-
1
-
-
0034601112
-
Cellular delivery of antisense oligonucleotides
-
Lebedeva I., Benimetskaya L., Stein C.A., Vilenchik M. Cellular delivery of antisense oligonucleotides. Eur. J. Pharm. Biopharm. 50:(1):2000;101-119.
-
(2000)
Eur. J. Pharm. Biopharm.
, vol.50
, Issue.1
, pp. 101-119
-
-
Lebedeva, I.1
Benimetskaya, L.2
Stein, C.A.3
Vilenchik, M.4
-
2
-
-
0032700656
-
Molecular mechanisms of action of antisense drugs
-
Crooke S.T. Molecular mechanisms of action of antisense drugs. Biochim. Biophys. Acta. 1489:(1):1999;31-44.
-
(1999)
Biochim. Biophys. Acta
, vol.1489
, Issue.1
, pp. 31-44
-
-
Crooke, S.T.1
-
3
-
-
0035287462
-
Responsive polymeric delivery systems
-
Kost J., Langer R. Responsive polymeric delivery systems. Adv. Drug Del. Rev. 46:(1-3):2001;125-148.
-
(2001)
Adv. Drug Del. Rev.
, vol.46
, Issue.1-3
, pp. 125-148
-
-
Kost, J.1
Langer, R.2
-
4
-
-
0032580354
-
Drug delivery and targeting
-
Langer R. Drug delivery and targeting. Nature. 392:(6679 Suppl.):1998;5-10.
-
(1998)
Nature
, vol.392
, Issue.6679 SUPPL.
, pp. 5-10
-
-
Langer, R.1
-
5
-
-
0346551010
-
Polymer conjugates with anticancer activity
-
Putnam D., Kopeček J. Polymer conjugates with anticancer activity. Adv. Polym. Sci. 122:1995;55-123.
-
(1995)
Adv. Polym. Sci.
, vol.122
, pp. 55-123
-
-
Putnam, D.1
Kopeček, J.2
-
6
-
-
0041181628
-
HPMA copolymer-anticancer drug conjugates: Design, activity, and mechanism of action
-
Kopeček J., Kopečková P., Minko T., Lu Z.R. HPMA copolymer-anticancer drug conjugates: design, activity, and mechanism of action. Eur. J. Pharm. Biopharm. 50:(1):2000;61-81.
-
(2000)
Eur. J. Pharm. Biopharm.
, vol.50
, Issue.1
, pp. 61-81
-
-
Kopeček, J.1
Kopečková, P.2
Minko, T.3
Lu, Z.R.4
-
7
-
-
0023714439
-
Solute transport across the mammalian lysosome membrane
-
Foster S., Lloyd J.B. Solute transport across the mammalian lysosome membrane. Biochim. Biophys. Acta. 947:(3):1988;465-491.
-
(1988)
Biochim. Biophys. Acta
, vol.947
, Issue.3
, pp. 465-491
-
-
Foster, S.1
Lloyd, J.B.2
-
8
-
-
0000738920
-
Conjugation of methotrexate to poly(L-lysine) increases drug transport and overcomes drug resistance in cultured cells
-
Ryser H.J.-P., Shen W.-C. Conjugation of methotrexate to poly(L-lysine) increases drug transport and overcomes drug resistance in cultured cells. Proc. Natl. Acad. Sci. 75:(4):1978;3867-3870.
-
(1978)
Proc. Natl. Acad. Sci.
, vol.75
, Issue.4
, pp. 3867-3870
-
-
Ryser, H.J.-P.1
Shen, W.-C.2
-
9
-
-
0027816261
-
Bovine serum albumin-doxorubicin conjugate overcomes multidrug resistance in a rat hepatoma
-
Ohkawa K., Hatano T., Yamada K., Joh K., Takada K., Tsukada Y., Matsuda M. Bovine serum albumin-doxorubicin conjugate overcomes multidrug resistance in a rat hepatoma. Cancer Res. 53:(18):1993;4238-4242.
-
(1993)
Cancer Res.
, vol.53
, Issue.18
, pp. 4238-4242
-
-
Ohkawa, K.1
Hatano, T.2
Yamada, K.3
Joh, K.4
Takada, K.5
Tsukada, Y.6
Matsuda, M.7
-
10
-
-
0016260069
-
Lysosomotropic agents
-
de Duve C., de Barsy T., Poole B., Trouet A., Tulkens P., Van Hoof F. Lysosomotropic agents. Biochem. Pharmacol. 23:(18):1974;2495-2531.
-
(1974)
Biochem. Pharmacol.
, vol.23
, Issue.18
, pp. 2495-2531
-
-
De Duve, C.1
De Barsy, T.2
Poole, B.3
Trouet, A.4
Tulkens, P.5
Van Hoof, F.6
-
11
-
-
0003056238
-
Biodegradation of polymers for biomedical use
-
H. Benoit, & P. Rempp. Oxford: Pergamon Press
-
Kopeček J. Biodegradation of polymers for biomedical use. Benoit H., Rempp P. IUPAC Macromolecules. 1982;305-320 Pergamon Press, Oxford.
-
(1982)
IUPAC Macromolecules
, pp. 305-320
-
-
Kopeček, J.1
-
12
-
-
0021354472
-
Controlled biodegradability of polymers - A key to drug delivery systems
-
Kopeček J. Controlled biodegradability of polymers - a key to drug delivery systems. Biomaterials. 5:(1):1984;19-25.
-
(1984)
Biomaterials
, vol.5
, Issue.1
, pp. 19-25
-
-
Kopeček, J.1
-
13
-
-
85031234385
-
-
Synthetic polymeric drugs, US Pat. 5037883, August 6, 1991
-
J. Kopeček, P. Rejmanová, J. Strohalm, K. Ulbrich, B. Říhová, V. Chytrý, J.B. Lloyd, R. Duncan, Synthetic polymeric drugs, US Pat. 5037883, August 6, 1991.
