-
1
-
-
0035856920
-
Global and societal implications of the diabetes epidemic
-
Zimmet P, Alberti KG, Shaw J (2001) Global and societal implications of the diabetes epidemic. Nature 414:782-787
-
(2001)
Nature
, vol.414
, pp. 782-787
-
-
Zimmet, P.1
Alberti, K.G.2
Shaw, J.3
-
2
-
-
0035799806
-
Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance
-
Tuomilehto J, Lindstrom J, Eriksson JG, Valle TT, Hamalainen H, Ilanne-Parikka P, Keinanen-Kiukaanniemi S, Laakso M, Louheranta A, Rastas M, Salminen V, Uusitupa M (2001) Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance. N Engl J Med 344:1343-1350
-
(2001)
N Engl J Med
, vol.344
, pp. 1343-1350
-
-
Tuomilehto, J.1
Lindstrom, J.2
Eriksson, J.G.3
Valle, T.T.4
Hamalainen, H.5
Ilanne-Parikka, P.6
Keinanen-Kiukaanniemi, S.7
Laakso, M.8
Louheranta, A.9
Rastas, M.10
Salminen, V.11
Uusitupa, M.12
-
3
-
-
0345707499
-
The Finnish Diabetes Prevention Study (DPS): Lifestyle intervention and 3-year results on diet and physical activity
-
Lindstrom J, Louheranta A, Mannelin M, Rastas M, Salminen V, Eriksson J, Uusitupa M, Tuomilehto J (2003) The Finnish Diabetes Prevention Study (DPS): lifestyle intervention and 3-year results on diet and physical activity. Diabetes Care 26:3230-3236
-
(2003)
Diabetes Care
, vol.26
, pp. 3230-3236
-
-
Lindstrom, J.1
Louheranta, A.2
Mannelin, M.3
Rastas, M.4
Salminen, V.5
Eriksson, J.6
Uusitupa, M.7
Tuomilehto, J.8
-
4
-
-
33646584516
-
An update on the Diabetes Prevention Program
-
Ratner RE (2006) An update on the Diabetes Prevention Program. Endocr Pract 12(Suppl 1):20-24
-
(2006)
Endocr Pract
, vol.12
, Issue.SUPPL. 1
, pp. 20-24
-
-
Ratner, R.E.1
-
5
-
-
0030935652
-
Effects of diet and exercise in preventing NIDDM in people with impaired glucose tolerance. The Da Qing IGT and Diabetes Study
-
Pan XR, Li GW, Hu YH, Wang JX, Yang WY, An ZX, Hu ZX, Lin J, Xiao JZ, Cao HB, Liu PA, Jiang XG, Jiang YY, Wang JP, Zheng H, Zhang H, Bennett PH, Howard BV (1997) Effects of diet and exercise in preventing NIDDM in people with impaired glucose tolerance. The Da Qing IGT and Diabetes Study. Diabetes Care 20:537-544
-
(1997)
Diabetes Care
, vol.20
, pp. 537-544
-
-
Pan, X.R.1
Li, G.W.2
Hu, Y.H.3
Wang, J.X.4
Yang, W.Y.5
An, Z.X.6
Hu, Z.X.7
Lin, J.8
Xiao, J.Z.9
Cao, H.B.10
Liu, P.A.11
Jiang, X.G.12
Jiang, Y.Y.13
Wang, J.P.14
Zheng, H.15
Zhang, H.16
Bennett, P.H.17
Howard, B.V.18
-
6
-
-
0037034257
-
Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin
-
Knowler WC, Barrett-Connor E, Fowler SE, Hamman RF, Lachin JM, Walker EA, Nathan DM (2002) Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med 346:393-403
-
(2002)
N Engl J Med
, vol.346
, pp. 393-403
-
-
Knowler, W.C.1
Barrett-Connor, E.2
Fowler, S.E.3
Hamman, R.F.4
Lachin, J.M.5
Walker, E.A.6
Nathan, D.M.7
-
7
-
-
31844452061
-
The Indian Diabetes Prevention Programme shows that lifestyle modification and metformin prevent type 2 diabetes in Asian Indian subjects with impaired glucose tolerance (IDPP-1)
-
Ramachandran A, Snehalatha C, Mary S, Mukesh B, Bhaskar AD, Vijay V (2006) The Indian Diabetes Prevention Programme shows that lifestyle modification and metformin prevent type 2 diabetes in Asian Indian subjects with impaired glucose tolerance (IDPP-1). Diabetologia 49:289-297
-
(2006)
Diabetologia
, vol.49
, pp. 289-297
-
-
Ramachandran, A.1
Snehalatha, C.2
Mary, S.3
Mukesh, B.4
Bhaskar, A.D.5
Vijay, V.6
-
8
-
-
18644371780
-
Prevention of type 2 diabetes
-
Laakso M (2005) Prevention of type 2 diabetes. Curr Mol Med 5:365-574
-
(2005)
Curr Mol Med
, vol.5
, pp. 365-574
-
-
Laakso, M.1
-
9
-
-
0037097039
-
Acarbose for prevention of type 2 diabetes mellitus: The STOP-NIDDM randomised trial
-
Chiasson JL, Josse RG, Gomis R, Hanefeld M, Karasik A, Laakso M (2002) Acarbose for prevention of type 2 diabetes mellitus: the STOP-NIDDM randomised trial. Lancet 359:2072-2077
-
(2002)
Lancet
, vol.359
, pp. 2072-2077
-
-
Chiasson, J.L.1
Josse, R.G.2
Gomis, R.3
Hanefeld, M.4
Karasik, A.5
Laakso, M.6
-
10
-
-
1042303480
-
XENical in the prevention of diabetes in obese subjects (XENDOS) study: A randomized study of orlistat as an adjunct to lifestyle changes for the prevention of type 2 diabetes in obese patients
-
