Mobilization of bone marrow-derived hematopoietic and endothelial stem cells after orthotopic liver transplantation and liver resection

Stem Cells

Volumn 24, Issue 12, 2006, Pages 2817-2825

  Lemoli, Roberto M ^a,b,d   Catani, Lucia ^a,b   Talarico, Simona ^a,b   Loggi, Elisabetta ^a,b   Gramenzi, Annagiulia ^a,b   Baccarani, Umberto ^c   Fogli, Miriam ^a,b   Grazi, Gian Luca ^b   Aluigi, Michela ^a,b   Marzocchi, Giulia ^a,b   Bernardi, Mauro ^a,b   Pinna, Antonio ^b   Bresadola, Fabrizio ^c   Baccarani, Michele ^a,b   Andreone, Pietro ^a,b  

^a Inst Hematol/Med Oncol Seragnoli   (Italy)

^b UNIVERSITY OF BOLOGNA   (Italy)

^c UNIVERSITY OF UDINE   (Italy)

^d Center for Stem Cell Research   (Italy)

Author keywords

Hematopoietic and endothelial stem cells; Orthotopic liver transplantation; Spontaneous mobilization

Indexed keywords

ALPHA FETOPROTEIN; CD133 ANTIGEN; CD34 ANTIGEN; CYCLOSPORIN; CYTOKERATIN 19; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 6; SCATTER FACTOR; STEM CELL FACTOR; STEROID; TACROLIMUS; TRANSCRIPTION FACTOR GATA 4; VASCULOTROPIN;

ADULT; AGED; ARTICLE; BONE MARROW CELL; CELL MOTILITY; CLINICAL ARTICLE; CLONOGENIC ASSAY; COLONY FORMING UNIT; CONTROLLED STUDY; ENDOTHELIUM CELL; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; HEMATOPOIETIC CELL; HUMAN; HUMAN CELL; KIDNEY FAILURE; LIVER CELL CARCINOMA; LIVER RESECTION; LIVER TRANSPLANTATION; MALE; PHENOTYPE; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADULT; AGED; ANTIGENS, CD34; BIOLOGICAL MARKERS; BLOOD CELLS; BONE MARROW CELLS; CELL MOVEMENT; CYTOKINES; ENDOTHELIAL CELLS; EPITHELIAL CELLS; FEMALE; HEMATOPOIETIC STEM CELLS; HEPATECTOMY; HUMANS; LIVER; LIVER TRANSPLANTATION; MALE; MIDDLE AGED; PHENOTYPE;

ANIMALIA;

EID: 33846102941     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1634/stemcells.2006-0333     Document Type: Article

References (52)