-
-
-
Kopeček, J.1
Rejmanová, P.2
Strohalm, J.3
Ulbrich, K.4
Říhová, B.5
Chytrý, V.6
Lloyd, J.B.7
Duncan, R.8
-
14
-
-
0028346174
-
Bioadhesive N-(2-hydroxypropyl)methacrylamide copolymers for colon-specific drug delivery
-
Kopečková P., Rathi R.C., Takada S., Říhová B., Berenson M.M., Kopeček J. Bioadhesive N-(2-hydroxypropyl)methacrylamide copolymers for colon-specific drug delivery. J. Controlled Release. 28:1994;211-222.
-
(1994)
J. Controlled Release
, vol.28
, pp. 211-222
-
-
Kopečková, P.1
Rathi, R.C.2
Takada, S.3
Říhová, B.4
Berenson, M.M.5
Kopeček, J.6
-
15
-
-
0029084968
-
Site-specific drug delivery and penetration enhancement in the gastrointestinal tract
-
Yeh P.Y., Berenson M.M., Samowitz W.S., Kopečková P., Kopeček J. Site-specific drug delivery and penetration enhancement in the gastrointestinal tract. J. Controlled Release. 36:1995;109-124.
-
(1995)
J. Controlled Release
, vol.36
, pp. 109-124
-
-
Yeh, P.Y.1
Berenson, M.M.2
Samowitz, W.S.3
Kopečková, P.4
Kopeček, J.5
-
16
-
-
0032211994
-
Delivery of antisense oligonucleotides using HPMA polymer: Synthesis of a thiol polymer and its conjugation to water-soluble molecules
-
Wang L., Kristensen J., Ruffner D.E. Delivery of antisense oligonucleotides using HPMA polymer: synthesis of a thiol polymer and its conjugation to water-soluble molecules. Bioconjug. Chem. 9:(6):1998;749-757.
-
(1998)
Bioconjug. Chem.
, vol.9
, Issue.6
, pp. 749-757
-
-
Wang, L.1
Kristensen, J.2
Ruffner, D.E.3
-
17
-
-
0242585472
-
The cytoplasmic escape and nuclear accumulation of endocytosed and microinjected HPMA copolymers and a basic kinetic study in Hep G2 cells
-
Article 32
-
K.D. Jensen, P. Kopečková, J.H.B. Bridge, J. Kopeček, The cytoplasmic escape and nuclear accumulation of endocytosed and microinjected HPMA copolymers and a basic kinetic study in Hep G2 cells, AAPS PharmSci [serial online] 3(4) (2001) Article 32.
-
(2001)
AAPS PharmSci [serial online]
, vol.3
, Issue.4
-
-
Jensen, K.D.1
Kopečková, P.2
Bridge, J.H.B.3
Kopeček, J.4
-
18
-
-
0031593184
-
HPMA-based biodegradable hydrogels containing different forms of doxorubicin. Antitumor effects and biocompatibility
-
Říhová B., Šrogl J., Jelínková M., Hovorka O., Burešová M., Šubr V., Ulbrich K. HPMA-based biodegradable hydrogels containing different forms of doxorubicin. Antitumor effects and biocompatibility. Ann. NY Acad. Sci. 831:1997;57-71.
-
(1997)
Ann. NY Acad. Sci.
, vol.831
, pp. 57-71
-
-
Říhová, B.1
Šrogl, J.2
Jelínková, M.3
Hovorka, O.4
Burešová, M.5
Šubr, V.6
Ulbrich, K.7
-
19
-
-
84947149186
-
Release of macromolecules and daunomycin from hydrophilic gels containing enzymatically degradable bonds
-
Šubr V., Duncan R., Kopeček J. Release of macromolecules and daunomycin from hydrophilic gels containing enzymatically degradable bonds. J. Biomater. Sci. Polym. Ed. 1:(4):1990;261-278.
-
(1990)
J. Biomater. Sci. Polym. Ed.
, vol.1
, Issue.4
, pp. 261-278
-
-
Šubr, V.1
Duncan, R.2
Kopeček, J.3
-
20
-
-
0033521939
-
Hybrid hydrogels assembled from synthetic polymers and coiled-coil protein domains
-
Wang C., Stewart R.J., Kopeček J. Hybrid hydrogels assembled from synthetic polymers and coiled-coil protein domains. Nature. 397:(6718):1999;417-420.
-
(1999)
Nature
, vol.397
, Issue.6718
, pp. 417-420
-
-
Wang, C.1
Stewart, R.J.2
Kopeček, J.3
-
21
-
-
0034117688
-
Self-assembled peptides exposing epitopes recognizable by human lymphoma cells
-
Tang A., Wang C., Stewart R., Kopeček J. Self-assembled peptides exposing epitopes recognizable by human lymphoma cells. Bioconjug. Chem. 11:(3):2000;363-371.
-
(2000)
Bioconjug. Chem.
, vol.11
, Issue.3
, pp. 363-371
-
-
Tang, A.1
Wang, C.2
Stewart, R.3
Kopeček, J.4
-
22
-
-
0036258053
-
Presentation of epitopes on genetically engineered peptides and selection of lymphoma-targeting moieties based on epitope biorecognition
-
Tang A., Kopeček J. Presentation of epitopes on genetically engineered peptides and selection of lymphoma-targeting moieties based on epitope biorecognition. Biomacromolecules. 3:(3):2002;421-431.
-
(2002)
Biomacromolecules
, vol.3
, Issue.3
, pp. 421-431
-
-
Tang, A.1
Kopeček, J.2
-
23
-
-
0021271357
-
Tyrosinamide residues enhance pinocytic capture of N-(2-hydroxypropyl)methacrylamide copolymers
-
Duncan R., Cable H.C., Rejmanová P., Kopeček J., Lloyd J.B. Tyrosinamide residues enhance pinocytic capture of N-(2-hydroxypropyl)methacrylamide copolymers. Biochim. Biophys. Acta. 799:(1):1984;1-8.
