메뉴 건너뛰기




Volumn 45, Issue 1, 2007, Pages 22-30

Intrahepatic delivery of α-galactosylceramide-pulsed dendritic cells suppresses liver tumor

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA GALACTOSYLCERAMIDE; GAMMA INTERFERON; PROTEIN P53;

EID: 33846413504     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.21447     Document Type: Article
Times cited : (39)

References (41)
  • 1
    • 0025735629 scopus 로고
    • The dendritic cell system and its role in immunogenicity
    • Steinman RM. The dendritic cell system and its role in immunogenicity. Annu Rev Immunol 1991;9:271-296.
    • (1991) Annu Rev Immunol , vol.9 , pp. 271-296
    • Steinman, R.M.1
  • 2
    • 0030781916 scopus 로고    scopus 로고
    • Dendritic cells: Unique leukocyte populations which control the primary immune response
    • Hart DN. Dendritic cells: unique leukocyte populations which control the primary immune response. Blood 1997;90:3245-3287.
    • (1997) Blood , vol.90 , pp. 3245-3287
    • Hart, D.N.1
  • 3
    • 4944223122 scopus 로고    scopus 로고
    • Manipulating dendritic cell biology for the active immunotherapy of cancer
    • O'Neill DW, Adams S, Bhardwaj N. Manipulating dendritic cell biology for the active immunotherapy of cancer. Blood 2004;104:2235-2246.
    • (2004) Blood , vol.104 , pp. 2235-2246
    • O'Neill, D.W.1    Adams, S.2    Bhardwaj, N.3
  • 4
    • 0032903599 scopus 로고    scopus 로고
    • Dendritic cells directly trigger NK cell functions: Cross-talk relevant in innate anti-tumor immune responses in vivo
    • Fernandez NC, Lozier A, Flament C, Ricciardi-Castagnoli P, Beller D, Suter M, et al. Dendritic cells directly trigger NK cell functions: cross-talk relevant in innate anti-tumor immune responses in vivo. Nat Med 1999; 5:405-411.
    • (1999) Nat Med , vol.5 , pp. 405-411
    • Fernandez, N.C.1    Lozier, A.2    Flament, C.3    Ricciardi-Castagnoli, P.4    Beller, D.5    Suter, M.6
  • 6
    • 0037017387 scopus 로고    scopus 로고
    • Human dendritic cells activate resting NK cells and are recognized via the NKp30 receptor by activated NK cells
    • Ferlazzo G, Tsang ML, Moretta L, Melioli G, Steinman RM, Munz C. Human dendritic cells activate resting NK cells and are recognized via the NKp30 receptor by activated NK cells. J Exp Med 2002;195:343-351.
    • (2002) J Exp Med , vol.195 , pp. 343-351
    • Ferlazzo, G.1    Tsang, M.L.2    Moretta, L.3    Melioli, G.4    Steinman, R.M.5    Munz, C.6
  • 7
    • 0037017379 scopus 로고    scopus 로고
    • Contact-dependent stimulation and inhibition of dendritic cells by natural killer cells
    • Piccioli D, Sbrana S, Melandri E, Valiante NM. Contact-dependent stimulation and inhibition of dendritic cells by natural killer cells. J Exp Med 2002;195:335-341.
    • (2002) J Exp Med , vol.195 , pp. 335-341
    • Piccioli, D.1    Sbrana, S.2    Melandri, E.3    Valiante, N.M.4
  • 8
    • 0037389719 scopus 로고    scopus 로고
    • Overexpression of interleukin-12 enables dendritic cells to activate NK cells and confer systemic antitumor immunity
    • Miller G, Lahrs S, Dematteo RP. Overexpression of interleukin-12 enables dendritic cells to activate NK cells and confer systemic antitumor immunity. FASEB J 2003;17:728-730.
