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Volumn 56, Issue 1, 1999, Pages 204-213

Modulation of fibroblast growth factor-2 receptor binding, signaling, and mitogenic activity by heparin-mimicking polysulfonated compounds

Author keywords

[No Author keywords available]

Indexed keywords

FIBROBLAST GROWTH FACTOR 2; FIBROBLAST GROWTH FACTOR RECEPTOR; POLY(2 ACRYLAMIDO 2 METHYL 1 PROPANESULFONIC ACID); POLYANETHOLESULFONIC ACID; POLYSTYRENESULFONIC ACID; PROTEOHEPARAN SULFATE; SULFONIC ACID DERIVATIVE; TYROSINE KINASE RECEPTOR; UNCLASSIFIED DRUG;

EID: 0033061257     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.56.1.204     Document Type: Article
Times cited : (94)

References (42)
  • 2
    • 0029133267 scopus 로고
    • Elucidation of a signalling pathway induced by FGF-2 leading to uPA gene expression in NIH 3T3 fibroblasts
    • Besser D, Presta M and Nagamine Y (1995) Elucidation of a signalling pathway induced by FGF-2 leading to uPA gene expression in NIH 3T3 fibroblasts. Cell Growth & Differ 6:1009-1017.
    • (1995) Cell Growth & Differ , vol.6 , pp. 1009-1017
    • Besser, D.1    Presta, M.2    Nagamine, Y.3
  • 3
    • 0028075526 scopus 로고
    • Different effects of mucosal, bovine lung and chemically modified heparin on selected biological properties of basic fibroblast growth factor
    • Coltrini D, Rusnati M, Zoppetti G, Oreste P, Grazioli G, Naggi A and Presta M (1994) Different effects of mucosal, bovine lung and chemically modified heparin on selected biological properties of basic fibroblast growth factor. Biochem J 303:583-590.
    • (1994) Biochem J , vol.303 , pp. 583-590
    • Coltrini, D.1    Rusnati, M.2    Zoppetti, G.3    Oreste, P.4    Grazioli, G.5    Naggi, A.6    Presta, M.7
  • 4
    • 0027173328 scopus 로고
    • Biochemical bases of the interaction of human basic fibroblast growth factor with glycosaminoglycans. New insights from trypsin digestion studies
    • Coltrini D, Rusnati M, Zoppetti G, Oreste P, Isacchi A, Caccia P, Bergonzoni L and Presta M (1993) Biochemical bases of the interaction of human basic fibroblast growth factor with glycosaminoglycans. New insights from trypsin digestion studies. Bur J Biochem 214:51-58.
    • (1993) Bur J Biochem , vol.214 , pp. 51-58
    • Coltrini, D.1    Rusnati, M.2    Zoppetti, G.3    Oreste, P.4    Isacchi, A.5    Caccia, P.6    Bergonzoni, L.7    Presta, M.8
  • 5
    • 0027459523 scopus 로고
    • Perivascular and intravenous administration of basic fibroblast growth factor: Vascular and solid organ deposition
    • Edelman ER, Nugent MA and Karnovsky MJ (1993) Perivascular and intravenous administration of basic fibroblast growth factor: Vascular and solid organ deposition. Proc Natl Acad Sci USA 90:1513-1517.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 1513-1517
    • Edelman, E.R.1    Nugent, M.A.2    Karnovsky, M.J.3
  • 6
    • 0027321067 scopus 로고
    • Refinement of the structure of human basic fibroblast growth factor at 1.6 Å resolution and analysis of presumed heparin binding sites by selenate substitution
    • Erikseon AE, Cousens LS and Matthews BW (1993) Refinement of the structure of human basic fibroblast growth factor at 1.6 Å resolution and analysis of presumed heparin binding sites by selenate substitution. Protein Sci 2:1274-1284.
