Lipid Stress at Play: Mechanosensitivity of Voltage-Gated Channels

Current Topics in Membranes

Volumn 59, Issue , 2007, Pages 297-338

  Morris, Catherine E ^a   Juranka, Peter F ^a  

^a OTTAWA HOSPITAL RESEARCH INSTITUTE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 33847768020     PISSN: 10635823     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S1063-5823(06)59011-8     Document Type: Chapter

References (143)

1. Amano S., Ishikawa T., and Nakayama K. Facilitation of L-type Ca2+ currents by fluid flow in rabbit cerebral artery myocytes. J. Pharmacol. Sci. 98 (2005) 425-429
2. Barbuti A., Gravante B., Riolfo M., Milanesi R., Terragni B., and DiFrancesco D. Localization of pacemaker channels in lipid rafts regulates channel kinetics. Circ. Res. 94 (2004) 1325-1331
3. Bartucci R., Gambacorta A., Gliozzi A., Marsh D., and Sportelli L. Bipolar tetraether lipids: Chain flexibility and membrane polarity gradients from spin-label electron spin resonance. Biochemistry 44 (2005) 15017-15023
4. Baumgart T., Hess S.T., and Webb W.W. Imaging coexisting fluid domains in biomembrane models coupling curvature and line tension. Nature 425 (2003) 821-824
5. Belus A., and White E. Streptomycin and intracel, lular calcium modulate the response of single guinea-pig ventricular myocytes to axial stretch. J. Physiol. 546 (2003) 501-509
6. Ben-Tabou De-Leon S., Blotnick E., and Nussinovitch I. Effects of osmotic swelling on voltage-gated calcium channel currents in rat anterior pituitary cells. Am. J. Physiol. Cell Physiol. 285 (2003) C840-C852
7. Ben-Tabou De-Leon S., Ben-Zeev G., and Nussinovitch I. Effects of osmotic shrinkage on voltage-gated Ca2+ channel currents in rat anterior pituitary cells. Am. J. Physiol. Cell Physiol. 290 (2006) C222-C232
8. Bock J., Szabo I., Gamper N., Adams C., and Gulbins E. Ceramide inhibits the potassium channel Kv1. 3 by the formation of membrane platforms. Biochem. Biophys. Res. Commun. 305 (2003) 890-897
9. Brauchi S., Orio P., and Latorre R. Clues to understanding cold sensation: Thermodynamics and electrophysiological analysis of the cold receptor TRPM8. Proc. Natl. Acad. Sci. USA 101 (2004) 15494-15499
10. Calabrese B., Tabarean I.V., Juranka P., and Morris C.E. Mechanosensitivity of N-type calcium channel currents. Biophys. J. 83 (2002) 2560-2574
11. Calloe K., Elmedyb P., Olesen S.P., Jorgensen N.K., and Grunnet M. Hypoosmotic cell swelling as a novel mechanism for modulation of cloned HCN2 channels. Biophys. J. 89 (2005) 2159-2169
12. Camara A.K., Begic Z., Kwok W.M., and Bosnjak Z.J. Differential modulation of the cardiac L- and T-type calcium channel currents by isoflurane. Anesthesiology 95 (2001) 515-524
13. Cantor R.S. The lateral pressure profile in membranes: A physical mechanism of general anesthesia. Biochemistry 36 (1997) 2339-2344
14. Cantor R.S. Lipid composition and the lateral pressure profile in bilayers. Biophys. J. 76 (1999) 2625-2639
15. Chang H.M., Reitstetter R., Mason R.P., and Gruener R. Attenuation of channel kinetics and conductance by cholesterol: An interpretation using structural stress as a unifying concept. J. Membr. Biol. 143 (1995) 51-63
16. Chemin J., Monteil A., Perez-Reyes E., Nargeot J., and Lory P. Direct inhibition of T-type calcium channels by the endogenous cannabinoid anandamide. EMBO J. 20 (2001) 7033-7040
