-
1
-
-
0015987706
-
Adriamycin chemotherapy-efficacy, safety, and pharmacologic basis of an intermittent single high-dosage schedule
-
Benjamin RS, Wiernik PH, Bachur NR. Adriamycin chemotherapy-efficacy, safety, and pharmacologic basis of an intermittent single high-dosage schedule. Cancer 1974;33:19-27.
-
(1974)
Cancer
, vol.33
, pp. 19-27
-
-
Benjamin, R.S.1
Wiernik, P.H.2
Bachur, N.R.3
-
2
-
-
0033006172
-
A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics Adriamycin and daunorubicin
-
Gewirtz DA. A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics Adriamycin and daunorubicin. Biochem Pharmacol 1999;57:727-41.
-
(1999)
Biochem Pharmacol
, vol.57
, pp. 727-741
-
-
Gewirtz, D.A.1
-
3
-
-
0030713362
-
Anthracyclines in the treatment of cancer
-
Hortobagyi GN. Anthracyclines in the treatment of cancer. An overview. Drugs 1997;54 Suppl 4:1-7.
-
(1997)
An overview. Drugs
, vol.54
, Issue.SUPPL. 4
, pp. 1-7
-
-
Hortobagyi, G.N.1
-
4
-
-
0027977771
-
Anthracycline antibiotics in cancer therapy. Focus on drug resistance
-
Booser DJ, Hortobagyi GN. Anthracycline antibiotics in cancer therapy. Focus on drug resistance. Drugs 1994;47:223-58.
-
(1994)
Drugs
, vol.47
, pp. 223-258
-
-
Booser, D.J.1
Hortobagyi, G.N.2
-
5
-
-
0023153149
-
The human multidrug resistance (mdr1) gene. cDNA cloning and transcription initiation
-
Ueda K, Clark DP, Chen CJ, Roninson IB, Gottesman MM, Pastan I. The human multidrug resistance (mdr1) gene. cDNA cloning and transcription initiation. J Biol Chem 1987;262:505-8.
-
(1987)
J Biol Chem
, vol.262
, pp. 505-508
-
-
Ueda, K.1
Clark, D.P.2
Chen, C.J.3
Roninson, I.B.4
Gottesman, M.M.5
Pastan, I.6
-
6
-
-
0025267824
-
Multidrug resistance phenotype of human BRO melanoma cells transfected with a wild-type human mdr1 complementary DNA
-
Lincke CR, van der Bliek AM, Schuurhuis GJ, van der Velde-Koerts T, Smit JJ, Borst P. Multidrug resistance phenotype of human BRO melanoma cells transfected with a wild-type human mdr1 complementary DNA. Cancer Res 1990;50:1779-85.
-
(1990)
Cancer Res
, vol.50
, pp. 1779-1785
-
-
Lincke, C.R.1
van der Bliek, A.M.2
Schuurhuis, G.J.3
van der Velde-Koerts, T.4
Smit, J.J.5
Borst, P.6
-
7
-
-
0032211417
-
Multidrug resistance mediated by the ATP-binding cassette transporter protein MRP
-
Cole SP, Deeley RG. Multidrug resistance mediated by the ATP-binding cassette transporter protein MRP. Bioessays 1998;20:931-40.
-
(1998)
Bioessays
, vol.20
, pp. 931-940
-
-
Cole, S.P.1
Deeley, R.G.2
-
8
-
-
84988285644
-
Differential anthracycline sensitivity in two related human colon carcinoma cell lines expressing similar levels of P-glycoprotein
-
Boquete AL, Vargas Roig L, Lopez GA, et al. Differential anthracycline sensitivity in two related human colon carcinoma cell lines expressing similar levels of P-glycoprotein. Cancer Lett 2001;165:111-6.
-
(2001)
Cancer Lett
, vol.165
, pp. 111-116
-
-
Boquete, A.L.1
Vargas Roig, L.2
Lopez, G.A.3
-
9
-
-
13844259422
-
Clinical drug resistance: The role of factors other than P-glycoprotein
-
Kaye SB. Clinical drug resistance: the role of factors other than P-glycoprotein. Am J Med 1995;99:40-4S.
