Bcl-2 upregulation and neuroprotection in guinea pig brain following chronic simvastatin treatment

Neurobiology of Disease

Volumn 25, Issue 2, 2007, Pages 438-445

  Franke, Cornelia ^a   Nöldner, Michael ^b   Abdel Kader, Reham ^a   Johnson Anuna, Leslie N ^c   Gibson Wood, W ^c   Müller, Walter E ^a   Eckert, Gunter P ^a  

^a GOETHE UNIVERSITY   (Germany)

^b DR WILLMAR SCHWABE GMBH AND CO KG   (Germany)

^c UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

Author keywords

Bax; Bcl 2; Guinea pigs; HA 14 1; Neuroprotection; Simvastatin; SNP

Indexed keywords

2 AMINO 6 BROMO 4 (1 CYANO 2 ETHOXY 2 OXOETHYL) 4H CHROMENE 3 CARBOXYLIC ACID ETHYL ESTER; CASPASE; CHOLESTEROL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; NITRIC OXIDE DONOR; NITROPRUSSIDE SODIUM; PROTEIN BAX; PROTEIN BCL 2; SIMVASTATIN; STATIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL ISOLATION; CHRONIC DRUG ADMINISTRATION; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DOWN REGULATION; DRUG ACTIVITY; DRUG MECHANISM; ENZYME ACTIVATION; GENE OVEREXPRESSION; GUINEA PIG; IN VIVO STUDY; MALE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION;

ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BENZOPYRANS; BRAIN; CASPASES; CELLS, CULTURED; DRUG ADMINISTRATION SCHEDULE; ENZYME INHIBITORS; GUINEA PIGS; MALE; MITOCHONDRIA; NEURONS; NEUROPROTECTIVE AGENTS; NITRIC OXIDE DONORS; NITRILES; PROTO-ONCOGENE PROTEINS C-BCL-2; SIMVASTATIN; UP-REGULATION;

EID: 33846439745     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2006.10.004     Document Type: Article

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