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Volumn 100, Issue 6, 2007, Pages 1589-1598

Pyruvate modifies glycolytic and oxidative metabolism of rat embryonic spinal cord astrocyte cell lines and prevents their spontaneous transformation

Author keywords

Astrocytes; Mitochondria; Pyruvate; Spinal cord; Spontaneous transformation

Indexed keywords

GLUCOSE; LACTIC ACID; PYRUVIC ACID;

EID: 33847743111     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2006.04318.x     Document Type: Article
Times cited : (6)

References (43)
  • 1
    • 0031668862 scopus 로고    scopus 로고
    • Amyloid β protein inhibits cellular MTT reduction not by suppression of mitochondrial succinate dehydrogenase but by acceleration of MTT formazan exocytosis in cultured rat cortical astrocytes
    • Abe K. and Saito H. (1998) Amyloid β protein inhibits cellular MTT reduction not by suppression of mitochondrial succinate dehydrogenase but by acceleration of MTT formazan exocytosis in cultured rat cortical astrocytes. Neurosci. Res. 31, 295-305.
    • (1998) Neurosci. Res , vol.31 , pp. 295-305
    • Abe, K.1    Saito, H.2
  • 2
    • 0031835628 scopus 로고    scopus 로고
    • A rapid method for the isolation of metabolically active mitochondria from rat neurons and astrocytes in primary culture
    • Almeida A. and Medina J. M. (1998) A rapid method for the isolation of metabolically active mitochondria from rat neurons and astrocytes in primary culture. Brain Res. Brain Res. Protoc. 2, 209-214.
    • (1998) Brain Res. Brain Res. Protoc , vol.2 , pp. 209-214
    • Almeida, A.1    Medina, J.M.2
  • 3
    • 0038167009 scopus 로고    scopus 로고
    • Pyruvate protection against β-amyloid-induced neuronal death: Role of mitochondrial redox state
    • Alvarez G., Ramos M., Ruiz F., Satrustegui J. and Bogonez E. (2003) Pyruvate protection against β-amyloid-induced neuronal death: role of mitochondrial redox state. J. Neurosci. Res. 73, 260-269.
    • (2003) J. Neurosci. Res , vol.73 , pp. 260-269
    • Alvarez, G.1    Ramos, M.2    Ruiz, F.3    Satrustegui, J.4    Bogonez, E.5
  • 4
    • 0017277818 scopus 로고
    • Assay of proteins in the presence of interfering materials
    • Bensadoun A. and Weinstein D. (1976) Assay of proteins in the presence of interfering materials. Anal. Biochem. 70, 241-250.
    • (1976) Anal. Biochem , vol.70 , pp. 241-250
    • Bensadoun, A.1    Weinstein, D.2
  • 5
    • 0032478648 scopus 로고    scopus 로고
    • Is absence of pyruvate dehydrogenase complex in mitochondria a possible explanation of significant aerobic glycolysis by normal human leukocytes?
    • Biswas S., Ray M., Misra S., Dutta D. P. and Subhankar R. (1998) Is absence of pyruvate dehydrogenase complex in mitochondria a possible explanation of significant aerobic glycolysis by normal human leukocytes? FEBS Lett. 425, 411-414.
    • (1998) FEBS Lett , vol.425 , pp. 411-414
    • Biswas, S.1    Ray, M.2    Misra, S.3    Dutta, D.P.4    Subhankar, R.5
  • 6
    • 0347064334 scopus 로고    scopus 로고
    • Lactate and glucose as energy substrates during, and after, oxygen deprivation in rat hippocampal acute and cultured slices
    • Cater H. L., Chandratheva A., Benham C. D., Morrison B. and Sundstrom L. E. (2003) Lactate and glucose as energy substrates during, and after, oxygen deprivation in rat hippocampal acute and cultured slices. J. Neurochem. 87, 1381-1390.
    • (2003) J. Neurochem , vol.87 , pp. 1381-1390
    • Cater, H.L.1    Chandratheva, A.2    Benham, C.D.3    Morrison, B.4    Sundstrom, L.E.5
  • 9
    • 0043166646 scopus 로고    scopus 로고
    • Early mitochondrial dysfunction occurs in motor cortex and cord at the onset of disease in the Wobbler mouse
    • Dave K. R., Bradley W. G. and Perez-Pinson M. A. (2003) Early mitochondrial dysfunction occurs in motor cortex and cord at the onset of disease in the Wobbler mouse. Exp. Neurol. 182, 412-420.
    • (2003) Exp. Neurol , vol.182 , pp. 412-420
