Cardiopulmonary effects of aerosolized prostaglandin E1 and nitric oxide inhalation in patients with acute respiratory distress syndrome

American Journal of Respiratory and Critical Care Medicine

Volumn 157, Issue 6 PART I, 1998, Pages 1743-1747

  Putensen, Christian ^a,b   Hörmann, Christoph ^a   Kleinsasser, Axel ^a   Putensen Himmer, Gabriele ^a  

^a UNIVERSITY OF INNSBRUCK   (Austria)

^b UNIVERSITY OF BONN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

NITRIC OXIDE; PROSTAGLANDIN E1;

ADULT; AGED; AIRWAY PRESSURE; ARTERIAL OXYGEN TENSION; ARTICLE; ARTIFICIAL VENTILATION; BURN; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFECT; FEMALE; GAS FLOW; HEART INDEX; HEART RIGHT VENTRICLE EJECTION FRACTION; HUMAN; INHALATIONAL DRUG ADMINISTRATION; LUNG GAS EXCHANGE; LUNG VASCULAR RESISTANCE; MALE; MULTIPLE TRAUMA; NEAR DROWNING; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RESPIRATORY DISTRESS SYNDROME; VASODILATATION;

EID: 0031863568     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/ajrccm.157.6.9609017     Document Type: Article

References (22)

1. Amato, M. B., C. S. Barbas, D. M. Medeiros, G. D. P. Schettino, G. Lorenzi-Filho, R. A. Kairalla, D. Deheinzelin, C. Morais, E. D. O. Fernandes, T. Y. Takagaki, and C. R. DeCarvalho. 1995. Beneficial effects of the "open lung approach" with low distending pressures in acute respiratory distress syndrome: a prospective randomized study on mechanical ventilation. Am. J. Respir. Crit. Care Med. 152:1835-1846.
2. Putensen, C., M. Baum, and C. Hörmann. 1993. Selecting ventilator settings according to variables derived from the quasi-static pressure/volume relationship in patients with acute lung injury. Anesth. Analg. 77:436-447.
3. Rossaint, R., K. J. Falke, F. Lopez, K. Slama, U. Pison, and W. M. Zapol. 1993. Inhaled nitric oxide for the adult respiratory distress syndrome. N. Engl. J. Med. 328:399-405.
4. Puybasset, L., J. J. Rouby, E. Mourgeon, T. E. Stewart, P. Cluzel, M. Arthaud, P. Poete, L. Bodin, A. M. Korinek, and P. Viars. 1994. Inhaled nitric oxide in acute respiratory failure: dose-response curves. Intensive Care Med. 20:319-327.
5. Radermacher, P., B. Santak, H. J. Wust, J. Tarnow, and K. J. Falke. 1990. Prostacyclin for the treatment of pulmonary hypertension in the adult respiratory distress syndrome: effects on pulmonary capillary pressure and ventilation-perfusion distributions. Anesthesiology 72:238-244.
6. 1 in the adult respiratory distress syndrome. Am. Rev. Respir. Dis. 139:106-110.
7. Walmrath, D., T. Schneider, R. Schermuly, H. Olschewski, F. Grimminger, and W. Seeger. 1996. Direct comparison of inhaled nitric oxide and aerosolized prostacyclin in acute respiratory distress syndrome. Am. J. Respir. Crit. Care Med. 153:991-996.
8. 1 during continuous intravenous infusion in patients with adult respiratory distress syndrome. Am. Rev. Respir. Dis. 137:5-12.
9. Piper, P. J., J. R. Vane, and J. H. Wyllie. 1970. Inactivation of prostaglandins by the lungs. Nature 225:600-604.
10. Bernard, G. R., A. Artigas, K. L. Brigham, J. Carlet, K. Falke, L. Hudson, M. Lamy, J. R. Le Gall, A. Morris, and R. Spragg. 1994. The American-European Consensus Conference on ARDS: definitions, mechanisms, relevant outcomes, and clinical trial coordination. Am. J. Respir. Crit. Care Med. 149:818-824.
11. Knaus, W. A., E. A. Draper, D. P. Wagner, and J. E. Zimmermann. 1985. Prognosis in acute organ system failure. Ann. Surg. 11:685-693.
12. Le Gall, J. R., P. Loirat, A. Alperovitch, P. Glaser, C. Granthil, D. Mathieu, P. Merceir, R. Thomas, and D. Villers. 1984. A simplified acute physiologic score for ICU patients. Crit. Care Med. 12:975-977.
13. Dhainaut, J. F., F. Brunet, J. F. Monsailier, D. Villemant, J. Y. Devaux, M. Konno, J. M. De Gournay, and J. J. Lanore. 1987. Bedside evaluation of right ventricular performance using a rapid computer thermodilution method. Crit. Care Med. 15:148-152.
14. Baydur, A., P. K. Behrakis, W. A. Zin, M. Jaeger, and J. Milic-Emili. 1982. A simple method for assessing the validity of the esophageal balloon technique. Am. Rev. Respir. Dis. 126:788-791.
15. Borok, Z., A. Gillissen, R. Buhl, R. F. Hoyt, R. C. Hubbard, T. Ozaki, S. I. Rennard, and R. G. Crystal. 1991. Augmentation of functional prostaglandin E levels on the respiratory epithelial surface by aerosol administration of prostaglandin E. Am. Rev. Respir. Dis. 144:1080-1084.
16. 1, isoproterenol, prostacyclin, and nifedipine in vasoconstrictor pulmonary hypertension in sheep. Anesth. Analg. 67:722-729.
17. Walmrath, D., T. Schneider, J. Pilch, R. Schermuly, F. Grimminger, and W. Seeger. 1995. Effects of aerosolized prostacyclin in severe pneumonia: impact of fibrosis. Am. J. Respir. Crit. Care Med. 151:724-730.
18. Eichelbrönner, O., H. Reinelt, H. Wiedeck, M. Mezödy, R. Rossaint, M. Georgieff, and P. Radermacher. 1996. Aerosolized prostacyclin and inhaled nitric oxide in septic shock - different effects on splanchnic oxygenation. Intensive Care Med. 22:880-887.
19. Rossaint, R., K. Slama, W. Steudel, H. Gerlach, D. Pappert, S. Veit, and K. Falke. 1995. Effects of inhaled nitric oxide on right ventricular function in severe acute respiratory distress syndrome. Intensive Care Med. 21:197-203.
20. Fierobe, L., F. Brunet, J. F. Dhainaut, M. Monchi, M. Belghith, J. P. Mira, J. Dall'ava-Santucci, and A. T. Dinh-Xuan. 1995. Effect of inhaled nitric oxide on right ventricular function in adult respiratory distress syndrome. Am. J. Respir. Crit. Care Med. 151:1414-1419.
21. Radermacher, P., B. Santak, H. J. Wust, J. Tarnow, and K. J. Falke. 1990. Prostacyclin and right ventricular function in patients with pulmonary hypertension associated with ARDS. Intensive Care Med. 16:227-232.
22. 1 and nitroglycerin reduce pulmonary capillary pressure but worsen ventilation-perfusion distributions in patients with adult respiratory distress syndrome. Anesthesiology 70:601-606.