Btk regulates multiple stages in the development and survival of B-1 cells

Molecular Immunology

Volumn 44, Issue 10, 2007, Pages 2719-2728

  Contreras, Cristina M ^a   Halcomb, Kristina E ^a   Randle, Lindsey ^a   Hinman, Rochelle M ^a   Gutierrez, Toni ^a   Clarke, Stephen H ^b   Satterthwaite, Anne B ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

B cell development; BCR signaling; IL 10; Lyn; Phosphatidylcholine

Indexed keywords

B LYMPHOCYTE ANTIGEN; BRUTON TYROSINE KINASE; INTERLEUKIN 10; PHOSPHATIDYLCHOLINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; B LYMPHOCYTE; CELL DIFFERENTIATION; CELL MATURATION; CELL SURVIVAL; CONTROLLED STUDY; CROSS LINKING; ENZYME REGULATION; MOUSE; MUTATION; NONHUMAN; PERITONEUM; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SENSITIVITY ANALYSIS; SPLEEN CELL; TRANSGENIC MOUSE;

ANIMALS; B-LYMPHOCYTES; CELL LINEAGE; CELL SURVIVAL; MICE; MICE, INBRED STRAINS; MICE, TRANSGENIC; PERITONEUM; PROTEIN-TYROSINE KINASES; RECEPTORS, ANTIGEN, B-CELL; RECEPTORS, IGE;

MUS; MUS MUSCULUS;

EID: 33846903332     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2006.11.023     Document Type: Article

References (50)

