Fatty acid-induced defects in insulin signalling, in myotubes derived from children, are related to ceramide production from palmitate rather than the accumulation of intramyocellular lipid

Journal of Cellular Physiology

Volumn 211, Issue 1, 2007, Pages 244-252

  Sabin, Matthew A ^a   Stewart, Claire E H ^b   Crowne, Elizabeth C ^a   Turner, Stephen J ^a   Hunt, Linda P ^a   Welsh, Gavin I ^a   Grohmann, Malcolm J ^a   Holly, Jeff M P ^a   Shield, Julian P H ^a,c  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b MANCHESTER METROPOLITAN UNIVERSITY   (United Kingdom)

^c Institute of Child Life and Health   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BROMINE DERIVATIVE; CARBON 14; CERAMIDE; FATTY ACID; INSULIN; INTRAMYOCELLULAR LIPID; LIPID; OLEIC ACID; PALMITIC ACID; PROTEIN KINASE B; SATURATED FATTY ACID; SERINE; THREONINE; UNCLASSIFIED DRUG; UNSATURATED FATTY ACID;

ARTICLE; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; ENZYME REGULATION; FATTY ACID ANALYSIS; FATTY ACID METABOLISM; FATTY ACID SYNTHESIS; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; INSULIN RESISTANCE; LIPID STORAGE; MALE; MUSCLE FIBER CULTURE; MYOTUBE; PREPUBERTY; PRIORITY JOURNAL; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

CELL DIFFERENTIATION; CELLS, CULTURED; CERAMIDES; CHILD; CHILD, PRESCHOOL; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; INFANT; INSULIN; LIPID METABOLISM; MALE; MUSCLE FIBERS; OLEIC ACID; OXAZINES; PALMITATES; PHOSPHOPROTEINS; PHOSPHOSERINE; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; TIME FACTORS;

EID: 33847628837     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcp.20922     Document Type: Article

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