Torgerson JS, Hauptman J, Boldrin MN, Sjostrom L (2004) XENical in the prevention of diabetes in obese subjects (XENDOS) study: a randomized study of orlistat as an adjunct to lifestyle changes for the prevention of type 2 diabetes in obese patients. Diabetes Care 27:155-161
-
(2004)
Diabetes Care
, vol.27
, pp. 155-161
-
-
Torgerson, J.S.1
Hauptman, J.2
Boldrin, M.N.3
Sjostrom, L.4
-
11
-
-
15944395414
-
Prevention of type 2 diabetes with troglitazone in the Diabetes Prevention Program
-
Knowler WC, Hamman RF, Edelstein SL, Barrett-Connor E, Ehrmann DA, Walker EA, Fowler SE, Nathan DM, Kahn SE (2005) Prevention of type 2 diabetes with troglitazone in the Diabetes Prevention Program. Diabetes 54:1150-1156
-
(2005)
Diabetes
, vol.54
, pp. 1150-1156
-
-
Knowler, W.C.1
Hamman, R.F.2
Edelstein, S.L.3
Barrett-Connor, E.4
Ehrmann, D.A.5
Walker, E.A.6
Fowler, S.E.7
Nathan, D.M.8
Kahn, S.E.9
-
12
-
-
19944429248
-
Physical activity in the prevention of type 2 diabetes: The Finnish diabetes prevention study
-
Laaksonen DE, Lindstrom J, Lakka TA, Eriksson JG, Niskanen L, Wikstrom K, Aunola S, Keinanen-Kiukaanniemi S, Laakso M, Valle TT, Ilanne-Parikka P, Louheranta A, Hamalainen H, Rastas M, Salminen V, Cepaitis Z, Hakumaki M, Kaikkonen H, Harkonen P, Sundvall J, Tuomilehto J, Uusitupa M (2005) Physical activity in the prevention of type 2 diabetes: the Finnish diabetes prevention study. Diabetes 54:158-165
-
(2005)
Diabetes
, vol.54
, pp. 158-165
-
-
Laaksonen, D.E.1
Lindstrom, J.2
Lakka, T.A.3
Eriksson, J.G.4
Niskanen, L.5
Wikstrom, K.6
Aunola, S.7
Keinanen-Kiukaanniemi, S.8
Laakso, M.9
Valle, T.T.10
Ilanne-Parikka, P.11
Louheranta, A.12
Hamalainen, H.13
Rastas, M.14
Salminen, V.15
Cepaitis, Z.16
Hakumaki, M.17
Kaikkonen, H.18
Harkonen, P.19
Sundvall, J.20
Tuomilehto, J.21
Uusitupa, M.22
more..
-
13
-
-
18844390525
-
Lifestyle strategies for weight control: Experience from the Finnish Diabetes Prevention Study
-
Lindstrom J, Peltonen M, Tuomilehto J (2005) Lifestyle strategies for weight control: experience from the Finnish Diabetes Prevention Study. Proc Nutr Soc 64:81-88
-
(2005)
Proc Nutr Soc
, vol.64
, pp. 81-88
-
-
Lindstrom, J.1
Peltonen, M.2
Tuomilehto, J.3
-
14
-
-
23644443235
-
Role of insulin secretion and sensitivity in the evolution of type 2 diabetes in the diabetes prevention program: Effects of lifestyle intervention and metformin
-
Kitabchi AE, Temprosa M, Knowler WC, Kahn SE, Fowler SE, Haffner SM, Andres R, Saudek C, Edelstein SL, Arakaki R,Murphy MB, Shamoon H (2005) Role of insulin secretion and sensitivity in the evolution of type 2 diabetes in the diabetes prevention program: effects of lifestyle intervention and metformin. Diabetes 54:2404-2414
-
(2005)
Diabetes
, vol.54
, pp. 2404-2414
-
-
Kitabchi, A.E.1
Temprosa, M.2
Knowler, W.C.3
Kahn, S.E.4
Fowler, S.E.5
Haffner, S.M.6
Andres, R.7
Saudek, C.8
Edelstein, S.L.9
Arakaki, R.10
Murphy, M.B.11
Shamoon, H.12
-
15
-
-
19944426903
-
Predictors of and longitudinal changes in insulin sensitivity and secretion preceding onset of type 2 diabetes
-
Lyssenko V, Almgren P, Anevski D, Perfekt R, Lahti K, Nissen M, Isomaa B, Forsen B, Homstrom N, Saloranta C, Taskinen MR, Groop L, Tuomi T (2005) Predictors of and longitudinal changes in insulin sensitivity and secretion preceding onset of type 2 diabetes. Diabetes 54:166-174
-
(2005)
Diabetes
, vol.54
, pp. 166-174
-
-
Lyssenko, V.1
Almgren, P.2
Anevski, D.3
Perfekt, R.4
Lahti, K.5
Nissen, M.6
Isomaa, B.7
Forsen, B.8
Homstrom, N.9
Saloranta, C.10
Taskinen, M.R.11
Groop, L.12
Tuomi, T.13
-
16
-
-
0032991552
-
Characterization of single-nucleotide polymorphisms in coding regions of human genes
-
CargillM, Altshuler D, Ireland J, Sklar P, Ardlie K, Patil N, Shaw N, Lane CR, Lim EP, Kalyanaraman N, Nemesh J, Ziaugra L, Friedland L, Rolfe A, Warrington J, Lipshutz R, Daley GQ, Lander ES (1999) Characterization of single-nucleotide polymorphisms in coding regions of human genes. Nat Genet 22:231-238
-
(1999)
Nat Genet
, vol.22
, pp. 231-238
-
-
Cargill, M.1
Altshuler, D.2
Ireland, J.3
Sklar, P.4
Ardlie, K.5
Patil, N.6
Shaw, N.7
Lane, C.R.8
Lim, E.P.9
Kalyanaraman, N.10
Nemesh, J.11
Ziaugra, L.12
Friedland, L.13
Rolfe, A.14
Warrington, J.15
Lipshutz, R.16
Daley, G.Q.17
Lander, E.S.18
-
17
-
-
12344279952
-
Genetic factors in type 2 diabetes: The end of the beginning?