-
(1984)
Biochim. Biophys. Acta
, vol.799
, Issue.1
, pp. 1-8
-
-
Duncan, R.1
Cable, H.C.2
Rejmanová, P.3
Kopeček, J.4
Lloyd, J.B.5
-
24
-
-
0022982552
-
Interaction of a cationic N-(2-hydroxypropyl)methacrylamide copolymer with rat visceral yolk sac cultured in vitro and rat liver in vivo
-
McCormick L.A., Seymour L.C.W., Duncan R., Kopeček J. Interaction of a cationic N-(2-hydroxypropyl)methacrylamide copolymer with rat visceral yolk sac cultured in vitro and rat liver in vivo. J. Bioact. Comp. Polym. 1:1986;4-19.
-
(1986)
J. Bioact. Comp. Polym.
, vol.1
, pp. 4-19
-
-
McCormick, L.A.1
Seymour, L.C.W.2
Duncan, R.3
Kopeček, J.4
-
25
-
-
0000385527
-
Enzymatic cleavage of side-chains of synthetic water-soluble polymers
-
Drobník J., Kopeček J., Labský J., Rejmanová P., Exner J., Saudek V., Kálal J. Enzymatic cleavage of side-chains of synthetic water-soluble polymers. Makromol. Chem. 177:1976;2833-2848.
-
(1976)
Makromol. Chem.
, vol.177
, pp. 2833-2848
-
-
Drobník, J.1
Kopeček, J.2
Labský, J.3
Rejmanová, P.4
Exner, J.5
Saudek, V.6
Kálal, J.7
-
26
-
-
0026584015
-
Polymers containing enzymatically degradable bonds. XII. Effect of spacer structure on the rate of release of daunomycin and adriamycin from poly[N-(2-hydroxypropyl)methacrylamide] copolymer drug carriers in vitro and antitumour activity measured in vivo
-
Šubr V., Strohalm J., Ulbrich K., Duncan R., Hume I.C. Polymers containing enzymatically degradable bonds. XII. Effect of spacer structure on the rate of release of daunomycin and adriamycin from poly[N-(2-hydroxypropyl)methacrylamide] copolymer drug carriers in vitro and antitumour activity measured in vivo. J. Controlled Release. 18:1992;123-132.
-
(1992)
J. Controlled Release
, vol.18
, pp. 123-132
-
-
Šubr, V.1
Strohalm, J.2
Ulbrich, K.3
Duncan, R.4
Hume, I.C.5
-
27
-
-
0344129078
-
Synthesis of HPMA copolymer containing adrimaycin bound via an acid-labile spacer and its activity toward human ovarian carcinoma cells
-
Choi W.-M., Kopečková P., Minko T., Kopeček J. Synthesis of HPMA copolymer containing adrimaycin bound via an acid-labile spacer and its activity toward human ovarian carcinoma cells. J. Bioactive Compat. Polym. 14:1999;447-556.
-
(1999)
J. Bioactive Compat. Polym.
, vol.14
, pp. 447-556
-
-
Choi, W.-M.1
Kopečková, P.2
Minko, T.3
Kopeček, J.4
-
28
-
-
0000859980
-
Polymers containing enzymatically degradable bonds. 8. Degradation of oligopeptide sequences in N-(2-hydroxypropyl)methacrylamide copolymers by bovine spleen cathepsin B
-
Rejmanová P., Pohl J., Baudyš M., Kostka V., Kopeček J. Polymers containing enzymatically degradable bonds. 8. Degradation of oligopeptide sequences in N-(2-hydroxypropyl)methacrylamide copolymers by bovine spleen cathepsin B. Makromol. Chem. 184:1983;2009-2020.
-
(1983)
Makromol. Chem.
, vol.184
, pp. 2009-2020
-
-
Rejmanová, P.1
Pohl, J.2
Baudyš, M.3
Kostka, V.4
Kopeček, J.5
-
29
-
-
0022002504
-
Stability in rat plasma and serum of lysosomally degradable oligopeptide sequences in N-(2-hydroxypropyl)methacrylamide copolymers
-
Rejmanová P., Kopeček J., Duncan R., Lloyd J.B. Stability in rat plasma and serum of lysosomally degradable oligopeptide sequences in N-(2-hydroxypropyl)methacrylamide copolymers. Biomaterials. 6:(1):1985;45-48.
-
(1985)
Biomaterials
, vol.6
, Issue.1
, pp. 45-48
-
-
Rejmanová, P.1
Kopeček, J.2
Duncan, R.3
Lloyd, J.B.4
-
30
-
-
0020467066
-
Degradation of side-chains of N-(2-hydroxypropyl)methacrylamide copolymers by lysosomal thiol-proteinases
-
Duncan R., Cable H.C., Lloyd J.B., Rejmanová P., Kopeček J. Degradation of side-chains of N-(2-hydroxypropyl)methacrylamide copolymers by lysosomal thiol-proteinases. Biosci. Rep. 2:(12):1982;1041-1046.
-
(1982)
Biosci. Rep.
, vol.2
, Issue.12
, pp. 1041-1046
-
-
Duncan, R.1
Cable, H.C.2
Lloyd, J.B.3
Rejmanová, P.4
Kopeček, J.5
-
31
-
-
0000859981
-
Polymers containing enzymatically degradable bonds. 7. Design of oligopeptide side-chains in poly[N-(2-hydroxypropyl)methacrylamide] copolymers to promote efficient degradation by lysosomal enzymes
-
Duncan R., Cable H.C., Lloyd J.B., Rejmanová P., Kopeček J. Polymers containing enzymatically degradable bonds. 7. Design of oligopeptide side-chains in poly[N-(2-hydroxypropyl)methacrylamide] copolymers to promote efficient degradation by lysosomal enzymes. Makromol. Chem. 184:1983;1997-2008.
-
(1983)
Makromol. Chem.
, vol.184
, pp. 1997-2008
-
-
Duncan, R.1
Cable, H.C.2
Lloyd, J.B.3
Rejmanová, P.4
Kopeček, J.5
-
32
-
-
0020523633
-
Immunogenicity of N-(2-hydroxypropyl)-methacrylamide copolymers - Potential hapten or drug carriers
-
Říhová B., Ulbrich K., Kopeček J., Mančal P. Immunogenicity of N-(2-hydroxypropyl)-methacrylamide copolymers - potential hapten or drug carriers. Folia Microbiol. 28:(3):1983;217-227.
