Insulin receptor substrates 1 and 2 but not Shc can activate the insulin receptor independent of insulin and induce proliferation in CHO-IR cells

Experimental Cell Research

Volumn 313, Issue 4, 2007, Pages 805-815

  Niessen, Markus ^a,b   Jaschinski, Frank ^a   Item, Flurin ^a,b   McNamara, Morgan P ^a   Spinas, Giatgen A ^a,b   Trüb, Thomas ^c  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^b ETH ZURICH   (Switzerland)

^c Ausrüstung und Logistik   (Switzerland)

Author keywords

CHO IR; Insulin receptor; Insulin receptor substrate; Insulin signalling; IRS1; IRS2; Proliferation; Shc

Indexed keywords

INSULIN; INSULIN RECEPTOR; INSULIN RECEPTOR SUBSTRATE 1; INSULIN RECEPTOR SUBSTRATE 2; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE B; PROTEIN SHC;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL PROLIFERATION; CONTROLLED STUDY; DOSE RESPONSE; GENE OVEREXPRESSION; HORMONE RECEPTOR INTERACTION; HUMAN; HUMAN CELL; LIGAND BINDING; MOLECULAR BIOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN PHOSPHORYLATION; RECEPTOR AFFINITY; SIGNAL TRANSDUCTION;

EID: 33846845184     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yexcr.2006.11.015     Document Type: Article

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