    • (1993) Protein Sci , vol.2 , pp. 1274-1284
    • Erikseon, A.E.1    Cousens, L.S.2    Matthews, B.W.3
  • 7
    • 0025823018 scopus 로고
    • Genetic analysis of proteoglycan structure, function and metabolism
    • Esko JD (1991) Genetic analysis of proteoglycan structure, function and metabolism. Curr Opin Cell Biol 3:805-816.
    • (1991) Curr Opin Cell Biol , vol.3 , pp. 805-816
    • Esko, J.D.1
  • 8
    • 0030729838 scopus 로고    scopus 로고
    • An extensively modified version of MolScript which includes greatly enhanced colouring capabilities
    • Esnouf RM (1997) An extensively modified version of MolScript which includes greatly enhanced colouring capabilities. J Mol Graph Model 15:132-134.
    • (1997) J Mol Graph Model , vol.15 , pp. 132-134
    • Esnouf, R.M.1
  • 11
    • 0028840752 scopus 로고
    • Antiproliferative and angiostatic activity of suramin analogues
    • Firsching A, Nickel P, Mora P and Allolio B (1995) Antiproliferative and angiostatic activity of suramin analogues. Cancer Res 55:4957-4961.
    • (1995) Cancer Res , vol.55 , pp. 4957-4961
    • Firsching, A.1    Nickel, P.2    Mora, P.3    Allolio, B.4
  • 12
    • 0025788685 scopus 로고
    • Multiple forms of bFGF: Differential nuclear and cell surface localization
    • Florkiewicz RZ, Baird A and Gonzalez AM (1991) Multiple forms of bFGF: Differential nuclear and cell surface localization. Growth Factors 4:265-275.
    • (1991) Growth Factors , vol.4 , pp. 265-275
    • Florkiewicz, R.Z.1    Baird, A.2    Gonzalez, A.M.3
  • 13
    • 0008563256 scopus 로고
    • Human basic fibroblast growth factor gene encodes four polypeptides: Three initiate translation from non-AUG codons
    • Florkiewicz RZ and Sommer A (1989) Human basic fibroblast growth factor gene encodes four polypeptides: Three initiate translation from non-AUG codons. Proc Natl Acad Sci USA 86:3978-3981.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 3978-3981
    • Florkiewicz, R.Z.1    Sommer, A.2
  • 14
    • 0027987884 scopus 로고
    • Interaction of high molecular weight basic fibroblast growth factor (bFGF) with endothelium: Biological activity and intracellular fate of human recombinant Mr 24,000 bFGF
    • Gualandris A, Urbinati C, Rusnati M, Ziche M and Presta M (1994) Interaction of high molecular weight basic fibroblast growth factor (bFGF) with endothelium: Biological activity and intracellular fate of human recombinant Mr 24,000 bFGF. J Cell Physiol 161:149-159.
    • (1994) J Cell Physiol , vol.161 , pp. 149-159
    • Gualandris, A.1    Urbinati, C.2    Rusnati, M.3    Ziche, M.4    Presta, M.5
  • 15
    • 0027428744 scopus 로고
    • Activating and inhibitory sequences for FGF-2 (basic FGF). Distinct requirements for FGF-1, FGF-2 and FGF-4
    • Guimond S, Maccarana M, Olwin BB, Lindahl U and Rapraeger AC (1993) Activating and inhibitory sequences for FGF-2 (basic FGF). Distinct requirements for FGF-1, FGF-2 and FGF-4. J Biol Chem 268:23906-23914.
    • (1993) J Biol Chem , vol.268 , pp. 23906-23914
    • Guimond, S.1    Maccarana, M.2    Olwin, B.B.3    Lindahl, U.4    Rapraeger, A.C.5
  • 16
    • 0001452803 scopus 로고    scopus 로고
    • Heparin-induced self-association of fibroblast growth factor-2. Evidence for two oligomerization processes
    • Herr AB, Ornitz DM, Sasisekharan R, Venkataraman G and Waksman G (1997) Heparin-induced self-association of fibroblast growth factor-2. Evidence for two oligomerization processes. J Biol Chem 272:16382-16389.