17. Chen X., Sirois J.E., Lei Q., Talley E.M., Lynch III C., and Bayliss D.A. HCN subunit-specific and cAMP-modulated effects of anesthetics on neuronal pacemaker currents. J. Neurosci. 25 (2005) 5803-5814
18. Chu B., and Treistman S.N. Modulation of two cloned potassium channels by 1-alkanols demonstrates different cutoffs. Alcohol Clin. Exp. Res. 21 (1997) 1103-1107
19. Chu B., Dopico A.M., Lemos J.R., and Treistman S.N. Ethanol potentiation of calcium-activated potassium channels reconstituted into planar lipid bilayers. Mol. Pharmacol. 54 (1998) 397-406
20. Clapham D.E. TRP channels as cellular sensors. Nature 426 (2003) 517-524
21. Clarke A.L., Petrou S., Walsh Jr. J.V., and Singer J.J. Site of action of fatty acids and other charged lipids on BKCa channels from arterial smooth muscle cells. Am. J. Physiol. Cell Physiol. 284 (2003) C607-C619
22. Conti F., Inoue I., Kukita F., and Stuhmer W. Pressure dependence of sodium gating currents in the squid giant axon. Eur. Biophys. J. 11 (1984) 137-147
23. Correa A.M. Gating kinetics of Shaker K+ channels are differentially modified by general anesthetics. Am. J. Physiol. 275 (1998) C1009-C1021
24. Covarrubias M., and Rubin E. Ethanol selectively blocks a noninactivating K+ current expressed in Xenopus oocytes. Proc. Natl. Acad. Sci. USA 90 (1993) 6957-6960
25. Crowley J.J., Treistman S.N., and Dopico A.M. Cholesterol antagonizes ethanol potentiation of human brain BKCa channels reconstituted into phospholipid bilayers. Mol. Pharmacol. 64 (2003) 365-372
26. Cuello L.G., Cortes D.M., and Perozo E. Molecular architecture of the KvAP voltage-dependent K+ channel in a lipid bilayer. Science 306 (2004) 491-495
27. Czub J., and Baginski M. Comparative molecular dynamics study of lipid membranes containing cholesterol and ergosterol. Biophys. J. 90 (2006) 2368-2382
28. Dan N., and Safran S.A. Effect of lipid characteristics on the structure of transmembrane proteins. Biophys. J. 75 (1998) 1410-1414
29. Davies D.L., Crawford D.K., Trudell J.R., Mihic S.J., and Alkana R.L. Multiple sites of ethanol action in alpha1 and alpha2 glycine receptors suggested by sensitivity to pressure antagonism. J. Neurochem. 89 (2004) 1175-1185
30. Devaux P.F., and Morris R. Transmembrane asymmetry and lateral domains in biological membranes. Traffic 5 (2004) 241-246
31. Dong X.X., and Iwasa K.H. Tension sensitivity of prestin: Comparison with the membrane motor in outer hair cells. Biophys. J. 86 (2004) 1201-1208
32. Dopico A.M., Kirber M.T., Singer J.J., and Walsh Jr. J.V. Membrane stretch directly activates large conductance Ca(2+)-activated K+ channels in mesenteric artery smooth muscle cells. Am. J. Hypertens. 7 (1994) 82-89
33. Dulhunty A.F., and Franzini-Armstrong C. The relative contributions of the folds and caveolae to the surface membrane of frog skeletal muscle fibres at different sarcomere lengths. J. Physiol. 250 (1975) 513-539
34. Elinder F., and Arhem P. Effects of gadolinium on ion channels in the myelinated axon of Xenopus laevis: Four sites of action. Biophys. J. 67 (1994) 71-83
35. Etzion Y., and Grossman Y. Pressure-induced depression of synaptic transmission in the cerebellar parallel fibre synapse involves suppression of presynaptic N-type Ca2+ channels. Eur. J. Neurosci. 12 (2000) 4007-4016
36. Feller S.E., Brown C.A., Nizza D.T., and Gawrisch K. Nuclear overhauser enhancement spectroscopy cross-relaxation rates and ethanol distribution across membranes. Biophys. J. 82 (2002) 1396-1404
