-
1
-
-
33644657078
-
Inhalation therapy with metered-dose inhalers and dry powder inhalers in mechanically ventilated patients
-
discussion 1344-1335
-
Dhand R. Inhalation therapy with metered-dose inhalers and dry powder inhalers in mechanically ventilated patients. Respir Care 2005; 50:1331-1334; discussion 1344-1335.
-
(2005)
Respir Care
, vol.50
, pp. 1331-1334
-
-
Dhand, R.1
-
2
-
-
4644343918
-
Basic techniques for aerosol delivery during mechanical ventilation
-
Dhand R. Basic techniques for aerosol delivery during mechanical ventilation. Respir Care 2004; 49:611-622.
-
(2004)
Respir Care
, vol.49
, pp. 611-622
-
-
Dhand, R.1
-
3
-
-
21244459475
-
-
Vecellio L, Guerin C, Grimbert D, et al. In vitro study and semiempirical model for aerosol delivery control during mechanical ventilation. Intensive Care Med 2005; 31:871-876. These investigators determined the factors influencing drug delivery from a nebulizer in a bench model of mechanical ventilation. Once the drug output/minute was known, the time required to deliver a predetermined quantity of drug under the specified ventilatory conditions could be estimated.
-
Vecellio L, Guerin C, Grimbert D, et al. In vitro study and semiempirical model for aerosol delivery control during mechanical ventilation. Intensive Care Med 2005; 31:871-876. These investigators determined the factors influencing drug delivery from a nebulizer in a bench model of mechanical ventilation. Once the drug output/minute was known, the time required to deliver a predetermined quantity of drug under the specified ventilatory conditions could be estimated.
-
-
-
-
4
-
-
0344943933
-
Pulmonary drug delivery Part II: The role of inhalant delivery devices and drug formulations in therapeutic effectiveness of aerosolized medications
-
Labiris NR, Dolovich MB. Pulmonary drug delivery Part II: the role of inhalant delivery devices and drug formulations in therapeutic effectiveness of aerosolized medications. Br J Clin Pharmacol 2003; 56:600-612.
-
(2003)
Br J Clin Pharmacol
, vol.56
, pp. 600-612
-
-
Labiris, N.R.1
Dolovich, M.B.2
-
5
-
-
33846085198
-
-
Dhand R. Tobin M, editor. Bronchodilator therapy. 2nd ed. New York: McGraw Hill; 2006. This provides a comprehensive review of all aspects of inhaled bronchodilator therapy in mechanically ventilated patients.
-
Dhand R. Tobin M, editor. Bronchodilator therapy. 2nd ed. New York: McGraw Hill; 2006. This provides a comprehensive review of all aspects of inhaled bronchodilator therapy in mechanically ventilated patients.
-
-
-
-
6
-
-
0030845450
-
Inhaled bronchodilator therapy in mechanically ventilated patients
-
Dhand R, Tobin MJ. Inhaled bronchodilator therapy in mechanically ventilated patients. Am J Respir Crit Care Med 1997; 156:3-10.
-
(1997)
Am J Respir Crit Care Med
, vol.156
, pp. 3-10
-
-
Dhand, R.1
Tobin, M.J.2
-
7
-
-
0031739626
-
A comparison of inline MDI actuators for delivery of a beta agonist and a corticosteroid with a mechanically-ventilated lung model
-
Rau J, Dunlevy C, Hill P. A comparison of inline MDI actuators for delivery of a beta agonist and a corticosteroid with a mechanically-ventilated lung model. Respiratory Care 1998; 43:705-712.
-
(1998)
Respiratory Care
, vol.43
, pp. 705-712
-
-
Rau, J.1
Dunlevy, C.2
Hill, P.3
-
8
-
-
0032900977
-
Reconciling in vitro and in vivo measurements of aerosol delivery from a metered-dose inhaler during mechanical ventilation and defining efficiency-enhancing factors
-
Fink JB, Dhand R, Grychowski J, et al. Reconciling in vitro and in vivo measurements of aerosol delivery from a metered-dose inhaler during mechanical ventilation and defining efficiency-enhancing factors. Am J Respir Crit Care Med 1999; 159:63-68.
-
(1999)
Am J Respir Crit Care Med
, vol.159
, pp. 63-68
-
-
Fink, J.B.1
Dhand, R.2
Grychowski, J.3
-
9
-
-
0019377972
-
Deposition of pressurised aerosols in the human respiratory tract
-
Newman SP, Pavia D, Moren F, et al. Deposition of pressurised aerosols in the human respiratory tract. Thorax 1981; 36:52-55.
-
(1981)
Thorax
, vol.36
, pp. 52-55
-
-
Newman, S.P.1
Pavia, D.2
Moren, F.3
-
11
-
-
0242468642
-
Aerosol delivery and modern mechanical ventilation: In vitro/in vivo evaluation
-
Miller DD, Amin MM, Palmer LB, et al. Aerosol delivery and modern mechanical ventilation: in vitro/in vivo evaluation. Am J Respir Crit Care Med 2003; 168:1205-1209.
-
(2003)
Am J Respir Crit Care Med
, vol.168
, pp. 1205-1209
-
-
Miller, D.D.1
Amin, M.M.2
Palmer, L.B.3
-
12
-
-
0029781461
-
Dose-response to bronchodilator delivered by metered-dose inhaler in ventilator-supported patients
-
Dhand R, Duarte AG, Jubran A, et al. Dose-response to bronchodilator delivered by metered-dose inhaler in ventilator-supported patients. Am J Respir Crit Care Med 1996; 154:388-393.
-
(1996)
Am J Respir Crit Care Med
, vol.154
, pp. 388-393
-
-
Dhand, R.1
Duarte, A.G.2
Jubran, A.3
-
13
-
-
0034223152
-
Bronchodilator therapy with metered-dose inhaler and spacer versus nebulizer in mechanically ventilated patients: Comparison of magnitude and duration of response
-
Duarte AG, Momii K, Bidani A. Bronchodilator therapy with metered-dose inhaler and spacer versus nebulizer in mechanically ventilated patients: comparison of magnitude and duration of response. Respir Care 2000; 45:817-823.
