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1
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0028833556
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Macromolecular drug carrier systems in cancer chemotherapy: Macromolecular prodrugs
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Y. Takakura and M. Hashida. Macromolecular drug carrier systems in cancer chemotherapy: Macromolecular prodrugs. Crit. Rev. Oncol. Hematol. 18:207-231 (1995).
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Crit. Rev. Oncol. Hematol.
, vol.18
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Takakura, Y.1
Hashida, M.2
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2
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0002079949
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Disposition and tumour localization of mitomycin C-dextran conjugates in mice
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Y. Takakura, A. Takagi, M. Hashida and H. Sezaki. Disposition and tumour localization of mitomycin C-dextran conjugates in mice. Pharm. Res. 4:293-300 (1987).
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Pharm. Res.
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Takakura, Y.1
Takagi, A.2
Hashida, M.3
Sezaki, H.4
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3
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-
0027982550
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Pharmacokinetics in design of polymeric drug delivery systems
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M. Hashida and Y. Takakura. Pharmacokinetics in design of polymeric drug delivery systems. J. Controlled Release 31:163-171 (1994).
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(1994)
J. Controlled Release
, vol.31
, pp. 163-171
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Hashida, M.1
Takakura, Y.2
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4
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0028967474
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Design for cell-specific targeting of proteins utilizing sugar-recognition mechanism: Effect of molecular weight of proteins on targeting efficiency
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M. Nishikawa, H. Hirabayashi, Y. Takakura and M. Hashida. Design for cell-specific targeting of proteins utilizing sugar-recognition mechanism: Effect of molecular weight of proteins on targeting efficiency. Pharm. Res. 12:209-214 (1995).
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(1995)
Pharm. Res.
, vol.12
, pp. 209-214
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Nishikawa, M.1
Hirabayashi, H.2
Takakura, Y.3
Hashida, M.4
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5
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0029014068
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Galactosylated proteins are recognized by the liver according to the surface density of galactose moieties
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M. Nishikawa, C. Miyazaki, F. Yamashita, Y. Takakura and M. Hashida. Galactosylated proteins are recognized by the liver according to the surface density of galactose moieties. Am. J. Physiol. 268:G849-G856 (1995).
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(1995)
Am. J. Physiol.
, vol.268
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Nishikawa, M.1
Miyazaki, C.2
Yamashita, F.3
Takakura, Y.4
Hashida, M.5
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6
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0027185699
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Synthesis and pharmacokinetics of a new liver-specific carrier, glycosylated carboxymethyl-dextran, and its application to drug targeting
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M. Nishikawa, A. Kamijo, T. Fujita, Y. Takakura, H. Sezaki and M. Hashida. Synthesis and pharmacokinetics of a new liver-specific carrier, glycosylated carboxymethyl-dextran, and its application to drug targeting. Pharm. Res. 10:1253-1261 (1993).
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(1993)
Pharm. Res.
, vol.10
, pp. 1253-1261
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Nishikawa, M.1
Kamijo, A.2
Fujita, T.3
Takakura, Y.4
Sezaki, H.5
Hashida, M.6
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7
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0026980122
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Targeted delivery of human recombinant superoxide dismutase by chemical modification with mono- and poly-saccharide derivatives
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T. Fujita, M. Nishikawa, C. Tamaki, Y. Takakura, M. Hashida and H. Sezaki. Targeted delivery of human recombinant superoxide dismutase by chemical modification with mono- and poly-saccharide derivatives. J. Pharmacol. Exp. Ther. 263:971-978 (1992).
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(1992)
J. Pharmacol. Exp. Ther.
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, pp. 971-978
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Fujita, T.1
Nishikawa, M.2
Tamaki, C.3
Takakura, Y.4
Hashida, M.5
Sezaki, H.6
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8
-
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0027102397
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Therapeutic effects of superoxide dismutase derivatives modified with mono- or polysaccharides on hepatic injury induced by ischemia/reperfusion
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T. Fujita, M. Nishikawa, C. Tamaki, Y. Takakura, M. Hashida and H. Sezaki. Therapeutic effects of superoxide dismutase derivatives modified with mono- or polysaccharides on hepatic injury induced by ischemia/reperfusion. Biochem. Biophys. Res. Commun. 189:191-196 (1992).
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(1992)
Biochem. Biophys. Res. Commun.
