-
1
-
-
0027954044
-
Mutations of the VHL tumour suppressor gene in renal carcinoma
-
Gnarra JR, Tory K, Weng Y, et al. Mutations of the VHL tumour suppressor gene in renal carcinoma. Nat Genet 1994;7:85-90.
-
(1994)
Nat Genet
, vol.7
, pp. 85-90
-
-
Gnarra, J.R.1
Tory, K.2
Weng, Y.3
-
2
-
-
0028235907
-
Frequent somatic mutations and loss of heterozygosity of the von Hippel-Lindau tumor suppressor gene in primary human renal cell carcinomas
-
Shuin T, Kondo K, Torigoe S, et al. Frequent somatic mutations and loss of heterozygosity of the von Hippel-Lindau tumor suppressor gene in primary human renal cell carcinomas. Cancer Res 1994;54:2852-5.
-
(1994)
Cancer Res
, vol.54
, pp. 2852-2855
-
-
Shuin, T.1
Kondo, K.2
Torigoe, S.3
-
3
-
-
0028072991
-
Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma
-
Herman JG, Latif F, Weng Y, et al. Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma. Proc Natl Acad Sci U S A 1994;91:9700-4.
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 9700-9704
-
-
Herman, J.G.1
Latif, F.2
Weng, Y.3
-
4
-
-
0028897420
-
Genetics of renal-cell carcinoma and evidence for a critical role for von Hippel-Lindau in renal tumorigenesis
-
Gnarra JR, Lerman MI, Zbar B, Linehan WM. Genetics of renal-cell carcinoma and evidence for a critical role for von Hippel-Lindau in renal tumorigenesis. Semin Oncol 1995;22:3-8.
-
(1995)
Semin Oncol
, vol.22
, pp. 3-8
-
-
Gnarra, J.R.1
Lerman, M.I.2
Zbar, B.3
Linehan, W.M.4
-
5
-
-
0036528246
-
Inhibition of HIF is necessary for tumor suppression by the von Hippel-Lindau protein
-
Kondo K, Klco J, Nakamura E, Lechpammer M, Kaelin WG, Jr. Inhibition of HIF is necessary for tumor suppression by the von Hippel-Lindau protein. Cancer Cell 2002;1:237-46.
-
(2002)
Cancer Cell
, vol.1
, pp. 237-246
-
-
Kondo, K.1
Klco, J.2
Nakamura, E.3
Lechpammer, M.4
Kaelin Jr., W.G.5
-
6
-
-
0030781576
-
Sporadic pheochromocytomas are rarely associated with germline mutations in the vhl tumor suppressor gene or the ret protooncogene
-
Brauch H, Hoeppner W, Jahnig H, et al. Sporadic pheochromocytomas are rarely associated with germline mutations in the vhl tumor suppressor gene or the ret protooncogene. J Clin Endocrinol Metab 1997;82:4101-4.
-
(1997)
J Clin Endocrinol Metab
, vol.82
, pp. 4101-4104
-
-
Brauch, H.1
Hoeppner, W.2
Jahnig, H.3
-
7
-
-
0031776704
-
Inactivation of the von Hippel-Lindau (VHL) tumour suppressor gene and allelic losses at chromosome arm 3p in primary renal cell carcinoma: Evidence for a VHL-independent pathway in clear cell renal tumourigenesis
-
Clifford SC, Prowse AH, Affara NA, Buys CH, Maher ER. Inactivation of the von Hippel-Lindau (VHL) tumour suppressor gene and allelic losses at chromosome arm 3p in primary renal cell carcinoma: evidence for a VHL-independent pathway in clear cell renal tumourigenesis. Genes Chromosomes Cancer 1998;22:200-9.
-
(1998)
Genes Chromosomes Cancer
, vol.22
, pp. 200-209
-
-
Clifford, S.C.1
Prowse, A.H.2
Affara, N.A.3
Buys, C.H.4
Maher, E.R.5
-
8
-
-
18344396226
-
Comprehensive mutational analysis of the VHL gene in sporadic renal cell carcinoma: Relationship to clinicopathological parameters
-
Kondo K, Yao M, Yoshida M, et al. Comprehensive mutational analysis of the VHL gene in sporadic renal cell carcinoma: relationship to clinicopathological parameters. Genes Chromosomes Cancer 2002;34:58-68.
