Understanding the regulation mechanisms of PAF receptor by agonists and antagonists: Molecular modeling and molecular dynamics simulation studies

Proteins: Structure, Function and Genetics

Volumn 67, Issue 1, 2007, Pages 41-52

  Gui, Chunshan ^a,b   Zhu, Weiliang ^a,c   Chen, Gang ^b   Luo, Xiaomin ^a   Liew, Oi W ^b   Puah, Chum M ^b   Chen, Kaixian ^a   Jiang, Hualiang ^a  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

^b SINGAPORE POLYTECHNIC   (Singapore)

^c EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

GPCR; Homology modeling; Molecular docking; Molecular dynamics simulation; PAFR

Indexed keywords

G PROTEIN COUPLED RECEPTOR; GINKGOLIDE; RHODOPSIN; THROMBOCYTE ACTIVATING FACTOR ANTAGONIST; THROMBOCYTE ACTIVATING FACTOR RECEPTOR; THROMBOCYTE ACTIVATING FACTOR RECEPTOR AFFECTING AGENT;

ARTICLE; CRYSTAL STRUCTURE; LIGAND BINDING; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; MOLECULAR MODEL; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS; THREE DIMENSIONAL IMAGING; THROMBOCYTE ACTIVATION;

ALGORITHMS; AMINO ACID SEQUENCE; ANIMALS; CATTLE; COMPUTATIONAL BIOLOGY; COMPUTER SIMULATION; GINKGOLIDES; HUMANS; HYDROGEN BONDING; LACTONES; LIPID BILAYERS; MODELS, BIOLOGICAL; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PLATELET ACTIVATING FACTOR; PLATELET MEMBRANE GLYCOPROTEINS; PROTEIN STRUCTURE, SECONDARY; RECEPTORS, G-PROTEIN-COUPLED; RHODOPSIN; SEQUENCE ALIGNMENT; SIGNAL TRANSDUCTION;

EID: 33847355633     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.21213     Document Type: Article

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