    • (2003) FASEB J , vol.17 , pp. 728-730
    • Miller, G.1    Lahrs, S.2    Dematteo, R.P.3
  • 9
    • 0030696696 scopus 로고    scopus 로고
    • CD1d-restricted and TCR-mediated activation of Vα14NKT cells by glycosylceramides
    • Kawano T, Cui J, Koezuka Y, Toura I, Kaneko Y, Motoki H, et al. CD1d-restricted and TCR-mediated activation of Vα14NKT cells by glycosylceramides. Science 1997;278:1626-1629.
    • (1997) Science , vol.278 , pp. 1626-1629
    • Kawano, T.1    Cui, J.2    Koezuka, Y.3    Toura, I.4    Kaneko, Y.5    Motoki, H.6
  • 10
    • 13144249230 scopus 로고    scopus 로고
    • Natural killer-like nonspecific tumor cell lysis mediated by specific ligand-activated Vα14NKT cells
    • Kawano T, Cui J, Koezuka Y, Toura I, Kaneko K, Sato H, et al. Natural killer-like nonspecific tumor cell lysis mediated by specific ligand-activated Vα14NKT cells. Proc Natl Acad Sci U S A 1998;95:5690-5693.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 5690-5693
    • Kawano, T.1    Cui, J.2    Koezuka, Y.3    Toura, I.4    Kaneko, K.5    Sato, H.6
  • 11
    • 0033526066 scopus 로고    scopus 로고
    • The natural killer T (NKT) cell ligand α-galactosylceramide demonstrates its immunopoteniating effect by inducing interleukin (IL)-12 production by dendritic cells and IL-12 receptor expression on NKT cells
    • Kitamura H, Iwakabe K, Yahata T, Nishimura S, Ohta A, Ohmi S, et al. The natural killer T (NKT) cell ligand α-galactosylceramide demonstrates its immunopoteniating effect by inducing interleukin (IL)-12 production by dendritic cells and IL-12 receptor expression on NKT cells. J Exp Med 1999;189:1121-1128.
    • (1999) J Exp Med , vol.189 , pp. 1121-1128
    • Kitamura, H.1    Iwakabe, K.2    Yahata, T.3    Nishimura, S.4    Ohta, A.5    Ohmi, S.6
  • 12
    • 0034113629 scopus 로고    scopus 로고
    • Innate and adaptive lymphoid cells in human liver
    • Doherty DG, O'Farrelly C. Innate and adaptive lymphoid cells in human liver. Immunol Rev 2000;174:5-20.
    • (2000) Immunol Rev , vol.174 , pp. 5-20
    • Doherty, D.G.1    O'Farrelly, C.2
  • 13
    • 0035165909 scopus 로고    scopus 로고
    • Immunology of the healthy liver: Old questions and new insights
    • Mehal WZ, Azzaroli F, Crispe IN. Immunology of the healthy liver: Old questions and new insights. Gastroenterology 2001;120:250-260.
    • (2001) Gastroenterology , vol.120 , pp. 250-260
    • Mehal, W.Z.1    Azzaroli, F.2    Crispe, I.N.3
  • 14
    • 0036378352 scopus 로고    scopus 로고
    • Treatment of non-resectable hepatocellular carcinoma with autologous tumor-pulsed dendritic cells
    • Ladhams A, Schmidt C, Sing G, Butterworth L, Fielding G, Tesar P, et al. Treatment of non-resectable hepatocellular carcinoma with autologous tumor-pulsed dendritic cells. J Gastroenterol Hepatol 2002;17:889-896.
    • (2002) J Gastroenterol Hepatol , vol.17 , pp. 889-896
    • Ladhams, A.1    Schmidt, C.2    Sing, G.3    Butterworth, L.4    Fielding, G.5    Tesar, P.6
  • 15
    • 0037384518 scopus 로고    scopus 로고
    • A phase I study of autologous dendritic cell-based immunotherapy for patients with unresectable primary liver cancer
    • Iwashita Y, Tahara K, Goto S, Sasaki A, Kai S, Seike M, et al. A phase I study of autologous dendritic cell-based immunotherapy for patients with unresectable primary liver cancer. Cancer Immunol Immunother 2003;52: 155-161.