-
(1995)
Am J Med
, vol.99
-
-
Kaye, S.B.1
-
10
-
-
1642538437
-
Overexpression of Ssl2p confers resistance to Adriamycin and actinomycin D in Saccharomyces cerevisiae
-
Furuchi T, Nitta K, Takahashi T, Naganuma A. Overexpression of Ssl2p confers resistance to Adriamycin and actinomycin D in Saccharomyces cerevisiae. Biochem Biophys Res Commun 2004;314:844-8.
-
(2004)
Biochem Biophys Res Commun
, vol.314
, pp. 844-848
-
-
Furuchi, T.1
Nitta, K.2
Takahashi, T.3
Naganuma, A.4
-
11
-
-
3042671690
-
Functions of yeast helicase Ssl2p that are essential for viability are also involved in protection from the toxicity of Adriamycin
-
Furuchi T, Takahashi T, Tanaka S, Nitta K, Naganuma A. Functions of yeast helicase Ssl2p that are essential for viability are also involved in protection from the toxicity of Adriamycin. Nucleic Acids Res 2004;32:2578-85.
-
(2004)
Nucleic Acids Res
, vol.32
, pp. 2578-2585
-
-
Furuchi, T.1
Takahashi, T.2
Tanaka, S.3
Nitta, K.4
Naganuma, A.5
-
12
-
-
10044269626
-
A novel role for Bsd2 in the resistance of yeast to Adriamycin
-
Takahashi T, Furuchi T, Naganuma A. A novel role for Bsd2 in the resistance of yeast to Adriamycin. J Cell Physiol 2005;202:100-4.
-
(2005)
J Cell Physiol
, vol.202
, pp. 100-104
-
-
Takahashi, T.1
Furuchi, T.2
Naganuma, A.3
-
13
-
-
0037368028
-
The Ark1/Prk1 family of protein kinases. Regulators of endocytosis and the actin skeleton
-
Smythe E, Ayscough KK. The Ark1/Prk1 family of protein kinases. Regulators of endocytosis and the actin skeleton. EMBO Rep 2003;4:246-51.
-
(2003)
EMBO Rep
, vol.4
, pp. 246-251
-
-
Smythe, E.1
Ayscough, K.K.2
-
14
-
-
0033545185
-
Regulation of the actin cytoskeleton organization in yeast by a novel serine/threonine kinase Prk1p
-
Zeng G, Cai M. Regulation of the actin cytoskeleton organization in yeast by a novel serine/threonine kinase Prk1p. J Cell Biol 1999;144:71-82.
-
(1999)
J Cell Biol
, vol.144
, pp. 71-82
-
-
Zeng, G.1
Cai, M.2
-
15
-
-
0035658368
-
Regulation of yeast actin cytoskeleton-regulatory complex Pan1p/Sla1p/End3p by serine/threonine kinase Prk1p
-
Zeng G, Yu X, Cai M. Regulation of yeast actin cytoskeleton-regulatory complex Pan1p/Sla1p/End3p by serine/threonine kinase Prk1p. Mol Biol Cell 2001;12:3759-72.
-
(2001)
Mol Biol Cell
, vol.12
, pp. 3759-3772
-
-
Zeng, G.1
Yu, X.2
Cai, M.3
-
16
-
-
0042733637
-
Differential requirements for AP-2 in clathrin-mediated endocytosis
-
Conner SD, Schmid SL. Differential requirements for AP-2 in clathrin-mediated endocytosis. J Cell Biol 2003;162:773-80.
-
(2003)
J Cell Biol
, vol.162
, pp. 773-780
-
-
Conner, S.D.1
Schmid, S.L.2
-
17
-
-
0034012498
-
GFAT as a target molecule of methylmercury toxicity in Saccharomyces cerevisiae
-
Naganuma A, Miura N, Kaneko S, et al. GFAT as a target molecule of methylmercury toxicity in Saccharomyces cerevisiae. FASEB J 2000;14:968-72.