37. Fisyunov A., Tsintsadze V., Min R., Burnashev N., and Lozovaya N.A. Cannabinoids modulate the P-type high voltage-activated calcium currents in Purkinje neurons. J. Neurophysiol. 96 (2006) 1267-1277
38. Folco E.J., Liu G.X., and Koren G. Caveolin-3 and SAP97 form a scaffolding protein complex that regulates the voltage-gated potassium channel Kv1. 5. Am. J. Physiol. Heart Circ. Physiol. 287 (2004) H681-H690
39. Franco-Obregon A., and Lansman J.B. Changes in mechanosensitive channel gating following mechanical stimulation in skeletal muscle myotubes from the mdx mouse. J. Physiol. 539 (2002) 391-407
40. Gaus K., Zech T., and Harder T. Visualizing membrane microdomains by Laurdan 2-photon microscopy. Mol. Membr. Biol. 23 (2006) 41-48
41. Gill C.H., Randall A., Bates S.A., Hill K., Owen D., Larkman P.M., Cairns W., Yusaf S.P., Murdock P.R., Strijbos P.J., Powell A.J., Benham C.D., et al. Characterization of the human HCN1 channel and its inhibition by capsazepine. Br. J. Pharmacol. 143 (2004) 411-421
42. Grabner M., Dirksen R.T., and Beam K.G. Tagging with green fluorescent protein reveals a distinct subcellular distribution of L-type and non-L-type Ca2+ channels expressed in dysgenic myotubes. Proc. Natl. Acad. Sci. USA 95 (1998) 1903-1908
43. Grunnet M., Jespersen T., MacAulay N., Jorgensen N.K., Schmitt N., Pongs O., Olesen S.P., and Klaerke D.A. KCNQ1 channels sense small changes in cell volume. J. Physiol. 549 (2003) 419-427
44. Gu C.X., Juranka P.F., and Morris C.E. Stretch-activation and stretch-inactivation of Shaker-IR, a voltage-gated K+ channel. Biophys. J. 80 (2001) 2678-2693
45. Guharay F., and Sachs F. Stretch-activated single ion channel currents in tissue-cultured embryonic chick skeletal muscle. J. Physiol. 352 (1984) 685-701
46. Guharay F., and Sachs F. Mechanotransducer ion channels in chick skeletal muscle: The effects of extracellular pH. J. Physiol. 363 (1985) 119-134
47. Guizy M., Arias C., David M., Gonzalez T., and Valenzuela C. {Omega}-3 and {omega}-6 polyunsaturated fatty acids block HERG channels. Am. J. Physiol. Cell Physiol. 289 (2005) C1251-C1260
48. Gullingsrud J., and Schulten K. Lipid bilayer pressure profiles and mechanosensitive channel gating. Biophys. J. 86 (2004) 3496-3509
49. Hajdu P., Varga Z., Pieri C., Panyi G., and Gaspar Jr. R. Cholesterol modifies the gating of Kv1. 3 in human T lymphocytes. Pflugers Arch. 445 (2003) 674-682
50. Harris T., Shahidullah M., Ellingson J.S., and Covarrubias M. General anesthetic action at an internal protein site involving the S4-S5 cytoplasmic loop of a neuronal K(+) channel. J. Biol. Chem. 275 (2000) 4928-4936
51. Hisada T., Walsh J.V.J., and Singer J.J. Stretch-inactivated cationic channels in single smooth muscle cells. Pflugers Arch. 422 (1993) 393-396
52. Hu Y.M., Zhang Z., Gao R.B., and Xu Y.Q. Effect of lysophosphatidylcholine on the pacemaker current I(f) of sheep cardiac Purkinje fibers in ischemia-like condition. Sheng Li Xue Bao 49 (1997) 513-520
53. Hurwitz C.G., Hu V.Y., and Segal A.S. A mechanogated nonselective cation channel in proximal tubule that is ATP sensitive. Am. J. Physiol. Renal Physiol. 283 (2002) F93-F104
54. Iwata A., Stys P.K., Wolf J.A., Chen X.H., Taylor A.G., Meaney D.F., and Smith D.H. Traumatic axonal injury induces proteolytic cleavage of the voltage-gated sodium channels modulated by tetrodotoxin and protease inhibitors. J. Neurosci. 24 (2004) 4605-4613