-
(2002)
Genes Chromosomes Cancer
, vol.34
, pp. 58-68
-
-
Kondo, K.1
Yao, M.2
Yoshida, M.3
-
9
-
-
0029944971
-
Mutation of the VHL gene is associated exclusively with the development of non-papillary renal cell carcinomas
-
Kenck C, Wilhelm M, Bugert P, Staehler G, Kovacs G. Mutation of the VHL gene is associated exclusively with the development of non-papillary renal cell carcinomas. J Pathol 1996;179:157-61.
-
(1996)
J Pathol
, vol.179
, pp. 157-161
-
-
Kenck, C.1
Wilhelm, M.2
Bugert, P.3
Staehler, G.4
Kovacs, G.5
-
10
-
-
0029147430
-
Binding of the von Hippel-Lindau tumor suppressor protein to elongin B and C
-
Kibel A, Iliopoulos O, DeCaprio JA, Kaelin WG, Jr. Binding of the von Hippel-Lindau tumor suppressor protein to elongin B and C. Science 1995;269:1444-6.
-
(1995)
Science
, vol.269
, pp. 1444-1446
-
-
Kibel, A.1
Iliopoulos, O.2
DeCaprio, J.A.3
Kaelin Jr., W.G.4
-
11
-
-
0033587146
-
The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
-
Maxwell PH, Wiesener MS, Chang GW, et al. The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis. Nature 1999;399:271-5.
-
(1999)
Nature
, vol.399
, pp. 271-275
-
-
Maxwell, P.H.1
Wiesener, M.S.2
Chang, G.W.3
-
12
-
-
0034682783
-
Hypoxia inducible factor-α binding and ubiquitylation by the von Hippel-Lindau tumor suppressor protein
-
Cockman ME, Masson N, Mole DR, et al. Hypoxia inducible factor-α binding and ubiquitylation by the von Hippel-Lindau tumor suppressor protein. J Biol Chem 2000;275:25733-41.
-
(2000)
J Biol Chem
, vol.275
, pp. 25733-25741
-
-
Cockman, M.E.1
Masson, N.2
Mole, D.R.3
-
14
-
-
0037326037
-
The von Hippel-Lindau tumor suppressor, hypoxia-inducible factor-1 (HIF-1) degradation, and cancer pathogenesis
-
Pugh CW, Ratcliffe PJ. The von Hippel-Lindau tumor suppressor, hypoxia-inducible factor-1 (HIF-1) degradation, and cancer pathogenesis. Semin Cancer Biol 2003;13:83-9.
-
(2003)
Semin Cancer Biol
, vol.13
, pp. 83-89
-
-
Pugh, C.W.1
Ratcliffe, P.J.2
-
16
-
-
0029785321
-
Negative regulation of hypoxia-inducible genes by the von Hippel-Lindau protein
-
Iliopoulos O, Levy AP, Jiang C, Kaelin WG, Jr., Goldberg MA. Negative regulation of hypoxia-inducible genes by the von Hippel-Lindau protein. Proc Natl Acad Sci U S A 1996;93:10595-9.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 10595-10599
-
-
Iliopoulos, O.1
Levy, A.P.2
Jiang, C.3
Kaelin Jr., W.G.4
Goldberg, M.A.5
-
17
-
-
33646248422
-
Differential regulation of the transcriptional activities of hypoxia-inducible factor 1α (HIF-1α) and HIF-2α in stem cells
-
Hu CJ, Iyer S, Sataur A, Covello KL, Chodosh LA, Simon MC. Differential regulation of the transcriptional activities of hypoxia-inducible factor 1α (HIF-1α) and HIF-2α in stem cells. Mol Cell Biol 2006;26:3514-26.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 3514-3526
-
-
Hu, C.J.1
Iyer, S.2
Sataur, A.3
Covello, K.L.4
Chodosh, L.A.5
Simon, M.C.6
-
18
-
-
0024818355
-
Vascular endothelial growth factor is a secreted angiogenic mitogen
-
Leung DW, Cachianes G, Kuang WJ, Goeddel DV, Ferrara N. Vascular endothelial growth factor is a secreted angiogenic mitogen. Science 1989;246:1306-9.