    • (2003) Cancer Immunol Immunother , vol.52 , pp. 155-161
    • Iwashita, Y.1    Tahara, K.2    Goto, S.3    Sasaki, A.4    Kai, S.5    Seike, M.6
  • 16
    • 14744275172 scopus 로고    scopus 로고
    • Combination of conformal radiotherapy and intratumoral injection of adoptive dendritic cell immunotherapy in refractory hepatoma
    • Chi KH, Liu SJ, Li CP, Kuo HP, Wang YS, Chao Y, et al. Combination of conformal radiotherapy and intratumoral injection of adoptive dendritic cell immunotherapy in refractory hepatoma. J Immunother 2005;28:129-135.
    • (2005) J Immunother , vol.28 , pp. 129-135
    • Chi, K.H.1    Liu, S.J.2    Li, C.P.3    Kuo, H.P.4    Wang, Y.S.5    Chao, Y.6
  • 17
    • 24144433435 scopus 로고    scopus 로고
    • Vaccination of advanced hepatocellular carcinoma patients with tumor lysate-pulsed dendrite cells: A clinical trial
    • Lee WC, Wang HC, Hung CF, Huang PF, Lia CR, Chen MF. Vaccination of advanced hepatocellular carcinoma patients with tumor lysate-pulsed dendrite cells: a clinical trial. J Immunother 2005;28:496-504.
    • (2005) J Immunother , vol.28 , pp. 496-504
    • Lee, W.C.1    Wang, H.C.2    Hung, C.F.3    Huang, P.F.4    Lia, C.R.5    Chen, M.F.6
  • 18
    • 0036735859 scopus 로고    scopus 로고
    • Prolonged IFN-γ-producing NKT response induced with alpha-galactosylceramide-loaded DCs
    • Fujii S, Shimizu K, Kronenberg M, Steinman RM. Prolonged IFN-γ-producing NKT response induced with alpha-galactosylceramide-loaded DCs. Nat Immunol 2002;3:867-874.
    • (2002) Nat Immunol , vol.3 , pp. 867-874
    • Fujii, S.1    Shimizu, K.2    Kronenberg, M.3    Steinman, R.M.4
  • 20
    • 0038206873 scopus 로고    scopus 로고
    • CD1d-mediated stimulation of natural killer T cells selectively activates hepatic natural killer cells to eliminate experimentally disseminated hepatoma cells in murine liver
    • Miyagi T, Takehara T, Tatsumi T, Kanto T, Suzuki T, Jinushi M, et al. CD1d-mediated stimulation of natural killer T cells selectively activates hepatic natural killer cells to eliminate experimentally disseminated hepatoma cells in murine liver. Int J Cancer 2003;106:81-89.
    • (2003) Int J Cancer , vol.106 , pp. 81-89
    • Miyagi, T.1    Takehara, T.2    Tatsumi, T.3    Kanto, T.4    Suzuki, T.5    Jinushi, M.6
  • 21
    • 0032521202 scopus 로고    scopus 로고
    • Treatment of hepatic metastasis of the colon26 adenocacinoma with an α-galactosylceramide, KRN7000
    • Nakagawa R, Motoki K, Ueno H, Iijima R, Nakamura H, Kobayashi E, et al. Treatment of hepatic metastasis of the colon26 adenocacinoma with an α-galactosylceramide, KRN7000. Cancer Res 1998;58:1202-1207.
    • (1998) Cancer Res , vol.58 , pp. 1202-1207
    • Nakagawa, R.1    Motoki, K.2    Ueno, H.3    Iijima, R.4    Nakamura, H.5    Kobayashi, E.6
  • 22
    • 0033197917 scopus 로고    scopus 로고
    • Inhibition of experimental tumor metastasis by dendritic cells pulsed with α-galactosylceramide
    • Toura I, Kawano T, Akutsu Y, Nakayama T, Ochiai T, Taniguchi M. Inhibition of experimental tumor metastasis by dendritic cells pulsed with α-galactosylceramide. J Immunol 1999;163:2387-2391.