    • (1997) J Biol Chem , vol.272 , pp. 16382-16389
    • Herr, A.B.1    Ornitz, D.M.2    Sasisekharan, R.3    Venkataraman, G.4    Waksman, G.5
  • 17
    • 0027418048 scopus 로고
    • Preparation of affinity-fractionated, heparin-derived oligosaccharides and their effects on selected biological activities mediated by basic fibroblast growth factor
    • Ishihara M, Tyrrell DJ, Stauber GB, Brown S, Cousens LS and Stack RJ (1993) Preparation of affinity-fractionated, heparin-derived oligosaccharides and their effects on selected biological activities mediated by basic fibroblast growth factor. J Biol Chem 268:4675-4683.
    • (1993) J Biol Chem , vol.268 , pp. 4675-4683
    • Ishihara, M.1    Tyrrell, D.J.2    Stauber, G.B.3    Brown, S.4    Cousens, L.S.5    Stack, R.J.6
  • 18
    • 0027344852 scopus 로고
    • Structural and functional diversity in the FGF receptor multigene family
    • Johnson DE and Williams LT (1993) Structural and functional diversity in the FGF receptor multigene family. Adv Cancer Res 60:1-41.
    • (1993) Adv Cancer Res , vol.60 , pp. 1-41
    • Johnson, D.E.1    Williams, L.T.2
  • 19
    • 0026244229 scopus 로고
    • MOLSCRIPT: A program to produce both detailed and schematic plots of protein structures
    • Kraulis PJ (1991) MOLSCRIPT: A program to produce both detailed and schematic plots of protein structures. J Appl Crystallogr 24:916-950.
    • (1991) J Appl Crystallogr , vol.24 , pp. 916-950
    • Kraulis, P.J.1
  • 20
    • 0030634055 scopus 로고    scopus 로고
    • The sulfonic acid polymers PAMPS [poly(2-acrylamido-2-methyl-1-propanesulfonic acid)] and related analogues are highly potent inhibitors of angiogenesis
    • Liekens S, Neyts J, Degrève B and De Clercq E (1997) The sulfonic acid polymers PAMPS [poly(2-acrylamido-2-methyl-1-propanesulfonic acid)] and related analogues are highly potent inhibitors of angiogenesis. Oncol Res 9:173-181.
    • (1997) Oncol Res , vol.9 , pp. 173-181
    • Liekens, S.1    Neyts, J.2    Degrève, B.3    De Clercq, E.4
  • 21
    • 0028057108 scopus 로고
    • Raster3D version 2.0. A program for photorealistic molecular graphics
    • Merritt EA and Murphy MEP (1994) Raster3D version 2.0. A program for photorealistic molecular graphics. Acta Crystallogr D50:869-873.
    • (1994) Acta Crystallogr , vol.D50 , pp. 869-873
    • Merritt, E.A.1    Murphy, M.E.P.2
  • 23
    • 0027052914 scopus 로고
    • Basic fibroblast growth factor (bFGF) dissociates rapidly from heparan sulfates but slowly from receptors. Implications for mechanisms of bFGF release from pericellular matrix
    • Moscatelli D (1992) Basic fibroblast growth factor (bFGF) dissociates rapidly from heparan sulfates but slowly from receptors. Implications for mechanisms of bFGF release from pericellular matrix. J Biol Chem 267:25803-25809.
    • (1992) J Biol Chem , vol.267 , pp. 25803-25809
    • Moscatelli, D.1
  • 25
    • 0029719792 scopus 로고    scopus 로고
    • Basic-fibroblast-growth-factor-mediated de novo angiogenesis is more effectively suppressed by low-molecular-weight than by high-molecular-weight heparin
    • Norrby K and Ostergaard P (1996) Basic-fibroblast-growth-factor-mediated de novo angiogenesis is more effectively suppressed by low-molecular-weight than by high-molecular-weight heparin. Int J Microcirc Clin Exp 16:8-15.