-
(2000)
Respir Care
, vol.45
, pp. 817-823
-
-
Duarte, A.G.1
Momii, K.2
Bidani, A.3
-
14
-
-
0028337199
-
Nebulized ipratropium bromide in ventilator-assisted patients with chronic bronchitis
-
Yang SC, Yang SP, Lee TS. Nebulized ipratropium bromide in ventilator-assisted patients with chronic bronchitis. Chest 1994; 105:1511-1515.
-
(1994)
Chest
, vol.105
, pp. 1511-1515
-
-
Yang, S.C.1
Yang, S.P.2
Lee, T.S.3
-
15
-
-
0028231507
-
Comparison of one versus two bronchodilators in ventilated COPD patients
-
Fernandez A, Munoz J, de la Calle B, et al. Comparison of one versus two bronchodilators in ventilated COPD patients. Intensive Care Med 1994; 20:199-202.
-
(1994)
Intensive Care Med
, vol.20
, pp. 199-202
-
-
Fernandez, A.1
Munoz, J.2
de la Calle, B.3
-
16
-
-
23944439929
-
-
Tzoufi M, Mentzelopoulos SD, Roussos C, Armaganidis A. The effects of nebulized salbutamol, external positive end-expiratory pressure, and their combination on respiratory mechanics, hemodynamics, and gas exchange in mechanically ventilated chronic obstructive pulmonary disease patients. Anesth Analg 2005; 101:843-850. These investigators determined the effect of adding external positive end-expiratory pressure to inhaled albuterol on respiratory mechanics in stable mechanically-ventilated patients with COPD. Application of external PEEP, to counterbalance the effects of intrinsic PEEP, had additive effects to those observed after administration of albuterol.
-
Tzoufi M, Mentzelopoulos SD, Roussos C, Armaganidis A. The effects of nebulized salbutamol, external positive end-expiratory pressure, and their combination on respiratory mechanics, hemodynamics, and gas exchange in mechanically ventilated chronic obstructive pulmonary disease patients. Anesth Analg 2005; 101:843-850. These investigators determined the effect of adding external positive end-expiratory pressure to inhaled albuterol on respiratory mechanics in stable mechanically-ventilated patients with COPD. Application of external PEEP, to counterbalance the effects of intrinsic PEEP, had additive effects to those observed after administration of albuterol.
-
-
-
-
17
-
-
0027770791
-
Metered-dose inhaler versus nebulized albuterol in mechanically ventilated patients
-
Manthous CA, Hall JB, Schmidt GA, Wood LD. Metered-dose inhaler versus nebulized albuterol in mechanically ventilated patients. Am Rev Respir Dis 1993; 148:1567-1570.
-
(1993)
Am Rev Respir Dis
, vol.148
, pp. 1567-1570
-
-
Manthous, C.A.1
Hall, J.B.2
Schmidt, G.A.3
Wood, L.D.4
-
18
-
-
0034795340
-
Duration of salbutamol-induced bronchodilation delivered by metered-dose inhaler in mechanically ventilated COPD patients
-
Mouloudi E, Maliotakis C, Kondili E, et al. Duration of salbutamol-induced bronchodilation delivered by metered-dose inhaler in mechanically ventilated COPD patients. Monaldi Arch Chest Dis 2001; 56:189-194.
-
(2001)
Monaldi Arch Chest Dis
, vol.56
, pp. 189-194
-
-
Mouloudi, E.1
Maliotakis, C.2
Kondili, E.3
-
19
-
-
0028103867
-
Proximate delivery of a large experimental dose from salbutamol MDI induces epithelial airway lesions in intubated rabbits
-
Spahr-Schopfer IA, Lerman J, Cutz E, et al. Proximate delivery of a large experimental dose from salbutamol MDI induces epithelial airway lesions in intubated rabbits. Am J Respir Crit Care Med 1994; 150:790-794.
-
(1994)
Am J Respir Crit Care Med
, vol.150
, pp. 790-794
-
-
Spahr-Schopfer, I.A.1
Lerman, J.2
Cutz, E.3
-
20
-
-
0015505147
-
Cardiac toxicity of aerosol propellants
-
Silverglade A. Cardiac toxicity of aerosol propellants. Jama 1972; 222:827-828.
-
(1972)
Jama
, vol.222
, pp. 827-828
-
-
Silverglade, A.1
-
21
-
-
0025130061
-
Helium-oxygen mixtures in intubated patients with status asthmaticus and respiratory acidosis
-
Gluck EH, Onorato DJ, Castriotta R. Helium-oxygen mixtures in intubated patients with status asthmaticus and respiratory acidosis. Chest 1990; 98:693-698.
-
(1990)
Chest
, vol.98
, pp. 693-698
-
-
Gluck, E.H.1
Onorato, D.J.2
Castriotta, R.3
-
22
-
-
0035674507
-
Use of heliox in patients with severe exacerbation of chronic obstructive pulmonary disease
-
Gerbeaux P, Gainnier M, Boussuges A, et al. Use of heliox in patients with severe exacerbation of chronic obstructive pulmonary disease. Crit Care Med 2001; 29:2322-2324.
-
(2001)
Crit Care Med
, vol.29
, pp. 2322-2324
-
-
Gerbeaux, P.1
Gainnier, M.2
Boussuges, A.3
-
23
-
-
0033843250
-
Effects of helium-oxygen on intrinsic positive end-expiratory pressure in intubated and mechanically ventilated patients with severe chronic obstructive pulmonary disease
-
Tassaux D, Jolliet P, Roeseler J, Chevrolet JC. Effects of helium-oxygen on intrinsic positive end-expiratory pressure in intubated and mechanically ventilated patients with severe chronic obstructive pulmonary disease. Crit Care Med 2000; 28:2721-2728.
-
(2000)
Crit Care Med
, vol.28
, pp. 2721-2728
-
-
Tassaux, D.1
Jolliet, P.2
Roeseler, J.3
Chevrolet, J.C.4
-
24
-
-
18344377432
-
Heliox improves hemodynamics in mechanically ventilated patients with chronic obstructive pulmonary disease with systolic pressure variations
-
Lee DL, Lee H, Chang HW, et al. Heliox improves hemodynamics in mechanically ventilated patients with chronic obstructive pulmonary disease with systolic pressure variations. Crit Care Med 2005; 33:968-973.
