Choroid plexus epithelial monolayers - A cell culture model from porcine brain

Cerebrospinal Fluid Research

Volumn 3, Issue , 2006, Pages

  Baehr, Carsten ^a   Reichel, Valeska ^a   Fricker, Gert ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

F ACTIN; GLYCOPROTEIN P; MULTIDRUG RESISTANCE PROTEIN 1; PREALBUMIN; RHODAMINE 123; VERAPAMIL;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN; CELL ISOLATION; CEREBROSPINAL FLUID; CHOROID PLEXUS; CONTROLLED STUDY; EPITHELIUM CELL; IMMUNOFLUORESCENCE; IN VITRO STUDY; MONOLAYER CULTURE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN TRANSPORT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SWINE; WESTERN BLOTTING;

EID: 33846694629     PISSN: 17438454     EISSN: None     Source Type: Journal    
DOI: 10.1186/1743-8454-3-13     Document Type: Article

References (49)

1. Spector R Drug transport in the mammalian central nervous system: multiple complex systems. A critical analysis and commentary Pharmacology 2000 60 58-73 10.1159/000028349 10657755
2. Spector R Johanson CE The mammalian choroid plexus Sci Am 1989 261 68-74 2479097
3. Cserr HF Physiology of the choroid plexus Physiol Rev 1971 51 273-311 4930496
4. Ghersi-Egea JF Strazielle N Brain drug delivery, drug metabolism, and multidrug resistance at the choroid plexus Microsc Res Tech 2001 52 83-88 10.1002/1097-0029(20010101)52:1<83::AID-JEMT10>3.0.CO;2-N 11135451
5. el-Bacha RS Minn A Drug metabolizing enzymes in cerebrovascular endothelial cells afford a metabolic protection to the brain Cell Mol Biol 1999 45 15-23 10099836
6. Choudhuri S Cherrington NJ Li N Klaassen CD Constitutive expression of various xenobiotic and endobiotic transporter mRNAs in the choroid plexus of rats Drug Metab Dispos 2003 31 1337-1345 10.1124/ dmd.31.11.1337 14570765
7. Lee G Dallas S Hong M Bendayan R Drug transporters in the central nervous system: Brain barriers and brain parenchyma considerations Pharmacol Rev 2001 53 569-96 11734619
8. Crook RB Kasagami H Prusiner SB Culture and characterization of epithelial cells from bovine choroid plexus J Neurochem 1981 37 845-854 10.1111/j.1471-4159.1981.tb04470.x 6119356
9. Mayer SE Sanders-Bush E Sodium-dependent antiporters in choroid plexus epithelial cultures from rabbit J Neurochem 1993 60 1308-1316 10.1111/ j.1471-4159.1993.tb03291.x 8384246
10. Ramanathan VK Hui AC Brett CM Giacomini KM Primary cell culture of the rabbit choroid plexus: An experimental system to investigate membrane transport Pharm Res 1996 13 952-956 10.1023/A:1016029918091 8792439
11. Southwell BR Duan W Alcorn D Brack C Richardson SJ Kohrle J Schreiber G Thyroxine transport to the brain: Role of protein synthesis by the choroid plexus Endocrinology 1993 133 2116-2126 10.1210/en.133.5.2116 8404661
12. Strazielle N Ghersi-Egea JF Demonstration of a coupled metabolism-efflux process at the choroid plexus as a mechanism of brain protection toward xenobiotics J Neurosci 1999 19 6275-6289 10414957
13. Villalobos AR Parmelee JT Pritchard JB Functional characterization of choroid plexus epithelial cells in primary culture J Pharmacol Exp Ther 1997 282 1109-1116 9262381
14. Gath U Hakvoort A Wegener J Decker S Galla HJ Porcine choroid plexus cells in culture: Expression of polarized phenotype, maintenance of barrier properties and apical secretion of CSF-components Eur J Cell Biol 1997 74 68-78 9309392
15. Sambrook J Fritsch EF Maniatis T Molecular cloning. A laboratory manual Cold Spring Harbor Laboratory Press 1989