-
O'Rahilly S, Barroso I, Wareham NJ (2005) Genetic factors in type 2 diabetes: the end of the beginning? Science 307:370-373
-
(2005)
Science
, vol.307
, pp. 370-373
-
-
O'Rahilly, S.1
Barroso, I.2
Wareham, N.J.3
-
18
-
-
14844351853
-
Genetics of type 2 diabetes mellitus: Status and perspectives
-
Hansen L, Pedersen O (2005) Genetics of type 2 diabetes mellitus: status and perspectives. Diabetes Obes Metab 7:122-135
-
(2005)
Diabetes Obes Metab
, vol.7
, pp. 122-135
-
-
Hansen, L.1
Pedersen, O.2
-
19
-
-
32544451924
-
-
Grant SF, Thorleifsson G, Reynisdottir I, Benediktsson R, Manolescu A, Sainz J, Helgason A, Stefansson H, Emilsson V, Helgadottir A, Styrkarsdottir U, Magnusson KP, Walters GB, Palsdottir E, Jonsdottir T, Gudmundsdottir T, Gylfason A, Saemundsdottir J, Wilensky RL, Reilly MP, Rader DJ, Bagger Y, Christiansen C, Gudnason V, Sigurdsson G, Thorsteinsdottir U, Gulcher JR, Kong A, Stefansson K (2006) Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes. Nat Genet 38:320-323
-
Grant SF, Thorleifsson G, Reynisdottir I, Benediktsson R, Manolescu A, Sainz J, Helgason A, Stefansson H, Emilsson V, Helgadottir A, Styrkarsdottir U, Magnusson KP, Walters GB, Palsdottir E, Jonsdottir T, Gudmundsdottir T, Gylfason A, Saemundsdottir J, Wilensky RL, Reilly MP, Rader DJ, Bagger Y, Christiansen C, Gudnason V, Sigurdsson G, Thorsteinsdottir U, Gulcher JR, Kong A, Stefansson K (2006) Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes. Nat Genet 38:320-323
-
-
-
-
20
-
-
33746075560
-
TCF7L2 polymorphisms and progression to diabetes in the Diabetes Prevention Program
-
Florez JC, Jablonski KA, Bayley N, Pollin TI, de Bakker PI, Shuldiner AR, Knowler WC, Nathan DM, Altshuler D (2006) TCF7L2 polymorphisms and progression to diabetes in the Diabetes Prevention Program. N Engl J Med 355:241-250
-
(2006)
N Engl J Med
, vol.355
, pp. 241-250
-
-
Florez, J.C.1
Jablonski, K.A.2
Bayley, N.3
Pollin, T.I.4
de Bakker, P.I.5
Shuldiner, A.R.6
Knowler, W.C.7
Nathan, D.M.8
Altshuler, D.9
-
21
-
-
33750584981
-
Polymorphisms in the transcription factor 7-like 2 (TCF7L2) gene are associated with type 2 diabetes in the Amish: Replication and evidence for a role in both insulin secretion and insulin resistance
-
Damcott CM, Pollin TI, Reinhart LJ, Ott SH, Shen H, Silver KD, Mitchell BD, Shuldiner AR (2006) Polymorphisms in the transcription factor 7-like 2 (TCF7L2) gene are associated with type 2 diabetes in the Amish: replication and evidence for a role in both insulin secretion and insulin resistance. Diabetes 55:2654-2659
-
(2006)
Diabetes
, vol.55
, pp. 2654-2659
-
-
Damcott, C.M.1
Pollin, T.I.2
Reinhart, L.J.3
Ott, S.H.4
Shen, H.5
Silver, K.D.6
Mitchell, B.D.7
Shuldiner, A.R.8
-
22
-
-
33750587754
-
Association of transcription factor 7-like 2 (TCF7L2) variants with type 2 diabetes in a Finnish sample
-
Scott LJ, Bonnycastle LL, Willer CJ, Sprau AG, Jackson AU, Narisu N, Duren WL, Chines PS, Stringham HM, Erdos MR, Valle TT, Tuomilehto J, Bergman RN, Mohlke KL, Collins FS, Boehnke M (2006) Association of transcription factor 7-like 2 (TCF7L2) variants with type 2 diabetes in a Finnish sample. Diabetes 55:2649-2653
-
(2006)
Diabetes
, vol.55
, pp. 2649-2653
-
-
Scott, L.J.1
Bonnycastle, L.L.2
Willer, C.J.3
Sprau, A.G.4
Jackson, A.U.5
Narisu, N.6
Duren, W.L.7
Chines, P.S.8
Stringham, H.M.9
Erdos, M.R.10
Valle, T.T.11
Tuomilehto, J.12
Bergman, R.N.13
Mohlke, K.L.14
Collins, F.S.15
Boehnke, M.16
-
23
-
-
33750594321
-
Variant of transcription factor 7-like 2 (TCF7L2) gene and the risk of type 2 diabetes in large cohorts of U.S. women and men
-
Zhang C, Qi L, Hunter DJ, Meigs JB, Manson JE, van Dam RM, Hu FB (2006) Variant of transcription factor 7-like 2 (TCF7L2) gene and the risk of type 2 diabetes in large cohorts of U.S. women and men. Diabetes 55:2645-2648
-
(2006)
Diabetes
, vol.55
, pp. 2645-2648
-
-
Zhang, C.1
Qi, L.2
Hunter, D.J.3
Meigs, J.B.4
Manson, J.E.5
van Dam, R.M.6
Hu, F.B.7
-
24
-
-
33750602980
-