    • Dave, K.R.1    Bradley, W.G.2    Perez-Pinson, M.A.3
  • 10
    • 10044268549 scopus 로고    scopus 로고
    • Mitochondrial activation and the pyruvate paradox in a human cell line
    • De Andrade P. B. M., Casimir M. and Maechler P. (2004) Mitochondrial activation and the pyruvate paradox in a human cell line. FEBS Lett. 578, 224-228.
    • (2004) FEBS Lett , vol.578 , pp. 224-228
    • De Andrade, P.B.M.1    Casimir, M.2    Maechler, P.3
  • 11
    • 13644267272 scopus 로고    scopus 로고
    • DeHaan C., Habibi-Nazhad B., Yan E., Salloum N., Parliament M. and Allalunis-Turner J. (2004) Mutation in mitochondrial complex I ND6 subunit is associated with defective response to hypoxia in human glioma cells. Mol. Cancer 3, 19-34.
    • DeHaan C., Habibi-Nazhad B., Yan E., Salloum N., Parliament M. and Allalunis-Turner J. (2004) Mutation in mitochondrial complex I ND6 subunit is associated with defective response to hypoxia in human glioma cells. Mol. Cancer 3, 19-34.
  • 12
    • 0027234775 scopus 로고
    • Oxidation of pyruvate, malate, citrate, and cytosolic reducing equivalents by AS-30D hepatoma mitochondria
    • Dietzen D. J. and Davis E. J. (1993) Oxidation of pyruvate, malate, citrate, and cytosolic reducing equivalents by AS-30D hepatoma mitochondria. Arch. Biochem. Biophys. 305, 91-102.
    • (1993) Arch. Biochem. Biophys , vol.305 , pp. 91-102
    • Dietzen, D.J.1    Davis, E.J.2
  • 14
    • 4043108449 scopus 로고    scopus 로고
    • Mitochondrial-dependent regulation of myoblast proliferation
    • Duguez S., Sabido O. and Freyssenet D. (2004) Mitochondrial-dependent regulation of myoblast proliferation. Exp. Cell Res. 299, 27-35.
    • (2004) Exp. Cell Res , vol.299 , pp. 27-35
    • Duguez, S.1    Sabido, O.2    Freyssenet, D.3
  • 15
    • 2542561169 scopus 로고    scopus 로고
    • Akt stimulates aerobic glycolysis in cancer cells
    • Elstrom R. L., Bauer D. E., Buzzai M. et al. (2004) Akt stimulates aerobic glycolysis in cancer cells. Cancer Res. 64, 3892-3899.
    • (2004) Cancer Res , vol.64 , pp. 3892-3899
    • Elstrom, R.L.1    Bauer, D.E.2    Buzzai, M.3
  • 16
    • 0034612289 scopus 로고    scopus 로고
    • Glioblastoma multiforme: The terminator
    • Holland E. C. (2000) Glioblastoma multiforme: the terminator. Proc. Natl Acad. Sci. USA 97, 6242-6244.
    • (2000) Proc. Natl Acad. Sci. USA , vol.97 , pp. 6242-6244
    • Holland, E.C.1
  • 17
    • 0032079517 scopus 로고    scopus 로고
    • Massive mitochondrial degeneration in motor neurons triggers the onset of amyotrophic lateral sclerosis in mice expressing a mutant SOD1
    • Kong J. and Xu Z. (1998) Massive mitochondrial degeneration in motor neurons triggers the onset of amyotrophic lateral sclerosis in mice expressing a mutant SOD1. J. Neurosci. 18, 3241-3250.
    • (1998) J. Neurosci , vol.18 , pp. 3241-3250
    • Kong, J.1    Xu, Z.2
  • 18
    • 0141991084 scopus 로고    scopus 로고
    • Lambert K., Py G., Robert E. and Mercier J. (2003) Does high-sucrose diet alter skeletal muscle and liver mitochondrial respiration? Horm. Metab. Res. 35, 546-550.
    • Lambert K., Py G., Robert E. and Mercier J. (2003) Does high-sucrose diet alter skeletal muscle and liver mitochondrial respiration? Horm. Metab. Res. 35, 546-550.
  • 19
    • 0023035487 scopus 로고
    • Respiratory patterns in human brain tumors
    • Lichtor T. and Dohrmann G. J. (1986) Respiratory patterns in human brain tumors. Neurosurgery 19, 896-899.
    • (1986) Neurosurgery , vol.19 , pp. 896-899
    • Lichtor, T.1    Dohrmann, G.J.2
  • 20
    • 0030852948 scopus 로고    scopus 로고
    • Mechanism of cellular 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) reduction
    • Liu Y., Peterson D. A., Kimura H. and Schubert D. (1997) Mechanism of cellular 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) reduction. J. Neurochem. 69, 581-593.
    • (1997) J. Neurochem , vol.69 , pp. 581-593
    • Liu, Y.1    Peterson, D.A.2    Kimura, H.3    Schubert, D.4
