Functional relevance of an enhanced expression of the Na+-Ca2+ exchanger in the failing human heart

Annals of the New York Academy of Sciences

Volumn 779, Issue , 1996, Pages 539-542

  Flesch, M ^a   Putz F ^a   Schwinger, R H G ^a   Bohm M ^a  

^a UNIVERSITY OF COLOGNE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; SODIUM ION;

CLINICAL ARTICLE; CONFERENCE PAPER; HEART FAILURE; HEART LEFT VENTRICLE; HEART MUSCLE; HUMAN; HUMAN TISSUE; SODIUM CALCIUM EXCHANGE;

EID: 0029932982     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1996.tb44832.x     Document Type: Article

References (10)

1. 2+ content in young spontaneously hypertensive rats. J. Cardiovasc. Pharmacol. 8(Suppl. 8): S130-S135.
2. 2+ transport activities in cardiac hypertrophy caused by pressure overload. Am. J. Physiol. 257: H349-H356.
3. 2+ exchanger in end-stage human heart failure. Circ. Res. 75: 443-453.
4. SCHWINGER, R. H. G., M. BÖHM, C. MITTMANN, K. LA ROSÉE & E. ERDMANN. 1991. Evidence for a sustained effectiveness of sodium-channel activator in failing human myocardium. J. Mol. Cell. Cardiol: 23: 461-471.
5. 2+ exchanger. Science 250: 562-565.
6. 2+ exchange protein. Biochim. Biophys. Acta. 945: 298-306.
7. BEUCKELMANN, D. J., M. NÄBAUER & E. ERDMANN. 1992. Intracellular calcium handling in isolated ventricular myocytes from patients with terminal heart failure. Circulation 85: 1046-1055.
8. BERS, D. M. 1987. Mechanisms contributing to the cardiac intropic effect of Na-pump inhibition and reduction of extracellular Na. J. Gen. Physiol. 90: 479-504.
9. LEVI, A. J., P. BROOKSBY & J. C. HANCOX 1993. A role for depolarisation induced calcium entry on the Na-Ca exchange in triggering intracellular calcium release and contraction in rat ventricular myocytes. Cardiovasc. Res. 27: 1677-1690.
10. 2+ exchanger in the rate dependent increase in contraction in guinea pig ventricular myocytes. J. Physiol. 482(3): 555-566.