-
(1983)
Folia Microbiol.
, vol.28
, Issue.3
, pp. 217-227
-
-
Říhová, B.1
Ulbrich, K.2
Kopeček, J.3
Mančal, P.4
-
33
-
-
0021274948
-
Effect of the chemical structure of N-(2-hydroxypropyl)methacrylamide copolymers on their ability to induce antibody formation in inbred strains of mice
-
Říhová B., Kopeček J., Ulbrich K., Pospíšil M., Mančal P. Effect of the chemical structure of N-(2-hydroxypropyl)methacrylamide copolymers on their ability to induce antibody formation in inbred strains of mice. Biomaterials. 5:(3):1984;143-148.
-
(1984)
Biomaterials
, vol.5
, Issue.3
, pp. 143-148
-
-
Říhová, B.1
Kopeček, J.2
Ulbrich, K.3
Pospíšil, M.4
Mančal, P.5
-
35
-
-
0022952658
-
Activity of complement in the presence of N-(2-hydroxypropyl)methacrylamide copolymers
-
Šimečková J., Plocová D., Říhová B., Kopeček J. Activity of complement in the presence of N-(2-hydroxypropyl)methacrylamide copolymers. J. Bioact. Comp. Polym. 1:1986;20-31.
-
(1986)
J. Bioact. Comp. Polym.
, vol.1
, pp. 20-31
-
-
Šimečková, J.1
Plocová, D.2
Říhová, B.3
Kopeček, J.4
-
36
-
-
0022379009
-
Biological properties of targetable poly[N-(2-hydroxypropyl)methacrylamide]-antibody conjugates
-
Říhová B., Kopeček J. Biological properties of targetable poly[N-(2-hydroxypropyl)methacrylamide]-antibody conjugates. J. Controlled Release. 2:1985;289-310.
-
(1985)
J. Controlled Release
, vol.2
, pp. 289-310
-
-
Říhová, B.1
Kopeček, J.2
-
37
-
-
0025283251
-
Immunogenicity of protein-N-(2-hydroxypropyl)methacrylamide copolymer conjugates measured in A/J and B10 mice
-
Flanagan P.A., Duncan R., Říhová B., Šubr V., Kopeček J. Immunogenicity of protein-N-(2-hydroxypropyl)methacrylamide copolymer conjugates measured in A/J and B10 mice. J. Bioact. Comp. Polym. 5:1990;151-166.
-
(1990)
J. Bioact. Comp. Polym.
, vol.5
, pp. 151-166
-
-
Flanagan, P.A.1
Duncan, R.2
Říhová, B.3
Šubr, V.4
Kopeček, J.5
-
38
-
-
0032959549
-
Phase I clinical and pharmacokinetic study of PK1 [N-(2-hydroxypropyl)methacrylamide copolymer doxorubicin]: First member of a new class of chemotherapeutic agents-drug-polymer conjugates
-
Vasey P.A., Kaye S.B., Morrison R., Twelves C., Wilson P., Duncan R., Thomson A.H., Murray L.S., Hilditch T.E., Murray T., Burtles S., Fraier D., Frigerio E., Cassidy J. Phase I clinical and pharmacokinetic study of PK1 [N-(2-hydroxypropyl)methacrylamide copolymer doxorubicin]: first member of a new class of chemotherapeutic agents-drug-polymer conjugates. Clin. Cancer Res. 5:(1):1999;83-94.
-
(1999)
Clin. Cancer Res.
, vol.5
, Issue.1
, pp. 83-94
-
-
Vasey, P.A.1
Kaye, S.B.2
Morrison, R.3
Twelves, C.4
Wilson, P.5
Duncan, R.6
Thomson, A.H.7
Murray, L.S.8
Hilditch, T.E.9
Murray, T.10
Burtles, S.11
Fraier, D.12
Frigerio, E.13
Cassidy, J.14
-
39
-
-
0023102353
-
Soluble crosslinked N-(2-hydroxypropyl)methacrylamide copolymers as potential drug carriers. 2. Effect of molecular weight on blood clearance and body distribution in the rat after intravenous administration. Distribution of unfractionated copolymer after intraperitoneal, subcutaneous or oral administration
-
Cartlidge S.A., Duncan R., Lloyd J.B., Kopečková-Rejmanová P., Kopeček J. Soluble crosslinked N-(2-hydroxypropyl)methacrylamide copolymers as potential drug carriers. 2. Effect of molecular weight on blood clearance and body distribution in the rat after intravenous administration. Distribution of unfractionated copolymer after intraperitoneal, subcutaneous or oral administration. J. Controlled Release. 4:1987;253-264.
-
(1987)
J. Controlled Release
, vol.4
, pp. 253-264
-
-
Cartlidge, S.A.1
Duncan, R.2
Lloyd, J.B.3
Kopečková-Rejmanová, P.4
Kopeček, J.5
-
40
-
-
0017089608
-
New types of synthetic infusion solutions. III. Elimination and retention of poly-[N-(2-hydroxypropyl)methacrylamide] in a test organism
-
Šprincl L., Exner J., Štěrba O., Kopeček J. New types of synthetic infusion solutions. III. Elimination and retention of poly-[N-(2-hydroxypropyl)methacrylamide] in a test organism. J. Biomed. Mater. Res. 10:(6):1976;953-963.
-
(1976)
J. Biomed. Mater. Res.
, vol.10
, Issue.6
, pp. 953-963
-
-
Šprincl, L.1
Exner, J.2
Štěrba, O.3
Kopeček, J.4
-
41
-
-
0023450012
-
w) of N-(2-hydroxypropyl)methacrylamide copolymers on body distribution and rate of excretion after subcutaneous, intraperitoneal, and intravenous administration to rats
-
w) of N-(2-hydroxypropyl)methacrylamide copolymers on body distribution and rate of excretion after subcutaneous, intraperitoneal, and intravenous administration to rats. J. Biomed. Mater. Res. 21:(11):1987;1341-1358.