Association analysis of 6,736 U.K. subjects provides replication and confirms TCF7L2 as a type 2 diabetes susceptibility gene with a substantial effect on individual risk
-
Groves CJ, Zeggini E, Minton J, Frayling TM, Weedon MN, Rayner NW, Hitman GA, Walker M, Wiltshire S, Hattersley AT, McCarthy MI (2006) Association analysis of 6,736 U.K. subjects provides replication and confirms TCF7L2 as a type 2 diabetes susceptibility gene with a substantial effect on individual risk. Diabetes 55:2640-2644
-
(2006)
Diabetes
, vol.55
, pp. 2640-2644
-
-
Groves, C.J.1
Zeggini, E.2
Minton, J.3
Frayling, T.M.4
Weedon, M.N.5
Rayner, N.W.6
Hitman, G.A.7
Walker, M.8
Wiltshire, S.9
Hattersley, A.T.10
McCarthy, M.I.11
-
26
-
-
23944482391
-
Single nucleotide polymorphisms that influence lipid metabolism: Interaction with dietary factors
-
Corella D, Ordovas JM (2005) Single nucleotide polymorphisms that influence lipid metabolism: interaction with dietary factors. Annu Rev Nutr 25:341-390
-
(2005)
Annu Rev Nutr
, vol.25
, pp. 341-390
-
-
Corella, D.1
Ordovas, J.M.2
-
27
-
-
0037797302
-
Genetic variation and the lipid response to dietary intervention: A systematic review
-
Masson LF, McNeill G, Avenell A (2003) Genetic variation and the lipid response to dietary intervention: a systematic review. Am J Clin Nutr 77:1098-1111
-
(2003)
Am J Clin Nutr
, vol.77
, pp. 1098-1111
-
-
Masson, L.F.1
McNeill, G.2
Avenell, A.3
-
29
-
-
14044254272
-
The common - 866G/A polymorphism in the promoter region of the UCP-2 gene is associated with reduced risk of type 2 diabetes in Caucasians from Italy
-
Bulotta A, Ludovico O, Coco A, Di Paola R, Quattrone A, Carella M, Pellegrini F, Prudente S, Trischitta V (2005) The common - 866G/A polymorphism in the promoter region of the UCP-2 gene is associated with reduced risk of type 2 diabetes in Caucasians from Italy. J Clin Endocrinol Metab 90:1176-1180
-
(2005)
J Clin Endocrinol Metab
, vol.90
, pp. 1176-1180
-
-
Bulotta, A.1
Ludovico, O.2
Coco, A.3
Di Paola, R.4
Quattrone, A.5
Carella, M.6
Pellegrini, F.7
Prudente, S.8
Trischitta, V.9
-
30
-
-
33646339674
-
The -8503 G/A polymorphism of the adiponectin receptor 1 gene is associated with insulin sensitivity dependent on adiposity
-
Kantartzis K, Fritsche A, Machicao F, Haring HU, Stefan N (2006) The -8503 G/A polymorphism of the adiponectin receptor 1 gene is associated with insulin sensitivity dependent on adiposity. Diabetes Care 29:464
-
(2006)
Diabetes Care
, vol.29
, pp. 464
-
-
Kantartzis, K.1
Fritsche, A.2
Machicao, F.3
Haring, H.U.4
Stefan, N.5
-
31
-
-
27744492082
-
Polymorphisms in the gene encoding adiponectin receptor 1 are associated with insulin resistance and high liver fat
-
Stefan N, Machicao F, Staiger H, Machann J, Schick F, Tschritter O, Spieth C, Weigert C, Fritsche A, Stumvoll M, Haring HU (2005) Polymorphisms in the gene encoding adiponectin receptor 1 are associated with insulin resistance and high liver fat. Diabetologia 48:2282-2291
-
(2005)
Diabetologia
, vol.48
, pp. 2282-2291
-
-
Stefan, N.1
Machicao, F.2
Staiger, H.3
Machann, J.4
Schick, F.5
Tschritter, O.6
Spieth, C.7
Weigert, C.8
Fritsche, A.9
Stumvoll, M.10
Haring, H.U.11
-
32
-
-
33746367157
-
Alpha2-Heremans-Schmid glycoprotein/fetuin-A is associated with insulin resistance and fat accumulation in the liver in humans
-
Stefan N, Hennige AM, Staiger H, Machann J, Schick F, Krober SM, Machicao F, Fritsche A, Haring HU (2006) Alpha2-Heremans-Schmid glycoprotein/fetuin-A is associated with insulin resistance and fat accumulation in the liver in humans. Diabetes Care 29:853-857
-
(2006)
Diabetes Care
, vol.29
, pp. 853-857
-
-
Stefan, N.1
Hennige, A.M.2
Staiger, H.3
Machann, J.4
Schick, F.5
Krober, S.M.6
Machicao, F.7
Fritsche, A.8
Haring, H.U.9
-
33
-
-
33644794968
-
The association between plasma adiponectin and insulin sensitivity in humans depends on obesity
-
Kantartzis K, Fritsche A, Tschritter O, Thamer C, Haap M, Schafer S, Stumvoll M, Haring HU, Stefan N (2005) The association between plasma adiponectin and insulin sensitivity in humans depends on obesity. Obes Res 13:1683-1691
-
(2005)
Obes Res
, vol.13