  • 21
    • 0021750757 scopus 로고
    • Contributions of glycolysis and oxidative phosphorylation to adenosine 5′-triphosphate production in AS-30D hepatoma cells
    • Nakashima R. A., Paggi M. G. and Pedersen P. L. (1984) Contributions of glycolysis and oxidative phosphorylation to adenosine 5′-triphosphate production in AS-30D hepatoma cells. Cancer Res. 44, 5702-5706.
    • (1984) Cancer Res , vol.44 , pp. 5702-5706
    • Nakashima, R.A.1    Paggi, M.G.2    Pedersen, P.L.3
  • 22
    • 0018323499 scopus 로고
    • Measurement of growth and viability of cells in culture
    • Patterson M. K. Jr (1979) Measurement of growth and viability of cells in culture. Methods Enzymol. 58, 141-152.
    • (1979) Methods Enzymol , vol.58 , pp. 141-152
    • Patterson Jr, M.K.1
  • 23
    • 1642457265 scopus 로고    scopus 로고
    • Neuroenergetics: Calling upon astrocytes to satisfy hungry neurons
    • Pellerin L. and Magistretti P. J. (2004) Neuroenergetics: calling upon astrocytes to satisfy hungry neurons. Neuroscientist 10, 53-62.
    • (2004) Neuroscientist , vol.10 , pp. 53-62
    • Pellerin, L.1    Magistretti, P.J.2
  • 24
    • 0037628962 scopus 로고    scopus 로고
    • Astrocytes as support for axonal regeneration in the central nervous system of mammals
    • Privat A. (2003) Astrocytes as support for axonal regeneration in the central nervous system of mammals. Glia 43, 91-93.
    • (2003) Glia , vol.43 , pp. 91-93
    • Privat, A.1
  • 25
    • 27744478470 scopus 로고    scopus 로고
    • Subcellular characterization of the primordial germ cell antigen PG2 in adult oocytes
    • Püschel B., Demus U. and Viebahn C. (2005) Subcellular characterization of the primordial germ cell antigen PG2 in adult oocytes. Histochem. Cell Biol. 124, 275-284.
    • (2005) Histochem. Cell Biol , vol.124 , pp. 275-284
    • Püschel, B.1    Demus, U.2    Viebahn, C.3
  • 27
    • 17844383964 scopus 로고    scopus 로고
    • Perturbational profiling of a cell-line model of tumorigenesis by using metabolic measurements
    • Ramanathan A., Wang C. and Schreiber S. L. (2005) Perturbational profiling of a cell-line model of tumorigenesis by using metabolic measurements. Proc. Natl Acad. Sci. USA 102, 5992-5997.
    • (2005) Proc. Natl Acad. Sci. USA , vol.102 , pp. 5992-5997
    • Ramanathan, A.1    Wang, C.2    Schreiber, S.L.3
  • 28
    • 5144219600 scopus 로고    scopus 로고
    • Evidence for chronic mitochondrial impairment in the cervical spinal cord of a murine model of motor neuron disease
    • Santoro B., Bigini P., Levandis G., Nobile V., Biggiogera M., Botti F., Mennini T. and Curti D. (2004) Evidence for chronic mitochondrial impairment in the cervical spinal cord of a murine model of motor neuron disease. Neurobiol. Dis. 17, 349-357.
    • (2004) Neurobiol. Dis , vol.17 , pp. 349-357
    • Santoro, B.1    Bigini, P.2    Levandis, G.3    Nobile, V.4    Biggiogera, M.5    Botti, F.6    Mennini, T.7    Curti, D.8
  • 30
    • 0018695520 scopus 로고
    • Difference in glutamate uptake in astrocytes cultured from different brain regions
    • Schousboe A. and Divac I. (1979) Difference in glutamate uptake in astrocytes cultured from different brain regions. Brain Res. 177, 407-409.
    • (1979) Brain Res , vol.177 , pp. 407-409
    • Schousboe, A.1    Divac, I.2
  • 31
    • 0242290007 scopus 로고    scopus 로고
    • Pyruvate ameliorates post ischemic injury of rat astrocytes and protects them against PARP mediated cell death
    • Sharma P., Karian J., Sharma S., Liu S. and Mongan P. D. (2003) Pyruvate ameliorates post ischemic injury of rat astrocytes and protects them against PARP mediated cell death. Brain Res. 992, 104-113.
    • (2003) Brain Res , vol.992 , pp. 104-113
    • Sharma, P.1    Karian, J.2    Sharma, S.3    Liu, S.4    Mongan, P.D.5
  • 33
    • 0031940131 scopus 로고    scopus 로고
    • Mitochondrial heterogeneity in the brain at the cellular level
