Gating kinetics of Shaker K+ channels are differentially modified by general anesthetics

American Journal of Physiology - Cell Physiology

Volumn 275, Issue 4 44-4, 1998, Pages

  Correa, Ana M ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Chloroform; Halothane; Isoflurane; Volatile anesthetics; Xenopus oocytes

Indexed keywords

CHLOROFORM; HALOTHANE; ISOFLURANE; POTASSIUM CHANNEL;

ANIMAL CELL; ARTICLE; CHANNEL GATING; CONFORMATIONAL TRANSITION; DRUG EFFECT; DRUG PROTEIN BINDING; GENERAL ANESTHESIA; NONHUMAN; PRIORITY JOURNAL; XENOPUS;

EID: 0031753689     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.1998.275.4.c1009     Document Type: Article

References (31)

1. Bean, B. P., P. Shrager, and A. D. Goldstein. Modification of sodium and potassium channel gating kinetics by ether and halothane. J. Gen. Physiol. 77: 233-253, 1981.
2. + channels. II. The components of gating currents and a model of channel activation. Biophys. J. 66: 1011-1021, 1994.
3. Charlesworth, P., G. Pocock, and C. D. Richards. Calcium channel currents in bovine adrenal chromaffin cells and their modulation by anaesthetics. J. Physiol. (Lond.) 481: 543-553, 1994.
4. Correa, A. M. Gating and ionic currents of voltage-gated ionic channels exposed to general anesthetics (Abstract). Biophys. J. A439, 1994.
5. + conductance in hippocampus. Nature 389: 286-289, 1997.
6. Dilger, J. P. Basic pharmacology of inhalational anesthetic agents. In: The Pharmacological Basis of Anesthesiology, edited by T. A. Bowdle, A. Horita, and E. D. Kharasch. New York: Churchill Livingstone, 1994, chapt. 23, p. 497-521.
7. Elliot, J. R., and B. W. Urban. Integrative effects of general anesthetics: why nerve axons should not be ignored. Eur. J. Anaesthesiol. 12: 41-50, 1995.
8. + channels in dog cerebral arterial muscle cells. Anesthesiology 82: 479-490, 1995.
9. Fernandez, J. M., F. Bezanilla, and R. E. Taylor. Effect of chloroform on charge movement in the nerve membrane. Nature 297: 150-152, 1982.
10. Franks, N. P., and W. R. Lieb. Molecular and cellular mechanisms of general anaesthesia. Nature 367: 607-614, 1994.
11. Goldin, A. L. Maintenance of Xenopus laevis and oocyte injection. Methods Enzymol. 207: 266-279, 1992.
12. 3) pituitary cells. J. Neurosci. 11: 2226-2240, 1991.
13. + channel regulation of signal propagation in dendrites of hippocampal pyramidal neurons. Nature 387: 869-875, 1997.
14. Hoshi, T., W. N. Zagotta, and R. W. Aldrich. Shaker potassium channel gating. I. Transitions near the open state. J. Gen. Physiol. 103: 249-278, 1994.
15. Janoff, A. S., M. J. Pringle, and K. W. Miller. Correlation of general anesthetic potency with solubility in membranes. Biochim. Biophys. Acta 649: 125-128, 1981.
16. Kulkarni, R. S., L. J. Zorn, V. Anantharam, H. Bayley, and S. N. Treistman. Inhibitory effects of ketamine and halothane on recombinant potassium channels from mammalian brain. Anesthesiology 84: 900-909, 1996.
17. MacIver, M. B., and D. L. Tanelian. Volatile anesthetics excite mammalian nociceptor afferents recorded in vitro. Anesthesiology 72: 1022-1030, 1990.
18. Mihic, S. J., Q. Ye, M. J. Wick, V. V. Koltchine, M. D. Krasowski, S. E. Finn, M. P. Mascia, C. F. Valenzuela, K. K. Hanson, E. P. Greenblatt, R. A Harris, and N. L. Harrison. Sites of alcohol and volatile anaesthetic action on GABAA and glycine receptors. Nature 389: 385-389, 1997.
19. + channels with a pore blocking site studied with synthetic peptides. J. Gen. Physiol. 102: 949-975, 1993.
20. 2+ channel current in guinea-pig myocytes. J. Physiol. (Lond.) 494: 91-103, 1996.
21. + channels. Neuron 11: 353-358, 1993.
22. + channel: probing with temperature. Neuropharmacology 35: 775-785, 1996.
23. Stefani, E., and F. Bezanilla. The cut open oocyte voltage clamp technique. Methods Enzymol. 293: 300-318, 1998.
24. + channels. I. Ionic and gating currents. Biophys. J. 66: 996-1010, 1994.
25. Study, R. E. Isoflurane inhibits multiple voltage-gated calcium currents in hippocampal pyramidal neurons. Anesthesiology 81: 104-116, 1994.
26. Tinklenberg, J. A., I. S. Segal, G. Tianzhi, and M. Maze. Analysis of anesthetic action on potassium channels of the Shaker mutant of Drosophila. Ann. NY Acad. Sci. 625: 532-539, 1991.
27. Urban, B. W. Differential effects of gaseous and volatile anaesthetics on sodium and potassium channels. Br. J. Anaesth. 71: 25-38, 1993.
28. Urban, B. W., and D. A. Haydon. The actions of halogenated ethers on the ionic currents of the squid giant axon. Proc. R. Soc. Lond. B Biol. Sci. 231: 13-26, 1987.
29. + channels (Abstract). Anesthesiology 79: A383, 1993.
30. Winegar, B. D., D. F. Owen, C. S. Yost, J. R. Forsayeth, and E. Mayeri. Volatile general anesthetics produce hyperpolarization of Aplysia neurons by activation of a discrete population of baseline potassium channels. Anesthesiology 85: 889-900, 1996.
31. Zorn, L., R. Kulkarni, V. Anantharam, H. Bayley, and S. N. Treistman. Halothane acts on many potassium channels, including a minimal potassium channel. Neurosci. Lett. 161: 81-84, 1993.