1. Ansel K.M., Harris R.B., and Cyster J.G. CXCL13 is required for B1 cell homing, natural antibody production, and body cavity immunity. Immunity 16 (2002) 67-76
2. Arnold L.W., Pennell C.A., McCray S.K., and Clarke S.H. Development of B-1 cells: segregation of phosphatidyl choline-specific B cells to the B-1 population occurs after immunoglobulin gene expression. J. Exp. Med. 179 (1994) 1585-1595
3. Arnold L.W., McCray S.K., Tatu C., and Clarke S.H. Identification of a precursor to phosphatidyl choline-specific B-1 cells suggesting that B-1 cells differentiate from splenic conventional B cells in vivo: cyclosporin A blocks differentiation to B-1. J. Immunol. 164 (2000) 2924-2930
4. Baumgarth N., Herman O.C., Jager G.C., Brown L.E., Herzenberg L.A., and Chen J. B-1 and B-2 cell-derived immunoglobulin M antibodies are nonredundant components of the protective response to influenza virus infection. J. Exp. Med. 192 (2000) 271-280
5. Chan V.W., Meng F., Soriano P., DeFranco A.L., and Lowell C.A. Characterization of the B lymphocyte populations in Lyn-deficient mice and the role of Lyn in signal initiation and down-regulation. Immunity 7 (1997) 69-81
6. Chumley M.J., Dal Porto J.M., Kawaguchi S., Cambier J.C., Nemazee D., and Hardy R.R. A VH11V kappa 9 B cell antigen receptor drives generation of CD5+ B cells both in vivo and in vitro. J. Immunol. 164 (2000) 4586-4593
7. Chumley M.J., Dal Porto J.M., and Cambier J.C. The unique antigen receptor signaling phenotype of B-1 cells is influenced by locale but induced by antigen. J. Immunol. 169 (2002) 1735-1743
8. Clarke S.H., and Arnold L.W. B-1 cell development: evidence for an uncommitted immunoglobulin (Ig)M+ B cell precursor in B-1 cell differentiation. J. Exp. Med. 187 (1998) 1325-1334
9. Desiderio S. Role of Btk in B cell development and signaling. Curr. Opin. Immunol. 9 (1997) 534-540
10. Fluckiger A.C., Li Z., Kato R.M., Wahl M.I., Ochs H.D., Longnecker R., Kinet J.P., Witte O.N., Scharenberg A.M., and Rawlings D.J. Btk/Tec kinases regulate sustained increases in intracellular Ca2+ following B-cell receptor activation. EMBO J. 17 (1998) 1973-1985
11. Gary-Gouy H., Harriague J., Bismuth G., Platzer C., Schmitt C., and Dalloul A.H. Human CD5 promotes B-cell survival through stimulation of autocrine IL-10 production. Blood 100 (2002) 4537-4543
12. Go N.F., Castle B.E., Barrett R., Kastelein R., Dang W., Mossman T.R., Moore K.W., and Howard M. Interleukin 10, a novel B cell stimulatory factor: unresponsiveness of X chromosome-linked immunodeficiency B cells. J. Exp. Med. 172 (1990) 1625-1631
13. Harder K.W., Parsons L.M., Armes J., Evans N., Kountouri N., Clark R., Quilici C., Grail D., Hodgson G.S., Dunn A.R., and Hibbs M.L. Gain- and loss-of-function Lyn mutant mice define a critical inhibitory role for Lyn in the myeloid lineage. Immunity 15 (2001) 603-615
14. Hardy R.R., and Hayakawa K. B cell development pathways. Annu. Rev. Immunol. 19 (2001) 595-621
15. Hasegawa M., Fujimoto M., Poe J.C., Steeber D.A., Lowell C.A., and Tedder T.F. A CD19-dependent signaling pathway regulates autoimmunity in Lyn-deficient mice. J. Immunol. 167 (2001) 2469-2478
16. Hayakawa K., Hardy R.R., Herzenberg L.A., and Herzenberg L.A. Progenitors for Ly-1 B cells are distinct from progenitors for other B cells. J. Exp. Med. 161 (1985) 1554-1568
17. Hayakawa K., Asano M., Shinton S.A., Gui M., Allman D., Stewart C.L., Silver J., and Hardy R.R. Positive selection of natural autoreactive B cells. Science 285 (1999) 113-116
18. Ishida H., Hastings R., Kearney J., and Howard M. Continuous anti-interleukin 10 antibody administration depletes mice of Ly-1 B cells but not conventional B cells. J. Exp. Med. 175 (1992) 1213-1220
19. Ishida D., Su L., Tamura A., Katayama Y., Kawai Y., Wang S.-F., Taniwaki M., Hamazaki Y., Hattori M., and Minato N. Rap1 signal controls B cell receptor repertoire and generation of self-reactive B1a cells. Immunity 24 (2006) 417-427
20. Khan W.N. Regulation of B lymphocyte development and activation by Bruton's tyrosine kinase. Immunol. Res. 23 (2001) 147-156
21. Koike M., Kikuchi Y., Tominaga A., Takaki S., Akagi K., Miyazaki J., Yamamura K., and Takatsu K. Defective IL-5-receptor-mediated signaling in B cells of X-linked immunodeficient mice. Int. Immunol. 7 (1995) 21-30
22. Kopf M., Brombacher F., Hodgkin P.D., Ramsay A.J., Milbourne E.A., Dai W.J., Ovington K.S., Behm C.A., Koheler G., Young I.G., and Matthaie K.I. IL-5-deficient mice have a developmental defect in CD5+ B-1 cells and lack eosinophilia but have normal antibody and cytotoxic T cell responses. Immunity 4 (1996) 15-24
23. Kroese F.G., Butcher E.C., Stall A.M., Lalor P.A., Adams S., and Herzenberg L.A. Many of the IgA producing plasma cells in murine gut are derived from self-replenishing precursors in the peritoneal cavity. Int. Immunol. 1 (1989) 75-84
24. Lam K.P., and Rajewsky K. B cell antigen receptor specificity and surface density together determine B-1 versus B-2 cell development. J. Exp. Med. 190 (1999) 471-477
