Improvement of physicochemical and biopharmaceutical properties of theophylline by poly(ethylene glycol) conjugates

Farmaco

Volumn 58, Issue 12, 2003, Pages 1307-1312

  Zacchigna, Marina ^a   Di Luca, G ^a   Cateni, F ^a   Zorzet, S ^a   Maurich, V ^a  

^a UNIVERSITY OF TRIESTE   (Italy)

Author keywords

Macromolecular prodrugs; Methoxy poly(ethylene glycol); Poly(ethylene glycol); Theophylline

Indexed keywords

AMINOPHYLLINE; MACROGOL DERIVATIVE; POLY(ETHYLENE GLYCOL) 1500 [7 (HYDROXYMETHYL)THEOPHYLLINE]; POLY(ETHYLENE GLYCOL) 1900 [7 (HYDROXYMETHYL)THEOPHYLLINE]; POLYMER; THEOPHYLLINE; THEOPHYLLINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG CONJUGATION; DRUG DELIVERY SYSTEM; DRUG HYDROLYSIS; DRUG RELEASE; DRUG SOLUBILITY; DRUG STABILITY; DRUG SYNTHESIS; MALE; NONHUMAN; PHYSICAL CHEMISTRY; QUANTITATIVE ANALYSIS; ROOM TEMPERATURE; THERMOSTABILITY;

EID: 0242468135     PISSN: 0014827X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-827X(02)00019-8     Document Type: Article

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