, pp. 1683-1691
-
-
Kantartzis, K.1
Fritsche, A.2
Tschritter, O.3
Thamer, C.4
Haap, M.5
Schafer, S.6
Stumvoll, M.7
Haring, H.U.8
Stefan, N.9
-
34
-
-
31544483636
-
New imaging techniques of fat, muscle and liver within the context of determining insulin sensitivity
-
Stefan N, Machann J, Schick F, Claussen CD, Thamer C, Fritsche A, Haring HU (2005) New imaging techniques of fat, muscle and liver within the context of determining insulin sensitivity. Horm Res 64(Suppl 3):38-44
-
(2005)
Horm Res
, vol.64
, Issue.SUPPL. 3
, pp. 38-44
-
-
Stefan, N.1
Machann, J.2
Schick, F.3
Claussen, C.D.4
Thamer, C.5
Fritsche, A.6
Haring, H.U.7
-
35
-
-
33745776070
-
Association of sequence variations in the gene encoding adiponectin receptor 1 (ADIPOR1) with body size and insulin levels. The Finnish Diabetes Prevention Study
-
Siitonen N, Pulkkinen L, Mager U, Lindstrom J, Eriksson JG, Valle TT, Hamalainen H, Ilanne-Parikka P, Keinanen-Kiukaanniemi S, Tuomilehto J, Laakso M, Uusitupa M (2006) Association of sequence variations in the gene encoding adiponectin receptor 1 (ADIPOR1) with body size and insulin levels. The Finnish Diabetes Prevention Study. Diabetologia 49:1795-1805
-
(2006)
Diabetologia
, vol.49
, pp. 1795-1805
-
-
Siitonen, N.1
Pulkkinen, L.2
Mager, U.3
Lindstrom, J.4
Eriksson, J.G.5
Valle, T.T.6
Hamalainen, H.7
Ilanne-Parikka, P.8
Keinanen-Kiukaanniemi, S.9
Tuomilehto, J.10
Laakso, M.11
Uusitupa, M.12
-
36
-
-
0036320603
-
The peroxisome proliferator-activated receptor-gamma2 Pro12Ala polymorphism
-
Stumvoll M, Haring H (2002) The peroxisome proliferator-activated receptor-gamma2 Pro12Ala polymorphism. Diabetes 51:2341-2347
-
(2002)
Diabetes
, vol.51
, pp. 2341-2347
-
-
Stumvoll, M.1
Haring, H.2
-
37
-
-
0035032780
-
Effect of experimental elevation of free fatty acids on insulin secretion and insulin sensitivity in healthy carriers of the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma2 gene
-
Stefan N, Fritsche A, Haring H, Stumvoll M (2001) Effect of experimental elevation of free fatty acids on insulin secretion and insulin sensitivity in healthy carriers of the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma2 gene. Diabetes 50:1143-1148
-
(2001)
Diabetes
, vol.50
, pp. 1143-1148
-
-
Stefan, N.1
Fritsche, A.2
Haring, H.3
Stumvoll, M.4
-
38
-
-
2442676735
-
The Gly1057Asp polymorphism in IRS-2 interacts with obesity to affect beta cell function
-
Stefan N, Fritsche A, Machicao F, Tschritter O, Haring HU, Stumvoll M (2004) The Gly1057Asp polymorphism in IRS-2 interacts with obesity to affect beta cell function. Diabetologia 47:759-761
-
(2004)
Diabetologia
, vol.47
, pp. 759-761
-
-
Stefan, N.1
Fritsche, A.2
Machicao, F.3
Tschritter, O.4
Haring, H.U.5
Stumvoll, M.6
-
39
-
-
0036329369
-
Association of the Pro12Ala polymorphism in the PPAR-gamma2 gene with 3-year incidence of type 2 diabetes and body weight change in the Finnish Diabetes Prevention Study
-
Lindi VI, Uusitupa MI, Lindstrom J, Louheranta A, Eriksson JG, Valle TT, Hamalainen H, Ilanne-Parikka P, Keinanen-Kiukaanniemi S, Laakso M, Tuomilehto J (2002) Association of the Pro12Ala polymorphism in the PPAR-gamma2 gene with 3-year incidence of type 2 diabetes and body weight change in the Finnish Diabetes Prevention Study. Diabetes 51:2581-2586
-
(2002)
Diabetes
, vol.51
, pp. 2581-2586
-
-
Lindi, V.I.1
Uusitupa, M.I.2
Lindstrom, J.3
Louheranta, A.4
Eriksson, J.G.5
Valle, T.T.6
Hamalainen, H.7
Ilanne-Parikka, P.8
Keinanen-Kiukaanniemi, S.9
Laakso, M.10
Tuomilehto, J.11
-
40
-
-
0035461855
-
Genetic variation in the peroxisome proliferator-activated receptor-gamma2 gene (Pro12Ala) affects metabolic responses to weight loss and subsequent weight regain
-
Nicklas BJ, van Rossum EF, Berman DM, Ryan AS, Dennis KE, Shuldiner AR (2001) Genetic variation in the peroxisome proliferator-activated receptor-gamma2 gene (Pro12Ala) affects metabolic responses to weight loss and subsequent weight regain. Diabetes 50:2172-2176
-
(2001)
Diabetes
, vol.50
, pp. 2172-2176
-
-
Nicklas, B.J.1
van Rossum, E.F.2
Berman, D.M.3
Ryan, A.S.4
