The nucleotide analog cidofovir suppresses basic fibroblast growth factor (FGF2) expression and signaling and induces apoptosis in FGF2-overexpressing endothelial cells

Molecular Pharmacology

Volumn 71, Issue 3, 2007, Pages 695-703

  Liekens, Sandra ^a   Gijsbers, Sofie ^a   Vanstreels, Els ^a   Daelemans, Dirk ^a   De Clercq, Erik ^a   Hatse, Sigrid ^a  

^a REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR; CASPASE 3; CIDOFOVIR; CYTOCHROME C; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NUCLEOTIDE DERIVATIVE; PROTEIN BAD; PROTEIN BAX; PROTEIN BCL 2; PROTEIN KINASE B; PROTEIN P53; TUMOR SUPPRESSOR PROTEIN;

ANIMAL CELL; AORTA; APOPTOSIS; ARTICLE; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CONTROLLED STUDY; DIPLOIDY; DRUG ACTIVITY; ENDOTHELIUM CELL; ENZYME ACTIVATION; GENE OVEREXPRESSION; MITOCHONDRION; MOUSE; NONHUMAN; PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; STATISTICAL SIGNIFICANCE; WESTERN BLOTTING;

ANIMALS; ANTIVIRAL AGENTS; APOPTOSIS; CELL PROLIFERATION; CELLS, CULTURED; CYTOCHROMES C; CYTOSINE; ENDOTHELIAL CELLS; FIBROBLAST GROWTH FACTOR 2; MICE; PHOSPHONIC ACIDS; POLY(ADP-RIBOSE) POLYMERASES; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 33847133080     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.106.026559     Document Type: Article

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