-
(2000)
FASEB J
, vol.14
, pp. 968-972
-
-
Naganuma, A.1
Miura, N.2
Kaneko, S.3
-
18
-
-
25144485014
-
Overexpression of Rad23 confers resistance to methylmercury in Saccharomyces cerevisiae via inhibition of the degradation of ubiquitinated proteins
-
Hwang GW, Sasaki D, Naganuma A. Overexpression of Rad23 confers resistance to methylmercury in Saccharomyces cerevisiae via inhibition of the degradation of ubiquitinated proteins. Mol Pharmacol 2005;68:1074-8.
-
(2005)
Mol Pharmacol
, vol.68
, pp. 1074-1078
-
-
Hwang, G.W.1
Sasaki, D.2
Naganuma, A.3
-
19
-
-
0036582751
-
A ubiquitin-proteasome system is responsible for the protection of yeast and human cells against methylmercury
-
Hwang GW, Furuchi T, Naganuma A. A ubiquitin-proteasome system is responsible for the protection of yeast and human cells against methylmercury. FASEB J 2002;16:709-11.
-
(2002)
FASEB J
, vol.16
, pp. 709-711
-
-
Hwang, G.W.1
Furuchi, T.2
Naganuma, A.3
-
20
-
-
0033594087
-
Novel protein kinases Ark1p and Prk1p associate with and regulate the cortical actin cytoskeleton in budding yeast
-
Cope MJ, Yang S, Shang C, Drubin DG. Novel protein kinases Ark1p and Prk1p associate with and regulate the cortical actin cytoskeleton in budding yeast. J Cell Biol 1999;144:1203-18.
-
(1999)
J Cell Biol
, vol.144
, pp. 1203-1218
-
-
Cope, M.J.1
Yang, S.2
Shang, C.3
Drubin, D.G.4
-
21
-
-
0344279906
-
EH domain proteins Pan1p and End3p are components of a complex that plays a dual role in organization of the cortical actin cytoskeleton and endocytosis in Saccharomyces cerevisiae
-
Tang HY, Munn A, Cai M. EH domain proteins Pan1p and End3p are components of a complex that plays a dual role in organization of the cortical actin cytoskeleton and endocytosis in Saccharomyces cerevisiae. Mol Cell Biol 1997;17:4294-304.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 4294-4304
-
-
Tang, H.Y.1
Munn, A.2
Cai, M.3
-
22
-
-
0037089086
-
Sla1p couples the yeast endocytic machinery to proteins regulating actin dynamics
-
Warren DT, Andrews PD, Gourlay CW, Ayscough KR. Sla1p couples the yeast endocytic machinery to proteins regulating actin dynamics. J Cell Sci 2002;115:1703-15.
-
(2002)
J Cell Sci
, vol.115
, pp. 1703-1715
-
-
Warren, D.T.1
Andrews, P.D.2
Gourlay, C.W.3
Ayscough, K.R.4
-
23
-
-
0037018152
-
Identification of an adaptor-associated kinase, AAK1, as a regulator of clathrin-mediated endocytosis
-
Conner SD, Schmid SL. Identification of an adaptor-associated kinase, AAK1, as a regulator of clathrin-mediated endocytosis. J Cell Biol 2002;156:921-9.
-
(2002)
J Cell Biol
, vol.156
, pp. 921-929
-
-
Conner, S.D.1
Schmid, S.L.2
-
24
-
-
0037018156
-
Phosphorylation of the AP2μ subunit by AAK1 mediates high affinity binding to membrane protein sorting signals
-
Ricotta D, Conner SD, Schmid SL, von Figura K, Honing S. Phosphorylation of the AP2μ subunit by AAK1 mediates high affinity binding to membrane protein sorting signals. J Cell Biol 2002;156:791-5.
-
(2002)
J Cell Biol
, vol.156
, pp. 791-795
-
-
Ricotta, D.1
Conner, S.D.2
Schmid, S.L.3
von Figura, K.4
Honing, S.5
-
25
-
-
0036300863
-
CK2 and GAK/auxilin2 are major protein kinases in clathrin-coated vesicles
-
Korolchuk VI, Banting G. CK2 and GAK/auxilin2 are major protein kinases in clathrin-coated vesicles. Traffic 2002;3:428-39.
