K1 protein of human herpesvirus 8 suppresses lymphoma cell Fas-mediated apoptosis

Blood

Volumn 109, Issue 5, 2007, Pages 2174-2182

  Wang, Suizhao ^a   Wang, Shu ^a   Maeng, Hoyoung ^a   Young, Daniel P ^a   Prakash, Om ^b   Fayad, Luis E ^a   Younes, Anas ^a   Samaniego, Felipe ^a,c  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF TEXAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOHEXIMIDE; FAS ANTIBODY; FAS ASSOCIATED DEATH DOMAIN PROTEIN; FAS LIGAND; PROCASPASE 8; PROTEIN K1; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNCLASSIFIED DRUG; VIRUS PROTEIN;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; DRUG MECHANISM; HUMAN; HUMAN CELL; LIVER CELL; LYMPHOMA CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN MOTIF;

EID: 33847369549     PISSN: 00064971     EISSN: 00064971     Source Type: Journal    
DOI: 10.1182/blood-2006-02-003178     Document Type: Article

References (49)

1. Cesarman E, Chang Y, Moore PS, Said JW, Knowles DM. Kaposi's sarcoma-associated herpesvirus-like DNA sequences in AIDS-related body-cavity-based lymphomas. N Engl J Med. 1995;332:1186-1191.
2. Cesarman E, Knowles DM. The role of Kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8) in lymphoproliferative diseases. Semin Cancer Biol. 1999;9:165-174.
3. Lee H, Veazey R, Williams K, et al. Deregulation of cell growth by the K1 gene of Kaposi's sarcoma-associated herpesvirus. Nat Med. 1998;4:435-440.
4. Prakash O, Tang ZY, Peng X, et al. Tumorigenesis and aberrant signaling in transgenic mice expressing the human herpesvirus-8 K1 gene. J Natl Cancer Inst. 2002;94:926-935.
5. Lee BS, Lee SH, Feng P, Chang H, Cho NH, Jung JU. Characterization of the Kaposi's sarcoma-associated herpesvirus K1 signalosome. J Virol. 2005;79:12173-12184.
6. Samaniego F, Pati S, Karp J, Prakash O, Bose D. Human herpesvirus 8 k1-associated nuclear factor-kappa B-dependent promoter activity: role in Kaposi's sarcoma inflammation? J Natl Cancer Inst Monogr. 2001;28:15-23.
7. Merchant M, Caldwell RG, Longnecker R. The LMP2A ITAM is essential for providing B cells with development and survival signals in vivo. J Virol. 2000;74:9115-9124.
8. Kimura T, Kihara H, Bhattacharyya S, Sakamoto H, Appella E, Siraganian RP. Downstream signaling molecules bind to different phosphorylated immunoreceptor tyrosine-based activation motif (ITAM) peptides of the high affinity IgE receptor. J Biol Chem. 1996;271:27962-27968.
9. Prakash O, Swamy OR, Peng X, et al. Activation of Src kinase Lyn by the Kaposi sarcomaassociated herpesvirus K1 protein: implications for lymphomagenesis. Blood. 2005;105:3987-3994.
10. Paulose-Murphy M, Ha N-K, Xiang C, et al. Transcription program of human herpesvirus 8 (Kaposi's Sarcoma-associated herpesvirus). J Virol. 2001;75:4843-4853.
11. Wang L, Dittmer DP, Tomlinson CC, Fakhari FD, Damania B. Immortalization of primary endothelial cells by the K1 protein of Kaposi's sarcoma-associated herpesvirus. Cancer Res. 2006;66:3658-3666.
12. Lee BS, Alvarez X, Ishido S, Lackner AA, Jung JU. Inhibition of intracellular transport of B cell antigen receptor complexes by Kaposi's sarcoma-associated herpesvirus K1. J Exp Med. 2000;192:11-21.
13. Nicholas J. Human herpesvirus-8-encoded signalling ligands and receptors. J Biomed Sci. 2003;10:475-489.
