11,13-dihydro-dehydroleucodine, a derivative of dehydroleucodine with an inactivated alkylating function conserves the anti-proliferative activity in G2 but does not cause cytotoxicity

European Journal of Pharmacology

Volumn 556, Issue 1-3, 2007, Pages 19-26

  Polo, Luis M ^a   Castro, Claudia M ^b   Cruzado, Montserrat C ^c   Collino, César J G ^d   Cuello Carrión, F Darío ^b   Ciocca, Daniel R ^b   Giordano, Oscar S ^e   Ferrari, Monica ^e   López, Luis A ^a  

^a IHEM   (Argentina)

^b Facultad de Ciencias Naturales e Instituto M Lillo   (Argentina)

^c UNIVERSIDAD NACIONAL DE CUYO   (Argentina)

^d UNIVERSIDAD NACIONAL DE CÓRDOBA   (Argentina)

^e UNIVERSIDAD NACIONAL DE SAN LUIS   (Argentina)

Author keywords

11,13 dihydro dehydroleucodine; Anti proliferative activity; Cell cycle; Cytotoxicity; Dehydroleucodine; Sesquiterpene lactones

Indexed keywords

11,13 DIHYDRODEHYDROLEUCODINE; SESQUITERPENE LACTONE DERIVATIVE; UNCLASSIFIED DRUG;

ALKYLATION; ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL FUNCTION; CELL PROLIFERATION; CELL STIMULATION; CELL VIABILITY; CYTOTOXICITY; DNA REPLICATION; ENZYME ACTIVITY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SMOOTH MUSCLE FIBER;

ANIMALS; AORTA, THORACIC; APOPTOSIS; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; DNA REPLICATION; G2 PHASE; LACTONES; MALE; MUSCLE, SMOOTH; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; RATS; RATS, INBRED WKY; SESQUITERPENES;

EID: 33846066297     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2006.10.049     Document Type: Article

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