-
(2002)
Traffic
, vol.3
, pp. 428-439
-
-
Korolchuk, V.I.1
Banting, G.2
-
26
-
-
0034118754
-
Identification of the universal cofactor (auxilin 2) in clathrin coat dissociation
-
Umeda A, Meyerholz A, Ungewickell E. Identification of the universal cofactor (auxilin 2) in clathrin coat dissociation. Eur J Cell Biol 2000;79:336-42.
-
(2000)
Eur J Cell Biol
, vol.79
, pp. 336-342
-
-
Umeda, A.1
Meyerholz, A.2
Ungewickell, E.3
-
27
-
-
0035196516
-
In vivo role for actin-regulating kinases in endocytosis and yeast epsin phosphorylation
-
Watson HA, Cope MJ, Groen AC, Drubin DG, Wendland B. In vivo role for actin-regulating kinases in endocytosis and yeast epsin phosphorylation. Mol Biol Cell 2001;12:3668-79.
-
(2001)
Mol Biol Cell
, vol.12
, pp. 3668-3679
-
-
Watson, H.A.1
Cope, M.J.2
Groen, A.C.3
Drubin, D.G.4
Wendland, B.5
-
28
-
-
0042420298
-
The actin-regulating kinase Prk1p negatively regulates Scd5p, a suppressor of clathrin deficiency, in actin organization and endocytosis
-
Henry KR, D'Hondt K, Chang JS, et al. The actin-regulating kinase Prk1p negatively regulates Scd5p, a suppressor of clathrin deficiency, in actin organization and endocytosis. Curr Biol 2003;13:1564-9.
-
(2003)
Curr Biol
, vol.13
, pp. 1564-1569
-
-
Henry, K.R.1
D'Hondt, K.2
Chang, J.S.3
-
29
-
-
0038159267
-
An interaction between Sla1p and Sla2p plays a role in regulating actin dynamics and endocytosis in budding yeast
-
Gourlay CW, Dewar H, Warren DT, Costa R, Satish N, Ayscough KR. An interaction between Sla1p and Sla2p plays a role in regulating actin dynamics and endocytosis in budding yeast. J Cell Sci 2003;116:2551-64.
-
(2003)
J Cell Sci
, vol.116
, pp. 2551-2564
-
-
Gourlay, C.W.1
Dewar, H.2
Warren, D.T.3
Costa, R.4
Satish, N.5
Ayscough, K.R.6
-
30
-
-
0032934806
-
Sla1p is a functionally modular component of the yeast cortical actin cytoskeleton required for correct localization of both Rho1p-GTPase and Sla2p, a protein with talin homology
-
Ayscough KR, Eby JJ, Lila T, Dewar H, Kozminski KG, Drubin DG. Sla1p is a functionally modular component of the yeast cortical actin cytoskeleton required for correct localization of both Rho1p-GTPase and Sla2p, a protein with talin homology. Mol Biol Cell 1999;10:1061-75.
-
(1999)
Mol Biol Cell
, vol.10
, pp. 1061-1075
-
-
Ayscough, K.R.1
Eby, J.J.2
Lila, T.3
Dewar, H.4
Kozminski, K.G.5
Drubin, D.G.6
-
31
-
-
0036196880
-
The novel adaptor protein, Mti1p, and Vrp1p, a homolog of Wiskott-Aldrich syndrome protein-interacting protein (WIP), may antagonistically regulate type I myosins in Saccharomyces cerevisiae
-
Mochida J, Yamamoto T, Fujimura-Kamada K, Tanaka K. The novel adaptor protein, Mti1p, and Vrp1p, a homolog of Wiskott-Aldrich syndrome protein-interacting protein (WIP), may antagonistically regulate type I myosins in Saccharomyces cerevisiae. Genetics 2002;160:923-34.