    • (1999) J Immunol , vol.163 , pp. 2387-2391
    • Toura, I.1    Kawano, T.2    Akutsu, Y.3    Nakayama, T.4    Ochiai, T.5    Taniguchi, M.6
  • 23
    • 0942276861 scopus 로고    scopus 로고
    • Nieda M, Okai M, Tazbirkova A, Lin H, Yamaura A, Ide K, et al. Therapeutic activation of Vα24+Vβ11+NKT cells in human subjects results in highly coordinates secondary activation of acquired and innate immunity. Blood 2004;103:383-389.
    • Nieda M, Okai M, Tazbirkova A, Lin H, Yamaura A, Ide K, et al. Therapeutic activation of Vα24+Vβ11+NKT cells in human subjects results in highly coordinates secondary activation of acquired and innate immunity. Blood 2004;103:383-389.
  • 24
    • 0036896332 scopus 로고    scopus 로고
    • A phase I study of the natural killer T-cell ligand α-galactosylceramide (KRN7000) in patients with solid tumors
    • Giaccone G, Punt CJ, Ando Y, Ruijter R, Nishi N, Peters M, et al. A phase I study of the natural killer T-cell ligand α-galactosylceramide (KRN7000) in patients with solid tumors. Clin Cancer Res 2002;8:3702-3709.
    • (2002) Clin Cancer Res , vol.8 , pp. 3702-3709
    • Giaccone, G.1    Punt, C.J.2    Ando, Y.3    Ruijter, R.4    Nishi, N.5    Peters, M.6
  • 25
    • 20144388064 scopus 로고    scopus 로고
    • A phase I study of α-galactosylceramide (KRN7000)-pulsed dendritic cells in patients with advanced and recurrent non-small cell lung cancer
    • Ishikawa A, Motohashi S, Ishikawa E, Fuchida H, Higashino K, Otsuji M, et al. A phase I study of α-galactosylceramide (KRN7000)-pulsed dendritic cells in patients with advanced and recurrent non-small cell lung cancer. Clin Cancer Res 2005;11:1910-1917.
    • (2005) Clin Cancer Res , vol.11 , pp. 1910-1917
    • Ishikawa, A.1    Motohashi, S.2    Ishikawa, E.3    Fuchida, H.4    Higashino, K.5    Otsuji, M.6
  • 26
    • 20844451391 scopus 로고    scopus 로고
    • Sustained expansion of NKT cells and antigen-specific T cells after injection of α-galactosyl-ceramide loaded mature dendritic cells in cancer patients
    • Chang DH, Osman K, Connolly J, Kukreja A, Krasovsky J, Pack M, et al. Sustained expansion of NKT cells and antigen-specific T cells after injection of α-galactosyl-ceramide loaded mature dendritic cells in cancer patients. J Exp Med 2005;201:1503-1517.
    • (2005) J Exp Med , vol.201 , pp. 1503-1517
    • Chang, D.H.1    Osman, K.2    Connolly, J.3    Kukreja, A.4    Krasovsky, J.5    Pack, M.6
  • 27
    • 0034777510 scopus 로고    scopus 로고
    • Different requirements for α-galactosylceramide and recombinant interleukin-12 antitumor activity in the treatment of C-26 colon carcinoma hepatic metastases
    • Chiodoni C, Stoppacciaro A, Sangaletti S, Gri G, Cappetti B, Koezuka Y, et al. Different requirements for α-galactosylceramide and recombinant interleukin-12 antitumor activity in the treatment of C-26 colon carcinoma hepatic metastases. Eur J Immunol 2001;31:3101-3110.