55. Kahya N., and Schwille P. Fluorescence correlation studies of lipid domains in model membranes. Mol. Membr. Biol. 23 (2006) 29-39
56. Kamatchi G.L., Durieux M.E., and Lynch III C. Differential sensitivity of expressed L-type calcium channels and muscarinic M(1) receptors to volatile anesthetics in Xenopus oocytes. J. Pharmacol. Exp. Ther. 297 (2001) 981-990
57. Kendig J.J. Nitrogen narcosis and pressure reversal of anesthetic effects in node of Ranvier. Am. J. Physiol. 246 (1984) C91-C95
58. Kirber M.T., Walsh Jr. J.V., and Singer J.J. Stretch-activated ion channels in smooth muscle: A mechanism for the initiation of stretch-induced contraction. Pflugers Arch. 412 (1988) 339-345
59. Kubota T., Horie M., Takano M., Yoshida H., Otani H., and Sasayama S. Role of KCNQ1 in the cell swelling-induced enhancement of the slowly activating delayed rectifier K(+) current. Jpn. J. Physiol. 52 (2002) 31-39
60. Kung C. A possible unifying principle for mechanosensation. Nature 436 (2005) 647-654
61. Laitko U., and Morris C.E. Membrane tension accelerates rate-limiting voltage-dependent activation and slow inactivation steps in a Shaker channel. J. Gen. Physiol. 123 (2004) 135-154
62. Laitko U., Juranka P.F., and Morris C.E. Membrane stretch slows the concerted step prior to opening in a Kv channel. J. Gen. Physiol. 127 (2006) 687-701
63. Langton P.D. Calcium channel currents recorded from isolated myocytes of rat basilar artery are stretch sensitive. J. Physiol. 471 (1993) 1-11
64. Ledwell J.L., and Aldrich R.W. Mutations in the S4 region isolate the final voltage-dependent cooperative step in potassium channel activation. J. Gen. Physiol. 113 (1999) 389-414
65. Lee S.Y., Lee A., Chen J., and MacKinnon R. Structure of the KvAP voltage-dependent K+ channel and its dependence on the lipid membrane. Proc. Natl. Acad. Sci. USA 102 (2005) 15441-15446
66. Levitan I., Helmke B.P., and Davies P.F. A chamber to permit invasive manipulation of adherent cells in laminar flow with minimal disturbance of the flow field. Ann. Biomed. Eng. 28 (2000) 1184-1193
67. Li J., and Correa A.M. Kinetic modulation of HERG potassium channels by the volatile anesthetic halothane. Anesthesiology 97 (2002) 921-930
68. Lin W., Latiko U., Juranka P.F., and Morris C.E. Dual stretch responses of mHCN2 pacemaker channels: Accelerated activation, accelerated deactivation. Biophys. J. (2006) [Epub ahead of print 2006 Dec 1]
69. Liu L., Zhu W., Zhang Z.S., Yang T., Grant A., Oxford G., and Simon S.A. Nicotine inhibits voltage-dependent sodium channels and sensitizes vanilloid receptors. J. Neurophysiol. 91 (2004) 1482-1491
70. Long S.B., Campbell E.B., and Mackinnon R. Crystal structure of a mammalian voltage-dependent Shaker family K+ channel. Science 309 (2005) 897-903
71. Long S.B., Campbell E.B., and Mackinnon R. Voltage sensor of Kv1. 2: Structural basis of electromechanical coupling. Science 309 (2005) 903-908
72. Lundbaek J.A., Birn P., Hansen A.J., Sogaard R., Nielsen C., Girshman J., Bruno M.J., Tape S.E., Egebjerg J., Greathouse D.V., Mattice G.L., Koeppe II R.E., et al. Regulation of sodium channel function by bilayer elasticity: The importance of hydrophobic coupling. Effects of micelle-forming amphiphiles and cholesterol. J. Gen. Physiol. 123 (2004) 599-621
