메뉴 건너뛰기




Volumn 2, Issue 1, 2006, Pages 95-101

Genomic-based biomarkers of drug-induced nephrotoxicity

Author keywords

Gene expression; Genomic biomarkers; Nephrotoxicity; Quantitative real time PCR; Toxicogenomics

Indexed keywords

BIOLOGICAL MARKER; NOTCH1 RECEPTOR;

EID: 33846301110     PISSN: 17425255     EISSN: None     Source Type: Journal    
DOI: 10.1517/17425255.2.1.95     Document Type: Review
Times cited : (24)

References (40)
  • 1
    • 0034779861 scopus 로고    scopus 로고
    • HUANG Q, DUNN RT, JAYADEV S et al.: Assessment of cisplatin-induced nephrotoxicity by microarray technology. Toxicol. Sci. (2001) 63(2):196-207. Compared gene expression profiles in rats treated with cisplatin against those treated with an inactive isomer.
    • HUANG Q, DUNN RT, JAYADEV S et al.: Assessment of cisplatin-induced nephrotoxicity by microarray technology. Toxicol. Sci. (2001) 63(2):196-207. Compared gene expression profiles in rats treated with cisplatin against those treated with an inactive isomer.
  • 2
    • 0036900945 scopus 로고    scopus 로고
    • Medical applications of microarray technologies: A regulatory science perspective
    • PETRICOIN EF 3rd, HACKETT JL, LESKO LJ et al.: Medical applications of microarray technologies: a regulatory science perspective. Nat. Genet. (2002) 32(Suppl.):474-479.
    • (2002) Nat. Genet , vol.32 , Issue.SUPPL. , pp. 474-479
    • PETRICOIN III, E.F.1    HACKETT, J.L.2    LESKO, L.J.3
  • 3
    • 12144290763 scopus 로고    scopus 로고
    • AMIN RP, VICKERS AE, SISTARE F et al.: Identification of putative gene based markers of renal toxicity. Environ. Health Perspect. (2004) 112(4):465-479. Compared gene expression profiles against three distinct classes of nephrotoxicants.
    • AMIN RP, VICKERS AE, SISTARE F et al.: Identification of putative gene based markers of renal toxicity. Environ. Health Perspect. (2004) 112(4):465-479. Compared gene expression profiles against three distinct classes of nephrotoxicants.
  • 4
    • 12144287350 scopus 로고    scopus 로고
    • Overview on the application of transcription profiling using selected nephrotoxicants for toxicology assessment
    • KRAMER JA, PETTIT SD, AMIN RP et al.: Overview on the application of transcription profiling using selected nephrotoxicants for toxicology assessment. Environ. Health Perspect. (2004) 112(4):460-464.
    • (2004) Environ. Health Perspect , vol.112 , Issue.4 , pp. 460-464
    • KRAMER, J.A.1    PETTIT, S.D.2    AMIN, R.P.3
  • 5
    • 0242412482 scopus 로고    scopus 로고
    • Adipsin, a biomarker of gastrointestinal toxicity mediated by a functional gamma-secretase inhibitor
    • SEARFOSS GH, JORDAN WH, CALLIGARO DO et al.: Adipsin, a biomarker of gastrointestinal toxicity mediated by a functional gamma-secretase inhibitor. J. Biol. Chem. (2003) 278(46):46107-46116.
    • (2003) J. Biol. Chem , vol.278 , Issue.46 , pp. 46107-46116
    • SEARFOSS, G.H.1    JORDAN, W.H.2    CALLIGARO, D.O.3
  • 7
    • 0036628957 scopus 로고    scopus 로고
    • Methapyrilene toxicity: Anchorage of pathologic observations to gene expression alterations
    • HAMADEH HK, KNIGHT BL, HAUGEN AC et al.: Methapyrilene toxicity: anchorage of pathologic observations to gene expression alterations. Toxicol. Pathol. (2002) 30(4):470-482.
    • (2002) Toxicol. Pathol , vol.30 , Issue.4 , pp. 470-482
    • HAMADEH, H.K.1    KNIGHT, B.L.2    HAUGEN, A.C.3
  • 8
    • 20944440313 scopus 로고    scopus 로고
    • Prediction of nephrotoxicant action and identification of candidate toxicity-related biomarkers
    • THUKRAL SK, NORDONE PJ, HU R et al.: Prediction of nephrotoxicant action and identification of candidate toxicity-related biomarkers. Toxicol. Pathol. (2005) 33(3):343-355.
    • (2005) Toxicol. Pathol , vol.33 , Issue.3 , pp. 343-355
    • THUKRAL, S.K.1    NORDONE, P.J.2    HU, R.3
  • 9
    • 0035016501 scopus 로고    scopus 로고