14. Guasparri I, Keller SA, Cesarman E. KSHV vFLIP is essential for the survival of infected lymphoma cells. J Exp Med. 2004;199:993-1003.
15. Keller SA, Schattner EJ, Cesarman E. Inhibition of NF-kappa B induces apoptosis of KSHV-infected primary effusion lymphoma cells. Blood. 2000;96:2537-2542.
16. Keller SA, Hernandez-Hopkins D, Vider J, et al. NF-kappa B is essential for the progression of KSHV- and EBV-infected lymphomas in vivo. Blood. 2006;107:3295-3302.
17. Huang DC, Hahne M, Schroeter M, et al. Activation of Fas by FasL induces apoptosis by a mechanism that cannot be blocked by Bcl-2 or Bcl-x(L). Proc Natl Acad Sci U S A. 1999;96:14871-14876.
18. Peter ME, Krammer PH. The CD95(APO-1/Fas) DISC and beyond. Cell Death Differ. 2003;10:26-35.
19. Arvanitakis L, Mesri EA, Nador RG, et al. Establishment and characterization of a primary effusion (body cavity-based) lymphoma cell line (BC-3) harboring Kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8) in the absence of Epstein-Barr virus. Blood. 1996;88:2648-2654.
20. Lee BS, Connole M, Tang Z, Harris NL, Jung JU. Structural analysis of the Kaposi's sarcoma-associated herpesvirus K1 protein. J Virol. 2003;77:8072-8086.
21. Locksley RM, Killeen N, Lenardo MJ. The TNF and TNF receptor superfamilies: integrating mammalian biology. Cell. 2001;104:487-501.
22. Bodmer JL, Holler N, Reynard S, et al. TRAIL receptor-2 signals apoptosis through FADD and caspase-8. Nat Cell Biol. 2000;2:241-243.
23. Xiao C, Yang BF, Asadi N, Beguinot F, Hao C. TRAIL-induced death-inducing signaling complex (DISC) and its modulation by c-FLIP and PED/PEA-15 in glioma cells. J Biol Chem. 2002;277:25020-25025.
24. Doostzadeh-Cizeron J, Evans R, Yin S, Goodrich DW. Apoptosis induced by the nuclear death domain protein p84N5 is inhibited by association with Rb protein. Mol Biol Cell. 1999;10:3251-3261.
25. Fritz G, Brachetti C, Kaina B. Lovastatin causes sensitization of HeLa cells to ionizing radiationinduced apoptosis by the abrogation of G2 blockage. Int J Radiat Biol. 2003;79:601-610.
26. Mirzaie-Joniani H, Eriksson D, Johansson A, et al. Apoptosis in HeLa Hep2 cells is induced by low-dose, low-dose-rate radiation. Radiat Res. 2002;158:634-640.
27. Barillari G, Sgadari C, Fiorelli V, et al. The Tat protein of human immunodeficiency virus type-1 promotes vascular cell growth and locomotion by engaging the alpha5beta1 and alphavbeta3 integrins and by mobilizing sequestered basic fibroblast growth factor. Blood. 1999;94:663-672.
28. Valk PJM, Joosten M, Vankan Y, Lowenberg B, Delwel R. A rapid RT-PCR based method to isolate complementary DNA fragments flanking retrovirus integration sites. Nucleic Acids Res. 1997;25:4419-4421.
29. Daniel WW. Hypothesis testing. In: Biostatistics: A Foundation for Analysis in the Health Sciences. Somerset, NJ: John Wiley & Sons; 1974:159-201.
30. Baatout S, Derradji H. Cytometric methods to analyze radiation effects. J Biol Regul Homeost Agents. 2004;18:101-105.
31. Salvesen GS, Dixit VM. Caspase activation: the induced-proximity model. Proc Natl Acad Sci U S A. 1999;96:10964-10967.
32. Medema JP, Scaffidi C, Kischkel FC, et al. FLICE is activated by association with the CD95 death-inducing signaling complex (DISC). EMBO J. 1997;16:2794-2804.
