The plant pathogenesis related protein GLIPR-2 is highly expressed in fibrotic kidney and promotes epithelial to mesenchymal transition in vitro

Matrix Biology

Volumn 26, Issue 1, 2007, Pages 20-29

  Baxter, Ruth M ^a   Crowell, Thomas P ^a   George, Judith A ^a   Getman, Michael E ^a   Gardner, Humphrey ^a  

^a BIOGEN   (United States)

Author keywords

Epithelial mesenchymal transition (EMT); Fibrosis; GLIPR 2 GAPR 1; Myofibroblasts

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; ANTIBODY; BIOLOGICAL MARKER; GLIOMA PATHOGENESIS RELATED 2 PROTEIN; GOLGI ASSOCIATED PATHOGENESIS RELATED 1 PROTEIN; PROTEIN; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; KIDNEY EPITHELIUM; KIDNEY FIBROSIS; MOUSE; MYOFIBROBLAST; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; STAINING; UPREGULATION;

ACTINS; ANIMALS; AUTOANTIGENS; CADHERINS; CELL DIFFERENTIATION; CELL LINE; COLLAGEN TYPE IV; CONNECTIVE TISSUE CELLS; DISEASE MODELS, ANIMAL; EPITHELIAL CELLS; FIBROSIS; GENE EXPRESSION PROFILING; HUMANS; IMMUNOHISTOCHEMISTRY; KIDNEY; KIDNEY GLOMERULUS; KIDNEY MEDULLA; KIDNEY TUBULES; MEMBRANE PROTEINS; MICE; MICE, INBRED STRAINS; MICE, KNOCKOUT; PROTEINS; TRANSFECTION; VIMENTIN;

EID: 33846061090     PISSN: 0945053X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.matbio.2006.09.005     Document Type: Article

References (46)