    • Unique gene expression patterns in liver and kidney associated with exposure to chemical toxicants
    • BARTOSIEWICZ MJ, JENKINS D, PENN S, EMERY J, BUCKPITT A: Unique gene expression patterns in liver and kidney associated with exposure to chemical toxicants. J. Pharmacol. Exp. Ther. (2001) 297(3):895-905.
    • (2001) J. Pharmacol. Exp. Ther , vol.297 , Issue.3 , pp. 895-905
    • BARTOSIEWICZ, M.J.1    JENKINS, D.2    PENN, S.3    EMERY, J.4    BUCKPITT, A.5
  • 10
    • 0035213686 scopus 로고    scopus 로고
    • Identification of toxicologically predictive gene sets using cDNA microarrays
    • THOMAS RS, RANK DR, PENN SG et al.: Identification of toxicologically predictive gene sets using cDNA microarrays. Mol. Pharmacol. (2001) 60(6):1189-1194.
    • (2001) Mol. Pharmacol , vol.60 , Issue.6 , pp. 1189-1194
    • THOMAS, R.S.1    RANK, D.R.2    PENN, S.G.3
  • 11
    • 0142128826 scopus 로고    scopus 로고
    • Gene expression analysis reveals chemical-specific profiles
    • HAMADEH HK, BUSHEL PR, JAYADEV S et al.: Gene expression analysis reveals chemical-specific profiles. ToxicoL Sci. (2002) 67(2):219-231.
    • (2002) ToxicoL Sci , vol.67 , Issue.2 , pp. 219-231
    • HAMADEH, H.K.1    BUSHEL, P.R.2    JAYADEV, S.3
  • 12
    • 2442571046 scopus 로고    scopus 로고
    • Microarray results improve significantly as hybridization approaches equilibrium
    • SARTOR M, SCHWANEKAMP J, HALBLEIB D et al.: Microarray results improve significantly as hybridization approaches equilibrium. Biotechniques (2004) 36(5):790-796.
    • (2004) Biotechniques , vol.36 , Issue.5 , pp. 790-796
    • SARTOR, M.1    SCHWANEKAMP, J.2    HALBLEIB, D.3
  • 14
    • 33846293202 scopus 로고    scopus 로고
    • Kidney
    • Eds, Academic Press, San Diego, US (2002):255-336. Comprehensive review of nephrotoxicants
    • KHAN KNAA CL: Kidney. In: Handbook of Toxicological Pathology. WM Haschek, CG Rousseaux, MA Wallig (Eds), Academic Press, San Diego, US (2002):255-336. Comprehensive review of nephrotoxicants.
    • Handbook of Toxicological Pathology
    • CL, K.K.1
  • 15
    • 0031887230 scopus 로고    scopus 로고
    • The measurement of renal injury
    • LOEB WF: The measurement of renal injury. Toxicol. Pathol. (1998) 26(1):26-28.
    • (1998) Toxicol. Pathol , vol.26 , Issue.1 , pp. 26-28
    • LOEB, W.F.1
  • 16
    • 0031783727 scopus 로고    scopus 로고
    • Treatment of acute renal failure
    • STAR RA: Treatment of acute renal failure. Kidney Int. (1998) 54(6):1817-1831.
    • (1998) Kidney Int , vol.54 , Issue.6 , pp. 1817-1831
    • STAR, R.A.1
  • 17
    • 0036314217 scopus 로고    scopus 로고
    • Kidney Injury Molecule-1 (KIM-1): A novel biomarker for human renal proximal tubule injury
    • HAN WK, BAILLY V, ABICHANDANI R, THADHANI R, BONVENTRE JV: Kidney Injury Molecule-1 (KIM-1): a novel biomarker for human renal proximal tubule injury. Kidney Int. (2002) 62(1):237-244.
    • (2002) Kidney Int , vol.62 , Issue.1 , pp. 237-244
    • HAN, W.K.1    BAILLY, V.2    ABICHANDANI, R.3    THADHANI, R.4    BONVENTRE, J.V.5
  • 18
    • 0036393899 scopus 로고    scopus 로고
    • CHARLWOOD J, SKEHEL JM, KING N et al.: Proteomic analysis of rat kidney cortex following treatment with gentamicin. J. Proteome. Res. (2002) 1(1):73-82. This paper was the first to measure KIM-1 in the urine of patients with acute renal failure.
    • CHARLWOOD J, SKEHEL JM, KING N et al.: Proteomic analysis of rat kidney cortex following treatment with gentamicin. J. Proteome. Res. (2002) 1(1):73-82. This paper was the first to measure KIM-1 in the urine of patients with acute renal failure.
  • 19
    • 0031823995 scopus 로고    scopus 로고
    • New insights into cyclosporine A nephrotoxicity by proteome analysis
    • AICHER L, WAHL D, ARCE A, GRENET O, STEINER S: New insights into cyclosporine A nephrotoxicity by proteome analysis. Electrophoresis (1998) 19(11):1998-2003.
    • (1998) Electrophoresis , vol.19 , Issue.11 , pp. 1998-2003
