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Volumn 24, Issue 3, 2001, Pages 303-306
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Costunolide induces apoptosis by ROS-mediated mitochondrial permeability transition and cytochrome C release
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Author keywords
Apoptosis; Costunolide; Cytochrome c; Mitochondria; Permeability transition; ROS
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Indexed keywords
ACETYLCYSTEINE;
ANTIOXIDANT;
COSTUNOLIDE;
CYCLOSPORIN A;
CYTOCHROME C;
REACTIVE OXYGEN METABOLITE;
SAUSSUREA LAPPA EXTRACT;
ANIMAL CELL;
ANIMAL TISSUE;
ANTINEOPLASTIC ACTIVITY;
APOPTOSIS;
ARTICLE;
CELL DEATH;
CELL STRAIN HL 60;
CHINESE HERB;
CHINESE MEDICINE;
CONTROLLED STUDY;
CYTOSOL;
DRUG EFFECT;
DRUG INHIBITION;
DRUG ISOLATION;
DRUG POTENCY;
ENZYME RELEASE;
HUMAN;
HUMAN CELL;
LEUKEMIA CELL;
MEDICINAL PLANT;
MEMBRANE PERMEABILITY;
MEMBRANE POTENTIAL;
MITOCHONDRIAL MEMBRANE;
NONHUMAN;
PLANT;
PLANT ROOT;
RAT;
SAUSSUREA LAPPA CLARKS;
ANIMALS;
ANTINEOPLASTIC AGENTS, PHYTOGENIC;
APOPTOSIS;
BLOTTING, WESTERN;
CASPASES;
CELL FRACTIONATION;
CYTOCHROME C GROUP;
DRUG SCREENING ASSAYS, ANTITUMOR;
ENZYME ACTIVATION;
HUMANS;
MEMBRANE POTENTIALS;
MITOCHONDRIA;
PERMEABILITY;
RATS;
REACTIVE OXYGEN SPECIES;
SESQUITERPENES;
TUMOR CELLS, CULTURED;
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EID: 0035080282
PISSN: 09186158
EISSN: None
Source Type: Journal
DOI: 10.1248/bpb.24.303 Document Type: Article |
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Times cited : (122)
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References (27)
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