73. Lundbaek J.A., Birn P., Tape S.E., Toombes G.E., Sogaard R., Koeppe II R.E., Gruner S.M., Hansen A.J., and Andersen O.S. Capsaicin regulates voltage-dependent sodium channels by altering lipid bilayer elasticity. Mol. Pharmacol. 68 (2005) 680-689
74. Ly H.V., and Longo M.L. The influence of short-chain alcohols on interfacial tension, mechanical properties, area/molecule, and permeability of fluid lipid bilayers. Biophys. J. 87 (2004) 1013-1033
75. Lyford G.L., Strege P.R., Shepard A., Ou Y., Ermilov L., Miller S.M., Gibbons S.J., Rae J.L., Szurszewski J.H., and Farrugia G. α(1C) (Ca(V)1. 2) L-type calcium channel mediates mechanosensitive calcium regulation. Am. J. Physiol. Cell Physiol. 283 (2002) C1001-C1008
76. Macdonald A.G. Ion channels under high pressure. Comp. Biochem. Physiol. A Mol. Integr. Physiol. 131 (2002) 587-593
77. Mannikko R., Elinder F., and Larsson H.P. Voltage-sensing mechanism is conserved among ion channels gated by opposite voltages. Nature 419 (2002) 837-841
78. Maroto R., and Hamill O.P. Brefeldin A block of integrin-dependent mechanosensitive ATP release from Xenopus oocytes reveals a novel mechanism of mechanotransduction. J. Biol. Chem. 276 (2001) 23867-23872
79. Maroto R., Raso A., Wood T.G., Kurosky A., Martinac. B., and Hamill O.P. TRPC1 forms the stretch-activated cation channel in vertebrate cells. Nat. Cell Biol. 7 (2005) 179-185
80. McNaughton N.C., Green P.J., and Randall A.D. Inhibition of human alpha1E subunit-mediated Ca2+ channels by the antipsychotic agent chlorpromazine. Acta Physiol. Scand. 173 (2001) 401-408
81. Meyer G.R., Gullingsrud J., Schulten K., and Martinac B. Molecular dynamics study of MscL interactions with a curved lipid bilayer. Biophys. J. 91 (2006) 1630-1637
82. Meyer R., and Heinemann S.H. Temperature and pressure dependence of Shaker K+ channel N- and C-type inactivation. Eur. Biophys. J. 26 (1997) 433-445
83. McEwen D.P., and Isom L.L. Heterophilic interactions of sodium channel beta1 subunits with axonal and glial cell adhesion molecules. J. Biol. Chem. 279 (2004) 52744-52752
84. Mitchell D.C., and Litman B.J. Effect of ethanol and osmotic stress on receptor conformation. Reduced water activity amplifies the effect of ethanol on metarhodopsin II formation. J. Biol. Chem. 275 (2000) 5355-5360
85. Mitchell D.C., Lawrence J.T., and Litman B.J. Primary alcohols modulate the activation of the G protein-coupled receptor rhodopsin by a lipid-mediated mechanism. J. Biol. Chem. 271 (1996) 19033-19036
86. Moran O., Tammaro P., Nizzari M., and Conti F. Functional properties of sodium channels do not depend on the cytoskeleton integrity. Biochem. Biophys. Res. Commun. 276 (2000) 204-209
87. Morris C.E. Mechanoprotection of the plasma membrane in neurons and other non-erythroid cells by the spectrin-based membrane skeleton. Cell Mol. Biol. Lett. 6 (2001) 703-720
88. Morris C.E., and Sigurdson W.J. Stretch-inactivated ion channels coexist with stretch-activated ion channels. Science 243 (1989) 807-809
89. Morris C.E., and Laitko U. The mechanosensitivity of voltage-gated channels may contribute to cardiac M.E.F. In: Kohl P., Franz M., and Sachs F. (Eds). "Cardiac Mechano-Electric Feedback and Arrhythmias: From Pipette to Patient" (2005), Saunders Philadelphia, Pennsylvania 33-41
