Peptidases play an important role in cataractogenesis: An immunohistochemical study on lenses derived from Shumiya cataract rats

Histochemical Journal

Volumn 33, Issue 9-10, 2001, Pages 511-521

  Zhang, Hui ^a   Yamamoto, Yishio ^a   Shumiya, Seigo ^b   Kunimatsu, Mitoshi ^c   Nishi, Katsuji ^a   Ohkubo, Iwao ^a   Kani, Kazutaka ^a  

^a SHIGA UNIVERSITY OF MEDICAL SCIENCE   (Japan)

^b TOKYO METROPOLITAN INSTITUTE OF GERONTOLOGY   (Japan)

^c NAGOYA CITY UNIV MEDICAL SCHOOL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA CRYSTALLIN; BETA CRYSTALLIN; CALPAIN; DIPEPTIDYL PEPTIDASE; EXOPEPTIDASE; LENS PROTEIN; MEMBRANE ENZYME; MICROSOMAL AMINOPEPTIDASE; PROTEASOME; PROTEINASE;

AGE; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CATARACT; CATARACTOGENESIS; CONTROLLED STUDY; ENZYME ACTIVITY; IMMUNOHISTOCHEMISTRY; LENS EPITHELIUM; LENS FIBER; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN METABOLISM; PROTEIN TRANSPORT; RAT; STRAIN DIFFERENCE;

AGE FACTORS; ANIMALS; CATARACT; CRYSTALLINS; ENDOPEPTIDASES; EXOPEPTIDASES; IMMUNOHISTOCHEMISTRY; LENS, CRYSTALLINE; MODELS, BIOLOGICAL; RATS; RATS, INBRED STRAINS; RATS, WISTAR;

ANIMALIA;

EID: 0035568856     PISSN: 00182214     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1014943522613     Document Type: Article

References (25)

1. Proteolytic cleavage of N-Succ-Leu-Leu-Val-Tyr-AMC by the proteasome in lens epithelium from clear and cataractous human lenses
2. Human cataractogenesis: A review
3. Interaction between αB-crystallin and the human 20S proteasomal subunit C8/α7
4. Sequence analysis of lens β-crystallins suggests involvement of calpain in cataract formation
5. Regional distribution of free calcium in selenite cataract: Relation to calpain II
6. Dipeptidyl peptidase II from porcine seminal plasma: Purification, characterization, and its homology to granzymes, cytotoxic cell proteinases (CCP 1-4)
7. Alanyl aminopeptidase from human seminal plasma purification, characterization and immunohistochemical localization in the male genital tract
8. Evidence for the involvement of calpain in cataractogenesis in Shumiya cataract rat (SCR)
9. Aminoguanidine-treatment results in the inhibition of lens opacification and calpain-mediated proteolysis in Shumiya cataract rat (SCR)
10. Interaction of human calpains I and II with high molecular weight and low molecular weight kininogens and their heavy chain: Mechanism of interaction and the role of divalent cations
11. Alteration of lens disulfide bonds in newly developed hereditary cataract rat
12. Lens proteasome shows enhanced rates of degradation of hydroxyl radical modified α-crystallin
13. Human erythrocyte multicatalytic proteinase: Activation and binding to sulfated galacto- and lactosylceramides
14. Dipeptidyl peptidase III from rat liver cytosol: Purification, molecular cloning and immunohistochemical localization
15. Distribution of m-calpain proenzyme in the brain and other neural tissues in the rat
16. Differential metabolism and leakage of protein in inherited cataract and a normal lens cultured with ouabain
17. Protective effects of calpain inhibitor for prolonged hypothermic cardiac preservation
18. Selenite nuclear cataract: Review of the model
19. Establishment of the hereditary cataract strain (SCR) and genetic analysis
20. Proteases in the Emory Mouse cataract
21. Eye lens protein and transparency: From light transmission theory to solution X-ray structural analysis
22. Protein oxidation and loss of protease activity may lead to cataract formation in the aged lens
23. Tripeptidyl peptidases: Enzymes that count
24. Immunohistochemical study of calpain-mediated α-crystallin proteolysis in the UPL rat hereditary cataract
25. Isolation and characterization of alanylaminopeptidase from rat liver cytosol as a puromycin-sensitive enkephalin degrading aminopeptidase