-
(2005)
Crit Care Med
, vol.33
, pp. 968-973
-
-
Lee, D.L.1
Lee, H.2
Chang, H.W.3
-
25
-
-
0032755850
-
Beneficial effects of helium: Oxygen versus air:oxygen noninvasive pressure support in patients with decompensated chronic obstructive pulmonary disease
-
Jolliet P, Tassaux D, Thouret JM, Chevrolet JC. Beneficial effects of helium: oxygen versus air:oxygen noninvasive pressure support in patients with decompensated chronic obstructive pulmonary disease. Crit Care Med 1999; 27:2422-2429.
-
(1999)
Crit Care Med
, vol.27
, pp. 2422-2429
-
-
Jolliet, P.1
Tassaux, D.2
Thouret, J.M.3
Chevrolet, J.C.4
-
26
-
-
0032783823
-
Calibration of seven ICU ventilators for mechanical ventilation with helium-oxygen mixtures
-
Tassaux D, Jolliet P, Thouret JM, et al. Calibration of seven ICU ventilators for mechanical ventilation with helium-oxygen mixtures. Am J Respir Crit Care Med 1999; 160:22-32.
-
(1999)
Am J Respir Crit Care Med
, vol.160
, pp. 22-32
-
-
Tassaux, D.1
Jolliet, P.2
Thouret, J.M.3
-
27
-
-
0032913676
-
Effect of helium-oxygen on delivery of albuterol in a pediatric, volume-cycled, ventilated lung model
-
Habib DM, Garner SS, Brandeburg S. Effect of helium-oxygen on delivery of albuterol in a pediatric, volume-cycled, ventilated lung model. Pharmacotherapy 1999; 19:143-149.
-
(1999)
Pharmacotherapy
, vol.19
, pp. 143-149
-
-
Habib, D.M.1
Garner, S.S.2
Brandeburg, S.3
-
28
-
-
0035138503
-
Improvement in aerosol delivery with helium-oxygen mixtures during mechanical ventilation
-
Goode ML, Fink JB, Dhand R, Tobin MJ. Improvement in aerosol delivery with helium-oxygen mixtures during mechanical ventilation. Am J Respir Crit Care Med 2001; 163:109-114.
-
(2001)
Am J Respir Crit Care Med
, vol.163
, pp. 109-114
-
-
Goode, M.L.1
Fink, J.B.2
Dhand, R.3
Tobin, M.J.4
-
29
-
-
0032962998
-
The effect of heliox on nebulizer function using a beta-agonist bronchodilator
-
Hess DR, Acosta FL, Ritz RH, et al. The effect of heliox on nebulizer function using a beta-agonist bronchodilator. Chest 1999; 115:184-189.
-
(1999)
Chest
, vol.115
, pp. 184-189
-
-
Hess, D.R.1
Acosta, F.L.2
Ritz, R.H.3
-
30
-
-
0023264362
-
The effects of vasodilation with prostacyclin on oxygen delivery and uptake in critically ill patients
-
Bihari D, Smithies M, Gimson A, Tinker J. The effects of vasodilation with prostacyclin on oxygen delivery and uptake in critically ill patients. N Engl J Med 1987; 317:397-403.
-
(1987)
N Engl J Med
, vol.317
, pp. 397-403
-
-
Bihari, D.1
Smithies, M.2
Gimson, A.3
Tinker, J.4
-
31
-
-
0025058064
-
Prostacyclin for the treatment of pulmonary hypertension in the adult respiratory distress syndrome: Effects on pulmonary capillary pressure and ventilation-perfusion distributions
-
Radermacher P, Santak B, Wust HJ, et al. Prostacyclin for the treatment of pulmonary hypertension in the adult respiratory distress syndrome: effects on pulmonary capillary pressure and ventilation-perfusion distributions. Anesthesiology 1990; 72:238-244.
-
(1990)
Anesthesiology
, vol.72
, pp. 238-244
-
-
Radermacher, P.1
Santak, B.2
Wust, H.J.3
-
32
-
-
0031594797
-
Inhaled prostaglandin E1 for treatment of acute lung injury in severe multiple organ failure
-
Meyer J, Theilmeier G, Van Aken H, et al. Inhaled prostaglandin E1 for treatment of acute lung injury in severe multiple organ failure. Anesth Analg 1998; 86:753-758.
-
(1998)
Anesth Analg
, vol.86
, pp. 753-758
-
-
Meyer, J.1
Theilmeier, G.2
Van Aken, H.3
-
33
-
-
0031863568
-
Cardiopulmonary effects of aerosolized prostaglandin E1 and nitric oxide inhalation in patients with acute respiratory distress syndrome
-
Putensen C, Hormann C, Kleinsasser A, Putensen-Himmer G. Cardiopulmonary effects of aerosolized prostaglandin E1 and nitric oxide inhalation in patients with acute respiratory distress syndrome. Am J Respir Crit Care Med 1998; 157:1743-1747.
-
(1998)
Am J Respir Crit Care Med
, vol.157
, pp. 1743-1747
-
-
Putensen, C.1
Hormann, C.2
Kleinsasser, A.3
Putensen-Himmer, G.4
-
34
-
-
0029880173
-
Direct comparison of inhaled nitric oxide and aerosolized prostacyclin in acute respiratory distress syndrome
-
Walmrath D, Schneider T, Schermuly R, et al. Direct comparison of inhaled nitric oxide and aerosolized prostacyclin in acute respiratory distress syndrome. Am J Respir Crit Care Med 1996; 153:991-996.
-
(1996)
Am J Respir Crit Care Med
, vol.153
, pp. 991-996
-
-
Walmrath, D.1
Schneider, T.2
Schermuly, R.3
-
35
-
-
0030339154
-
Inhaled prostacyclin (PGI2) versus inhaled nitric oxide in adult respiratory distress syndrome
-
Zwissler B, Kemming G, Habler O, et al. Inhaled prostacyclin (PGI2) versus inhaled nitric oxide in adult respiratory distress syndrome. Am J Respir Crit Care Med 1996; 154:1671-1677.
-
(1996)
Am J Respir Crit Care Med
, vol.154
, pp. 1671-1677
-
-
Zwissler, B.1
Kemming, G.2
Habler, O.3
-
36
-
-
0028913446
-
Effects of aerosolized prostacyclin in severe pneumonia. Impact of fibrosis
-
Walmrath D, Schneider T, Pilch J, et al. Effects of aerosolized prostacyclin in severe pneumonia. Impact of fibrosis. Am J Respir Crit Care Med 1995; 151:724-730.
