Polymeric anticancer drugs with pH-controlled activation

International Journal of Pharmaceutics

Volumn 277, Issue 1-2, 2004, Pages 63-72

  Ulbrich, K ^a   Etrych, T ^a   Chytil, P ^a   Pechar, M ^a   Jelinkova, M ^b   Rihova, B ^b  

^a INSTITUTE OF MACROMOLECULAR CHEMISTRY   (Czech Republic)

^b INSTITUTE OF MICROBIOLOGY   (Czech Republic)

Author keywords

Antitumor activity; Cytotoxicity; Doxorubicin; Drug targeting; HPMA copolymers; Poly(ethylene glycol)

Indexed keywords

2 IMINOTHIOLANE; 4 AMINOBENZOIC ACID; ALIPHATIC COMPOUND; AMINOCAPROIC ACID; ANTIBODY; BETA ALANINE; CATHEPSIN B; DIGLYCINE; DOXORUBICIN; GLYCYLGLYCINE; GLYCYLPHENYLALANYLLEUCYLGLYCINE; HYDRAZONE DERIVATIVE; IMMUNOGLOBULIN G; LYSOSOME ENZYME; MACROGOL; METHACRYLIC ACID DERIVATIVE; N (2 HYDROXYPROPYL)METHACRYLAMIDE; N SUCCINIMIDYL 3 (2 PYRIDYLDISULFANYL)PROPANOATE; OLIGOPEPTIDE; PEPTIDE DERIVATIVE; POLYMER; PROPIONIC ACID DERIVATIVE; THIOL DERIVATIVE; TRIPEPTIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; CONFERENCE PAPER; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACTIVATION; DRUG CONJUGATION; DRUG PURIFICATION; DRUG RELEASE; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TRANSPORT; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MOUSE; NONHUMAN; PH; POLYMERIZATION; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; T CELL LYMPHOMA; TARGET CELL;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; DOXORUBICIN; HUMANS; HYDROGEN-ION CONCENTRATION; LYMPHOMA, T-CELL; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; NEOPLASMS; POLYMERS; POLYMETHACRYLIC ACIDS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 2442688824     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2003.02.001     Document Type: Conference Paper

References (10)

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