Substrate tolerance of module 6 of the epothilone synthetase

Biochemistry

Volumn 46, Issue 11, 2007, Pages 3385-3393

  Tse, Martha Lovato ^a,c   Watts, R Edward ^a,d   Khosla, Chaitan ^a,b  

^a STANFORD UNIVERSITY   (United States)

^b Stanford University   (United States)

^c GENENTECH INC   (United States)

^d VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPOTHILONE SYNTHETASE; POLYKETIDE SYNTHASE; POLYKETIDES; SUBSTRATE TOLERANCE;

BIOSYNTHESIS; ESCHERICHIA COLI; KETONES; ONTOLOGY;

ENZYMES;

ACYL COENZYME A; EPOTHILONE C; EPOTHILONE D; EPOTHILONE DERIVATIVE; EPOTHILONE SYNTHETASE; MERCAPTAMINE; N ACETYLCYSTEAMINE; NATURAL PRODUCT; PACLITAXEL; POLYKETIDE SYNTHASE; SYNTHETASE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME SUBSTRATE COMPLEX; ESCHERICHIA COLI; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PURIFICATION;

ELECTROPHORESIS, POLYACRYLAMIDE GEL; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; MYXOCOCCALES; POLYKETIDE SYNTHASES; PROTEIN SUBUNITS; SUBSTRATE SPECIFICITY;

ESCHERICHIA COLI;

EID: 33947376470     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0616448     Document Type: Article

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