90. Morris C.E., Juranka P.F., Lin W., Morris T.J., and Laitko U. Studying the mechanosensitivity of voltage-gated channels using oocyte patches. In: Liu X.J. (Ed). "Xenopus Protocols: Cell Biology and Signal Transduction". Methods Mol. Biol. 322 (2006) 315-329
91. Mozrzymas J.W., Teisseyre A., and Vittur F. Propofol blocks voltage-gated potassium channels in human T lymphocytes. Biochem. Pharmacol. 52 (1996) 843-849
92. Murata Y., Iwasaki H., Sasaki M., Inaba K., and Okamura Y. Phosphoinositide phosphatase activity coupled to an intrinsic voltage sensor. Nature 435 (2005) 1239-1243
93. Namba T., Ishii T.M., Ikeda M., Hisano T., Itoh T., Hirota K., Adelman J.P., and Fukuda K. Inhibition of the human intermediate conductance Ca(2+)-activated K(+) channel, hIK1, by volatile anesthetics. Eur. J. Pharmacol. 395 (2000) 95-101
94. Nicholson R.A., Liao C., Zheng J., David L.S., Coyne L., Errington A.C., Singh G., and Lees G. Sodium channel inhibition by anandamide and synthetic cannabimimetics in brain. Brain Res. 978 (2003) 194-204
95. Nilius B., Talavera K., Owsianik G., Prenen J., Droogmans G., and Voets T. Gating of TRP channels: A voltage connection?. J. Physiol. 567 (2005) 35-44
96. Niu S.L., Mitchell D.C., and Litman B. Manipulation of cholesterol levels in rod disk membranes by methyl-beta-cyclodextrin: Effects on receptor activation. J. Biol. Chem. 277 (2002) 20139-20145
97. Niu S.L., and Mitchell D.C. Effect of packing density on rhodopsin stability and function in polyunsaturated membranes. Biophys. J. 89 (2005) 1833-1840
98. Ogata N., and Narahashi T. Block of sodium channels by psychotropic drugs in single guinea-pig cardiac myocytes. Br. J. Pharmacol. 97 (1989) 905-913
99. Olcese R., Usai C., Maestrone E., and Nobile M. The general anesthetic propofol inhibits transmembrane calcium current in chick sensory neurons. Anesth. Analg. 78 (1994) 955-960
100. Okamoto T., Harnett M.T., and Morikawa H. Hyperpolarization-activated cation current (Ih) is an ethanol target in midbrain dopamine neurons of mice. J. Neurophysiol. 95 (2006) 619-626
101. Oliver D., Lien C.C., Soom M., Baukrowitz T., Jonas P., and Fakler B. Functional conversion between A-type and delayed rectifier K+ channels by membrane lipids. Science 304 (2004) 265-270
102. Ou X., Blount P., Hoffman R.J., and Kung C. One face of a transmembrane helix is crucial in mechanosensitive channel gating. Proc. Natl. Acad. Sci. USA 95 (1998) 11471-11475
103. Ouyang W., Wang G., and Hemmings Jr. H.C. Isoflurane and propofol inhibit voltage-gated sodium channels in isolated rat neurohypophysial nerve terminals. Mol. Pharmacol. 64 (2003) 373-381
104. Park J.B., Kim H.J., Ryu P.D., and Moczydlowski E. Effect of phosphatidylserine on unitary conductance and Ba2+ block of the BK Ca2+-activated K+ channel: Re-examination of the surface charge hypothesis. J. Gen. Physiol. 121 (2003) 375-397
105. Pascarel C., Brette F., and Le Guennec J.Y. Enhancement of the T-type calcium current by hyposmotic shock in isolated guinea-pig ventricular myocytes. J. Mol. Cell. Cardiol. 33 (2001) 1363-1369
106. Pathak M., Agarwal G., Kurtz L., Gandhi C.S., and Isacoff E.Y. A fluorescence scan to investigate the structural dynamics of the Shaker K+ channel (2006) Abstract #2268 Biophysical Society
107. Pawson L., and Bolanowski S.J. Voltage-gated sodium channels are present on both the neural and capsular structures of Pacinian corpuscles. Somatosens. Mot. Res. 19 (2002) 231-237