-
(1987)
J. Biomed. Mater. Res.
, vol.21
, Issue.11
, pp. 1341-1358
-
-
Seymour, L.W.1
Duncan, R.2
Strohalm, J.3
Kopeček, J.4
-
42
-
-
0041461026
-
High-molecular weight HPMA copolymer-adriamycin conjugates
-
Dvořák M., Kopečková P., Kopeček J. High-molecular weight HPMA copolymer-adriamycin conjugates. J. Controlled Release. 60:(2-3):1999;321-332.
-
(1999)
J. Controlled Release
, vol.60
, Issue.2-3
, pp. 321-332
-
-
Dvořák, M.1
Kopečková, P.2
Kopeček, J.3
-
43
-
-
0034046024
-
The influence of cytotoxicity of macromolecules and of VEGF gene modulated vascular permeability on the enhanced permeability and retention effect in resistant solid tumors
-
Minko T., Kopečková P., Pozharov V., Jensen K.D., Kopeček J. The influence of cytotoxicity of macromolecules and of VEGF gene modulated vascular permeability on the enhanced permeability and retention effect in resistant solid tumors. Pharm. Res. 17:(5):2000;505-514.
-
(2000)
Pharm. Res.
, vol.17
, Issue.5
, pp. 505-514
-
-
Minko, T.1
Kopečková, P.2
Pozharov, V.3
Jensen, K.D.4
Kopeček, J.5
-
44
-
-
0016322758
-
The role of surface carbohydrates in the hepatic recognition and transport of circulating glycoproteins
-
Ashwell G., Morell A.G. The role of surface carbohydrates in the hepatic recognition and transport of circulating glycoproteins. Adv. Enzymol. Relat. Areas Mol. Biol. 41:1974;99-128.
-
(1974)
Adv. Enzymol. Relat. Areas Mol. Biol.
, vol.41
, pp. 99-128
-
-
Ashwell, G.1
Morell, A.G.2
-
45
-
-
0021192483
-
The hepatic asialoglycoprotein receptor
-
Schwartz A.L. The hepatic asialoglycoprotein receptor. CRC Crit. Rev. Biochem. 16:(3):1984;207-233.
-
(1984)
CRC Crit. Rev. Biochem.
, vol.16
, Issue.3
, pp. 207-233
-
-
Schwartz, A.L.1
-
46
-
-
0020682412
-
Targeting of N-(2-hydroxypropyl)methacrylamide copolymers to liver by incorporation of galactose residues
-
Duncan R., Kopeček J., Rejmanová P., Lloyd J.B. Targeting of N-(2-hydroxypropyl)methacrylamide copolymers to liver by incorporation of galactose residues. Biochim. Biophys. Acta. 755:(3):1983;518-521.
-
(1983)
Biochim. Biophys. Acta
, vol.755
, Issue.3
, pp. 518-521
-
-
Duncan, R.1
Kopeček, J.2
Rejmanová, P.3
Lloyd, J.B.4
-
47
-
-
0022635574
-
Fate of N-(2-hydroxypropyl)methacrylamide copolymers with pendant galactosamine residues after intravenous administration to rats
-
Duncan R., Seymour L.C., Scarlett L., Lloyd J.B., Rejmanová P., Kopeček J. Fate of N-(2-hydroxypropyl)methacrylamide copolymers with pendant galactosamine residues after intravenous administration to rats. Biochim. Biophys. Acta. 880:(1):1986;62-71.
-
(1986)
Biochim. Biophys. Acta
, vol.880
, Issue.1
, pp. 62-71
-
-
Duncan, R.1
Seymour, L.C.2
Scarlett, L.3
Lloyd, J.B.4
Rejmanová, P.5
Kopeček, J.6
-
48
-
-
0012630444
-
Methods of targeting N-(2-hydroxypropyl)methacrylamide copolymers to particular cell types
-
Duncan R., Lloyd J.B., Rejmanová P., Kopeček J. Methods of targeting N-(2-hydroxypropyl)methacrylamide copolymers to particular cell types. Makromol. Chem. Suppl. 9:1985;3-12.
-
(1985)
Makromol. Chem. Suppl.
, vol.9
, pp. 3-12
-
-
Duncan, R.1
Lloyd, J.B.2
Rejmanová, P.3
Kopeček, J.4
-
49
-
-
0023129812
-
Soluble crosslinked N-2-hydroxypropyl)methacrylamide copolymers as potential drug carriers. 3. Targeting by incorporation of galactosamine residues. Effect of route of administration
-
Cartlidge S.A., Duncan R., Lloyd J.B., Kopečková-Rejmanová P., Kopeček J. Soluble crosslinked N-2-hydroxypropyl)methacrylamide copolymers as potential drug carriers. 3. Targeting by incorporation of galactosamine residues. Effect of route of administration. J. Controlled Release. 4:1987;265-278.
-
(1987)
J. Controlled Release
, vol.4
, pp. 265-278
-
-
Cartlidge, S.A.1
Duncan, R.2
Lloyd, J.B.3
Kopečková-Rejmanová, P.4
Kopeček, J.5
-
50
-
-
0024469053
-
Anticancer agents coupled to N-(2-hydroxypropyl)methacylamide copolymers. 3. Evaluation of adriamycin conjugates against mouse leukaemia L1210 in vivo
-
Duncan R., Hume I.C., Kopečková P., Ulbrich K., Strohalm J., Kopeček J. Anticancer agents coupled to N-(2-hydroxypropyl)methacylamide copolymers. 3. Evaluation of adriamycin conjugates against mouse leukaemia L1210 in vivo. J. Controlled Release. 10:1989;51-63.
-
(1989)
J. Controlled Release
, vol.10
, pp. 51-63
-
-
Duncan, R.1
Hume, I.C.2
Kopečková, P.3
Ulbrich, K.4
Strohalm, J.5
Kopeček, J.6
-
51
-
-
0025855856
-
Comparison of the liver subcellular distribution of free daunomycin and that bound to galactosamine targeted N-(2-hydroxypropyl)methacrylamide copolymers, following intravenous administration in the rat
-
Wedge S.R., Duncan R., Kopečková P. Comparison of the liver subcellular distribution of free daunomycin and that bound to galactosamine targeted N-(2-hydroxypropyl)methacrylamide copolymers, following intravenous administration in the rat. Br. J. Cancer. 63:(4):1991;546-549.
