Toxicogenomic responses in rainbow trout (Oncorhynchus mykiss) hepatocytes exposed to model chemicals and a synthetic mixture

Aquatic Toxicology

Volumn 81, Issue 3, 2007, Pages 293-303

  Finne, E F ^a,b   Cooper, G A ^c   Koop, B F ^c   Hylland, K ^a,b   Tollefsen, K E ^a  

^a NORWEGIAN INSTITUTE FOR WATER RESEARCH   (Norway)

^b UNIVERSITY OF OSLO   (Norway)

^c UNIVERSITY OF VICTORIA   (Canada)

Author keywords

Dioxin; DNA damage; Endocrine disruption; Gene expression; Genomics; Microarray; Mixture toxicity; Oxidative stress; Rainbow trout

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; 4 NITROQUINOLINE 1 OXIDE; BIOLOGICAL MARKER; COMPLEMENTARY DNA; DEOXYRIBONUCLEASE; ETHINYLESTRADIOL; FLUORESCENT DYE; PARAQUAT; RNA;

CHEMICAL POLLUTANT; DIOXIN; DNA; ECOTOXICOLOGY; ENDOCRINE DISRUPTOR; GENE EXPRESSION; GENETIC ANALYSIS; GENETIC MARKER; GENOMICS; OXIDATION; POLLUTION EXPOSURE; SALMONID; TOXICITY TEST;

ANIMAL CELL; ANIMAL TISSUE; AQUATIC ENVIRONMENT; ARTICLE; CHEMICAL MUTAGENESIS; CONTROLLED STUDY; CYP1A GENE; DNA DAMAGE; DNA MICROARRAY; DNA RNA HYBRIDIZATION; DNA SYNTHESIS; ECOTOXICOLOGY; ENVIRONMENTAL EXPOSURE; FLUORESCENCE ANALYSIS; GCS GENE; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GR GENE; IN VITRO STUDY; LIVER CELL CULTURE; LIVER TOXICITY; MALE; MARKER GENE; MICROARRAY ANALYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAINBOW TROUT; REAL TIME POLYMERASE CHAIN REACTION; RNA EXTRACTION; SEQUENCE ANALYSIS; TOXICOGENETICS; TRANSCRIPTOMICS; UDP GT GENE; UNINDEXED SEQUENCE; VALIDATION PROCESS; VEP GENE; VTG GENE;

ANIMALS; DNA PRIMERS; DOWN-REGULATION; DRUG SYNERGISM; ETHINYL ESTRADIOL; GENE EXPRESSION; GENE EXPRESSION PROFILING; HEPATOCYTES; HETEROCYCLIC COMPOUNDS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; ONCORHYNCHUS MYKISS; PRINCIPAL COMPONENT ANALYSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TOXICOGENETICS; UP-REGULATION; WATER POLLUTANTS, CHEMICAL;

ONCORHYNCHUS MYKISS; SALMONIDAE;

EID: 33847078849     PISSN: 0166445X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.aquatox.2006.12.010     Document Type: Article

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