    • AICHER, L.1    WAHL, D.2    ARCE, A.3    GRENET, O.4    STEINER, S.5
  • 20
    • 15844382544 scopus 로고    scopus 로고
    • Development and validation of new screening tests for nephrotoxic effects
    • PRICE RG, TAYLOR SA, CHIVERS I et al.: Development and validation of new screening tests for nephrotoxic effects. Hum. Exp. Toxicol. (1996) 15(Suppl. 1):S10-S19.
    • (1996) Hum. Exp. Toxicol , vol.15 , Issue.SUPPL. 1
    • PRICE, R.G.1    TAYLOR, S.A.2    CHIVERS, I.3
  • 21
    • 0022551059 scopus 로고
    • Chronic gentamicin nephrotoxiciry. Continued tubular injury with preserved glomerular filtration function
    • HOUGHTON DC, LEE D, GILBERT DN, BENNETT WM: Chronic gentamicin nephrotoxiciry. Continued tubular injury with preserved glomerular filtration function. Am. J. Pathol. (1986) 123(1):183-194.
    • (1986) Am. J. Pathol , vol.123 , Issue.1 , pp. 183-194
    • HOUGHTON, D.C.1    LEE, D.2    GILBERT, D.N.3    BENNETT, W.M.4
  • 23
    • 12144286400 scopus 로고    scopus 로고
    • THOMPSON KL, AFSHARI CA, AMIN RP et al.: Identification of platform-independent gene expression markers of cisplatin nephrotoxicity. Environ. Health Perspect. (2004) 112(4):488-494. This is a cross-platform characterisation of cisplatin-induced gene expression changes.
    • THOMPSON KL, AFSHARI CA, AMIN RP et al.: Identification of platform-independent gene expression markers of cisplatin nephrotoxicity. Environ. Health Perspect. (2004) 112(4):488-494. This is a cross-platform characterisation of cisplatin-induced gene expression changes.
  • 24
    • 4644222253 scopus 로고    scopus 로고
    • Acute renal failure: From renal physiology to the renal transcriptome
    • SAFIRSTEIN RL: Acute renal failure: from renal physiology to the renal transcriptome. Kidney Int. Suppl. (2004) 91:S62-S66.
    • (2004) Kidney Int. Suppl , vol.91
    • SAFIRSTEIN, R.L.1
  • 25
    • 0036241814 scopus 로고    scopus 로고
    • Monitoring changes in gene expression in renal ischemia-reperfusion in the rat
    • YOSHIDA T, KURELLA M, BEATO F et al.: Monitoring changes in gene expression in renal ischemia-reperfusion in the rat. Kidney Int. (2002) 61(5):1646-1654.
    • (2002) Kidney Int , vol.61 , Issue.5 , pp. 1646-1654
    • YOSHIDA, T.1    KURELLA, M.2    BEATO, F.3
  • 26
    • 0036079677 scopus 로고    scopus 로고
    • Involvement of multiple kinase pathways in stimulation of gene transcription by hypertonicity
    • NAHM O, WOO SK, HANDLER JS, KWON HM: Involvement of multiple kinase pathways in stimulation of gene transcription by hypertonicity. Am. J. Physiol. Cell. Physiol. (2002) 282(1):C49-C58.
    • (2002) Am. J. Physiol. Cell. Physiol , vol.282 , Issue.1
    • NAHM, O.1    WOO, S.K.2    HANDLER, J.S.3    KWON, H.M.4
  • 27
    • 0037834732 scopus 로고    scopus 로고
    • A new approach to studying ochratoxin A (OTA)-induced nephrotoxicity: Expression profiling in vivo and in vitro employing cDNA microarrays
    • LUHE A, HILDEBRAND H, BACH U, DINGERMANN T, AHR HJ: A new approach to studying ochratoxin A (OTA)-induced nephrotoxicity: expression profiling in vivo and in vitro employing cDNA microarrays. Toxicol. Sci. (2003) 73(2):315-328.
    • (2003) Toxicol. Sci , vol.73 , Issue.2 , pp. 315-328
    • LUHE, A.1    HILDEBRAND, H.2    BACH, U.3    DINGERMANN, T.4    AHR, H.J.5
  • 28
    • 0036233677 scopus 로고    scopus 로고
    • Risk assessment of ochratoxin: Current views of the European Scientific Committee on Food, the JECFA and the Codex Committee on Food Additives and Contaminants
    • WALKER R: Risk assessment of ochratoxin: current views of the European Scientific Committee on Food, the JECFA and the Codex Committee on Food Additives and Contaminants. Adv. Exp. Med. Biol. (2002) 504:249-255.
    • (2002) Adv. Exp. Med. Biol , vol.504 , pp. 249-255
    • WALKER, R.1
  • 29
    • 2542479461 scopus 로고    scopus 로고
