In vivo role for actin-regulating kinases in endocytosis and yeast epsin phosphorylation

Molecular Biology of the Cell

Volumn 12, Issue 11, 2001, Pages 3668-3679

  Watson, H A ^a   Cope, M J T V ^a   Groen, A C ^a   Drubin, D G ^a   Wendland, B ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN REGULATING KINASE; EPSIN; GLUTAMIC ACID; PHOSPHOTRANSFERASE; THREONINE; UNCLASSIFIED DRUG;

ARTICLE; DEPHOSPHORYLATION; ENDOCYTOSIS; ENZYME ANALYSIS; GENOTYPE; IMMUNOPRECIPITATION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; YEAST;

EID: 0035196516     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.12.11.3668     Document Type: Article

References (34)

1. Endocytosis and the development of cell polarity in yeast require a dynamic F-actin cytoskeleton
2. Mapping of Eps15 domains involved in its targeting to clathrin-coated pits
3. eps15 and eps15R are essential components of the endocytic pathway
4. Epsin is an EH-domain-binding protein implicated in clathrin-mediated endocytosis
5. The interaction of epsin and Eps15 with the clathrin adaptor AP-2 is inhibited by mitotic phosphorylation and enhanced by stimulation-dependent dephosphorylation in nerve terminals
6. Novel protein kinases Ark1p and Prk1p associate with and regulate the cortical actin cytoskeleton in budding yeast
7. The AP-3 adaptor complex is essential for cargo-selective transport to the yeast vacuole
8. Structure and Asn-Pro-Phe binding pocket of the Eps15 homology domain
9. Molecular mechanism of NPF recognition by EH domains
10. Synthetic-lethal interactions identify two novel genes, SLA1 and SLA2, that control membrane cytoskeleton assembly in Saccharomyces cerevisiae
11. Splice variants of intersectin are components of the endocytic machinery in neurons and nonneuronal cells
12. Epsin 1 undergoes nucleocytosolic shuttling and its eps15 interactor NH(2)-terminal homology (ENTH) domain, structurally similar to Armadillo and HEAT repeats, interacts with the transcription factor promyelocytic leukemia Zn(2)+ finger protein (PLZF)
13. Role of the ENTH domain in phosphatidylino-sitol-4,5-bisphosphate binding and endocytosis
14. Identification of a novel domain shared by putative components of the endocytic and cytoskeletal machinery
15. Structural rearrangements of tubulin and actin during the cell cycle of the yeast Saccharomyces
16. Visualization of receptor-mediated endocytosis in yeast
17. SCD5, a suppressor of clathrin deficiency, encodes a novel protein with a late secretory function in yeast
18. Molecular links between endocytosis and the actin cytoskeleton
19. The epsins define a family of proteins that interact with components of the clathrin coat and contain a new protein module
20. Epidermal growth factor pathway substrate 15, Eps15
21. Clathrin-coated vesicle formation and protein sorting: An integrated process
22. Role of phosphorylation in regulation of the assembly of endocytic coat complexes
23. Systematic identification of mitotic phosphoproteins
24. The EH-domain-containing protein Pan1 is required for normal organization of the actin cytoskeleton in Saccharomyces cerevisiae
25. EH domain proteins Pan1p and End3p are components of a complex that plays a dual role in organization of the cortical actin cytoskeleton and endocytosis in Saccharomyces cerevisiae
26. PAK1, a gene that can regulate p53 activity in yeast
27. A new vital stain for visualizing vacuolar membrane dynamics and endocytosis in yeast
28. Pan1p, yeast eps15, functions as a multivalent adaptor that coordinates protein-protein interactions essential for endocytosis
29. A novel fluorescence-activated cell sorter-based screen for yeast endocytosis mutants identifies a yeast homologue of mammalian eps15
30. Yeast epsins contain an essential N-terminal ENTH domain, bind clathrin and are required for endocytosis
31. A protein-binding domain, EH, identified in the receptor tyrosine kinase substrate Eps15 and conserved in evolution
32. Regulation of the actin cytoskeleton organization in yeast by a novel serine/threonine kinase Prk1p
33. Isolation of yeast mutants defective for localization of vacuolar vital dyes
34. Mutations altering the mitochondrial-cytoplasmic distribution of Mod5p implicate the actin cytoskeleton and mRNA 3′ ends and/or protein synthesis in mitochondrial delivery