Cytotoxic thiol alkylators

Mini-Reviews in Medicinal Chemistry

Volumn 7, Issue 2, 2007, Pages 131-139

  Pati, Hari N ^a   Das, Umashankar ^a   Sharma, Rajendra K ^b   Dimmock, Jonathan R ^a  

^a UNIVERSITY OF SASKATCHEWAN   (Canada)

^b UNIVERSITY OF SASKATCHEWAN   (Canada)

Author keywords

, unsaturated ketones; amethylene lactones; Alkylating agents; Azines; Benzoacronycine; Drug resistance; Imexon; Isothiocyanates; Thiols; Tumour sensitization

Indexed keywords

ALKYLATING AGENT; BENZIMIDAZOLE DERIVATIVE; CARMUSTINE; CHALCONE DERIVATIVE; CHLORAMBUCIL; CISPLATIN; CYCLOPHOSPHAMIDE; CYTOTOXIC AGENT; DOXORUBICIN; DRUG METABOLITE; ETACRYNIC ACID; ETOPOSIDE; GLUTATHIONE; GLUTATHIONE TRANSFERASE; GLYCOGEN SYNTHASE; GLYOXALASE; HELENALIN; IMEXON; ISOTHIOCYANIC ACID DERIVATIVE; LONIDAMINE; MANNICH BASE; MELPHALAN; MITOMYCIN A; MITOMYCIN C; PARACETAMOL; PIPERIDONE DERIVATIVE; POLYCYCLIC ENONE; REACTIVE OXYGEN METABOLITE; THIOL DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG; ANTINEOPLASTIC AGENT; CYCLOHEXENE DERIVATIVE;

ACETYLATION; ALKYLATION; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CANCER PREVENTION; CANCER RESISTANCE; CELL DEATH; COMBINATION CHEMOTHERAPY; CONCENTRATION RESPONSE; CYTOTOXICITY; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; DRUG STRUCTURE; DRUG SYNTHESIS; EHRLICH ASCITES TUMOR; ENZYME INHIBITION; HUMAN; LEUKEMIA P 388; MONOTHERAPY; NONHUMAN; OXIDATIVE STRESS; ANIMAL; CHEMISTRY; CLASSIFICATION; DRUG RESISTANCE; HYDROGEN BOND; REVIEW;

ALKYLATING AGENTS; ANIMALS; ANTINEOPLASTIC AGENTS; CYCLOHEXENES; DRUG RESISTANCE; HUMANS; HYDROGEN BONDING; SULFHYDRYL COMPOUNDS;

EID: 33847792559     PISSN: 13895575     EISSN: None     Source Type: Journal    
DOI: 10.2174/138955707779802642     Document Type: Article

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