Differences in kinetics of structurally related competitive GABAA receptor antagonists

Neuropharmacology

Volumn 52, Issue 3, 2007, Pages 873-882

  Vestergaard, Henrik Tang ^a   Cannillo, Carolina ^a   Frølund, Bente ^a   Kristiansen, Uffe ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Antagonist; GABAA receptor; Kinetics; Whole cell patch clamp

Indexed keywords

3 AMINO 2 (3 CARBOXYPROPYL) 6 (4 METHOXYPHENYL)PYRIDAZINIUM BROMIDE; 3 HYDROXY 5 (4 PIPERIDYL)ISOXAZOLE; 4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR BLOCKING AGENT; 4 AMINOBUTYRIC ACID A RECEPTOR STIMULATING AGENT; ARECAIDINE; PARTIAL AGONIST;

ANIMAL CELL; ARTICLE; BRAIN CELL; CONTROLLED STUDY; DISSOCIATION CONSTANT; DRUG BINDING SITE; DRUG POTENCY; DRUG STRUCTURE; HYDROPHOBICITY; LIPOPHILICITY; MOUSE; NONHUMAN; PARTITION COEFFICIENT; PATCH CLAMP; PRIORITY JOURNAL; RECEPTOR DOWN REGULATION;

ANIMALS; ANIMALS, NEWBORN; BINDING SITES; CELLS, CULTURED; CEREBRAL CORTEX; DRUG INTERACTIONS; ELECTRIC STIMULATION; GABA ANTAGONISTS; MEMBRANE POTENTIALS; MICE; NEURONS; PATCH-CLAMP TECHNIQUES; RECEPTORS, GABA-A; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33846856718     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2006.10.004     Document Type: Article

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