1. Alison MR, Poulsom R, Forbes SJ. Update on hepatic stem cells. Liver 2001;21:367-373.
2. Crosby HA, Kelly DA, Strain AJ. Human hepatic stem-like cells isolated using c-kit or CD34 can differentiate into biliary epithelium. Gastroenterology 2001;120:534-544.
3. Lagasse E, Connors H, Al-Dhalimy M et al. Purified hematopoietic stem cells can differentiate into hepatocytes in vivo. Nat Med 2000;6:1229-1234.
4. Petersen BE, Bowen WC, Patrene KD et al. Bone marrow as a potential source of hepatic oval cells. Science 1999;284:1168-1170.
5. Theise ND, Badve S, Saxena R et al. Derivation of hepatocytes from bone marrow cells in mice after radiation-induced myeloablation. Hepatology 2000;31:235-240.
6. Wang X, Ge S, McManara G et al. Albumin-expressing hepatocyte-like cells develop in the livers of immune-deficient mice that received transplants of highly purified human hematopoietic stem cells. Blood 2003;101:4201-4208.
7. Krause DS, Theise ND, Collector MI et al. Multi-organ, multi-lineage engraftment by a single bone marrow-derived stem cell. Cell 2001;105:369-377.
8. Alison MR, Poulsom R, Jaffery R et al. Hepatocytes from non-hepatic adult stem cells. Nature 2000;406:257.
9. Theise ND, Nimmakayalu M, Gardner R et al. Liver from bone marrow in humans. Hepatology 2000;32:11-16.
10. Willenbring H, Bailey AS, Foster M et al. Myelomonocytic cells are sufficient for therapeutic cell fusion in liver. Nat Med 2004;10:744-748.
11. Camargo FD, Finegold M, Goodell MA. Hematopoietic myelomonocytic cells are the major source of hepatocyte fusion partners. J Clin Invest 2004;9:1266-1270.
12. Harris RG, Herzog EL, Bruscia EM et al. Lack of fusion requirement for development of bone marrow-derived epithelia. Science 2004;305:90-93.
13. Jang YY, Collector MI, Baylin SB et al. Hematopoietic stem cells convert into liver cells within days without fusion. Nat Cell Biol 2004;6:532-539.
14. Korbling M, Katz RL, Khanna A et al. Hepatocytes and hepithelial cells of donor origin in recipients of peripheral blood stem cells. N Engl J Med 2002;346:738-746.
15. Danet GH, Luongo JL, Butler G et al. C1qRp defines a new human stem cell population with hematopoietic and hepatic potential. Proc Natl Acad Sci U S A 2002;99:10441-10445.
16. Zhao Y, Glesne D, Huberman E. A human peripheral blood monocyte-derived subset acts as pluripotent stem cells. Proc Natl Acad Sci U S A 2003;100:2426-2431.
17. Wulf GG, Luo K-L, Jackson KA et al. Cells of the hepatic side population contribute to liver regeneration and can be replenished by bone marrow stem cells. Haematologica 2003;88:368-378.
18. Jiang Y, Jahagirdar BN, Reinhardt RL et al. Pluripotency of mesenchymal stem cells derived from adult marrow. Nature 2002;418:41-49.
19. Schwartz RE, Reyes M, Koodie L et al. Multipotent adult progenitor cells from bone marrow differentiate into functional hepatocyte-like cells. J Clin Invest 2002;109:1291-1302.
20. Korbling M, Estrov Z. Adult stem cells for tissue repair-a new therapeutic concept? N Engl J Med 2003;349:570-582.
21. Lemoli RM, Bertolini F, Cancedda R et al. Stem cell plasticity: time for a reappraisal? Haematologica 2005;90:360-381.
22. + stem cell recruitment to the liver. J Clin Invest 2003;112:160-169.
23. Yannaki E, Athanasiou E, Xagorari A et al. G-CSF-primed hematopoietic stem cells or G-CSF per se accelerate recovery and improve survival after liver injury, predominantly by promoting endogenous repair programs. Exp Hematol 2005;33:108-119.
24. Gehling UM, Willems M, Dandri M et al. Partial hepatectomy induces mobilization of a unique population of hematopoietic progenitor cells in human healthy liver donors. J Hepatol 2005;43:845-853.
25. Lemoli RM, Tafuri A, Fortuna A et al. Cycling status of CD 34+ cells mobilized into peripheral blood of healthy donors by recombinant human granulocyte colony-stimulating factor. Blood 1997;89:1189-1196.
26. Lemoli RM, Ferrari D, Fogli M et al. Extracellular nucleotides are potent stimulators of human hematopoietic stem cells in vitro and in vivo. Blood 2004;104:1662-1670.
27. Collins RH, Anastasi J, Terstappen LW et al. Brief report: Donor-derived long-term multilineage hematopoiesis in a liver-transplant recipient. N Engl J Med 1993;328:762-765.
28. Petit I, Kravitz-Szyper M, Nagler A et al. G-CSF induces stem cell mobilizatio by decreasing bone marrow SDF-1 and upregulating CXCR4. Nat Immunol 2002;3:687-694.