16. Török M Huwyler J Gutmann H Fricker G Drewe J Modulation of transendothelial permeability and expression of ATP-binding cassette transporters in cultured brain capillary endothelial cells by astrocytic factors and cell-culture conditions Exp Brain Res 2003 153 356-365 10.1007/s00221-003-1620-4 14610630
17. D'Aquila RT Bechtel LJ Videler JA Eron JJ Gorczycy P Kaplan JC Maximizing sensitivity and specificity of PCR by preamplification heating Nucleic Acid Res 1991 19 3749 328414 1852616 10.1093/nar/ 19.13.3749
18. Bradford MA Rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding Ana Biochem 1976 72 248-254 10.1016/0003-2697(76)90527-3
19. Caspers ML Diglio CA Expression of gamma-glutamyltranspeptidase in a transformed rat cerebral endothelial cell line Biochim Biophys Acta 1984 803 1-6 10.1016/0167-4889(84)90047-8 6141809
20. Hilden SA Johns CA Guggino WB Madias NE Techniques for isolation of brush-border and basolateral membrane vesicles from dog kidney cortex Biochim Biophys Acta 1989 983 77-81 10.1016/0005-2736(89)90382-9 2758052
21. Hakvoort A Haselbach M Galla HJ Active transport properties of porcine choroid plexus cells in culture Brain Res 1998 795 247-256 10.1016/ S0006-8993(98)00284-4 9622643
22. Wegener J Sieber M Galla HJ Impedance analysis of epithelial and endothelial cell monolayers cultured on gold surfaces J Biochem Biophys Meth 1996 32 151-170 10.1016/0165-022X(96)00005-X 8844323
23. Anderson J Van Itallie CM Tight junctions and the molecular basis for regulation of paracellular permeability Am J Physiol 1995 269 G467-475 7485497
24. Stauder AJM Dickson PW Aldred AR Schreiber G Mendelsohn FA Hudson P Synthesis of transthyretin (pre-albumin) mRNA in choroid plexus epithelial cells, localized by in situ hybridization in rat brain J Histochem Cytochem 1986 34 949-952 3458812
25. Archibald AL Couperwhite S Jiang ZH The porcine TTR locus maps to chromosome 6q Anim Genet 1996 27 351-353 8930078
26. De Bault LE Mitro A Species differences in the distribution of gamma-glutamyl transpeptidase in choroid plexus of lateral ventricle and microvessels of adjacent brain Histochem J 1994 26 447-452 10.1007/ BF00160058 7913922
27. Narisawa S Hasegawa H Watanabe K Millan JL Stage-specific expression of alkaline phosphatase during neuronal development in the mouse Dev Dyn 1994 201 227-235 7533563
28. Johanson CE Ventricles and cerebrospinal fluid Neuroscience in Medicine Philadelphia: J.B. Lippincott Company Conn P 1995 171-196
29. Hakvoort A Haselbach M Wegener J Hoheisel D Galla HJ The polarity of choroid plexus epithelial cells in vitro is improved in serum free medium J Neurochem 1998 71 1141-1150 9721739
30. Saito Y Wright EM Bicarbonate transport across the frog choroid plexus and its control by cyclic nucleotides J Physiol 1983 336 635-648 1198989 6308232
31. Villalobos AR Miller DS Renfro JL Transepithelial organic anion transport by shark choroid plexus Am J Physiol 2002 282 R1308-1316
32. Angelow S Zeni P Galla HJ Usefulness and limitation of primary cultured porcine choroid plexus epithelial cells as an in vitro model to study transport at the blood CSF barrier Adv Drug Deliv Rev 2004 56 1859-1873 10.1016/j.addr.2004.07.012 15381337
33. Begley DJ ABC transporters and the blood-brain barrier Curr Pharm Des 2004 10 1295-312 10.2174/1381612043384844 15134482
34. Nishino J Suzuki H Sugiyama D Kitazawa T Ito K Hanano M Sugiyama Y Trans-epithelial transport of organic anions across the choroid plexus: possible involvement of organic anion transporter and multidrug resistance-associated protein J Pharmacol Exp Ther 1999 290 289-94 10381789