-
(1989)
Science
, vol.246
, pp. 1306-1309
-
-
Leung, D.W.1
Cachianes, G.2
Kuang, W.J.3
Goeddel, D.V.4
Ferrara, N.5
-
19
-
-
0024801035
-
Vascular permeability factor, an endothelial cell mitogen related to PDGF
-
Keck PJ, Hauser SD, Krivi G, et al. Vascular permeability factor, an endothelial cell mitogen related to PDGF. Science 1989;246:1309-12.
-
(1989)
Science
, vol.246
, pp. 1309-1312
-
-
Keck, P.J.1
Hauser, S.D.2
Krivi, G.3
-
20
-
-
0033693293
-
Vascular endothelial growth factor (VEGF) modulation by targeting hypoxia-inducible factor-1α→ hypoxia response element→ VEGF cascade differentially regulates vascular response and growth rate in tumors
-
Tsuzuki Y, Fukumura D, Oosthuyse B, Koike C, Carmeliet P, Jain RK. Vascular endothelial growth factor (VEGF) modulation by targeting hypoxia-inducible factor-1α→ hypoxia response element→ VEGF cascade differentially regulates vascular response and growth rate in tumors. Cancer Res 2000;60:6248-52.
-
(2000)
Cancer Res
, vol.60
, pp. 6248-6252
-
-
Tsuzuki, Y.1
Fukumura, D.2
Oosthuyse, B.3
Koike, C.4
Carmeliet, P.5
Jain, R.K.6
-
21
-
-
0026485002
-
Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis
-
Shweiki D, Itin A, Soffer D, Keshet E. Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis. Nature 1992;359:843-5.
-
(1992)
Nature
, vol.359
, pp. 843-845
-
-
Shweiki, D.1
Itin, A.2
Soffer, D.3
Keshet, E.4
-
22
-
-
0025999033
-
The human gene for vascular endothelial growth factor: Multiple protein forms are encoded through alternative exon splicing
-
Tischer E, Mitchell R, Hartman T, et al. The human gene for vascular endothelial growth factor: multiple protein forms are encoded through alternative exon splicing. J Biol Chem 1991;266:11947-54.
-
(1991)
J Biol Chem
, vol.266
, pp. 11947-11954
-
-
Tischer, E.1
Mitchell, R.2
Hartman, T.3
-
23
-
-
0024384470
-
Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells
-
Ferrara N, Henzel WJ. Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells. Biochem Biophys Res Commun 1989;161:851-8.
-
(1989)
Biochem Biophys Res Commun
, vol.161
, pp. 851-858
-
-
Ferrara, N.1
Henzel, W.J.2
-
24
-
-
0034636296
-
Formation of endothelial cell networks
-
Helmlinger G, Endo M, Ferrara N, Hlatky L, Jain RK. Formation of endothelial cell networks. Nature 2000;405:139-41.
-
(2000)
Nature
, vol.405
, pp. 139-141
-
-
Helmlinger, G.1
Endo, M.2
Ferrara, N.3
Hlatky, L.4
Jain, R.K.5
-
25
-
-
0023039225
-
A highly conserved vascular permeability factor secreted by a variety of human and rodent tumor cell lines
-
Senger DR, Perruzzi CA, Feder J, Dvorak HF. A highly conserved vascular permeability factor secreted by a variety of human and rodent tumor cell lines. Cancer Res 1986;46:5629-32.
-
(1986)
Cancer Res
, vol.46
, pp. 5629-5632
-
-
Senger, D.R.1
Perruzzi, C.A.2
Feder, J.3
Dvorak, H.F.4
-
26
-
-
0027453084
-
Characterization of the increase in vascular permeability induced by vascular permeability factor in vivo
-
Collins PD, Connolly DT, Williams TJ. Characterization of the increase in vascular permeability induced by vascular permeability factor in vivo. Br J Pharmacol 1993;109:195-9.
-
(1993)
Br J Pharmacol
, vol.109
, pp. 195-199
-
-
Collins, P.D.1
Connolly, D.T.2
Williams, T.J.3
-
27
-
-
0029004025
-
Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis
-
Dvorak HF, Brown LF, Detmar M, Dvorak AM. Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis. Am J Pathol 1995;146:1029-39.