, vol.189
, pp. 191-196
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Fujita, T.1
Nishikawa, M.2
Tamaki, C.3
Takakura, Y.4
Hashida, M.5
Sezaki, H.6
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9
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0021739518
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Physicochemical and antitumor characteristics of some polyamino acid prodrugs of mitomycin C
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C. F. Roos, S. Matsumoto, Y. Takakura, M. Hashida and H. Sezaki. Physicochemical and antitumor characteristics of some polyamino acid prodrugs of mitomycin C. Int. J. Pharm. 22:75-87 (1984).
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(1984)
Int. J. Pharm.
, vol.22
, pp. 75-87
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Roos, C.F.1
Matsumoto, S.2
Takakura, Y.3
Hashida, M.4
Sezaki, H.5
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10
-
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0021161941
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Antitumor agent poly (amino acid) conjugates as a drug carrier in cancer chemotherapy
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Y. Morimoto, K. Sugibayashi, S. Sugihara, K. Hosoya, S. Nozaki and Y. Ogawa. Antitumor agent poly (amino acid) conjugates as a drug carrier in cancer chemotherapy. J. Pharmacobio-Dyn. 7:688-698 (1984).
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J. Pharmacobio-Dyn.
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Morimoto, Y.1
Sugibayashi, K.2
Sugihara, S.3
Hosoya, K.4
Nozaki, S.5
Ogawa, Y.6
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11
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0025223382
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Effect of electric charge on the hepatic uptake of macromolecules in the rat liver
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K. Nishida, C. Tonegawa, S. Nakane, Y. Takakura, M. Hashida and H. Sezaki. Effect of electric charge on the hepatic uptake of macromolecules in the rat liver. Int. J. Pharm. 65:7-17 (1990).
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(1990)
Int. J. Pharm.
, vol.65
, pp. 7-17
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Nishida, K.1
Tonegawa, C.2
Nakane, S.3
Takakura, Y.4
Hashida, M.5
Sezaki, H.6
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12
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0027368237
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111-DTPA-labeled receptor targeted proteins
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111-DTPA-labeled receptor targeted proteins. J. Nucl. Med. 34:1728-1738 (1993).
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J. Nucl. Med.
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Duncan, J.R.1
Welch, M.J.2
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14
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0028351444
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Pharmacokinetics of succinylated proteins and dextran sulfate in mice: Implication for hepatic targeting of protein drugs by direct succinylation via scavenger receptors
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Y. Takakura, T. Fujita, H. Furitsu, M. Nishikawa, H. Sezaki and M. Hashida. Pharmacokinetics of succinylated proteins and dextran sulfate in mice: Implication for hepatic targeting of protein drugs by direct succinylation via scavenger receptors. Int. J. Pharm. 105:19-29 (1994).
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Int. J. Pharm.
, vol.105
, pp. 19-29
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Takakura, Y.1
Fujita, T.2
Furitsu, H.3
Nishikawa, M.4
Sezaki, H.5
Hashida, M.6
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16
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0025210490
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A new radiochemical method to determine the stability constants of metal chelates attached to a protein
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K. M. Subramanian and W. Wolf. A new radiochemical method to determine the stability constants of metal chelates attached to a protein. J. Nucl. Med 31:480-488 (1990).
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J. Nucl. Med
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Subramanian, K.M.1
Wolf, W.2
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17
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0017976656
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Glomerular permselectivity: Barrier function based on discrimination of molecular size and charge
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B. M. Brenner, T. H. Hostetter and H. D. Humes. Glomerular permselectivity: Barrier function based on discrimination of molecular size and charge. Am. J. Physiol. 234:F455-F460 (1978).
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Am. J. Physiol.
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Brenner, B.M.1
Hostetter, T.H.2
Humes, H.D.3
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18
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0017092940
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Attachment of thioglycosides to proteins: Enhancement of liver membrane binding
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M. J. Krantz, N. A. Holtzman, C. P. Stowell and Y. C. Lee. Attachment of thioglycosides to proteins: Enhancement of liver membrane binding. Biochemistry 15:3963-3968 (1976).
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Biochemistry
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Krantz, M.J.1
Holtzman, N.A.2
Stowell, C.P.3
Lee, Y.C.4
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19
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0001387190
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Some macromolecular properties of poly (α-L-glutamic acid) random coils
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R. B. Hawkins and A. Holtzer. Some macromolecular properties of poly (α-L-glutamic acid) random coils. Macromolecules 5:294-301 (1972).
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Macromolecules
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Hawkins, R.B.1
Holtzer, A.2
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