35. Rao VV Dahlheimer JL Bardgett ME Snyder AZ Finch RA Sartorelli AC Piwnica-Worms D Choroid plexus epithelial expression of MDR1 P glycoprotein and multidrug resistance-associated protein contribute to the blood-cerebrospinal-fluid drug-permeability barrier Proc Natl Acad Sci USA 1999 96 3900-3905 22392 10097135 10.1073/pnas.96.7.3900
36. Scheffer GL Kool M Heijn M de Haas M Pijnenborg AC Wijnholds J van Helvoort A de Jong MC Hooijberg JH Mol CA van der Linden M de Vree JM van der Valk P Elferink RP Borst P Scheper RJ Specific detection of multidrug resistance proteins MRP1, MRP2, MRP3, MRP5, and MDR3 P-glycoprotein with a panel of monoclonal antibodies Cancer Res 2000 60 5269-5277 11016657
37. Baehr CH Fricker G Miller DS Fluorescein-Methotrexate transport in dogfish shark (Squalus acanthias) choroid plexus Am J Physiol Regul Integr Comp Physiol 2006 291 R464-472 16914433
38. Shen H Keep RF Hu Y Smith DE PEPT2 (Slc15a2)-mediated unidirectional transport of cefadroxil from cerebrospinal fluid into choroid plexus J Pharmacol Exp Ther 2005 315 1101-1108 10.1124/jpet.105.090654 16107517
39. Redzic ZB Isakovic AJ Misirlic Dencic ST Popadic D Segal MB Uneven distribution of nucleoside transporters and intracellular enzymatic degradation prevent transport of intact [14C] adenosine across the sheep choroid plexus epithelium as a monolayer in primary culture Cerebrospinal Fluid Res 2006 3 4 1450313 16571111 10.1186/1743-8454-3-4
40. Fukushima H Fujimoto M Ide M Quantitative detection of blood-brain barrier-associated enzymes in cultured endothelial cells of porcine brain microvessels In Vitro Cell Dev Biol 1990 26 612-620 1972703
41. Cordon-Cardo C O'Brien JP Casals D Rittman-Grauer L Biedler JL Melamed MR Bertino JR Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites Proc Natl Acad Sci USA 1989 86 695-698 286540 2563168 10.1073/pnas.86.2.695
42. Schinkel AH Smit JJ van Tellingen O Beijnen JH Wagenaar E van Deemter L Mol CA van der Valk MA Robanus-Maandag EC te Riele HP Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs Cell 1994 77 491-502 10.1016/0092-8674(94)90212-7 7910522
43. Miller DS Nobmann SN Gutmann H Toeroek M Drewe J Fricker G Xenobiotic transport across isolated brain microvessels studied by confocal microscopy Mol Pharmacol 2000 58 1357-1367 11093774
44. Fricker G Miller DS Modulation of drug transporters at the blood-brain barrier Pharmacology 2004 70 169-76 10.1159/000075545 15001817
45. Gao B Meier PJ Organic anion transport across the choroid plexus Microsc Res Tech 2001 52 60-64 10.1002/ 1097-0029(20010101)52:1<60::AID-JEMT8>3.0.CO;2-C 11135449
46. Chen J Balmaceda C Bruce JN Sisti MB Huang M Cheung YK McKhann GM Goodman RR Fine RL Tamoxifen paradoxically decreases paclitaxel deposition into cerebrospinal fluid of brain tumor patients J Neurooncol 2006 76 85-92 10.1007/s11060-005-4171-7 16402278
47. Anthonypillai C Sanderson RN Gibbs JE Thomas SA The distribution of the HIV protease inhibitor, ritonavir, to the brain, cerebrospinal fluid, and choroid plexuses of the guinea pig J Pharmacol Exp Ther 2004 308 912-920 10.1124/jpet.103.060210 14634041
48. Breen CM Sykes DB Baehr C Fricker G Miller DS Fluorescein-methotrexate transport in rat choroid plexus analyzed using confocal microscopy Am J Physiol Renal Physiol 2004 287 F562-569 10.1152/ajprenal.00045.2003 15126245
49. Wijnholds J deLange EC Scheffer GL van den Berg DJ Mol CA van der Valk M Schinkel AH Scheper RJ Breimer DD Borst P Multidrug resistance protein 1 protects the choroid plexus epithelium and contributes to the blood-cerebrospinal fluid barrier J Clin Invest 2000 105 279-285 377447 10675353