-
(1995)
Am J Pathol
, vol.146
, pp. 1029-1039
-
-
Dvorak, H.F.1
Brown, L.F.2
Detmar, M.3
Dvorak, A.M.4
-
28
-
-
0029010434
-
Increased microvascular permeability and endothelial fenestration induced by vascular endothelial growth factor
-
Roberts WG, Palade GE. Increased microvascular permeability and endothelial fenestration induced by vascular endothelial growth factor. J Cell Sci 1995;108:2369-79.
-
(1995)
J Cell Sci
, vol.108
, pp. 2369-2379
-
-
Roberts, W.G.1
Palade, G.E.2
-
29
-
-
0030444567
-
VEGF induces NO-dependent hyperpermeability in coronary venules
-
Wu HM, Huang Q, Yuan Y, Granger HJ. VEGF induces NO-dependent hyperpermeability in coronary venules. Am J Physiol 1996;271:H2735-9.
-
(1996)
Am J Physiol
, vol.271
-
-
Wu, H.M.1
Huang, Q.2
Yuan, Y.3
Granger, H.J.4
-
30
-
-
0031836159
-
VEGF induces hyperpermeability by a direct action on endothelial cells
-
Hippenstiel S, Krull M, Ikemann A, Risau W, Clauss M, Suttorp N. VEGF induces hyperpermeability by a direct action on endothelial cells. Am J Physiol 1998;274:L678-84.
-
(1998)
Am J Physiol
, vol.274
-
-
Hippenstiel, S.1
Krull, M.2
Ikemann, A.3
Risau, W.4
Clauss, M.5
Suttorp, N.6
-
31
-
-
0034754014
-
VEGF increases permeability of the endothelial cell monolayer by activation of PKB/akt, endothelial nitric-oxide synthase, and MAP kinase pathways
-
Lal BK, Varma S, Pappas PJ, Hobson RW II, Duran WN. VEGF increases permeability of the endothelial cell monolayer by activation of PKB/akt, endothelial nitric-oxide synthase, and MAP kinase pathways. Microvasc Res 2001;62:252-62.
-
(2001)
Microvasc Res
, vol.62
, pp. 252-262
-
-
Lal, B.K.1
Varma, S.2
Pappas, P.J.3
Hobson II, R.W.4
Duran, W.N.5
-
32
-
-
0033146795
-
Vascular endothelial growth factor and microvascular permeability
-
Bates DO, Lodwick D, Williams B. Vascular endothelial growth factor and microvascular permeability. Microcirculation 1999;6:83-96.
-
(1999)
Microcirculation
, vol.6
, pp. 83-96
-
-
Bates, D.O.1
Lodwick, D.2
Williams, B.3
-
33
-
-
0024961105
-
Angiogenesis: Successful growth of tumours
-
Ross R. Angiogenesis: successful growth of tumours. Nature 1989;339:16-7.
-
(1989)
Nature
, vol.339
, pp. 16-17
-
-
Ross, R.1
-
34
-
-
0028275909
-
Microvessel count and cerebrospinal fluid basic fibroblast growth factor in children with brain tumours
-
Li VW, Folkerth RD, Watanabe H, et al. Microvessel count and cerebrospinal fluid basic fibroblast growth factor in children with brain tumours. Lancet 1994;344:82-6.
-
(1994)
Lancet
, vol.344
, pp. 82-86
-
-
Li, V.W.1
Folkerth, R.D.2
Watanabe, H.3
-
35
-
-
0031841108
-
Basic fibroblast growth factor and vascular endothelial growth factor in sera from non-small cell lung cancer patients
-
Brattstrom D, Bergqvist M, Larsson A, et al. Basic fibroblast growth factor and vascular endothelial growth factor in sera from non-small cell lung cancer patients. Anticancer Res 1998;18:1123-7.
-
(1998)
Anticancer Res
, vol.18
, pp. 1123-1127
-
-
Brattstrom, D.1
Bergqvist, M.2
Larsson, A.3
-
36
-
-
9344236065
-
Concentrations of vascular endothelial growth factor in the sera of normal controls and cancer patients
-
Yamamoto Y, Toi M, Kondo S, et al. Concentrations of vascular endothelial growth factor in the sera of normal controls and cancer patients. Clin Cancer Res 1996;2:821-6.