Dennis, K.E.5
Shuldiner, A.R.6
-
41
-
-
9644255938
-
Endurance training-induced changes in the insulin response to oral glucose are associated with the peroxisome proliferator-activated receptor-gamma2 Pro12Ala genotype in men but not in women
-
Weiss EP, Kulaputana O, Ghiu IA, Brandauer J, Wohn CR, Phares DA, Shuldiner AR, Hagberg JM (2005) Endurance training-induced changes in the insulin response to oral glucose are associated with the peroxisome proliferator-activated receptor-gamma2 Pro12Ala genotype in men but not in women. Metabolism 54:97-102
-
(2005)
Metabolism
, vol.54
, pp. 97-102
-
-
Weiss, E.P.1
Kulaputana, O.2
Ghiu, I.A.3
Brandauer, J.4
Wohn, C.R.5
Phares, D.A.6
Shuldiner, A.R.7
Hagberg, J.M.8
-
42
-
-
0033820424
-
Impaired capacity to lose visceral adipose tissue during weight reduction in obese postmenopausal women with the Trp64Arg beta3-adrenoceptor gene variant
-
Tchernof A, Starling RD, Turner A, Shuldiner AR, Walston JD, Silver K, Poehlman ET (2000) Impaired capacity to lose visceral adipose tissue during weight reduction in obese postmenopausal women with the Trp64Arg beta3-adrenoceptor gene variant. Diabetes 49:1709-1713
-
(2000)
Diabetes
, vol.49
, pp. 1709-1713
-
-
Tchernof, A.1
Starling, R.D.2
Turner, A.3
Shuldiner, A.R.4
Walston, J.D.5
Silver, K.6
Poehlman, E.T.7
-
43
-
-
21644460163
-
Gene-diet interaction in relation to the prevention of obesity and type 2 diabetes: Evidence from the Finnish Diabetes Prevention Study
-
Uusitupa M (2005) Gene-diet interaction in relation to the prevention of obesity and type 2 diabetes: evidence from the Finnish Diabetes Prevention Study. Nutr Metab Cardiovasc Dis 15:225-233
-
(2005)
Nutr Metab Cardiovasc Dis
, vol.15
, pp. 225-233
-
-
Uusitupa, M.1
-
44
-
-
4544359740
-
Association between a deletion/insertion polymorphism in the alpha2B-adrenergic receptor gene and insulin secretion and Type 2 diabetes. The Finnish Diabetes Prevention Study
-
Siitonen N, Lindstrom J, Eriksson J, Valle TT, Hamalainen H, Ilanne-Parikka P, Keinanen-Kiukaanniemi S, Tuomilehto J, Laakso M, Uusitupa M (2004) Association between a deletion/insertion polymorphism in the alpha2B-adrenergic receptor gene and insulin secretion and Type 2 diabetes. The Finnish Diabetes Prevention Study. Diabetologia 47:1416-1424
-
(2004)
Diabetologia
, vol.47
, pp. 1416-1424
-
-
Siitonen, N.1
Lindstrom, J.2
Eriksson, J.3
Valle, T.T.4
Hamalainen, H.5
Ilanne-Parikka, P.6
Keinanen-Kiukaanniemi, S.7
Tuomilehto, J.8
Laakso, M.9
Uusitupa, M.10
-
45
-
-
33744781059
-
Association of the Leu72Met polymorphism of the ghrelin gene with the risk of Type 2 diabetes in subjects with impaired glucose tolerance in the Finnish Diabetes Prevention Study
-
Mager U, Lindi V, Lindstrom J, Eriksson JG, Valle TT, Hamalainen H, Ilanne-Parikka P, Keinanen-Kiukaanniemi S, Tuomilehto J, Laakso M, Pulkkinen L, Uusitupa M (2006) Association of the Leu72Met polymorphism of the ghrelin gene with the risk of Type 2 diabetes in subjects with impaired glucose tolerance in the Finnish Diabetes Prevention Study. Diabet Med 23:685-689
-
(2006)
Diabet Med
, vol.23
, pp. 685-689
-
-
Mager, U.1
Lindi, V.2
Lindstrom, J.3
Eriksson, J.G.4
Valle, T.T.5
Hamalainen, H.6
Ilanne-Parikka, P.7
Keinanen-Kiukaanniemi, S.8
Tuomilehto, J.9
Laakso, M.10
Pulkkinen, L.11
Uusitupa, M.12
-
46
-
-
26844513588
-
Effect of the Pro12Ala polymorphism of the PPARg2 gene on serum adiponectin changes
-
Mousavinasab F, Tahtinen T, Jokelainen J, Koskela P, Vanhala M, Oikarinen J, Keinanen-Kiukaanniemi S, Laakso M (2005) Effect of the Pro12Ala polymorphism of the PPARg2 gene on serum adiponectin changes. Endocrine 27:307-309
-
(2005)
Endocrine
, vol.27
, pp. 307-309
-
-
Mousavinasab, F.1
Tahtinen, T.2
Jokelainen, J.3
Koskela, P.4
Vanhala, M.5
Oikarinen, J.6
Keinanen-Kiukaanniemi, S.7
Laakso, M.8
-
47
-
-
0035123646
-
Evidence for gene-nutrient interaction at the PPARgamma locus
-
Luan J, Browne PO, Harding AH, Halsall DJ, O'Rahilly S, Chatterjee VK, Wareham NJ (2001) Evidence for gene-nutrient interaction at the PPARgamma locus. Diabetes 50:686-689