-
(1991)
Br. J. Cancer
, vol.63
, Issue.4
, pp. 546-549
-
-
Wedge, S.R.1
Duncan, R.2
Kopečková, P.3
-
52
-
-
0033013012
-
Preliminary clinical study of the distribution of HPMA copolymers bearing doxorubicin and galactosamine
-
Julyan P.J., Seymour L.W., Ferry D.R., Daryani S., Boivin C.M., Doran J., David M., Anderson D., Christodoulou C., Young A.M., Hesslewood S., Kerr D.J. Preliminary clinical study of the distribution of HPMA copolymers bearing doxorubicin and galactosamine. J. Controlled Release. 57:(3):1999;281-290.
-
(1999)
J. Controlled Release
, vol.57
, Issue.3
, pp. 281-290
-
-
Julyan, P.J.1
Seymour, L.W.2
Ferry, D.R.3
Daryani, S.4
Boivin, C.M.5
Doran, J.6
David, M.7
Anderson, D.8
Christodoulou, C.9
Young, A.M.10
Hesslewood, S.11
Kerr, D.J.12
-
53
-
-
0037087719
-
Hepatic drug targeting: Phase I evaluation of polymer-bound doxorubicin
-
Seymour L.W., Ferry D.R., Anderson D., Hesslewood S., Julyan P.J., Poyner R., Doran J., Young A.M., Burtles S., Kerr D.J. Hepatic drug targeting: phase I evaluation of polymer-bound doxorubicin. J. Clin. Oncol. 20:(6):2002;1668-1676.
-
(2002)
J. Clin. Oncol.
, vol.20
, Issue.6
, pp. 1668-1676
-
-
Seymour, L.W.1
Ferry, D.R.2
Anderson, D.3
Hesslewood, S.4
Julyan, P.J.5
Poyner, R.6
Doran, J.7
Young, A.M.8
Burtles, S.9
Kerr, D.J.10
-
54
-
-
0019884074
-
Pinocytic uptake and intracellular degradation of N-(2-hydroxypropyl)methacrylamide copolymers. A potential drug delivery system
-
Duncan R., Rejmanová P., Kopeček J., Lloyd J.B. Pinocytic uptake and intracellular degradation of N-(2-hydroxypropyl)methacrylamide copolymers. A potential drug delivery system. Biochim. Biophys. Acta. 678:(1):1981;143-150.
-
(1981)
Biochim. Biophys. Acta
, vol.678
, Issue.1
, pp. 143-150
-
-
Duncan, R.1
Rejmanová, P.2
Kopeček, J.3
Lloyd, J.B.4
-
55
-
-
0032580444
-
Targetable HPMA copolymer-adriamycin conjugates. Recognition, internalization, and subcellular fate
-
Omelyanenko V., Kopečková P., Gentry C., Kopeček J. Targetable HPMA copolymer-adriamycin conjugates. Recognition, internalization, and subcellular fate. J. Controlled Release. 53:(1-3):1998;25-37.
-
(1998)
J. Controlled Release
, vol.53
, Issue.1-3
, pp. 25-37
-
-
Omelyanenko, V.1
Kopečková, P.2
Gentry, C.3
Kopeček, J.4
-
56
-
-
0032498552
-
HPMA copolymer-anticancer drug-OV-TL16 antibody conjugates. II. Processing in epithelial ovarian carcinoma cells in vitro
-
Omelyanenko V., Gentry C., Kopečková P., Kopeček J. HPMA copolymer-anticancer drug-OV-TL16 antibody conjugates. II. Processing in epithelial ovarian carcinoma cells in vitro. Int. J. Cancer. 75:(4):1998;600-608.
-
(1998)
Int. J. Cancer
, vol.75
, Issue.4
, pp. 600-608
-
-
Omelyanenko, V.1
Gentry, C.2
Kopečková, P.3
Kopeček, J.4
-
57
-
-
0001451912
-
Cytoplasmic delivery and nuclear targeting of HPMA copolymer-tat conjugates to human ovarian carcinoma cells
-
Nori A., Jensen K.D., Kopečková P., Kopeček J. Cytoplasmic delivery and nuclear targeting of HPMA copolymer-tat conjugates to human ovarian carcinoma cells. 28th International Symposium on Controlled Release of Bioactive Materials (San Diego, CA) :2001;854-855.
-
(2001)
28th International Symposium on Controlled Release of Bioactive Materials (San Diego, CA)
, pp. 854-855
-
-
Nori, A.1
Jensen, K.D.2
Kopečková, P.3
Kopeček, J.4
-
58
-
-
0033379680
-
Fomivirsen - A phosphorothioate oligonucleotide for the treatment of CMV retinitis
-
de Smet M.D., Meenken C.J., van den Horn G.J. Fomivirsen - a phosphorothioate oligonucleotide for the treatment of CMV retinitis. Ocul. Immunol. Inflamm. 7:(3-4):1999;189-198.
-
(1999)
Ocul. Immunol. Inflamm.
, vol.7
, Issue.3-4
, pp. 189-198
-
-
De Smet, M.D.1
Meenken, C.J.2
Van den Horn, G.J.3
-
59
-
-
0035845318
-
Antisense therapy in oncology: New hope for an old idea?
-
Tamm I., Dorken B., Hartmann G. Antisense therapy in oncology: new hope for an old idea? Lancet. 358:(9280):2001;489-497.
-
(2001)
Lancet
, vol.358
, Issue.9280
, pp. 489-497
-
-
Tamm, I.1
Dorken, B.2
Hartmann, G.3
-
60
-
-
0032522132
-
Phosphorothioate oligodeoxyribonucleotides dissociate from cationic lipids before entering the nucleus
-
Marcusson E.G., Bhat B., Manoharan M., Bennett C.F., Dean N.M. Phosphorothioate oligodeoxyribonucleotides dissociate from cationic lipids before entering the nucleus. Nucleic Acids Res. 26:(8):1998;2016-2023.