-
(2002)
Genetics
, vol.160
, pp. 923-934
-
-
Mochida, J.1
Yamamoto, T.2
Fujimura-Kamada, K.3
Tanaka, K.4
-
32
-
-
0034887843
-
The yeast Rvs161 and Rvs167 proteins are involved in secretory vesicles targeting the plasma membrane and in cell integrity
-
Breton AM, Schaeffer J, Aigle M. The yeast Rvs161 and Rvs167 proteins are involved in secretory vesicles targeting the plasma membrane and in cell integrity. Yeast 2001;18:1053-68.
-
(2001)
Yeast
, vol.18
, pp. 1053-1068
-
-
Breton, A.M.1
Schaeffer, J.2
Aigle, M.3
-
33
-
-
0034157875
-
Mammalian tumor susceptibility gene 101 (TSG101) and the yeast homologue, Vps23p, both function in late endosomal trafficking
-
Babst M, Odorizzi G, Estepa EJ, Emr SD. Mammalian tumor susceptibility gene 101 (TSG101) and the yeast homologue, Vps23p, both function in late endosomal trafficking. Traffic 2000;1:248-58.
-
(2000)
Traffic
, vol.1
, pp. 248-258
-
-
Babst, M.1
Odorizzi, G.2
Estepa, E.J.3
Emr, S.D.4
-
34
-
-
0028800173
-
VPS27 controls vacuolar and endocytic traffic through a prevacuolar compartment in Saccharomyces cerevisiae
-
Piper RC, Cooper AA, Yang H, Stevens TH. VPS27 controls vacuolar and endocytic traffic through a prevacuolar compartment in Saccharomyces cerevisiae. J Cell Biol 1995;131:603-17.
-
(1995)
J Cell Biol
, vol.131
, pp. 603-617
-
-
Piper, R.C.1
Cooper, A.A.2
Yang, H.3
Stevens, T.H.4
-
35
-
-
0029905732
-
Anticancer drugs, ionophoric peptides, and steroids as substrates of the yeast multidrug transporter Pdr5p
-
Kolaczkowski M, van der Rest M, Cybularz-Kolaczkowska A, Soumillion JP, Konings WN, Goffeau A. Anticancer drugs, ionophoric peptides, and steroids as substrates of the yeast multidrug transporter Pdr5p. J Biol Chem 1996;271:31543-8.
-
(1996)
J Biol Chem
, vol.271
, pp. 31543-31548
-
-
Kolaczkowski, M.1
van der Rest, M.2
Cybularz-Kolaczkowska, A.3
Soumillion, J.P.4
Konings, W.N.5
Goffeau, A.6
-
36
-
-
0030041980
-
The yeast multidrug transporter Pdr5 of the plasma membrane is ubiquitinated prior to endocytosis and degradation in the vacuole
-
Egner R, Kuchler K. The yeast multidrug transporter Pdr5 of the plasma membrane is ubiquitinated prior to endocytosis and degradation in the vacuole. FEBS Lett 1996;378:177-81.
-
(1996)
FEBS Lett
, vol.378
, pp. 177-181
-
-
Egner, R.1
Kuchler, K.2
-
37
-
-
0028783747
-
Endocytosis and vacuolar degradation of the plasma membrane-localized Pdr5 ATP-binding cassette multidrug transporter in Saccharomyces cerevisiae
-
Egner R, Mahe Y, Pandjaitan R, Kuchler K. Endocytosis and vacuolar degradation of the plasma membrane-localized Pdr5 ATP-binding cassette multidrug transporter in Saccharomyces cerevisiae. Mol Cell Biol 1995;15:5879-87.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 5879-5887
-
-
Egner, R.1
Mahe, Y.2
Pandjaitan, R.3
Kuchler, K.4
-
38
-
-
0025322402
-
Characterization of Adriamycin-resistant human breast cancer cells which display overexpression of a novel resistance-related membrane protein
-
Chen YN, Mickley LA, Schwartz AM, Acton EM, Hwang JL, Fojo AT, Characterization of Adriamycin-resistant human breast cancer cells which display overexpression of a novel resistance-related membrane protein. J Biol Chem 1990;265:10073-80.