-
(1996)
Clin Cancer Res
, vol.2
, pp. 821-826
-
-
Yamamoto, Y.1
Toi, M.2
Kondo, S.3
-
37
-
-
0031942430
-
High pre-treatment serum level of vascular endothelial growth factor (VEGF) is associated with poor outcome in small-cell lung cancer
-
Salven P, Ruotsalainen T, Mattson K, Joensuu H. High pre-treatment serum level of vascular endothelial growth factor (VEGF) is associated with poor outcome in small-cell lung cancer. Int J Cancer 1998;79:144-6.
-
(1998)
Int J Cancer
, vol.79
, pp. 144-146
-
-
Salven, P.1
Ruotsalainen, T.2
Mattson, K.3
Joensuu, H.4
-
38
-
-
0031032073
-
Prognostic significance of vascular endothelial growth factor protein in node-negative breast carcinoma
-
Gasparini G, Toi M, Gion M, et al. Prognostic significance of vascular endothelial growth factor protein in node-negative breast carcinoma. J Natl Cancer Inst 1997;89:139-47.
-
(1997)
J Natl Cancer Inst
, vol.89
, pp. 139-147
-
-
Gasparini, G.1
Toi, M.2
Gion, M.3
-
39
-
-
0029155712
-
Vascular permeability factor (vascular endothelial growth factor) expression and angiogenesis in cervical neoplasia
-
Guidi AJ, Abu-Jawdeh G, Berse B, et al. Vascular permeability factor (vascular endothelial growth factor) expression and angiogenesis in cervical neoplasia. J Natl Cancer Inst 1995;87:1237-45.
-
(1995)
J Natl Cancer Inst
, vol.87
, pp. 1237-1245
-
-
Guidi, A.J.1
Abu-Jawdeh, G.2
Berse, B.3
-
40
-
-
0030856731
-
Humanization of an anti-vascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders
-
Presta LG, Chen H, O'Connor SJ, et al. Humanization of an anti-vascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders. Cancer Res 1997;57:4593-9.
-
(1997)
Cancer Res
, vol.57
, pp. 4593-4599
-
-
Presta, L.G.1
Chen, H.2
O'Connor, S.J.3
-
41
-
-
20044375603
-
Biological activity of bevacizumab, a humanized anti-VEGF antibody in vitro
-
Wang Y, Fei D, Vanderlaan M, Song A. Biological activity of bevacizumab, a humanized anti-VEGF antibody in vitro. Angiogenesis 2004;7:335-45.
-
(2004)
Angiogenesis
, vol.7
, pp. 335-345
-
-
Wang, Y.1
Fei, D.2
Vanderlaan, M.3
Song, A.4
-
42
-
-
13444278498
-
Pharmacology and pharmacodynamics of bevacizumab as monotherapy or in combination with cytotoxic therapy in preclinical studies
-
Gerber HP, Ferrara N. Pharmacology and pharmacodynamics of bevacizumab as monotherapy or in combination with cytotoxic therapy in preclinical studies. Cancer Res 2005;65:671-80.
-
(2005)
Cancer Res
, vol.65
, pp. 671-680
-
-
Gerber, H.P.1
Ferrara, N.2
-
43
-
-
0033979730
-
Anti-VEGF antibody suppresses primary tumor growth and metastasis in an experimental model of Wilms' tumor
-
discussion 32-33
-
Rowe DH, Huang J, Kayton ML, et al. Anti-VEGF antibody suppresses primary tumor growth and metastasis in an experimental model of Wilms' tumor. J Pediatr Surg 2000;35:30-2; discussion 32-33.
-
(2000)
J Pediatr Surg
, vol.35
, pp. 30-32
-
-
Rowe, D.H.1
Huang, J.2
Kayton, M.L.3
-
44
-
-
0042343801
-
A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer
-
Yang JC, Haworth L, Sherry RM, et al. A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer. N Engl J Med 2003;349:427-34.