108. Pencer J., Nieh M.P., Harroun T.A., Krueger S., Adams C., and Katsaras J. Bilayer thickness and thermal response of dimyristoylphosphatidylcholine unilamellar vesicles containing cholesterol, ergosterol and lanosterol: A small-angle neutron scattering study. Biochim. Biophys. Acta 1720 (2005) 84-91
109. Piao L., Li Y., Li L., and Xu W.X. Increment of calcium-activated and delayed rectifier potassium current by hyposmotic swelling in gastric antral circular myocytes of guinea pig. Acta Pharmacol. Sin. 22 (2001) 566-572
110. Piao L., Ying Li H., Park C.K., Cho I.H., Piao Z.G., Jung S.J., Choi S.Y., Lee S.J., Park K., Kim J.S., and Oh S.B. Mechanosensitivity of voltage-gated K(+) currents in rat trigeminal ganglion neurons. J. Neurosci. Res. 83 (2006) 1373-1380
111. Poling J.S., Rogawski M.A., Salem Jr. N., and Vicini S. Anandamide, an endogenous cannabinoid, inhibits Shaker-related voltage-gated K+ channels. Neuropharmacology 35 (1996) 983-991
112. Ramsey I.S., Moran M.M., Chong J.A., and Clapham D.E. A voltage-gated proton-selective channel lacking the pore domain. Nature 440 (2006) 1213-1216
113. Riechmann L., Lavenir I., de Bono S., and Winter G. Folding and stability of a primitive protein. J. Mol. Biol. 348 (2005) 1261-1272
114. Rodriguez B.M., Sigg D., and Bezanilla F. Voltage gating of Shaker K+ channels. The effect of temperature on ionic and gating currents. J. Gen. Physiol. 112 (1998) 223-242
115. Sako Y., Nomura N., Uchida A., Ishida Y., Morii H., Koga Y., Hoaki T., and Maruyama T. Aeropyrum pernix gen. nov., sp. nov., a novel aerobic hyperthermophilic archaeon growing at temperatures up to 100 degrees C. Int. J. Syst. Bacteriol. 46 (1996) 1070-1077
116. Scarlata S., McBath H., and Haspel H.C. Effect of lipid packing on the conformational states of purified GLUT-1 hexose transporter. Biochemistry 34 (1995) 7703-7711
117. Shahidullah M., Harris T., Germann M.W., and Covarrubias M. Molecular features of an alcohol binding site in a neuronal potassium channel. Biochemistry 42 (2003) 11243-11252
118. Shcherbatko A., Ono F., Mandel G., and Brehm P. Voltage-dependent sodium channel function is regulated through membrane mechanics. Biophys. J. 77 (1999) 1945-1959
119. Shiraishi M., and Harris R.A. Effects of alcohols and anesthetics on recombinant voltage-gated Na+ channels. J. Pharmacol. Exp. Ther. 309 (2004) 987-994
120. Strege P.R., Holm A.N., Rich A., Miller S.M., Ou Y., Sarr M.G., and Farrugia G. Cytoskeletal modulation of sodium current in human jejunal circular smooth muscle cells. Am. J. Physiol. Cell Physiol. 284 (2003) C60-C66
121. Su Z., Martin R., Cox B.F., and Gintant G. Mesoridazine: An open-channel blocker of human ether-a-go-go-related gene K+ channel. J. Mol. Cell. Cardiol. 36 (2004) 151-160
122. Tabarean I.V., and Morris C.E. Membrane stretch accelerates activation and slow inactivation in Shaker channels with S3-S4 linker deletions. Biophys. J. 82 (2002) 2982-2994
123. Tabarean I.V., Juranka P., and Morris C.E. Membrane stretch affects gating modes of a skeletal muscle sodium channel. Biophys. J. 77 (1999) 758-774
124. Tanaka T., Tamba Y., Masum S.M., Yamashita Y., and Yamazaki M. La(3+) and Gd(3+) induce shape change of giant unilamellar vesicles of phosphatidylcholine. Biochim. Biophys. Acta 1564 (2002) 173-182