-
(1990)
J Biol Chem
, vol.265
, pp. 10073-10080
-
-
Chen, Y.N.1
Mickley, L.A.2
Schwartz, A.M.3
Acton, E.M.4
Hwang, J.L.5
Fojo, A.T.6
-
39
-
-
0031436056
-
The 95-kilodalton membrane glycoprotein overexpressed in novel multidrug-resistant breast cancer cells is NCA, the nonspecific cross-reacting antigen of carcinoembryonic antigen
-
Ross DD, Gao Y, Yang W, Leszyk J, Shively J, Doyle LA. The 95-kilodalton membrane glycoprotein overexpressed in novel multidrug-resistant breast cancer cells is NCA, the nonspecific cross-reacting antigen of carcinoembryonic antigen. Cancer Res 1997;57:5460-4.
-
(1997)
Cancer Res
, vol.57
, pp. 5460-5464
-
-
Ross, D.D.1
Gao, Y.2
Yang, W.3
Leszyk, J.4
Shively, J.5
Doyle, L.A.6
-
40
-
-
0004549003
-
Synthesis of Adriamycin-coupled polyglutaraldehyde microspheres and evaluation of their cytostatic activity
-
Tokes ZA, Rogers KE, Rembaum A. Synthesis of Adriamycin-coupled polyglutaraldehyde microspheres and evaluation of their cytostatic activity. Proc Natl Acad Sci U S A 1982;79:2026-30,
-
(1982)
Proc Natl Acad Sci U S A
, vol.79
, pp. 2026-2030
-
-
Tokes, Z.A.1
Rogers, K.E.2
Rembaum, A.3
-
41
-
-
0019986638
-
The anticancer agent Adriamycin can be actively cytotoxic without entering cells
-
Triton TR, Yee G. The anticancer agent Adriamycin can be actively cytotoxic without entering cells. Science 1982;217:248-50.
-
(1982)
Science
, vol.217
, pp. 248-250
-
-
Triton, T.R.1
Yee, G.2
-
42
-
-
0022504644
-
Changes in biophysical parameters and in phospholipid composition associated with resistance to doxorubicin
-
Tapiero H, Mishal Z, Wioland M, Silber A, Fourcade A, Zwingelstein G. Changes in biophysical parameters and in phospholipid composition associated with resistance to doxorubicin. Anticancer Res 1986;6:649-52.
-
(1986)
Anticancer Res
, vol.6
, pp. 649-652
-
-
Tapiero, H.1
Mishal, Z.2
Wioland, M.3
Silber, A.4
Fourcade, A.5
Zwingelstein, G.6
-
43
-
-
33645292025
-
Membrane microdomains, caveolae, and caveolar endocytosis of sphingolipids (review)
-
Cheng ZJ, Deep Singh R, Marks DL, Pagano RE. Membrane microdomains, caveolae, and caveolar endocytosis of sphingolipids (review). Mol Membr Biol 2006;23:101-10.
-
(2006)
Mol Membr Biol
, vol.23
, pp. 101-110
-
-
Cheng, Z.J.1
Deep Singh, R.2
Marks, D.L.3
Pagano, R.E.4
-
44
-
-
0025183303
-
Interaction of anthracyclinic antibiotics with cytoskeletal components of cultured carcinoma cells (CG5)
-
Molinari A, Calcabrini A, Crateri P, Arancia G. Interaction of anthracyclinic antibiotics with cytoskeletal components of cultured carcinoma cells (CG5). Exp Mol Pathol 1990;53:11-33.
-
(1990)
Exp Mol Pathol
, vol.53
, pp. 11-33
-
-
Molinari, A.1
Calcabrini, A.2
Crateri, P.3
Arancia, G.4
-
45
-
-
0026646798
-
Interaction of cardiac α-actinin and actin in the presence of doxorubicin
-
DalleDonne I, Milzani A, Contini P, Bernardini G, Colombo R. Interaction of cardiac α-actinin and actin in the presence of doxorubicin. Exp Mol Pathol 1992;55:229-38.
-
(1992)
Exp Mol Pathol
, vol.55
, pp. 229-238
-
-
DalleDonne, I.1
Milzani, A.2
Contini, P.3
Bernardini, G.4
Colombo, R.5
|