1. Abe R., Donnelly S.C., Peng T., Bucala R., and Metz C.N. Peripheral blood fibrocytes: differentiation pathway and migration to wound sites. J. Immunol. 166 (2001) 7556-7562
2. Batlle E., Sancho E., Franci C., Dominguez D., Monfar M., Baulida J., and Garcia De Herreros A. The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells. Nat. Cell Biol. 2 (2000) 84-89
3. Bol J.F., and Linthorst H.J.M. Plant pathogenesis-related proteins induced by virus infection. Annu. Rev. Phytopathol. 28 (1990) 113-138
4. Cano A., Perez-Moreno M.A., Rodrigo I., Locascio A., Blanco M.J., del Barrio M.G., Portillo F., and Nieto M.A. The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression. Nat. Cell Biol. 2 (2000) 76-83
5. Chilosi M., Poletti V., Zamo A., Lestani M., Montagna L., Piccoli P., Pedron S., Bertaso M., Scarpa A., Murer B., Cancellieri A., Maestro R., Semenzato G., and Doglioni C. Aberrant Wnt/beta-catenin pathway activation in idiopathic pulmonary fibrosis. Am. J. Pathol. 162 (2003) 1495-1502
6. Cosgrove D., Rodgers K., Meehan D., Miller C., Bovard K., Gilroy A., Gardner H., Kotelianski V., Gotwals P., Amatucci A., and Kalluri R. Integrin alpha1beta1 and transforming growth factor-beta1 play distinct roles in alport glomerular pathogenesis and serve as dual targets for metabolic therapy. Am. J. Pathol. 157 (2000) 1649-1659
7. Desmouliere A. Factors influencing myofibroblast differentiation during wound healing and fibrosis. Cell Biol. Int. 19 (1995) 471-476
8. Desmouliere A., Badid C., Bochaton-Piallat M.L., and Gabbiani G. Apoptosis during wound healing, fibrocontractive diseases and vascular wall injury. Int. J. Biochem. Cell Biol. 29 (1997) 19-30
9. Desmouliere A., Darby I.A., and Gabbiani G. Normal and pathologic soft tissue remodeling: role of the myofibroblast, with special emphasis on liver and kidney fibrosis. Lab. Invest. 83 (2003) 1689-1707
10. Desmouliere A., Chaponnier C., and Gabbiani G. Tissue repair, contraction, and the myofibroblast. Wound Repair Regen. 13 (2005) 7-12
11. Durrant W.E., and Dong X. Systemic acquired resistance. Annu. Rev. Phytopathol. 42 (2004) 185-209
12. Eberle H.B., Serrano R.L., Fullekrug J., Schlosser A., Lehmann W.D., Lottspeich F., Kaloyanova D., Wieland F.T., and Helms J.B. Identification and characterization of a novel human plant pathogenesis-related protein that localizes to lipid-enriched microdomains in the Golgi complex. J. Cell Sci. 115 (2002) 827-838
13. Eisenberg I., Barash M., Kahan T., and Mitrani-Rosenbaum S. Cloning and characterization of a human novel gene C9orf19 encoding a conserved putative protein with an SCP-like extracellular protein domain. Gene 293 (2002) 141-148
14. Gabbiani G. The myofibroblast in wound healing and fibrocontractive diseases. J. Pathol. 200 (2003) 500-503
15. Gardner H., Shearstone J.R., Bandaru R., Crowell T., Lynes M., Trojanowska M., Pannu J., Smith E., Jablonska S., Blaszczyk M., Tan F.K., and Mayes M.D. Gene profiling of scleroderma skin reveals robust signatures of disease that are imperfectly reflected in the transcript profiles of explanted fibroblasts. Arthritis Rheum. 54 (2006) 1961-1973
16. Haverty T.P., Kelly C.J., Hines W.H., Amenta P.S., Watanabe M., Harper R.A., Kefalides N.A., and Neilson E.G. Characterization of a renal tubular epithelial cell line which secretes the autologous target antigen of autoimmune experimental interstitial nephritis. J. Cell Biol. 107 (1988) 1359-1368
17. Hinz B., and Gabbiani G. Mechanisms of force generation and transmission by myofibroblasts. Curr. Opin. Biotechnol. 14 (2003) 538-546
18. Hinz B., Celetta G., Tomasek J.J., Gabbiani G., and Chaponnier C. Alpha-smooth muscle actin expression upregulates fibroblast contractile activity. Mol. Biol. Cell 12 (2001) 2730-2741
19. Iwano M., and Neilson E.G. Mechanisms of tubulointerstitial fibrosis. Curr. Opin. Nephrol. Hypertens. 13 (2004) 279-284
20. Iwano M., Plieth D., Danoff T.M., Xue C., Okada H., and Neilson E.G. Evidence that fibroblasts derive from epithelium during tissue fibrosis. J. Clin. Invest. 110 (2002) 341-350
21. Kalluri R., and Neilson E.G. Epithelial-mesenchymal transition and its implications for fibrosis. J. Clin. Invest. 112 (2003) 1776-1784
22. Kasai H., Allen J.T., Mason R.M., Kamimura T., and Zhang Z. TGF-beta1 induces human alveolar epithelial to mesenchymal cell transition (EMT). Respir. Res. 6 (2005) 56
23. Klessig D.F., Durner J., Noad R., Navarre D.A., Wendehenne D., Kumar D., Zhou J.M., Shah J., Zhang S., Kachroo P., Trifa Y., Pontier D., Lam E., and Silva H. Nitric oxide and salicylic acid signaling in plant defense. Proc. Natl. Acad. Sci. U. S. A. 97 (2000) 8849-8855