33. Hennino A, Berard M, Casamayor-Palleja M, Krammer PH, Defrance T. Regulation of the Fas death pathway by FLICE-inhibitory protein in primary human B cells. J Immunol. 2000;165:3023-3030.
34. Haga S, Terui K, Zhang HQ, et al. Stat3 protects against Fas-induced liver injury by redox-dependent and -independent mechanisms. J Clin Invest. 2003;112:989-998.
35. Schuchmann M, Varfolomeev EE, Hermann F, et al. Dominant negative MORT1/FADD rescues mice from CD95 and TNF-induced liver failure. Hepatology. 2003;37:129-135.
36. Zender L, Hutker S, Liedtke C, et al. Caspase 8 small interfering RNA prevents acute liver failure in mice. Proc Natl Acad Sci U S A. 2003;100:7797-7802.
37. Walczak H, Degli-Esposti MA, Johnson RS, et al. TRAIL-R2: a novel apoptosis-mediating receptor for TRAIL. EMBO J. 1997;16:5386-5397.
38. Embree-Ku M, Venturini D, Boekelheide K. Fas is involved in the p53-dependent apoptotic response to ionizing radiation in mouse testis. Biol Reprod. 2002;66:1456-1461.
39. Wang X, DeFrances MC, Dai Y, et al. A mechanism of cell survival: sequestration of Fas by the HGF receptor Met. Mol Cell. 2002;9:411-421.
40. Hauptschein RS, Sloan KE, Torella C, et al. Functional proteomic screen identifies a modulating role for CD44 in death receptor-mediated apoptosis. Cancer Res. 2005;65:1887-1896.
41. Isakov N. ITIMs and ITAMs: the Yin and Yang of antigen and Fc receptor-linked signaling machinery. Immunol Res. 1997;16:85-100.
42. Isakov N. Immunoreceptor tyrosine-based activation motif (ITAM), a unique module linking antigen and Fc receptors to their signaling cascades. J Leukoc Biol. 1997;61:6-16.
43. Combadiáere B, Freedman M, Chen L, et al. Qualitative and quantitative contributions of the T cell receptor zeta chain to mature T cell apoptosis. J Exp Med. 1996;183:2109-2117.
44. Johnson SA, Pleiman CM, Pao L, Schneringer J, Hippen K, Cambier JC. Phosphorylated immunoreceptor signaling motifs (ITAMs) exhibit unique abilities to bind and activate Lyn and Syk tyrosine kinases. J Immunol. 1995;155:4596-4603.
45. Fruehling S, Longnecker R. The immunoreceptor tyrosine-based activation motif of Epstein-Barr virus LMP2A is essential for blocking BCRmediated signal transduction. Virology. 1997;235:241-251.
46. Fruehling S, Lee SK, Herrold R, et al. Identification of latent membrane protein 2A (LMP2A) domains essential for the LMP2A dominant-negative effect on B-lymphocyte surface immunoglobulin signal transduction. J Virol 1998;70:6216-6226.
47. Glenn M, Rainbow L, Aurade F, Davison A, Schulz TF. Identification of a spliced gene from Kaposi's Sarcoma-associated herpesvirus encoding a protein with similarities to latent membrane proteins 1 and 2A of Epstein-Barr Virus. J Virol. 1999;73:6953-6963.
48. Geimonen E, Farooqui Y, LaMonica R, Springer K, Gavrilovskaya I, Mackow E. Hantavirus immunoglobulin tyrosine activation motifs (ITAMs) mediate viral protein interactions with cellular signaling elements [abstract]. FASEB J. 1999;13:Abstract 1577.
49. Lee H, Guo J, Li M, et al. Identification of an immunoreceptor tyrosine-based activation motif of K1 transforming protein of Kaposi's sarcoma-associated herpesvirus. Mol Cell Biol. 1998;18:5219-5228.