-
(1995)
Am J Respir Crit Care Med
, vol.151
, pp. 724-730
-
-
Walmrath, D.1
Schneider, T.2
Pilch, J.3
-
37
-
-
0034702248
-
Long-term treatment of primary pulmonary hypertension with aerosolized iloprost, a prostacyclin analogue
-
Hoeper MM, Schwarze M, Ehlerding S, et al. Long-term treatment of primary pulmonary hypertension with aerosolized iloprost, a prostacyclin analogue. N Engl J Med 2000; 342:1866-1870.
-
(2000)
N Engl J Med
, vol.342
, pp. 1866-1870
-
-
Hoeper, M.M.1
Schwarze, M.2
Ehlerding, S.3
-
38
-
-
0036682273
-
Inhaled iloprost for severe pulmonary hypertension
-
Olschewski H, Simonneau G, Galie N, et al. Inhaled iloprost for severe pulmonary hypertension. N Engl J Med 2002; 347:322-329.
-
(2002)
N Engl J Med
, vol.347
, pp. 322-329
-
-
Olschewski, H.1
Simonneau, G.2
Galie, N.3
-
39
-
-
1242329145
-
Hemodynamic response to sildenafil, nitric oxide, and iloprost in primary pulmonary hypertension
-
Leuchte HH, Schwaiblmair M, Baumgartner RA, et al. Hemodynamic response to sildenafil, nitric oxide, and iloprost in primary pulmonary hypertension. Chest 2004; 125:580-586.
-
(2004)
Chest
, vol.125
, pp. 580-586
-
-
Leuchte, H.H.1
Schwaiblmair, M.2
Baumgartner, R.A.3
-
40
-
-
0037006966
-
Combination therapy with oral sildenafil and inhaled iloprost for severe pulmonary hypertension
-
Ghofrani HA, Wiedemann R, Rose F, et al. Combination therapy with oral sildenafil and inhaled iloprost for severe pulmonary hypertension. Ann Intern Med 2002; 136:515-522.
-
(2002)
Ann Intern Med
, vol.136
, pp. 515-522
-
-
Ghofrani, H.A.1
Wiedemann, R.2
Rose, F.3
-
41
-
-
33644797883
-
-
Voswinckel R, Ghofrani HA, Grimminger F, et al. Inhaled treprostinil for treatment of chronic pulmonary arterial hypertension. Ann Intern Med 2006; 144:149-150. Administration of inhaled treprostinil (15mm) to three patients with severe pulmonary hypertension led to a significant reduction in pulmonary vascular resistance that was sustained for >180 min. In two patients inhlaed treprostinil (four doses of 15 μg each) were continued long-term with dramatic improvements in functional capacity.
-
Voswinckel R, Ghofrani HA, Grimminger F, et al. Inhaled treprostinil for treatment of chronic pulmonary arterial hypertension. Ann Intern Med 2006; 144:149-150. Administration of inhaled treprostinil (15mm) to three patients with severe pulmonary hypertension led to a significant reduction in pulmonary vascular resistance that was sustained for >180 min. In two patients inhlaed treprostinil (four doses of 15 μg each) were continued long-term with dramatic improvements in functional capacity.
-
-
-
-
42
-
-
0024335772
-
Pulmonary hypertension in acute respiratory failure
-
Villar J, Blazquez MA, Lubillo S, et al. Pulmonary hypertension in acute respiratory failure. Crit Care Med 1989; 17:523-526.
-
(1989)
Crit Care Med
, vol.17
, pp. 523-526
-
-
Villar, J.1
Blazquez, M.A.2
Lubillo, S.3
-
43
-
-
0027455571
-
Surfactant and the adult respiratory distress syndrome
-
Lewis JF, Jobe AH. Surfactant and the adult respiratory distress syndrome. Am Rev Respir Dis 1993; 147:218-233.
-
(1993)
Am Rev Respir Dis
, vol.147
, pp. 218-233
-
-
Lewis, J.F.1
Jobe, A.H.2
-
44
-
-
33747650519
-
Exogenous pulmonary surfactant for the treatment of adult patients with acute respiratory distress syndrome: Results of a meta-analysis
-
Davidson WJ, Dorscheid D, Spragg R, et al. Exogenous pulmonary surfactant for the treatment of adult patients with acute respiratory distress syndrome: results of a meta-analysis. Crit Care 2006; 10:R41.
-
(2006)
Crit Care
, vol.10
-
-
Davidson, W.J.1
Dorscheid, D.2
Spragg, R.3
-
45
-
-
0028128053
-
Acute effects of a single dose of porcine surfactant on patients with the adult respiratory distress syndrome
-
Spragg RG, Gilliard N, Richman P, et al. Acute effects of a single dose of porcine surfactant on patients with the adult respiratory distress syndrome. Chest 1994; 105:195-202.
-
(1994)
Chest
, vol.105
, pp. 195-202
-
-
Spragg, R.G.1
Gilliard, N.2
Richman, P.3
-
46
-
-
0030036989
-
Bronchoscopic surfactant administration in patients with severe adult respiratory distress syndrome and sepsis
-
Walmrath D, Gunther A, Ghofrani HA, et al. Bronchoscopic surfactant administration in patients with severe adult respiratory distress syndrome and sepsis. Am J Respir Crit Care Med 1996; 154:57-62.
-
(1996)
Am J Respir Crit Care Med
, vol.154
, pp. 57-62
-
-
Walmrath, D.1
Gunther, A.2
Ghofrani, H.A.3
-
47
-
-
0032831193
-
Bronchopulmonary segmental lavage with Surfaxin (KL(4)-surfactant) for acute respiratory distress syndrome
-
Wiswell TE, Smith RM, Katz LB, et al. Bronchopulmonary segmental lavage with Surfaxin (KL(4)-surfactant) for acute respiratory distress syndrome. Am J Respir Crit Care Med 1999; 160:1188-1195.
-
(1999)
Am J Respir Crit Care Med
, vol.160
, pp. 1188-1195
-
-
Wiswell, T.E.1
Smith, R.M.2
Katz, L.B.3
-
48
-
-
0037794407
-
Treatment of acute respiratory distress syndrome with recombinant surfactant protein C surfactant
-
Spragg RG, Lewis JF, Wurst W, et al. Treatment of acute respiratory distress syndrome with recombinant surfactant protein C surfactant. Am J Respir Crit Care Med 2003; 167:1562-1566.