    • Sonnewald U., Hertz L. and Schousboe A. (1998) Mitochondrial heterogeneity in the brain at the cellular level. J. Cereb. Blood Flow Metab. 18, 231-237.
    • (1998) J. Cereb. Blood Flow Metab , vol.18 , pp. 231-237
    • Sonnewald, U.1    Hertz, L.2    Schousboe, A.3
  • 34
    • 0014059118 scopus 로고
    • An electron-transport system associated with the outer membrane of liver mitochondria. A biochemical and morphological study
    • Sottocasa G. L., Kuylenstierna B., Ernster L. and Bergstrand A. (1967) An electron-transport system associated with the outer membrane of liver mitochondria. A biochemical and morphological study. J. Cell Biol. 32, 415-438.
    • (1967) J. Cell Biol , vol.32 , pp. 415-438
    • Sottocasa, G.L.1    Kuylenstierna, B.2    Ernster, L.3    Bergstrand, A.4
  • 35
    • 0014444144 scopus 로고
    • A low viscosity epoxy resin medium for electron microscopy
    • Spurr A. R. (1969) A low viscosity epoxy resin medium for electron microscopy. J. Ultrastruct. Res. 26, 31-43.
    • (1969) J. Ultrastruct. Res , vol.26 , pp. 31-43
    • Spurr, A.R.1
  • 36
  • 37
    • 0009482260 scopus 로고
    • Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications
    • Towbin H., Staehelin T. and Gordon J. (1979) Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc. Natl Acad. Sci. USA 76, 4350-4354.
    • (1979) Proc. Natl Acad. Sci. USA , vol.76 , pp. 4350-4354
    • Towbin, H.1    Staehelin, T.2    Gordon, J.3
  • 38
    • 0024408986 scopus 로고
    • Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: A review
    • Vaupel P., Kallinowski F. and Okunieff P. (1989) Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: a review. Cancer Res. 49, 6449-6465.
    • (1989) Cancer Res , vol.49 , pp. 6449-6465
    • Vaupel, P.1    Kallinowski, F.2    Okunieff, P.3
  • 39
    • 33644792251 scopus 로고    scopus 로고
    • Cellular mitochondrial heterogeneity in cultured astrocytes as demonstrated by immunogold labeling of alpha-ketoglutarate dehydrogenase
    • Waagepetersen H. S., Hansen G. H., Fenger K., Lindsay J. G., Gibson G. and Schousboe A. (2006) Cellular mitochondrial heterogeneity in cultured astrocytes as demonstrated by immunogold labeling of alpha-ketoglutarate dehydrogenase. Glia 53, 225-231.
    • (2006) Glia , vol.53 , pp. 225-231
    • Waagepetersen, H.S.1    Hansen, G.H.2    Fenger, K.3    Lindsay, J.G.4    Gibson, G.5    Schousboe, A.6
  • 40
    • 0033525773 scopus 로고    scopus 로고
    • Mitochondrial diseases in man and mouse
    • Wallace D. C. (1999) Mitochondrial diseases in man and mouse. Science 283, 1482-1488.
    • (1999) Science , vol.283 , pp. 1482-1488
    • Wallace, D.C.1
  • 41
    • 12444279265 scopus 로고
    • On the origin of cancer cells
    • Warburg O. (1956) On the origin of cancer cells. Science 123, 309-314.
    • (1956) Science , vol.123 , pp. 309-314
    • Warburg, O.1
  • 42
    • 0347761272 scopus 로고    scopus 로고
    • Polarographic evaluation of mitochondrial enzymes activity in isolated mitochondria and in permeabilized human muscle cells with inherited mitochondrial defects
    • Wenchich L., Drahota Z., Honzik T., Hansikova H., Tesarova M., Zeman J. and Houstek J. (2003) Polarographic evaluation of mitochondrial enzymes activity in isolated mitochondria and in permeabilized human muscle cells with inherited mitochondrial defects. Physiol. Res. 52, 781-788.
    • (2003) Physiol. Res , vol.52 , pp. 781-788
    • Wenchich, L.1    Drahota, Z.2    Honzik, T.3    Hansikova, H.4    Tesarova, M.5    Zeman, J.6    Houstek, J.7
  • 43
    • 12144289454 scopus 로고    scopus 로고
    • Mitochondrial localization of estrogen receptor beta
    • Yang S. H., Liu R., Perez E. J. et al. (2004) Mitochondrial localization of estrogen receptor beta. Proc. Natl Acad. Sci. USA 101, 4130-4135.
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , pp. 4130-4135
    • Yang, S.H.1    Liu, R.2    Perez, E.J.3


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