125. Teisseyre A., and Michalak K. The voltage- and time-dependent blocking effect of trifluoperazine on T lymphocyte Kv1.3 channels. Biochem. Pharmacol. 65 (2003) 551-561
126. Terakawa S., and Nakayama T. Are axoplasmic microtubules necessary for membrane excitation?. J. Membr. Biol. 85 (1985) 65-77
127. Tillman T.S., and Cascio M. Effects of membrane lipids on ion channel structure and function. Cell Biochem. Biophys. 38 (2003) 161-190
128. Thomas D., Wu K., Kathofer S., Katus H.A., Schoels W., Kiehn J., and Karle C.A. The antipsychotic drug chlorpromazine inhibits HERG potassium channels. Br. J. Pharmacol. 139 (2003) 567-574
129. Tombola F., Pathak M.M., and Isacoff E.Y. How far will you go to sense voltage?. Neuron 48 (2005) 719-725
130. Tombola F., Pathak M.M., and Isacoff E.Y. How does voltage open an ion channel?. Annu. Rev. Cell Dev. Biol. (2006) May 5 [Epub ahead of print]
131. Toselli M., Biella G., Taglietti V., Cazzaniga E., and Parenti M. Caveolin-1 expression and membrane cholesterol content modulate N-type calcium channel activity in NG108-15 cells. Biophys. J. 89 (2005) 2443-2457
132. Traub O., Ishida T., Ishida M., Tupper J.C., and Berk B.C. Shear stress-mediated extracellular signal-regulated kinase activation is regulated by sodium in endothelial cells. Potential role for a voltage-dependent sodium channel. J. Biol. Chem. 274 (1999) 20144-20150
133. Treistman S.N., and Wilson A. Alkanol effects on early potassium currents in Aplysia neurons depend on chain length. Proc. Natl. Acad. Sci. USA 84 (1987) 9299-9303
134. Van den Brink-van der Laan E., Chupin V., Killian J.A., and de Kruijff B. Small alcohols destabilize the KcsA tetramer via their effect on the membrane lateral pressure. Biochemistry 43 (2004) 5937-5942
135. Wallace C.H., Baczko I., Jones L., Fercho M., and Light P.E. Inhibition of cardiac voltage-gated sodium channels by grape polyphenols. Br. J. Pharmacol. 149 (2006) 657-665
136. Wang J., Wang H., Han H., Zhang Y., Yang B., Nattel S., and Wang Z. Phospholipid metabolite 1-palmitoyl-lysophosphatidylcholine enhances human ether-a-go-go-related gene (HERG) K(+) channel function. Circulation 104 (2001) 2645-2648
137. Wiggins P., and Phillips R. Membrane-protein interactions in mechanosensitive channels. Biophys. J. 88 (2005) 880-902
138. Wong W., and Schlichter L.C. Differential recruitment of Kv1. 4 and Kv4. 2 to lipid rafts by PSD-95. J. Biol. Chem. 279 (2004) 444-452
139. Xiao Y.F., Ma L., Wang S.Y., Josephson M.E., Wang G.K., Morgan J.P., and Leaf A. Potent block of inactivation-deficient Na+ channels by n-3 polyunsaturated fatty acids. Am. J. Physiol. Cell Physiol. 290 (2006) C362-C370
140. Xu W.X., Li Y., Wu L.R., and Li Z.L. Effects of different kinds of stretch on voltage-dependent calcium current in antrial circular smooth muscle cells of the guinea-pig. Sheng Li Xue Bao 52 (2000) 69-74
141. Yang X.C., and Sachs F. Block of stretch-activated ion channels in Xenopus oocytes by gadolinium and calcium ions. Science 243 (1989) 1068-1071
142. Yao X., McIntyre M.S., Lang D.G., Song I.H., Becherer J.D., and Hashim M.A. Propranolol inhibits the human ether-a-go-go-related gene potassium channels. Eur. J. Pharmacol. 519 (2005) 208-211
143. Ying S.W., Abbas S.Y., Harrison N.L., and Goldstein P.A. Propofol block of I(h) contributes to the suppression of neuronal excitability and rhythmic burst firing in thalamocortical neurons. Eur. J. Neurosci. 23 (2006) 465-480