-
(2003)
Am J Respir Crit Care Med
, vol.167
, pp. 1562-1566
-
-
Spragg, R.G.1
Lewis, J.F.2
Wurst, W.3
-
49
-
-
9344262898
-
Aerosolized surfactant in adults with sepsis-induced acute respiratory distress syndrome. Exosurf Acute Respiratory Distress Syndrome Sepsis Study Group
-
Anzueto A, Baughman RP, Guntupalli KK, et al. Aerosolized surfactant in adults with sepsis-induced acute respiratory distress syndrome. Exosurf Acute Respiratory Distress Syndrome Sepsis Study Group. N Engl J Med 1996; 334:1417-1421.
-
(1996)
N Engl J Med
, vol.334
, pp. 1417-1421
-
-
Anzueto, A.1
Baughman, R.P.2
Guntupalli, K.K.3
-
50
-
-
0028099647
-
Safety and potential efficacy of an aerosolized surfactant in human sepsis-induced adult respiratory distress syndrome
-
Weg JG, Balk RA, Tharratt RS, et al. Safety and potential efficacy of an aerosolized surfactant in human sepsis-induced adult respiratory distress syndrome. JAMA 1994; 272:1433-1438.
-
(1994)
JAMA
, vol.272
, pp. 1433-1438
-
-
Weg, J.G.1
Balk, R.A.2
Tharratt, R.S.3
-
51
-
-
0027270454
-
Physiologic responses and distribution of aerosolized surfactant (Survanta) in a nonuniform pattern of lung injury
-
Lewis JF, Ikegami M, Jobe AH, Absolom D. Physiologic responses and distribution of aerosolized surfactant (Survanta) in a nonuniform pattern of lung injury. Am Rev Respir Dis 1993; 147:1364-1370.
-
(1993)
Am Rev Respir Dis
, vol.147
, pp. 1364-1370
-
-
Lewis, J.F.1
Ikegami, M.2
Jobe, A.H.3
Absolom, D.4
-
52
-
-
4143067903
-
Effect of recombinant surfactant protein C-based surfactant on the acute respiratory distress syndrome
-
Spragg RG, Lewis JF, Walmrath HD, et al. Effect of recombinant surfactant protein C-based surfactant on the acute respiratory distress syndrome. N Engl J Med 2004; 351:884-892.
-
(2004)
N Engl J Med
, vol.351
, pp. 884-892
-
-
Spragg, R.G.1
Lewis, J.F.2
Walmrath, H.D.3
-
54
-
-
0032840712
-
Use of aerosolized antibiotics in patients with cystic fibrosis
-
Campbell III PW, Saiman L. Use of aerosolized antibiotics in patients with cystic fibrosis. Chest 1999; 116:775-788.
-
(1999)
Chest
, vol.116
, pp. 775-788
-
-
Campbell III, P.W.1
Saiman, L.2
-
55
-
-
0033531143
-
Intermittent administration of inhaled tobramycin in patients with cystic fibrosis. Cystic Fibrosis Inhaled Tobramycin Study Group
-
Ramsey BW, Pepe MS, Quan JM, et al. Intermittent administration of inhaled tobramycin in patients with cystic fibrosis. Cystic Fibrosis Inhaled Tobramycin Study Group. N Engl J Med 1999; 340:23-30.
-
(1999)
N Engl J Med
, vol.340
, pp. 23-30
-
-
Ramsey, B.W.1
Pepe, M.S.2
Quan, J.M.3
-
56
-
-
0016710474
-
Aerosol polymyxin and pneumonia in seriously ill patients
-
Feeley TW, Du Moulin GC, Hedley-Whyte J, et al. Aerosol polymyxin and pneumonia in seriously ill patients. N Engl J Med 1975; 293:471-475.
-
(1975)
N Engl J Med
, vol.293
, pp. 471-475
-
-
Feeley, T.W.1
Du Moulin, G.C.2
Hedley-Whyte, J.3
-
57
-
-
0031975321
-
Aerosolized antibiotics in mechanically ventilated patients: Delivery and response
-
Palmer LB, Smaldone GC, Simon SR, et al. Aerosolized antibiotics in mechanically ventilated patients: delivery and response. Crit Care Med 1998; 26:31-39.
-
(1998)
Crit Care Med
, vol.26
, pp. 31-39
-
-
Palmer, L.B.1
Smaldone, G.C.2
Simon, S.R.3
-
58
-
-
0033909658
-
Treatment of nosocomial pneumonia and tracheobronchitis caused by multidrug-resistant Pseudomonas aeruginosa with aerosolized colistin
-
Hamer DH. Treatment of nosocomial pneumonia and tracheobronchitis caused by multidrug-resistant Pseudomonas aeruginosa with aerosolized colistin. Am J Respir Crit Care Med 2000; 162:328-330.
-
(2000)
Am J Respir Crit Care Med
, vol.162
, pp. 328-330
-
-
Hamer, D.H.1
-
59
-
-
13844288106
-
Aerosolized colistin for the treatment of nosocomial pneumonia due to multidrug-resistant Gram-negative bacteria in patients without cystic fibrosis
-
Michalopoulos A, Kasiakou SK, Mastora Z, et al. Aerosolized colistin for the treatment of nosocomial pneumonia due to multidrug-resistant Gram-negative bacteria in patients without cystic fibrosis. Crit Care 2005; 9:R53-R59.
-
(2005)
Crit Care
, vol.9
-
-
Michalopoulos, A.1
Kasiakou, S.K.2
Mastora, Z.3
-
60
-
-
0036217521
-
Eradication of endotracheal tube biofilm by nebulised gentamicin
-
Adair CG, Gorman SP, Byers LM, et al. Eradication of endotracheal tube biofilm by nebulised gentamicin. Intensive Care Med 2002; 28:426-431.
-
(2002)
Intensive Care Med
, vol.28
, pp. 426-431
-
-
Adair, C.G.1
Gorman, S.P.2
Byers, L.M.3
-
61
-
-
0004946462
-
Implications of endotracheal tube biofilm for ventilator-associated pneumonia
-
Adair CG, Gorman SP, Feron BM, et al. Implications of endotracheal tube biofilm for ventilator-associated pneumonia. Intensive Care Med 1999; 25:1072-1076.
