Insulin-resistant heart exhibits a mitochondrial biogenic response driven by the peroxisome proliferator-activated receptor-α/PGC-1α gene regulatory pathway

Circulation

Volumn 115, Issue 7, 2007, Pages 909-917

  Duncan, Jennifer G ^a   Fong, Juliet L ^a   Medeiros, Denis M ^b   Finck, Brian N ^a   Kelly, Daniel P ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b KANSAS STATE UNIVERSITY   (United States)

Author keywords

Cardiomyopathy; Diabetes mellitus; Metabolism; Mitochondria

Indexed keywords

DIPHTHERIA TOXIN; MITOCHONDRIAL DNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOGENESIS; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; GENE EXPRESSION; HEART MUSCLE CELL; INSULIN RESISTANCE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRANSGENIC MOUSE; WILD TYPE;

ANIMALS; DIABETES MELLITUS, TYPE 2; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; HEART DISEASES; INSULIN RESISTANCE; MALE; MICE; MICE, TRANSGENIC; MITOCHONDRIA, HEART; PPAR ALPHA; TRANSCRIPTION FACTORS;

EID: 33847110733     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.106.662296     Document Type: Article

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