24. Liu Y. Epithelial to mesenchymal transition in renal fibrogenesis: pathologic significance, molecular mechanism, and therapeutic intervention. J. Am. Soc. Nephrol. 15 (2004) 1-12
25. Lu G., Villalba M., Coscia M.R., Hoffman D.R., and King T.P. Sequence analysis and antigenic cross-reactivity of a venom allergen, antigen 5, from hornets, wasps, and yellow jackets. J. Immunol. 150 (1993) 2823-2830
26. Milne T.J., Abbenante G., Tyndall J.D.A., Halliday J., and Lewis R.J. Isolation and characterization of a cone snail protease with homology to the CRISP proteins of the pathogenesis-related protein superfamily. J. Biol. Chem. 278 (2003) 31105-31110
27. Mizuki N., and Kasahara M. Mouse submandibular glands express an androgen-regulated transcript encoding an acidic epididymal glycoprotein-like molecule. Mol. Cell. Endocrinol. 89 (1992) 25-32
28. Mori L., Bellini A., Stacey M.A., Schmidt M., and Mattoli S. Fibrocytes contribute to the myofibroblast population in wounded skin and originate from bone marrow. Exp. Cell Res. 304 (2005) 81-90
29. Murphy E.V., Zhang Y., Zhu W., and Biggs J. The human glioma pathogenesis-related protein is structurally related to plant pathogenesis-related proteins and is expressed specifically in brain tumors. Gene 159 (1995) 131-135
30. Niderman T., Genetet I., Bruyere T., Gees R., Stintzi A., Legrand M., Fritig B., and Mosinger E. Pathogenesis-related PR-1 proteins are antifungal. Plant Physiol. 108 (1995) 17-27
31. Okada H., Danoff T.M., Kalluri R., and Neilson E.G. Early role of Fsp1 in epithelial-mesenchymal transformation. Am. J. Physiol. 273 (1997) F563-F574
32. Peinado H., Marin F., Cubillo E., Stark H.J., Fusenig N., Nieto M.A., and Cano A. Snail and E47 repressors of E-cadherin induce distinct invasive and angiogenic properties in vivo. J. Cell Sci. 117 (2004) 2827-2839
33. Powell D.W., Mifflin R.C., Valentich J.D., Crowe S.E., Saada J.I., and West A.B. Myofibroblasts. I. Paracrine cells important in health and disease. Am. J. Physiol. 277 (1999) C1-C9
34. Quan T.E., Cowper S., Wu S.-P., Bockenstedt L.K., and Bucala R. Circulating fibrocytes: collagen-secreting cells of the peripheral blood. Int. J. Biochem. Cell Biol. 36 (2004) 598-606
35. Ren C., Li L., Yang G., Timme T.L., Goltsov A., Ren C., Ji X., Addai J., Luo H., Ittmann M.M., and Thompson T.C. RTVP-1, a tumor suppressor inactivated by methylation in prostate cancer. Cancer Res. 64 (2004) 969-976
36. Rich T., Chen P., Furman F., Huynh N., and Israel M.A. RTVP-1, a novel human gene with sequence similarity to genes of diverse species, is expressed in tumor cell lines of glial but not neuronal origin. Gene 180 (1996) 125-130
37. Sampson N.S., Ryan S.T., Enke D.A., Cosgrove D., Koteliansky V., and Gotwals P. Global gene expression analysis reveals a role for the alpha 1 integrin in renal pathogenesis. J. Biol. Chem. 276 (2001) 34182-34188
38. Schuren F.H., Asgeirsdottir S.A., Kothe E.M., Scheer J.M., and Wessels J.G. The Sc7/Sc14 gene family of Schizophyllum commune codes for extracellular proteins specifically expressed during fruit-body formation. J. Gen. Microbiol. 139 (1993) 2083-2090
39. Serini G., and Gabbiani G. Mechanisms of myofibroblast activity and phenotypic modulation. Exp. Cell Res. 250 (1999) 273-283
40. Strutz F., Okada H., Lo C.W., Danoff T., Carone R.L., Tomaszewski J.E., and Neilson E.G. Identification and characterization of a fibroblast marker: FSP1. J. Cell Biol. 130 (1995) 393-405
41. Szyperski T., Fernandez C., Mumenthaler C., and Wuthrich K. Structure comparison of human glioma pathogenesis-related protein GliPR and the plant pathogenesis-related protein P14a indicates a functional link between the human immune system and a plant defense system. Proc. Natl. Acad. Sci. U. S. A. 95 (1998) 2262-2266
42. Tomasek J.J., Gabbiani G., Hinz B., Chaponnier C., and Brown R.A. Myofibroblasts and mechano-regulation of connective tissue remodelling. Nat. Rev., Mol. Cell Biol. 3 (2002) 349-363
43. Van Loon L.C., and Van Kammen A. Polyacrylamide disc electrophoresis of the soluble leaf proteins from Nicotiana tabacum var. 'Samsun' and 'Samsun NN'. Virology 40 (1970) 199-211
44. Yang J., and Liu Y. Dissection of key events in tubular epithelial to myofibroblast transition and its implications in renal interstitial fibrosis. Am. J. Pathol. 159 (2001) 1465-1475
45. Zeisberg M., and Kalluri R. The role of epithelial-to-mesenchymal transition in renal fibrosis. J. Mol. Med. 82 (2004) 175-181
46. Zeisberg M., Bonner G., Maeshima Y., Colorado P., Muller G.A., Strutz F., and Kalluri R. Renal fibrosis: collagen composition and assembly regulates epithelial-mesenchymal transdifferentiation. Am. J. Pathol. 159 (2001) 1313-1321