Specific inhibition of interleukin-13 activity by a recombinant human single-chain immunoglobulin domain directed against the IL-13 receptor α1 chain

Biological Chemistry

Volumn 388, Issue 3, 2007, Pages 325-330

  Knackmuss, Stefan ^a   Krause, Sebastian ^b   Engel, Kathrin ^b   Reusch, Uwe ^a   Virchow, J Christian ^c   Mueller, Thomas ^d   Kraich, Michael ^d   Little, Melvin ^a   Luttmann, Werner ^c   Friedrich, Karlheinz ^b  

^a Affimed GmbH   (Germany)

^b JENA UNIVERSITY HOSPITAL   (Germany)

^c UNIVERSITY OF ROSTOCK   (Germany)

^d UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

Antagonist; Asthma; Cytokine receptors; Single chain antibody

Indexed keywords

INTERLEUKIN 13; INTERLEUKIN 13 RECEPTOR ALPHA1; RECOMBINANT PROTEIN; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY;

ARTICLE; BACTERIOPHAGE; CELL ACTIVATION; CELL PROLIFERATION; CLONE; CONTROLLED STUDY; DNA LIBRARY; DOSE RESPONSE; DRUG RECEPTOR BINDING; EMBRYO; FLOW CYTOMETRY; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IC 50; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION;

CELLS, CULTURED; HUMANS; IMMUNOGLOBULINS; INTERLEUKIN-13; INTERLEUKIN-13 RECEPTOR ALPHA1 SUBUNIT; PROTEIN BINDING; RECOMBINANT PROTEINS;

EID: 33847681014     PISSN: 14316730     EISSN: 14374315     Source Type: Journal    
DOI: 10.1515/BC.2007.036     Document Type: Article

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