-
(2003)
N Engl J Med
, vol.349
, pp. 427-434
-
-
Yang, J.C.1
Haworth, L.2
Sherry, R.M.3
-
45
-
-
0029949160
-
Time-dependent vascular regression and permeability changes in established human tumor xenografts induced by an anti-vascular endothelial growth factor/vascular permeability factor antibody
-
Yuan F, Chen Y, Dellian M, Safabakhsh N, Ferrara N, Jain RK. Time-dependent vascular regression and permeability changes in established human tumor xenografts induced by an anti-vascular endothelial growth factor/vascular permeability factor antibody. Proc Natl Acad Sci U S A 1996;93:14765-70.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 14765-14770
-
-
Yuan, F.1
Chen, Y.2
Dellian, M.3
Safabakhsh, N.4
Ferrara, N.5
Jain, R.K.6
-
46
-
-
4644229716
-
Bevacizumab for patients with metastatic renal cancer: An update
-
Yang JC. Bevacizumab for patients with metastatic renal cancer: an update. Clin Cancer Res 2004;10:6367-70S.
-
(2004)
Clin Cancer Res
, vol.10
-
-
Yang, J.C.1
-
47
-
-
0035394833
-
Acquired resistance to the antitumor effect of epidermal growth factor receptor-blocking antibodies in vivo: A role for altered tumor angiogenesis
-
Viloria-Petit A, Crombet T, Jothy S, et al. Acquired resistance to the antitumor effect of epidermal growth factor receptor-blocking antibodies in vivo: a role for altered tumor angiogenesis. Cancer Res 2001;61:5090-101.
-
(2001)
Cancer Res
, vol.61
, pp. 5090-5101
-
-
Viloria-Petit, A.1
Crombet, T.2
Jothy, S.3
-
48
-
-
30944452354
-
Treatment of metastatic renal cell carcinoma with a combination of bevacizumab and erlotinib
-
Hainsworth JD, Sosman JA, Spigel DR, Edwards DL, Baughman C, Greco A. Treatment of metastatic renal cell carcinoma with a combination of bevacizumab and erlotinib. J Clin Oncol 2005;23:7889-96.
-
(2005)
J Clin Oncol
, vol.23
, pp. 7889-7896
-
-
Hainsworth, J.D.1
Sosman, J.A.2
Spigel, D.R.3
Edwards, D.L.4
Baughman, C.5
Greco, A.6
-
49
-
-
33750938968
-
Bevacizumab with or without erlotinib in metastatic renal cell carcinoma (RCC) [abstract 4523]
-
222s
-
Bukowski RM, Kabbinavar F, Figlin RA, et al. Bevacizumab with or without erlotinib in metastatic renal cell carcinoma (RCC) [abstract 4523]. J Clin Oncol 2006;24:222s.
-
(2006)
J Clin Oncol
, vol.24
-
-
Bukowski, R.M.1
Kabbinavar, F.2
Figlin, R.A.3
-
50
-
-
1942470411
-
Cancer and Leukemia Group B 90206: A randomized phase III trial of interferon-α or interferon-α plus antivascular endothelial growth factor antibody (bevacizumab) in metastatic renal cell carcinoma
-
Rini BI, Halabi S, Taylor J, Small EJ, Schilsky RL. Cancer and Leukemia Group B 90206: a randomized phase III trial of interferon-α or interferon-α plus antivascular endothelial growth factor antibody (bevacizumab) in metastatic renal cell carcinoma. Clin Cancer Res 2004;10:2584-6.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 2584-2586
-
-
Rini, B.I.1
Halabi, S.2
Taylor, J.3
Small, E.J.4
Schilsky, R.L.5
-
51
-
-
0029842830
-
Production of vascular endothelial growth factor by human tumors inhibits the functional maturation of dendritic cells
-
Gabrilovich DI, Chen HL, Girgis KR, et al. Production of vascular endothelial growth factor by human tumors inhibits the functional maturation of dendritic cells. Nat Med 1996;2:1096-103.
