Binding of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) to protein- and low molecular weight thiols and its role in ring hydroxylation

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 376, Issue 1-2, 1997, Pages 7-12

  Alexander, Jan ^a   Reistad, Ragnhild ^a,b   Frandsen, Henrik ^c   Grivas, Spiros ^d  

^a NORWEGIAN INSTITUTE OF PUBLIC HEALTH   (Norway)

^b SIFO National Inst Consumer Res   (Norway)

^c National Food Agency of Denmark   (Denmark)

^d SWEDISH UNIVERSITY OF AGRICULTURAL SCIENCES   (Sweden)

Author keywords

2 Amino 1 methyl 6 phenylimidazo 4,5 b pyridine; 5 hydroxy PhIP; Glutathione; PhIP; PhIP glutathione conjugate; Protein binding; Thiol

Indexed keywords

2 AMINO 1 METHYL 6 PHENYLIMIDAZO[4,5 B]PYRIDINE; GLUTATHIONE; THIOL DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONJUGATE; CONTROLLED STUDY; HYDROXYLATION; LIVER CELL; METABOLITE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; RAT;

ANIMALS; GLUTATHIONE; HYDROXYLATION; IMIDAZOLES; LIVER; OXIDATION-REDUCTION; PROTEINS; RATS; SULFHYDRYL COMPOUNDS;

ANIMALIA;

EID: 0030914840     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0027-5107(97)00019-5     Document Type: Article

References (19)

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