-
(2001)
Diabetes
, vol.50
, pp. 686-689
-
-
Luan, J.1
Browne, P.O.2
Harding, A.H.3
Halsall, D.J.4
O'Rahilly, S.5
Chatterjee, V.K.6
Wareham, N.J.7
-
48
-
-
22844440105
-
Leptin receptor gene variation predicts weight change in subjects with impaired glucose tolerance
-
Zacharova J, Chiasson JL, Laakso M (2005) Leptin receptor gene variation predicts weight change in subjects with impaired glucose tolerance. Obes Res 13:501-506
-
(2005)
Obes Res
, vol.13
, pp. 501-506
-
-
Zacharova, J.1
Chiasson, J.L.2
Laakso, M.3
-
49
-
-
24344504484
-
Obese subjects carrying the 11482G>A polymorphism at the perilipin locus are resistant to weight loss after dietary energy restriction
-
Corella D, Qi L, Sorli JV, Godoy D, Portoles O, Coltell O, Greenberg AS, Ordovas JM (2005) Obese subjects carrying the 11482G>A polymorphism at the perilipin locus are resistant to weight loss after dietary energy restriction. J Clin Endocrinol Metab 90:5121-5126
-
(2005)
J Clin Endocrinol Metab
, vol.90
, pp. 5121-5126
-
-
Corella, D.1
Qi, L.2
Sorli, J.V.3
Godoy, D.4
Portoles, O.5
Coltell, O.6
Greenberg, A.S.7
Ordovas, J.M.8
-
50
-
-
0030731084
-
Effects of Trp64Arg mutation in the beta 3-adrenergic receptor gene on weight loss, body fat distribution, glycemic control, and insulin resistance in obese type 2 diabetic patients
-
Sakane N, Yoshida T, Umekawa T, Kogure A, Takakura Y, Kondo M (1997) Effects of Trp64Arg mutation in the beta 3-adrenergic receptor gene on weight loss, body fat distribution, glycemic control, and insulin resistance in obese type 2 diabetic patients. Diabetes Care 20:1887-1890
-
(1997)
Diabetes Care
, vol.20
, pp. 1887-1890
-
-
Sakane, N.1
Yoshida, T.2
Umekawa, T.3
Kogure, A.4
Takakura, Y.5
Kondo, M.6
-
51
-
-
1542270110
-
Additive effect of the mutations in the beta3-adrenoceptor gene and UCP3 gene promoter on body fat distribution and glycemic control after weight reduction in overweight subjects with CAD or metabolic syndrome
-
Kim OY, Cho EY, Park HY, Jang Y, Lee JH (2004) Additive effect of the mutations in the beta3-adrenoceptor gene and UCP3 gene promoter on body fat distribution and glycemic control after weight reduction in overweight subjects with CAD or metabolic syndrome. Int J Obes Relat Metab Disord 28:434-441
-
(2004)
Int J Obes Relat Metab Disord
, vol.28
, pp. 434-441
-
-
Kim, O.Y.1
Cho, E.Y.2
Park, H.Y.3
Jang, Y.4
Lee, J.H.5
-
52
-
-
0038353486
-
Promoter polymorphisms of the TNF-alpha (G-308A) and IL-6 (C-174G) genes predict the conversion from impaired glucose tolerance to type 2 diabetes: The Finnish Diabetes Prevention Study
-
Kubaszek A, Pihlajamaki J, Komarovski V, Lindi V, Lindstrom J, Eriksson J, Valle TT, Hamalainen H, Ilanne-Parikka P, Keinanen-Kiukaanniemi S, Tuomilehto J, Uusitupa M, Laakso M (2003) Promoter polymorphisms of the TNF-alpha (G-308A) and IL-6 (C-174G) genes predict the conversion from impaired glucose tolerance to type 2 diabetes: the Finnish Diabetes Prevention Study. Diabetes 52:1872-1876
-
(2003)
Diabetes
, vol.52
, pp. 1872-1876
-
-
Kubaszek, A.1
Pihlajamaki, J.2
Komarovski, V.3
Lindi, V.4
Lindstrom, J.5
Eriksson, J.6
Valle, T.T.7
Hamalainen, H.8
Ilanne-Parikka, P.9
Keinanen-Kiukaanniemi, S.10
Tuomilehto, J.11
Uusitupa, M.12
Laakso, M.13
-
53
-
-
4844229786
-
Common variants in beta2-and beta3-adrenergic receptor genes and uncoupling protein 1 as predictors of the risk for type 2 diabetes and body weight changes. The Finnish Diabetes Prevention Study
-
Salopuro T, Lindstrom J, Eriksson JG, Valle TT, Hamalainen H, Ilanne-Parikka P, Keinanen-Kiukaanniemi S, Tuomilehto J, Laakso M, Uusitupa M (2004) Common variants in beta2-and beta3-adrenergic receptor genes and uncoupling protein 1 as predictors of the risk for type 2 diabetes and body weight changes. The Finnish Diabetes Prevention Study. Clin Genet 66:365-367
-
(2004)
Clin Genet
, vol.66
, pp. 365-367
-
-
Salopuro, T.1
Lindstrom, J.2
Eriksson, J.G.3
Valle, T.T.4
Hamalainen, H.5
Ilanne-Parikka, P.6
Keinanen-Kiukaanniemi, S.7
Tuomilehto, J.8
Laakso, M.9
Uusitupa, M.10
-