    • (2001) Eur J Immunol , vol.31 , pp. 3101-3110
    • Chiodoni, C.1    Stoppacciaro, A.2    Sangaletti, S.3    Gri, G.4    Cappetti, B.5    Koezuka, Y.6
  • 29
    • 0141919560 scopus 로고    scopus 로고
    • Intratumoral delivery of dendritic cells engineered to secrete both interleukin(IL)-12 and IL-18 effectively treats local and distant disease in association with broadly reactive Tc1-type immunity
    • Tatsumi T, Huang J, Gooding WE, Gambotto A, Robbins PD, Vujanovic NL, et al. Intratumoral delivery of dendritic cells engineered to secrete both interleukin(IL)-12 and IL-18 effectively treats local and distant disease in association with broadly reactive Tc1-type immunity. Cancer Res 2003; 63:6378-6386.
    • (2003) Cancer Res , vol.63 , pp. 6378-6386
    • Tatsumi, T.1    Huang, J.2    Gooding, W.E.3    Gambotto, A.4    Robbins, P.D.5    Vujanovic, N.L.6
  • 30
    • 0030584839 scopus 로고    scopus 로고
    • Induction of antitumor immunity using bone marrow-generated dendritic cells
    • Porgador A, Snyder D, Gilboa E. Induction of antitumor immunity using bone marrow-generated dendritic cells. J Immunol 1996;156: 2918-2926.
    • (1996) J Immunol , vol.156 , pp. 2918-2926
    • Porgador, A.1    Snyder, D.2    Gilboa, E.3
  • 31
    • 0028793675 scopus 로고
    • Bone marrow-derived dendritic cells pulsed with synthetic tumor peptide elicits protective and therapeutic antitumor immunity
    • Mayordomo JI, Zorina T, Storkus WJ, Zitvogel L, Celluzzi C, Falo LD Jr, et al. Bone marrow-derived dendritic cells pulsed with synthetic tumor peptide elicits protective and therapeutic antitumor immunity. Nat Med 1995;12:1297-1302.
    • (1995) Nat Med , vol.12 , pp. 1297-1302
    • Mayordomo, J.I.1    Zorina, T.2    Storkus, W.J.3    Zitvogel, L.4    Celluzzi, C.5    Falo Jr, L.D.6
  • 32
    • 0030026776 scopus 로고    scopus 로고
    • Vaccination of patients with B-cell lymphoma using autologous antigen-pulsed dendritic cells
    • Hsu FJ, Benike C, Fagnoni F, Liles TM, Czerwinski D, Taidi B, et al. Vaccination of patients with B-cell lymphoma using autologous antigen-pulsed dendritic cells. Nat Med 1996;2:52-58.
    • (1996) Nat Med , vol.2 , pp. 52-58
    • Hsu, F.J.1    Benike, C.2    Fagnoni, F.3    Liles, T.M.4    Czerwinski, D.5    Taidi, B.6
  • 33
    • 0031941423 scopus 로고    scopus 로고
    • Vaccination of melanoma patients with peptide- or tumor lysate-pulsed dendritic cells
    • Nestle FO, Alijagic S, Gilliet M, Sun Y, Grabbe S, Dummer R, et al. Vaccination of melanoma patients with peptide- or tumor lysate-pulsed dendritic cells. Nat Med 1998;4:328-332.
    • (1998) Nat Med , vol.4 , pp. 328-332
    • Nestle, F.O.1    Alijagic, S.2    Gilliet, M.3    Sun, Y.4    Grabbe, S.5    Dummer, R.6
  • 35
    • 1642444661 scopus 로고    scopus 로고
    • NK cell compartments and their activation by dendritic cells
    • Ferlazzo G, Munz C. NK cell compartments and their activation by dendritic cells. J Immunol 2004;172:1333-1339.
    • (2004) J Immunol , vol.172 , pp. 1333-1339
    • Ferlazzo, G.1    Munz, C.2
  • 36
    • 0030058647 scopus 로고    scopus 로고
    • Therapy of murine tumors with tumor peptide-pulsed dendritic cells: Dependence on T cells, B7 costimulation, and T helper cell 1-associated cytokines
    • Zitvogel L, Mayordomo JI, Tjandrawan T, DeLeo AB, Clarke MR, Lotze MT, et al. Therapy of murine tumors with tumor peptide-pulsed dendritic cells: Dependence on T cells, B7 costimulation, and T helper cell 1-associated cytokines. J Exp Med 1996;183:87-97.