-
(1999)
Intensive Care Med
, vol.25
, pp. 1072-1076
-
-
Adair, C.G.1
Gorman, S.P.2
Feron, B.M.3
-
62
-
-
0025822596
-
A controlled trial of aerosolized ribavirin in infants receiving mechanical ventilation for severe respiratory syncytial virus infection
-
Smith DW, Frankel LR, Mathers LH, et al. A controlled trial of aerosolized ribavirin in infants receiving mechanical ventilation for severe respiratory syncytial virus infection. N Engl J Med 1991; 325:24-29.
-
(1991)
N Engl J Med
, vol.325
, pp. 24-29
-
-
Smith, D.W.1
Frankel, L.R.2
Mathers, L.H.3
-
63
-
-
0022339259
-
Effect of mucolytic and bronchodilator aerosol therapy on airway resistance in mechanically ventilated patients
-
Zandstra DF, Stoutenbeek CP, Miranda DR. Effect of mucolytic and bronchodilator aerosol therapy on airway resistance in mechanically ventilated patients. Intensive Care Med 1985; 11:316-318.
-
(1985)
Intensive Care Med
, vol.11
, pp. 316-318
-
-
Zandstra, D.F.1
Stoutenbeek, C.P.2
Miranda, D.R.3
-
64
-
-
0028923447
-
The effect of short-term instillation of a mucolytic agent (mesna) on airway resistance in mechanically ventilated patients
-
Fernandez R, Sole J, Blanch L, Artigas A. The effect of short-term instillation of a mucolytic agent (mesna) on airway resistance in mechanically ventilated patients. Chest 1995; 107:1101-1106.
-
(1995)
Chest
, vol.107
, pp. 1101-1106
-
-
Fernandez, R.1
Sole, J.2
Blanch, L.3
Artigas, A.4
-
65
-
-
0034763757
-
DNase treatment for atelectasis in infants with severe respiratory syncytial virus bronchiolitis
-
Merkus PJ, de Hoog M, van Gent R, de Jongste JC. DNase treatment for atelectasis in infants with severe respiratory syncytial virus bronchiolitis. Eur Respir J 2001; 18:734-737.
-
(2001)
Eur Respir J
, vol.18
, pp. 734-737
-
-
Merkus, P.J.1
de Hoog, M.2
van Gent, R.3
de Jongste, J.C.4
-
66
-
-
0032889636
-
Inhaled budesonide in ventilator-dependent preterm infants: A randomized, double-blind pilot study
-
Merz U, Kusenbach G, Hausler M, et al. Inhaled budesonide in ventilator-dependent preterm infants: a randomized, double-blind pilot study. Biol Neonate 1999; 75:46-53.
-
(1999)
Biol Neonate
, vol.75
, pp. 46-53
-
-
Merz, U.1
Kusenbach, G.2
Hausler, M.3
-
67
-
-
0033118991
-
Early inhaled glucocorticoid therapy to prevent bronchopulmonary dysplasia
-
Cole CH, Colton T, Shah BL, et al. Early inhaled glucocorticoid therapy to prevent bronchopulmonary dysplasia. N Engl J Med 1999; 340:1005-1010.
-
(1999)
N Engl J Med
, vol.340
, pp. 1005-1010
-
-
Cole, C.H.1
Colton, T.2
Shah, B.L.3
-
68
-
-
0028040181
-
Aerosol deposition in mechanically ventilated patients. Optimizing nebulizer delivery
-
O'Riordan TG, Palmer LB, Smaldone GC. Aerosol deposition in mechanically ventilated patients. Optimizing nebulizer delivery. Am J Respir Crit Care Med 1994; 149:214-219.
-
(1994)
Am J Respir Crit Care Med
, vol.149
, pp. 214-219
-
-
O'Riordan, T.G.1
Palmer, L.B.2
Smaldone, G.C.3
-
69
-
-
0029081287
-
Albuterol delivery in a model of mechanical ventilation: Comparison of metered-dose inhaler and nebulizer efficiency
-
Diot P, Morra L, Smaldone GC. Albuterol delivery in a model of mechanical ventilation: Comparison of metered-dose inhaler and nebulizer efficiency. Am J Respir Crit Care Med 1995; 152:1391-1394.
-
(1995)
Am J Respir Crit Care Med
, vol.152
, pp. 1391-1394
-
-
Diot, P.1
Morra, L.2
Smaldone, G.C.3
-
70
-
-
0026025256
-
Metered dose inhalers for bronchodilator delivery in intubated, mechanically ventilated patients
-
Gay PC, Patel HG, Nelson SB, et al. Metered dose inhalers for bronchodilator delivery in intubated, mechanically ventilated patients. Chest 1991; 99:66-71.
-
(1991)
Chest
, vol.99
, pp. 66-71
-
-
Gay, P.C.1
Patel, H.G.2
Nelson, S.B.3
-
71
-
-
0032938330
-
-
Guerin C, Chevre A, Dessirier P, et al. Inhaled fenoterol-ipratropium bromide in mechanically ventilated patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 1999; 159:1036-1042.
-
Guerin C, Chevre A, Dessirier P, et al. Inhaled fenoterol-ipratropium bromide in mechanically ventilated patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 1999; 159:1036-1042.
-
-
-
-
72
-
-
13544253826
-
-
Dolovich MB, Ahrens RC, Hess DR, et al. Device selection and outcomes of aerosol therapy: Evidence-based guidelines: American College of Chest Physicians/American College of Asthma, Allergy, and Immunology. Chest 2005; 127:335-371. Pertinent randomized controlled trials related to use of pMDIs, with or without spacer/holding chamber, versus dry powder inhalers versus nebulizers as delivery systems for β-agonists, anticholinergics, and corticosteroids in several commonly encountered clinical settings and patient populations were analyzed. Each of the delivery devices provided similar outcomes in patients using the correct technique of inhalation.
-
Dolovich MB, Ahrens RC, Hess DR, et al. Device selection and outcomes of aerosol therapy: Evidence-based guidelines: American College of Chest Physicians/American College of Asthma, Allergy, and Immunology. Chest 2005; 127:335-371. Pertinent randomized controlled trials related to use of pMDIs, with or without spacer/holding chamber, versus dry powder inhalers versus nebulizers as delivery systems for β-agonists, anticholinergics, and corticosteroids in several commonly encountered clinical settings and patient populations were analyzed. Each of the delivery devices provided similar outcomes in patients using the correct technique of inhalation.
