PROTEIN; GENE PRODUCT; GLUCOSE; GLYCOGEN; HUMAN INSULIN; INSULIN; INSULIN RECEPTOR; LIGAND; PARVOVIRUS VECTOR; PROTEIN LFV2IRE; RECOMBINANT RECEPTOR; TYROSINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; DRUG ACTIVITY; DRUG RECEPTOR BINDING; GENE; GLUCOSE HOMEOSTASIS; GLUCOSE TRANSPORT; GLYCOGEN LIVER LEVEL; HORMONE ACTION; HORMONE RECEPTOR INTERACTION; HUMAN; INSULIN BINDING; LIVER; MCK GENE; MOUSE; NONHUMAN; NONOBESE DIABETIC MOUSE; PROTEIN PHOSPHORYLATION; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; VIRAL GENE DELIVERY SYSTEM;

ANIMALS; DEPENDOVIRUS; GENETIC VECTORS; GLUCOSE; GLYCOGEN; HUMANS; INSULIN; LIVER; MICE; MICE, INBRED NOD; MUSCLE, SKELETAL; PHOSPHOTYROSINE; RECEPTOR, INSULIN; RECOMBINANT FUSION PROTEINS; TACROLIMUS; TRANSDUCTION, GENETIC;

ANIMALIA; MUS;

EID: 33947433991     PISSN: 10430342     EISSN: None     Source Type: Journal    
DOI: 10.1089/hum.2006.116     Document Type: Article

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