    • (1996) J Exp Med , vol.183 , pp. 87-97
    • Zitvogel, L.1    Mayordomo, J.I.2    Tjandrawan, T.3    DeLeo, A.B.4    Clarke, M.R.5    Lotze, M.T.6
  • 37
    • 0033939943 scopus 로고    scopus 로고
    • Activation of hepatic NKT cells and subsequent liver injury following administration of α-galactosylceramide
    • Osman Y, Kawamura T, Naito T, Takeda K, Van Kaer L, Okumura K, et al. Activation of hepatic NKT cells and subsequent liver injury following administration of α-galactosylceramide. Eur J Immunol 2000;30:1919-1928.
    • (2000) Eur J Immunol , vol.30 , pp. 1919-1928
    • Osman, Y.1    Kawamura, T.2    Naito, T.3    Takeda, K.4    Van Kaer, L.5    Okumura, K.6
  • 38
    • 0037787982 scopus 로고    scopus 로고
    • Activation of natural killer T cells by α-gatactosylceramide rapidly induces the full maturation of dendritic cells in vivo and thereby acts as an adjuvant for combined CD4 and CD8 T cell immunity to a coadministered protein
    • Fujii S, Shimizu K, Smith C, Bonifaz L, Steinman RM. Activation of natural killer T cells by α-gatactosylceramide rapidly induces the full maturation of dendritic cells in vivo and thereby acts as an adjuvant for combined CD4 and CD8 T cell immunity to a coadministered protein. J Exp Med 2003;198:267-279.
    • (2003) J Exp Med , vol.198 , pp. 267-279
    • Fujii, S.1    Shimizu, K.2    Smith, C.3    Bonifaz, L.4    Steinman, R.M.5
  • 39
    • 3042545974 scopus 로고    scopus 로고
    • The linkage of innate to adaptive immunity via maturing dendritic cells in vivo requires CD40 ligation in addition to antigen presentation and CD80/86 costimulation
    • Fujii S, Liu K, Smith C, Bonito AJ, Steinman RM. The linkage of innate to adaptive immunity via maturing dendritic cells in vivo requires CD40 ligation in addition to antigen presentation and CD80/86 costimulation. J Exp Med 2004;199:1607-1618.
    • (2004) J Exp Med , vol.199 , pp. 1607-1618
    • Fujii, S.1    Liu, K.2    Smith, C.3    Bonito, A.J.4    Steinman, R.M.5
  • 40
    • 10744230210 scopus 로고    scopus 로고
    • NKT cells enhance CD4+ and CD8+ T cells responses to soluble antigen in vivo through direct interaction with dendritic cells
    • Hermans IF, Silk JD, Gileadi U, Salio M, Mathew B, Ritter G, et al. NKT cells enhance CD4+ and CD8+ T cells responses to soluble antigen in vivo through direct interaction with dendritic cells. J Immunol 2003;171: 5140-5147.
    • (2003) J Immunol , vol.171 , pp. 5140-5147
    • Hermans, I.F.1    Silk, J.D.2    Gileadi, U.3    Salio, M.4    Mathew, B.5    Ritter, G.6
  • 41
    • 0033854136 scopus 로고    scopus 로고
    • The interface between innate and acquired immunity: Glycolipid antigen presentation by CD1d-expressing dendritic cells to NKT cells induces the differentiation of antigen-specific cytotoxic T lymphocytes
    • Nishimura T, Kitamura H, Iwakabe K, Yahata T, Ohta A, Sato M, et al. The interface between innate and acquired immunity: glycolipid antigen presentation by CD1d-expressing dendritic cells to NKT cells induces the differentiation of antigen-specific cytotoxic T lymphocytes. Int Immunol 2000;12:987-994.
    • (2000) Int Immunol , vol.12 , pp. 987-994
    • Nishimura, T.1    Kitamura, H.2    Iwakabe, K.3    Yahata, T.4    Ohta, A.5    Sato, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.