-
(1996)
Nat Med
, vol.2
, pp. 1096-1103
-
-
Gabrilovich, D.I.1
Chen, H.L.2
Girgis, K.R.3
-
52
-
-
0032741283
-
Antibodies to vascular endothelial growth factor enhance the efficacy of cancer immunotherapy by improving endogenous dendritic cell function
-
Gabrilovich DI, Ishida T, Nadaf S, Ohm JE, Carbone DP. Antibodies to vascular endothelial growth factor enhance the efficacy of cancer immunotherapy by improving endogenous dendritic cell function. Clin Cancer Res 1999;5:2963-70.
-
(1999)
Clin Cancer Res
, vol.5
, pp. 2963-2970
-
-
Gabrilovich, D.I.1
Ishida, T.2
Nadaf, S.3
Ohm, J.E.4
Carbone, D.P.5
-
53
-
-
33846874348
-
Clinical synergism from combinatorial VEGF signal transduction inhibition in patients with advanced solid tumors: Early results from a phase I study of sorafenib (BAY 43-9006) and bevacizumab
-
Posadas E, Kwitkowski V, Liel M. Clinical synergism from combinatorial VEGF signal transduction inhibition in patients with advanced solid tumors: early results from a phase I study of sorafenib (BAY 43-9006) and bevacizumab. Eur J Cancer Suppl 2005;3:419.
-
(2005)
Eur J Cancer Suppl
, vol.3
, pp. 419
-
-
Posadas, E.1
Kwitkowski, V.2
Liel, M.3
-
55
-
-
7444261960
-
Use of soluble recombinant decoy receptor vascular endothelial growth factor trap (VEGF Trap) to inhibit vascular endothelial growth factor activity
-
Konner J, Dupont J. Use of soluble recombinant decoy receptor vascular endothelial growth factor trap (VEGF Trap) to inhibit vascular endothelial growth factor activity. Clin Colorectal Cancer 2004;4:S81-5.
-
(2004)
Clin Colorectal Cancer
, vol.4
-
-
Konner, J.1
Dupont, J.2
-
56
-
-
0037314709
-
Carbonic anhydrase IX is an independent predictor of survival in advanced renal clear cell carcinoma: Implications for prognosis and therapy
-
Bui MH, Seligson D, Han KR, et al. Carbonic anhydrase IX is an independent predictor of survival in advanced renal clear cell carcinoma: implications for prognosis and therapy. Clin Cancer Res 2003;9:802-11.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 802-811
-
-
Bui, M.H.1
Seligson, D.2
Han, K.R.3
-
57
-
-
7944230804
-
Effects of potent VEGF blockade on experimental Wilms tumor and its persisting vasculature
-
Frischer JS, Huang J, Serur A, et al. Effects of potent VEGF blockade on experimental Wilms tumor and its persisting vasculature. Int J Oncol 2004;25:549-53.
-
(2004)
Int J Oncol
, vol.25
, pp. 549-553
-
-
Frischer, J.S.1
Huang, J.2
Serur, A.3
-
58
-
-
27144465977
-
Phase I and pharmacokinetic study of VEGF Trap administered subcutaneously (sc) to patients with advanced solid malignancies
-
Dupont J, Koutcher J. Phase I and pharmacokinetic study of VEGF Trap administered subcutaneously (sc) to patients with advanced solid malignancies. Proc Am Soc Clin Oncol 2004;23.
-
(2004)
Proc Am Soc Clin Oncol
, pp. 23
-
-
Dupont, J.1
Koutcher, J.2
-
59
-
-
27144467058
-
Safety and pharmacokinetic of intravenous VEGF Trap in a phase I clinical trial of patients with advanced solid tumors
-
Dupont JR, Spriggs D. Safety and pharmacokinetic of intravenous VEGF Trap in a phase I clinical trial of patients with advanced solid tumors. Proc Am Soc Clin Oncol 2005;23.
-
(2005)
Proc Am Soc Clin Oncol
, pp. 23
-
-
Dupont, J.R.1
Spriggs, D.2
-
60
-
-
33846884176
-
Pharmacodynamic indicators of VEGF trap activity in patients with advanced solid tumors
-
Lockhart A, Muruganandham M, Schwartz L. Pharmacodynamic indicators of VEGF trap activity in patients with advanced solid tumors. Clin Cancer Res 2005;11.
-
(2005)
Clin Cancer Res
, pp. 11
-
-
Lockhart, A.1
Muruganandham, M.2
Schwartz, L.3
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