29. Idilman R, Erden E, Kuzu I et al. Recipient-derived hepatocytes in sex-mismatched liver allografts after liver transplantation: early versus late transplant biopsies. Transplantation 2004;78:1647-1652.
30. Fujii H, Hirose T, Oe S et al. Contribution of bone marrow cells to liver regeneration after partial hepatectomy in mice. J Hepatol 2002;36:653-659.
31. Dirsch O, Chi H, Gu YL et al. Influence of stem cell mobilization and liver regeneration on hepatic parenchimal chimerism in the rat. Transplantation 2006;81:1695-1699.
32. Liu F, Pan XB, Chen GD et al. Hematopoietic stem cell mobilization after rat partial orthotopic liver transplantation. Transplantation Proceedings 2006;38:1603-1609.
33. Liu F, Pan XB, Chen GD et al. Hematopoietic stem cell mobilization by granulocyte colony-stimulating factor partly contribute to liver graft regeneration after partial orthotopic liver transplantation. Liver transplantation 2006;12:1129-1137.
34. Ratajczak MZ, Majka M, Kucia M et al. Expression of functional CXCR4 by muscle satellite cells and secretion of SDF-1 by muscle-derived fibroblasts is associated with the presence of both muscle progenitors in bone marrow and hematopoietic stem/progenitor cells in muscles. STEM CELLS 2003;21:363-371.
35. Wojakowski W, Tendera M, Michalowska A et al. Mobilization of CD34/CXCR4+, CD34/CD117+, c-met+ Stem Cells, and Mononuclear Cells Expressing Early Cardiac, Muscle, and Endothelial Markers into Peripheral Blood in Patients with Acute Myocardial Infarction. Circulation 2004;110:3213-3220.
36. Kocher AA, Schuster MD, Szabolcs MJ et al. Neovascularization of ischemic myocardium by human bone-marrow-derived angioblasts prevents cardiomyocyte apoptosis, reduces remodeling and improves cardiac function. Nat Med 2001;7:430-436.
37. Gill M, Dias S, Hattori K et al. Vascular trauma induces rapid but transient mobilization of VEGFR2+AC133+ endothelial precursors cells. Circ Res 2001;88:167-174.
38. + cells identifies a population of functional endothelial precursors. Blood 2000;95:952-958.
39. Shintani S, Murohara T, Ikeda H et al. Mobilization of endothelial progenitor cells in patients with acute myocardial infarction. Circulation 2001;103:2776-2779.
40. Massa M, Rosti V, Ferrario M et al. Increased circulating hematopoietic and endothelial progenitor cells in the early phase of acute myocardial infarction. Blood 2005;105:199-206.
41. Kucia M, Ratajczak J, Reca R et al. Tissue-specific muscle, neural and liver stem/progenitor cells reside in the bone marrow, respond to an SDF-1 gradient and are mobilized into peripheral blood during stress and tissue injury. Blood Cells Mol Dis 2004;32:52-57.
42. Fogt F, Beyser KH, Poremba C et al. Recipient-derived hepatocytes in liver transplants: A rare event in sex-mismatched transplants. Hepatology 2002;36:173-176.
43. Thorgeirsson SS, Grisham JW. Hematopoietic cells as hepatocyte stem cells: A critical review of the evidence. Hepatology 2006;43:2-8.
44. Orkin SH, Zon LI. Hematopoiesis and stem cells; plasticity vs developmental heterogenity. Nature Immunol 2002;3:323-328.
45. Howell JC, Lee WH, Morrison P et al. Pluripotent stem cells identified in multiple murine tissue. Ann NY Acad Sci 2003;996:158-173.
46. Hung SC, Chen NJ, Hsieh SL et al. Isolation and characterization of side-sieved stem cells from human bone marrow. STEM CELLS 2002;20:249-258.
47. Ratajczak MZ, Kucia M, Reca R et al. Stem cell plasticity revisited: CXCR4-positive cells expressing mRNA for early muscle, liver and neural cells 'hide out' in the bone marrow. Leukemia 2004;18:29-40.
48. Kucia M, Ratajczak J, Ratajczak MZ. Bone marrow as source of circulating CXCR4+ tissue committed stem cells. Biol Cell 2005;97:133-146.
49. Kucia M, Reca R, Jala VR et al. Bone marrow as a home a heterogenous populations of nonhematopoietic stem cells. Leukemia 2005;19:1118-1127.
50. am Esch II JS, Knoefel WT, Klein M et al. Portal application of autologous CD133+ bone marrow cells to the liver-A novel concept to support hepatic regeneration. STEM CELLS 2005;23:463-470.
51. Gordon MY, Levicar N, Pai M et al. Characterization and clinical application of human CD34+ stem/progenitor cell populations mobilized into the blood by G-CSF. STEM CELLS 2006;24:1822-1830.
52. Baccarani U, De Stasio G, Adani GL et al. Implication of stem cell factor in human liver regeneration after transplantation and resection. Growth Factors 2006;24:107-110.