-
(1998)
Nucleic Acids Res.
, vol.26
, Issue.8
, pp. 2016-2023
-
-
Marcusson, E.G.1
Bhat, B.2
Manoharan, M.3
Bennett, C.F.4
Dean, N.M.5
-
61
-
-
0036179935
-
Intracellular processing of poly(ethyleneimine)/ribozyme complexes can be observed in living cells by using confocal laser scanning microscopy and inhibitor experiments
-
Merdan T., Kunath K., Fischer D., Kopeček J., Kissel T. Intracellular processing of poly(ethyleneimine)/ribozyme complexes can be observed in living cells by using confocal laser scanning microscopy and inhibitor experiments. Pharm. Res. 19:(2):2002;140-146.
-
(2002)
Pharm. Res.
, vol.19
, Issue.2
, pp. 140-146
-
-
Merdan, T.1
Kunath, K.2
Fischer, D.3
Kopeček, J.4
Kissel, T.5
-
62
-
-
0036738632
-
Antisense oligonucleotides delivered to the lysosome escape and actively inhibit the hepatitis B virus
-
Jensen K.D., Kopečková P., Kopeček J. Antisense oligonucleotides delivered to the lysosome escape and actively inhibit the hepatitis B virus. Bioconjug. Chem. 13:(5):2002;975-984.
-
(2002)
Bioconjug. Chem.
, vol.13
, Issue.5
, pp. 975-984
-
-
Jensen, K.D.1
Kopečková, P.2
Kopeček, J.3
-
63
-
-
0002723926
-
Basic principles of antisense therapeutics
-
S.T. Crooke. Berlin: Springer
-
Crooke S.T. Basic principles of antisense therapeutics. Crooke S.T. Antisense Research and Application. 1998;1-50 Springer, Berlin.
-
(1998)
Antisense Research and Application
, pp. 1-50
-
-
Crooke, S.T.1
-
64
-
-
0031821074
-
In vivo distribution and metabolism of a phosphorothioate oligonucleotide within rat liver after intravenous administration
-
Graham M.J., Crooke S.T., Monteith D.K., Cooper S.R., Lemonidis K.M., Stecker K.K., Martin M.J., Crooke R.M. In vivo distribution and metabolism of a phosphorothioate oligonucleotide within rat liver after intravenous administration. J. Pharmacol. Exp. Ther. 286:(1):1998;447-458.
-
(1998)
J. Pharmacol. Exp. Ther.
, vol.286
, Issue.1
, pp. 447-458
-
-
Graham, M.J.1
Crooke, S.T.2
Monteith, D.K.3
Cooper, S.R.4
Lemonidis, K.M.5
Stecker, K.K.6
Martin, M.J.7
Crooke, R.M.8
-
65
-
-
0035427644
-
Hepatic distribution of a phosphorothioate oligodeoxynucleotide within rodents following intravenous administration
-
Graham M.J., Crooke S.T., Lemonidis K.M., Gaus H.J., Templin M.V., Crooke R.M. Hepatic distribution of a phosphorothioate oligodeoxynucleotide within rodents following intravenous administration. Biochem. Pharmacol. 62:(3):2001;297-306.
-
(2001)
Biochem. Pharmacol.
, vol.62
, Issue.3
, pp. 297-306
-
-
Graham, M.J.1
Crooke, S.T.2
Lemonidis, K.M.3
Gaus, H.J.4
Templin, M.V.5
Crooke, R.M.6
-
66
-
-
0025613174
-
Rapid nuclear accumulation of injected oligodeoxyribonucleotides
-
Chin D.J., Green G.A., Zon G., Szoka F.C. Jr., Straubinger R.M. Rapid nuclear accumulation of injected oligodeoxyribonucleotides. New Biol. 2:(12):1990;1091-1100.
-
(1990)
New Biol.
, vol.2
, Issue.12
, pp. 1091-1100
-
-
Chin, D.J.1
Green, G.A.2
Zon, G.3
Szoka F.C., Jr.4
Straubinger, R.M.5
-
67
-
-
0031667333
-
Phosphorothioate antisense oligonucleotides induce the formation of nuclear bodies
-
Lorenz P., Baker B.F., Bennett C.F., Spector D.L. Phosphorothioate antisense oligonucleotides induce the formation of nuclear bodies. Mol. Biol. Cell. 9:(5):1998;1007-1023.
-
(1998)
Mol. Biol. Cell.
, vol.9
, Issue.5
, pp. 1007-1023
-
-
Lorenz, P.1
Baker, B.F.2
Bennett, C.F.3
Spector, D.L.4
-
68
-
-
0027181381
-
Intracellular disposition and metabolism of fluorescently-labeled unmodified and modified oligonucleotides microinjected into mammalian cells
-
Fisher T.L., Terhorst T., Cao X., Wagner R.W. Intracellular disposition and metabolism of fluorescently-labeled unmodified and modified oligonucleotides microinjected into mammalian cells. Nucleic Acids Res. 21:(16):1993;3857-3865.
-
(1993)
Nucleic Acids Res.
, vol.21
, Issue.16
, pp. 3857-3865
-
-
Fisher, T.L.1
Terhorst, T.2
Cao, X.3
Wagner, R.W.4
-
69
-
-
0027246678
-
Antisense gene inhibition by oligonucleotides containing C-5 propyne pyrimidines
-
Wagner R.W., Matteucci M.D., Lewis J.G., Gutierrez A.J., Moulds C., Froehler B.C. Antisense gene inhibition by oligonucleotides containing C-5 propyne pyrimidines. Science. 260:(5113):1993;1510-1513.
-
(1993)
Science
, vol.260
, Issue.5113
, pp. 1510-1513
-
-
Wagner, R.W.1
Matteucci, M.D.2
Lewis, J.G.3
Gutierrez, A.J.4
Moulds, C.5
Froehler, B.C.6
-
73
-
-
0035847008
-
Dissection of a nuclear localization signal
-
Hodel M.R., Corbett A.H., Hodel A.E. Dissection of a nuclear localization signal. J. Biol. Chem. 276:(2):2001;1317-1325.