-
-
-
-
74
-
-
0028113025
-
A comparison of commercial jet nebulizers
-
Loffert DT, Ikle D, Nelson HS. A comparison of commercial jet nebulizers. Chest 1994; 106:1788-1792.
-
(1994)
Chest
, vol.106
, pp. 1788-1792
-
-
Loffert, D.T.1
Ikle, D.2
Nelson, H.S.3
-
75
-
-
0029763316
-
Medication nebulizer performance. Effects of diluent volume, nebulizer flow, and nebulizer brand
-
Hess D, Fisher D, Williams P, et al. Medication nebulizer performance. Effects of diluent volume, nebulizer flow, and nebulizer brand. Chest 1996; 110:498-505.
-
(1996)
Chest
, vol.110
, pp. 498-505
-
-
Hess, D.1
Fisher, D.2
Williams, P.3
-
77
-
-
0041592702
-
In vitro evaluation of aerosol bronchodilator delivery during mechanical ventilation: Pressure-control vs volume control ventilation
-
Hess DR, Dillman C, Kacmarek RM. In vitro evaluation of aerosol bronchodilator delivery during mechanical ventilation: pressure-control vs volume control ventilation. Intensive Care Med 2003; 29:1145-1150.
-
(2003)
Intensive Care Med
, vol.29
, pp. 1145-1150
-
-
Hess, D.R.1
Dillman, C.2
Kacmarek, R.M.3
-
78
-
-
0021683471
-
Contaminated medication nebulizers in mechanical ventilator circuits. Source of bacterial aerosols
-
Craven DE, Lichtenberg DA, Goularte TA, et al. Contaminated medication nebulizers in mechanical ventilator circuits. Source of bacterial aerosols. Am J Med 1984; 77:834-838.
-
(1984)
Am J Med
, vol.77
, pp. 834-838
-
-
Craven, D.E.1
Lichtenberg, D.A.2
Goularte, T.A.3
-
79
-
-
0029023296
-
An outbreak of Burkholderia (formerly Pseudomonas) cepacia respiratory tract colonization and infection associated with nebulized albuterol therapy
-
Hamill RJ, Houston ED, Georghiou PR, et al. An outbreak of Burkholderia (formerly Pseudomonas) cepacia respiratory tract colonization and infection associated with nebulized albuterol therapy. Ann Intern Med 1995; 122:762-766.
-
(1995)
Ann Intern Med
, vol.122
, pp. 762-766
-
-
Hamill, R.J.1
Houston, E.D.2
Georghiou, P.R.3
-
80
-
-
0024352943
-
Continuous in-line nebulizers complicate pressure support ventilation
-
Beaty CD, Ritz RH, Benson MS. Continuous in-line nebulizers complicate pressure support ventilation. Chest 1989; 96:1360-1363.
-
(1989)
Chest
, vol.96
, pp. 1360-1363
-
-
Beaty, C.D.1
Ritz, R.H.2
Benson, M.S.3
-
81
-
-
0024563199
-
Aerosol bronchodilator delivery methods. Relative impact on pulmonary function and cost of respiratory care
-
Summer W, Elston R, Tharpe L, et al. Aerosol bronchodilator delivery methods. Relative impact on pulmonary function and cost of respiratory care. Arch Intern Med 1989; 149:618-623.
-
(1989)
Arch Intern Med
, vol.149
, pp. 618-623
-
-
Summer, W.1
Elston, R.2
Tharpe, L.3
-
82
-
-
0026543068
-
Substitution of metered-dose inhalers for hand-held nebulizers. Success and cost savings in a large, acute-care hospital
-
Bowton DL, Goldsmith WM, Haponik EF. Substitution of metered-dose inhalers for hand-held nebulizers. Success and cost savings in a large, acute-care hospital. Chest 1992; 101:305-308.
-
(1992)
Chest
, vol.101
, pp. 305-308
-
-
Bowton, D.L.1
Goldsmith, W.M.2
Haponik, E.F.3
-
83
-
-
0034049033
-
The distribution of costs of care in mechanically ventilated patients with chronic obstructive pulmonary disease
-
Ely EW, Baker AM, Evans GW, Haponik EF. The distribution of costs of care in mechanically ventilated patients with chronic obstructive pulmonary disease. Crit Care Med 2000; 28:408-413.
-
(2000)
Crit Care Med
, vol.28
, pp. 408-413
-
-
Ely, E.W.1
Baker, A.M.2
Evans, G.W.3
Haponik, E.F.4
-
84
-
-
0036134622
-
A survey of albuterol administration practices in intubated patients in the neonatal intensive care unit
-
Ballard J, Lugo RA, Salyer JW. A survey of albuterol administration practices in intubated patients in the neonatal intensive care unit. Respir Care 2002; 47:31-38.
-
(2002)
Respir Care
, vol.47
, pp. 31-38
-
-
Ballard, J.1
Lugo, R.A.2
Salyer, J.W.3
-
86
-
-
0029132818
-
Noninvasive ventilation for acute exacerbations of chronic obstructive pulmonary disease
-
Brochard L, Mancebo J, Wysocki M, et al. Noninvasive ventilation for acute exacerbations of chronic obstructive pulmonary disease. N Engl J Med 1995; 333:817-822.
-
(1995)
N Engl J Med
, vol.333
, pp. 817-822
-
-
Brochard, L.1
Mancebo, J.2
Wysocki, M.3
-
87
-
-
0027270409
-
Randomised controlled trial of nasal ventilation in acute ventilatory failure due to chronic obstructive airways disease
-
Bott J, Carroll MP, Conway JH, et al. Randomised controlled trial of nasal ventilation in acute ventilatory failure due to chronic obstructive airways disease. Lancet 1993; 341:1555-1557.
-
(1993)
Lancet
, vol.341
, pp. 1555-1557
-
-
Bott, J.1
Carroll, M.P.2
Conway, J.H.3
-
88
-
-
0029018269
-
Randomized, prospective trial of noninvasive positive pressure ventilation in acute respiratory failure
-
Kramer N, Meyer TJ, Meharg J, et al. Randomized, prospective trial of noninvasive positive pressure ventilation in acute respiratory failure. Am J Respir Crit Care Med 1995; 151:1799-1806.