54
-
-
10344246071
-
Polymorphisms of the SUR1 (ABCC8) and Kir6.2 (KCNJ11) genes predict the conversion from impaired glucose tolerance to type 2 diabetes. The Finnish Diabetes Prevention Study
-
Laukkanen O, Pihlajamaki J, Lindstrom J, Eriksson J, Valle TT, Hamalainen H, Ilanne-Parikka P, Keinanen-Kiukaanniemi S, Tuomilehto J, Uusitupa M, Laakso M (2004) Polymorphisms of the SUR1 (ABCC8) and Kir6.2 (KCNJ11) genes predict the conversion from impaired glucose tolerance to type 2 diabetes. The Finnish Diabetes Prevention Study. J Clin Endocrinol Metab 89:6286-6290
-
(2004)
J Clin Endocrinol Metab
, vol.89
, pp. 6286-6290
-
-
Laukkanen, O.1
Pihlajamaki, J.2
Lindstrom, J.3
Eriksson, J.4
Valle, T.T.5
Hamalainen, H.6
Ilanne-Parikka, P.7
Keinanen-Kiukaanniemi, S.8
Tuomilehto, J.9
Uusitupa, M.10
Laakso, M.11
-
55
-
-
2942538530
-
Common polymorphisms in the genes regulating the early insulin signalling pathway: Effects on weight change and the conversion from impaired glucose tolerance to Type 2 diabetes. The Finnish Diabetes Prevention Study
-
Laukkanen O, Pihlajamaki J, Lindstrom J, Eriksson J, Valle TT, Hamalainen H, Ilanne-Parikka P, Keinanen-Kiukaanniemi S, Tuomilehto J, Uusitupa M, Laakso M (2004) Common polymorphisms in the genes regulating the early insulin signalling pathway: effects on weight change and the conversion from impaired glucose tolerance to Type 2 diabetes. The Finnish Diabetes Prevention Study. Diabetologia 47:871-877
-
(2004)
Diabetologia
, vol.47
, pp. 871-877
-
-
Laukkanen, O.1
Pihlajamaki, J.2
Lindstrom, J.3
Eriksson, J.4
Valle, T.T.5
Hamalainen, H.6
Ilanne-Parikka, P.7
Keinanen-Kiukaanniemi, S.8
Tuomilehto, J.9
Uusitupa, M.10
Laakso, M.11
-
56
-
-
2442600044
-
The G-250A promoter polymorphism of the hepatic lipase gene predicts the conversion from impaired glucose tolerance to type 2 diabetes mellitus: The Finnish Diabetes Prevention Study
-
Todorova B, Kubaszek A, Pihlajamaki J, Lindstrom J, Eriksson J, Valle TT, Hamalainen H, Ilanne-Parikka P, Keinanen-Kiukaanniemi S, Tuomilehto J, Uusitupa M, Laakso M (2004) The G-250A promoter polymorphism of the hepatic lipase gene predicts the conversion from impaired glucose tolerance to type 2 diabetes mellitus: the Finnish Diabetes Prevention Study. J Clin Endocrinol Metab 89:2019-2023
-
(2004)
J Clin Endocrinol Metab
, vol.89
, pp. 2019-2023
-
-
Todorova, B.1
Kubaszek, A.2
Pihlajamaki, J.3
Lindstrom, J.4
Eriksson, J.5
Valle, T.T.6
Hamalainen, H.7
Ilanne-Parikka, P.8
Keinanen-Kiukaanniemi, S.9
Tuomilehto, J.10
Uusitupa, M.11
Laakso, M.12
-
57
-
-
30544443607
-
Genetic variation in leptin receptor gene is associated with type 2 diabetes and body weight: The Finnish Diabetes Prevention Study
-
Lond
-
Salopuro T, Pulkkinen L, Lindstrom J, Eriksson JG, Valle TT, Hamalainen H, Ilanne-Parikka P, Keinanen-Kiukaanniemi S, Tuomilehto J, Laakso M, Uusitupa M (2005) Genetic variation in leptin receptor gene is associated with type 2 diabetes and body weight: the Finnish Diabetes Prevention Study. Int J Obes (Lond) 29:1245-1251
-
(2005)
Int J Obes
, vol.29
, pp. 1245-1251
-
-
Salopuro, T.1
Pulkkinen, L.2
Lindstrom, J.3
Eriksson, J.G.4
Valle, T.T.5
Hamalainen, H.6
Ilanne-Parikka, P.7
Keinanen-Kiukaanniemi, S.8
Tuomilehto, J.9
Laakso, M.10
Uusitupa, M.11
-
58
-
-
21344437030
-
Polymorphisms in the SLC2A2 (GLUT2) gene are associated with the conversion from impaired glucose tolerance to type 2 diabetes: The Finnish Diabetes Prevention Study
-
Laukkanen O, Lindstrom J, Eriksson J, Valle TT, Hamalainen H, Ilanne-Parikka P, Keinanen-Kiukaanniemi S, Tuomilehto J, Uusitupa M, Laakso M (2005) Polymorphisms in the SLC2A2 (GLUT2) gene are associated with the conversion from impaired glucose tolerance to type 2 diabetes: the Finnish Diabetes Prevention Study. Diabetes 54:2256-2260
-
(2005)
Diabetes
, vol.54
, pp. 2256-2260
-
-
Laukkanen, O.1
Lindstrom, J.2
Eriksson, J.3
Valle, T.T.4
Hamalainen, H.5
Ilanne-Parikka, P.6
Keinanen-Kiukaanniemi, S.7
Tuomilehto, J.8
Uusitupa, M.9
Laakso, M.10
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