A novel activity for a group of sesquiterpene lactones: Inhibition of aromatase

FEBS Letters

Volumn 409, Issue 3, 1997, Pages 396-400

  Blanco, Javier G ^a   Gil, Roberto R ^a   Alvarez, Cecila I ^a   Patrito, Luis C ^a   Genti Raimondi, Susana ^a   Flury, Alfredo ^a  

^a UNIVERSIDAD NACIONAL DE CÓRDOBA   (Argentina)

Author keywords

Argentine; Aromatase inhibitor; Asteraceae; Cholesterol side chain cleavage; Human placental microsome; Sesquiterpene lactone; Type II ligand

Indexed keywords

AROMATASE; AROMATASE INHIBITOR; CHOLESTEROL MONOOXYGENASE (SIDE CHAIN CLEAVING); CYTOCHROME P450; GUAIANOLIDE DERIVATIVE; SESQUITERPENE LACTONE;

ARTICLE; COMPETITIVE INHIBITION; CONTROLLED STUDY; DOSE RESPONSE; DRUG ISOLATION; ENZYME ACTIVITY; ENZYME BINDING; ESTROGEN SYNTHESIS; FEMALE; HUMAN; HUMAN TISSUE; IN VITRO STUDY; MITOCHONDRION; PHYTOCHEMISTRY; PLACENTA; PRIORITY JOURNAL;

ANTI-ULCER AGENTS; AROMATASE INHIBITORS; CHOLESTEROL SIDE-CHAIN CLEAVAGE ENZYME; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; KINETICS; LACTONES; MICROSOMES; PREGNANCY PROTEINS; SESQUITERPENES; STRUCTURE-ACTIVITY RELATIONSHIP;

ARGENTINA (FISH); ASTERACEAE;

EID: 0030852023     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(97)00560-7     Document Type: Article

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