-
(2001)
J. Biol. Chem.
, vol.276
, Issue.2
, pp. 1317-1325
-
-
Hodel, M.R.1
Corbett, A.H.2
Hodel, A.E.3
-
74
-
-
0018121958
-
Pinocytosis in the rat visceral yolk sac. Effects of temperature, metabolic inhibitors and some other modifiers
-
Duncan R., Lloyd J.B. Pinocytosis in the rat visceral yolk sac. Effects of temperature, metabolic inhibitors and some other modifiers. Biochim. Biophys. Acta. 544:(3):1978;647-655.
-
(1978)
Biochim. Biophys. Acta
, vol.544
, Issue.3
, pp. 647-655
-
-
Duncan, R.1
Lloyd, J.B.2
-
75
-
-
0024454465
-
Fusion accessibility of endocytic compartments along the recycling and lysosomal endocytic pathways in intact cells
-
Salzman N.H., Maxfield F.R. Fusion accessibility of endocytic compartments along the recycling and lysosomal endocytic pathways in intact cells. J. Cell. Biol. 109:(5):1989;2097-2104.
-
(1989)
J. Cell. Biol.
, vol.109
, Issue.5
, pp. 2097-2104
-
-
Salzman, N.H.1
Maxfield, F.R.2
-
76
-
-
0002034191
-
Cell-penetrating peptides
-
Lindgren M., Hallbrink M., Prochiantz A., Langel U. Cell-penetrating peptides. Trends Pharmacol. Sci. 21:(3):2000;99-103.
-
(2000)
Trends Pharmacol. Sci.
, vol.21
, Issue.3
, pp. 99-103
-
-
Lindgren, M.1
Hallbrink, M.2
Prochiantz, A.3
Langel, U.4
-
77
-
-
0034237577
-
Protein transduction: Unrestricted delivery into all cells?
-
Schwarze S.R., Hruska K.A., Dowdy S.F. Protein transduction: unrestricted delivery into all cells? Trends Cell. Biol. 10:(7):2000;290-295.
-
(2000)
Trends Cell. Biol.
, vol.10
, Issue.7
, pp. 290-295
-
-
Schwarze, S.R.1
Hruska, K.A.2
Dowdy, S.F.3
-
78
-
-
0031759170
-
Transduction of full-length Tat fusion proteins into mammalian cells: Tat-p27kip1 induces cell migration
-
Nagahara H., Vocero-Akbani A.M., Snyder E.L., Ho A., Latham D.G., Lissy N.A., Becker-Hapak M., Ezhevsky S.A., Dowdy S.F. Transduction of full-length Tat fusion proteins into mammalian cells: Tat-p27kip1 induces cell migration. Nat. Med. 4:(12):1998;1449-1452.
-
(1998)
Nat. Med.
, vol.4
, Issue.12
, pp. 1449-1452
-
-
Nagahara, H.1
Vocero-Akbani, A.M.2
Snyder, E.L.3
Ho, A.4
Latham, D.G.5
Lissy, N.A.6
Becker-Hapak, M.7
Ezhevsky, S.A.8
Dowdy, S.F.9
-
79
-
-
0033520487
-
In vivo protein transduction: Delivery of a biologically active protein into the mouse
-
Schwarze S.R., Ho A., Vocero-Akbani A., Dowdy S.F. In vivo protein transduction: delivery of a biologically active protein into the mouse. Science. 285:(5433):1999;1569-1572.
-
(1999)
Science
, vol.285
, Issue.5433
, pp. 1569-1572
-
-
Schwarze, S.R.1
Ho, A.2
Vocero-Akbani, A.3
Dowdy, S.F.4
-
80
-
-
0034006169
-
Tat peptide-derivatized magnetic nanoparticles allow in vivo tracking and recovery of progenitor cells
-
Lewin M., Carlesso N., Tung C.H., Tang X.W., Cory D., Scadden D.T., Weissleder R. Tat peptide-derivatized magnetic nanoparticles allow in vivo tracking and recovery of progenitor cells. Nat. Biotechnol. 18:(4):2000;410-414.
-
(2000)
Nat. Biotechnol.
, vol.18
, Issue.4
, pp. 410-414
-
-
Lewin, M.1
Carlesso, N.2
Tung, C.H.3
Tang, X.W.4
Cory, D.5
Scadden, D.T.6
Weissleder, R.7
-
81
-
-
0035902477
-
Tat peptide on the surface of liposomes affords their efficient intracellular delivery even at low temperature and in the presence of metabolic inhibitors
-
Torchilin V.P., Rammohan R., Weissig V., Levchenko T.S. Tat peptide on the surface of liposomes affords their efficient intracellular delivery even at low temperature and in the presence of metabolic inhibitors. Proc. Natl. Acad. Sci. USA. 98:(15):2001;8786-8791.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, Issue.15
, pp. 8786-8791
-
-
Torchilin, V.P.1
Rammohan, R.2
Weissig, V.3
Levchenko, T.S.4
-
82
-
-
0034141430
-
In vivo protein transduction: Intracellular delivery of biologically active proteins, compounds and DNA
-
Schwarze S.R., Dowdy S.F. In vivo protein transduction: Intracellular delivery of biologically active proteins, compounds and DNA. Trends Pharmacol. Sci. 21:(2):2000;45-48.
-
(2000)
Trends Pharmacol. Sci.
, vol.21
, Issue.2
, pp. 45-48
-
-
Schwarze, S.R.1
Dowdy, S.F.2
-
83
-
-
0037255080
-
Tat conjugated synthetic macromolecules facilitate cytoplasmic drug delivery to human ovarian carcinoma cells
-
in press
-
A. Nori, K.D. Jensen, M. Tijerina, P. Kopečková, J. Kopeček, Tat conjugated synthetic macromolecules facilitate cytoplasmic drug delivery to human ovarian carcinoma cells, Bioconjug. Chem. (2003) in press.
-
(2003)
Bioconjug. Chem.
-
-
Nori, A.1
Jensen, K.D.2
Tijerina, M.3
Kopečková, P.4
Kopeček, J.5
|