    • DAVIS JW 2nd, GOODSAID FM, BRAL CM et al.: Quantitative gene expression analysis in a nonhuman primate model of antibiotic-induced nephrotoxicity. Toxicol. Appl. Pharmacol. (2004) 200(1):16-26. This was the first published attempt to correlate gene expression changes in rats in a nonhuman primate model of drug-induced nephrotoxicity.
    • DAVIS JW 2nd, GOODSAID FM, BRAL CM et al.: Quantitative gene expression analysis in a nonhuman primate model of antibiotic-induced nephrotoxicity. Toxicol. Appl. Pharmacol. (2004) 200(1):16-26. This was the first published attempt to correlate gene expression changes in rats in a nonhuman primate model of drug-induced nephrotoxicity.
  • 30
    • 0037131165 scopus 로고    scopus 로고
    • Shedding of kidney injury molecule-1, a putative adhesion protein involved in renal regeneration
    • BAILLY V, ZHANG Z, MEIER W et al.: Shedding of kidney injury molecule-1, a putative adhesion protein involved in renal regeneration. J. Biol. Chem. (2002) 277(42):39739-39748.
    • (2002) J. Biol. Chem , vol.277 , Issue.42 , pp. 39739-39748
    • BAILLY, V.1    ZHANG, Z.2    MEIER, W.3
  • 31
    • 0027479575 scopus 로고
    • Urinary clusterin in chronic nephroroxicity in the rat
    • The authors proposed clusterin as a urinary protcomic marker of nephrotoxicity in rats
    • ETI S, CHENG CY, MARSHALL A, REIDENBERG MM: Urinary clusterin in chronic nephroroxicity in the rat. Proc. Soc. Exp. Biol. Med. (1993) 202(4):487-490. The authors proposed clusterin as a urinary protcomic marker of nephrotoxicity in rats.
    • (1993) Proc. Soc. Exp. Biol. Med , vol.202 , Issue.4 , pp. 487-490
    • ETI, S.1    CHENG, C.Y.2    MARSHALL, A.3    REIDENBERG, M.M.4
  • 33
    • 4544290091 scopus 로고    scopus 로고
    • VICKERS AE, ROSE K, FISHER R et al.: Kidney slices of human and rat to characterize cisplatin-induced injury on cellular pathways and morphology. Toxicol. Pathol. (2004) 32(5):577-590. This paper demonstrates the potential of using kidney slices as a genomics-based screening tool.
    • VICKERS AE, ROSE K, FISHER R et al.: Kidney slices of human and rat to characterize cisplatin-induced injury on cellular pathways and morphology. Toxicol. Pathol. (2004) 32(5):577-590. This paper demonstrates the potential of using kidney slices as a genomics-based screening tool.
  • 35
    • 0037444362 scopus 로고    scopus 로고
    • Contemporary issues in toxicology the role of metabonomics in toxicology and its evaluation by the COMET project
    • LINDON JC, NICHOLSON JK, HOLMES E et al.: Contemporary issues in toxicology the role of metabonomics in toxicology and its evaluation by the COMET project. Toxicol. Appl. Pharmacol. (2003) 187(3):137-146.
    • (2003) Toxicol. Appl. Pharmacol , vol.187 , Issue.3 , pp. 137-146
    • LINDON, J.C.1    NICHOLSON, J.K.2    HOLMES, E.3
  • 36
    • 19744374994 scopus 로고    scopus 로고
    • Combinatorial biomarkers: From early toxicology assays to patient population profiling
    • KOOP R: Combinatorial biomarkers: from early toxicology assays to patient population profiling. Drug Discov. Today (2005) 10(11):781-788.
    • (2005) Drug Discov. Today , vol.10 , Issue.11 , pp. 781-788
    • KOOP, R.1
  • 38
    • 33846300962 scopus 로고    scopus 로고
    • http://www.fda.gov/cder/guidance/6400fnl.pdf Guidance forindustry: pharmacogenomic data submissions. A guidance document from the FDA that established and encouraged voluntary submission of genomics data.
    • http://www.fda.gov/cder/guidance/6400fnl.pdf Guidance forindustry: pharmacogenomic data submissions. A guidance document from the FDA that established and encouraged voluntary submission of genomics data.
  • 39
    • 33846323569 scopus 로고    scopus 로고
    • http://www.ensembl.org/index.html
  • 40
    • 33846334390 scopus 로고    scopus 로고
    • http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=genomeprj


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.