25. Li Y.S., Hayakawa K., and Hardy R.R. The regulated expression of B lineage associated genes during B cell differentiation in bone marrow and fetal liver. J. Exp. Med. 178 (1993) 951-960
26. Loder F., Mutschler B., Ray R.J., Paige C.J., Sideras P., Torres R., Lamers M.C., and Carsetti R. B cell development in the spleen takes place in discrete steps and is determined by the quality of B cell receptor-derived signals. J. Exp. Med. 190 (1999) 75-89
27. Martin F., and Kearney J.F. B1 cells: similarities and differences with other B cell subsets. Curr. Opin. Immunol. 13 (2001) 195-201
28. Martin F., Oliver A.M., and Kearney J.F. Marginal zone and B1 B cells unite in the early response against T-independent blood-borne particulate antigens. Immunity 14 (2001) 617-629
29. McLeod S.J., Shum A.J., Lee R.L., Takei F., and Gold M.R. The Rap GTPases regulate integrin-mediated adhesion, cell spreading, actin polymerization, and Pyk2 tyrosine phosphorylation in B lymphocytes. J. Biol. Chem. 279 (2004) 12009-12019
30. Montecino-Rodriguez R., Leathers H., and Dorshkind K. Identification of a B-1 B cell-specified progenitor. Nat. Immunol. 7 (2006) 293-301
31. Murakami M., Yoshioka H., Shirai T., Tsubata T., and Honjo T. Prevention of autoimmune symptoms in autoimmune-prone mice by elimination of B-1 cells. Int. Immunol. 7 (1995) 877-882
32. Nishizumi H., Taniuchi I., Yamanashi Y., Kitamura D., Ilic D., Mori S., Watanabe T., and Yamamoto T. Impaired proliferation of peripheral B cells and indication of autoimmune disease in lyn-deficient mice. Immunity 3 (1995) 549-560
33. O'Garra A., Chang R., Go N., Hastings R., Haughton G., and Howard M. Ly-1 B (B-1) cells are the main source of B cell-derived interleukin 10. Eur. J. Immunol. 22 (1992) 711-717
34. Paciorkowski N., Porte P., Shultz L.D., and Rajan T.V. B1 B lymphocytes play a critical role in host protection against lymphatic filarial parasites. J. Exp. Med. 191 (2000) 731-736
35. Reap E.A., Sobel E.S., Cohen P.L., and Eisenberg R.A. Conventional B cells, not B-1 cells, are responsible for producing autoantibodies in lpr mice. J. Exp. Med. 177 (1993) 69-78
36. Rigley K.P., Harnett M.M., Phillips R.J., and Klaus G.G. Analysis of signaling via surface immunoglobulin receptors on B cells from CBA/N mice. Eur. J. Immunol. 19 (1989) 2081-2086
37. Rothstein T.L. Cutting edge commentary: two B-1 or not to be one. J. Immunol. 168 (2002) 4257-4261
38. Satterthwaite A.B., Cheroutre H., Khan W.N., Sideras P., and Witte O.N. Btk dosage determines sensitivity to B cell antigen receptor cross-linking. Proc. Natl. Acad. Sci. U.S.A. 94 (1997) 13152-13157
39. Satterthwaite A.B., Lowell C.A., Khan W.N., Sideras P., Alt F.W., and Witte O.N. Independent and opposing roles for Btk and lyn in B and myeloid signaling pathways. J. Exp. Med. 188 (1998) 833-844
40. Satterthwaite A.B., and Witte O.N. The role of Bruton's tyrosine kinase in B-cell development and function: a genetic perspective. Immunol. Rev. 175 (2000) 120-127
41. Spaargaren M., Beuling E.A., Rurup M.L., Meijer H.P., Klok M.D., Middendorp S., Hendriks R.W., and Pals S.T. The B cell antigen receptor controls integrin activity through Btk and PLCγ2. J. Exp. Med. 198 (2003) 1539-1550
42. Takeshita H., Taniuchi I., Kato J., and Watanabe T. Abrogation of autoimmune disease in Lyn-deficient mice by the mutation of the Btk gene. Int. Immunol. 10 (1998) 435-444
43. Tatu C., Ye J., Arnold L.W., and Clarke S.H. Selection at multiple checkpoints focuses V(H)12 B cell differentiation toward a single B-1 cell specificity. J. Exp. Med. 190 (1999) 903-914
44. Watanabe N., Nisitani S., Ikuta K., Suzuki M., Chiba T., and Honjo T. Expression levels of B cell surface immunoglobulin regulate efficiency of allelic exclusion and size of autoreactive B-1 cell compartment. J. Exp. Med. 190 (1999) 461-469
45. Whyburn L.R., Halcomb K.E., Contreras C.M., Lowell C.A., Witte O.N., and Satterthwaite A.B. Reduced dosage of Bruton's tyrosine kinase uncouples B cell hyperresponsiveness from autoimmunity in Lyn-/- mice. J. Immunol. 171 (2003) 1850-1858
46. Witt C.M., Won W.J., Hurez V., and Klug C.A. Notch2 haploinsufficiency results in diminished B1 B cells and a severe reduction in marginal zone B cells. J. Immunol. 171 (2003) 2783-2788
47. Witt C.M., Hurez V., Swindle C.S., Hamada Y., and Klug C.A. Activated Notch2 potentiates CD8 lineage maturation and promotes the selective development of B1 B cells. Mol. Cell. Biol. 23 (2003) 8637-8650
48. Wong S.C., Chew W.K., Tan J.E., Melendez A.J., Francis E., and Lam K.P. Peritoneal CD5+ B-1 cells have signaling properties similar to tolerant B cells. J. Biol. Chem. 277 (2002) 30707-30715
49. Wortis H.H., and Berland R. Cutting edge commentary: origins of B-1 cells. J. Immunol. 166 (2001) 2163-2166
50. Yoshida T., Ikuta K., Sugaya H., Maki K., Takagi M., Kanazawa H., Sunaga S., Kinashi T., Yoshimuar K., Miyazaki J., Takaki S., and Takatsu K. Defective B-1 cell development and impaired immunity against Angiostrongylus cantonensis in IL-5R alpha-deficient mice. Immunity 4 (1996) 483-494