    • (1996) Int J Microcirc Clin Exp , vol.16 , pp. 8-15
    • Norrby, K.1    Ostergaard, P.2
  • 27
    • 0030890708 scopus 로고    scopus 로고
    • Manipulating angiogenesis. From basic science to the bedside
    • Pepper MS (1997) Manipulating angiogenesis. From basic science to the bedside. Arterioscler Thromb Vasc Biol 17:605-619.
    • (1997) Arterioscler Thromb Vasc Biol , vol.17 , pp. 605-619
    • Pepper, M.S.1
  • 28
    • 0026729378 scopus 로고
    • Suramin prevents neovascularization and tumour growth through blocking of basic fibroblast growth factor activity
    • Pesenti E, Sola F, Mongelli N, Grandi M and Spreafico F (1992) Suramin prevents neovascularization and tumour growth through blocking of basic fibroblast growth factor activity. Br J Cancer 66:367-372.
    • (1992) Br J Cancer , vol.66 , pp. 367-372
    • Pesenti, E.1    Sola, F.2    Mongelli, N.3    Grandi, M.4    Spreafico, F.5
  • 29
    • 0022820965 scopus 로고
    • Purification from a human hepatoma cell line of a basic fibroblast growth factor-like molecule that stimulates capillary endothelial cell plasminogen activator production, DNA synthesis and migration
    • Presta M, Moscatelli D, Joseph-Silverstein J and Rifkin DB (1986) Purification from a human hepatoma cell line of a basic fibroblast growth factor-like molecule that stimulates capillary endothelial cell plasminogen activator production, DNA synthesis and migration. Mol Cell Biol 6:4060-4066.
    • (1986) Mol Cell Biol , vol.6 , pp. 4060-4066
    • Presta, M.1    Moscatelli, D.2    Joseph-Silverstein, J.3    Rifkin, D.B.4
  • 30
    • 0026213963 scopus 로고
    • Basic fibroblast growth factor requires a long-lasting activation of protein kinase C to induce cell proliferation in transformed fetal bovine aortic endothelial cells
    • Presta M, Tiberio L, Rusnati M, Dell'Era P and Ragnotti G (1991) Basic fibroblast growth factor requires a long-lasting activation of protein kinase C to induce cell proliferation in transformed fetal bovine aortic endothelial cells. Cell Regul 2:719-726.
    • (1991) Cell Regul , vol.2 , pp. 719-726
    • Presta, M.1    Tiberio, L.2    Rusnati, M.3    Dell'Era, P.4    Ragnotti, G.5
  • 31
    • 0029111677 scopus 로고
    • Endogenous basic fibroblast growth factor is implicated in the vascularization of the chick embryo chorioallantoic membrane
    • Ribatti D, Urbinati C, Nico B, Rusnati M, Roncali L and Presta M (1995) Endogenous basic fibroblast growth factor is implicated in the vascularization of the chick embryo chorioallantoic membrane. Dev Biol 170:39-49.
    • (1995) Dev Biol , vol.170 , pp. 39-49
    • Ribatti, D.1    Urbinati, C.2    Nico, B.3    Rusnati, M.4    Roncali, L.5    Presta, M.6
  • 32
    • 0028892277 scopus 로고
    • Fibroblast growth factor-2 can mediate cell attachment by linking receptors and heparan sulfate proteoglycans on neighboring cells
    • Richard C, Liuzzo JP and Moscatelli D (1995) Fibroblast growth factor-2 can mediate cell attachment by linking receptors and heparan sulfate proteoglycans on neighboring cells. J Biol Chem 270:24188-24196.
    • (1995) J Biol Chem , vol.270 , pp. 24188-24196
    • Richard, C.1    Liuzzo, J.P.2    Moscatelli, D.3
  • 33
    • 0028068096 scopus 로고
    • Distinct role of 2-O-, N-, and 6-O-sulfate groups of heparin in the formation of the ternary complex with basic fibroblast growth factor and soluble FGF receptor-1
    • Rusnati M, Coltrini D, Dell'Era P, Zopetti G, Oreste P, Valsasina B and Presta M (1994) Distinct role of 2-O-, N-, and 6-O-sulfate groups of heparin in the formation of the ternary complex with basic fibroblast growth factor and soluble FGF receptor-1. Biochem Biophys Res Commun 203:450-458.