-
(1995)
Am J Respir Crit Care Med
, vol.151
, pp. 1799-1806
-
-
Kramer, N.1
Meyer, T.J.2
Meharg, J.3
-
89
-
-
84923222206
-
Noninvasive positive pressure ventilation for treatment of respiratory failure due to exacerbations of chronic obstructive pulmonary disease
-
CD004104
-
Ram FS, Picot J, Lightowler J, Wedzicha JA. Noninvasive positive pressure ventilation for treatment of respiratory failure due to exacerbations of chronic obstructive pulmonary disease. Cochrane Database Syst Rev 2004; (3):CD004104.
-
(2004)
Cochrane Database Syst Rev
, Issue.3
-
-
Ram, F.S.1
Picot, J.2
Lightowler, J.3
Wedzicha, J.A.4
-
90
-
-
31944437927
-
Early noninvasive ventilation averts extubation failure in patients at risk: A randomized trial
-
Ferrer M, Valencia M, Nicolas JM, et al. Early noninvasive ventilation averts extubation failure in patients at risk: a randomized trial. Am J Respir Crit Care Med 2006; 173:164-170.
-
(2006)
Am J Respir Crit Care Med
, vol.173
, pp. 164-170
-
-
Ferrer, M.1
Valencia, M.2
Nicolas, J.M.3
-
91
-
-
0015899897
-
The fate of nebulized salbutamol (albuterol) administered by intermittent positive pressure respiration to asthmatic patients
-
Shenfield GM, Evans ME, Walker SR, Paterson JW. The fate of nebulized salbutamol (albuterol) administered by intermittent positive pressure respiration to asthmatic patients. Am Rev Respir Dis 1973; 108:501-505.
-
(1973)
Am Rev Respir Dis
, vol.108
, pp. 501-505
-
-
Shenfield, G.M.1
Evans, M.E.2
Walker, S.R.3
Paterson, J.W.4
-
92
-
-
0017362241
-
Pulmonary aerosol deposition in chronic bronchitis: Intermittent positive pressure breathing versus quiet breathing
-
Dolovich MB, Killian D, Wolff RK, et al. Pulmonary aerosol deposition in chronic bronchitis: intermittent positive pressure breathing versus quiet breathing. Am Rev Respir Dis 1977; 115:397-402.
-
(1977)
Am Rev Respir Dis
, vol.115
, pp. 397-402
-
-
Dolovich, M.B.1
Killian, D.2
Wolff, R.K.3
-
93
-
-
0031020173
-
Aerosol kinetics and bronchodilator efficacy during continuous positive airway pressure delivered by face mask
-
Parkes SN, Bersten AD. Aerosol kinetics and bronchodilator efficacy during continuous positive airway pressure delivered by face mask. Thorax 1997; 52:171-175.
-
(1997)
Thorax
, vol.52
, pp. 171-175
-
-
Parkes, S.N.1
Bersten, A.D.2
-
94
-
-
0036852058
-
In vitro evaluation of aerosol bronchodilator delivery during noninvasive positive pressure ventilation: Effect of ventilator settings and nebulizer position
-
Chatmongkolchart S, Schettino GP, Dillman C, et al. In vitro evaluation of aerosol bronchodilator delivery during noninvasive positive pressure ventilation: effect of ventilator settings and nebulizer position. Crit Care Med 2002; 30:2515-2519.
-
(2002)
Crit Care Med
, vol.30
, pp. 2515-2519
-
-
Chatmongkolchart, S.1
Schettino, G.P.2
Dillman, C.3
-
95
-
-
0034524326
-
Optimization of aerosol deposition by pressure support in children with cystic fibrosis: An experimental and clinical study
-
Fauroux B, Itti E, Pigeot J, et al. Optimization of aerosol deposition by pressure support in children with cystic fibrosis: an experimental and clinical study. Am J Respir Crit Care Med 2000; 162:2265-2271.
-
(2000)
Am J Respir Crit Care Med
, vol.162
, pp. 2265-2271
-
-
Fauroux, B.1
Itti, E.2
Pigeot, J.3
-
96
-
-
33644873498
-
-
Branconnier MP, Hess DR. Albuterol delivery during noninvasive ventilation. Respir Care 2005; 50:1649-1653. The effects of the site of the leak port in the circuit on drug delivery were tested in a bench model of non-invasive mechanical ventilation. With a nebulizer, more drug was delivered with the leak port in the circuit than in the mask. The position of the leak port did not influence drug delivery from a pMDI.
-
Branconnier MP, Hess DR. Albuterol delivery during noninvasive ventilation. Respir Care 2005; 50:1649-1653. The effects of the site of the leak port in the circuit on drug delivery were tested in a bench model of non-invasive mechanical ventilation. With a nebulizer, more drug was delivered with the leak port in the circuit than in the mask. The position of the leak port did not influence drug delivery from a pMDI.
-
-
-
-
97
-
-
0034764689
-
Salbutamol delivery during noninvasive mechanical ventilation in patients with chronic obstructive pulmonary disease: A randomized, controlled study
-
Nava S, Karakurt S, Rampulla C, et al. Salbutamol delivery during noninvasive mechanical ventilation in patients with chronic obstructive pulmonary disease: a randomized, controlled study. Intensive Care Med 2001; 27:1627-1635.
-
(2001)
Intensive Care Med
, vol.27
, pp. 1627-1635
-
-
Nava, S.1
Karakurt, S.2
Rampulla, C.3
-
98
-
-
0028842697
-
Treatment of acute bronchospasm with beta-adrenergic agonist aerosols delivered by a nasal bilevel positive airway pressure circuit
-
Pollack CV Jr, Fleisch KB, Dowsey K. Treatment of acute bronchospasm with beta-adrenergic agonist aerosols delivered by a nasal bilevel positive airway pressure circuit. Ann Emerg Med 1995; 26:552-557.
-
(1995)
Ann Emerg Med
, vol.26
, pp. 552-557
-
-
Pollack Jr, C.V.1
Fleisch, K.B.2
Dowsey, K.3
-
99
-
-
0037350202
-
Helium-oxygen versus air-oxygen noninvasive pressure support in decompensated chronic obstructive disease: A prospective, multicenter study
-
Jolliet P, Tassaux D, Roeseler J, et al. Helium-oxygen versus air-oxygen noninvasive pressure support in decompensated chronic obstructive disease: a prospective, multicenter study. Crit Care Med 2003; 31:878-884.
-
(2003)
Crit Care Med
, vol.31
, pp. 878-884
-
-
Jolliet, P.1
Tassaux, D.2
Roeseler, J.3
|