    • (1994) Biochem Biophys Res Commun , vol.203 , pp. 450-458
    • Rusnati, M.1    Coltrini, D.2    Dell'Era, P.3    Zopetti, G.4    Oreste, P.5    Valsasina, B.6    Presta, M.7
  • 34
    • 0023687871 scopus 로고
    • Endothelial cell-derived heparan sulfate binds basic fibroblast growth factor and protects it from proteolytic degradation
    • Saksela O, Moscatelli D, Sommer A and Rifkin DB (1988) Endothelial cell-derived heparan sulfate binds basic fibroblast growth factor and protects it from proteolytic degradation. J Cell Biol 107:743-751.
    • (1988) J Cell Biol , vol.107 , pp. 743-751
    • Saksela, O.1    Moscatelli, D.2    Sommer, A.3    Rifkin, D.B.4
  • 36
    • 0028825543 scopus 로고
    • Regulation of growth factor activation by proteoglycans: What is the role of the low affinity receptors?
    • Schlessinger J, Lax I and Lemmon M (1995) Regulation of growth factor activation by proteoglycans: What is the role of the low affinity receptors? Cell 83:357-360.
    • (1995) Cell , vol.83 , pp. 357-360
    • Schlessinger, J.1    Lax, I.2    Lemmon, M.3
  • 38
    • 0028218987 scopus 로고
    • Energetic characterization of the basic fibroblast growth factor-heparin interaction: Identification of the heparin binding domain
    • Thompson LD, Pantoliano MW and Springer BA ( 1994) Energetic characterization of the basic fibroblast growth factor-heparin interaction: Identification of the heparin binding domain. Biochemistry 33:3831-3840.
    • (1994) Biochemistry , vol.33 , pp. 3831-3840
    • Thompson, L.D.1    Pantoliano, M.W.2    Springer, B.A.3
  • 39
    • 0027762048 scopus 로고
    • Angiogenic role of endogenous basic fibroblast growth factor released by rat aorta after injury
    • Villaschi S and Nicosia RF (1993) Angiogenic role of endogenous basic fibroblast growth factor released by rat aorta after injury. Am J Pathol 143:181-190.
    • (1993) Am J Pathol , vol.143 , pp. 181-190
    • Villaschi, S.1    Nicosia, R.F.2
  • 40
    • 0028039867 scopus 로고
    • Specific heparan sulfate saccharides mediate the activity of basic fibroblast growth factor
    • Walker A, Turnbull JE and Gallagher JT (1994) Specific heparan sulfate saccharides mediate the activity of basic fibroblast growth factor. J Biol Chem 269:931-935.
    • (1994) J Biol Chem , vol.269 , pp. 931-935
    • Walker, A.1    Turnbull, J.E.2    Gallagher, J.T.3
  • 41
    • 0025976838 scopus 로고
    • Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptor
    • Yayon A, Klagsbrun M, Esko D, Leder P and Ornitz DM (1991) Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptor. Cell 64:841-848
    • (1991) Cell , vol.64 , pp. 841-848
    • Yayon, A.1    Klagsbrun, M.2    Esko, D.3    Leder, P.4    Ornitz, D.M.5
  • 42
    • 0026472599 scopus 로고
    • Inhibition by pentosan polysulfate (PPS) of heparin-binding growth factors released from tumor cells and blockage by PPS of tumor growth in animals
    • Zugmaier G, Lippman ME and Wellstein A (1992) Inhibition by pentosan polysulfate (PPS) of heparin-binding growth factors released from tumor cells and blockage by PPS of tumor growth in animals. J Natl Cancer Inst 84:1716-1724.
    • (1992) J Natl Cancer Inst , vol.84 , pp. 1716-1724
    • Zugmaier, G.1    Lippman, M.E.2    Wellstein, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.