Inhaled prostaglandin E1 for treatment of acute lung injury in severe multiple organ failure

Anesthesia and Analgesia

Volumn 86, Issue 4, 1998, Pages 753-758

  Meyer, Jörg ^a,b   Theilmeier, Gregor ^a   Van Aken, Hugo ^a   Bone, Hans Georg ^a   Busse, Heinz ^a   Waurick, René ^a   Hinder, Frank ^a   Booke, Michael ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

^b Klin Poliklin F A   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

PROSTAGLANDIN E1; NITRIC OXIDE; OXYGEN; PROSTACYCLIN; VASODILATOR AGENT;

ARTICLE; DATA ANALYSIS; DISEASE SEVERITY; HYPOXEMIA; LUNG ARTERY PRESSURE; LUNG VASOCONSTRICTION; LUNG VENTILATION; MEAN ARTERIAL PRESSURE; MULTIPLE ORGAN FAILURE; OXYGENATION; PRIORITY JOURNAL; PULMONARY HYPERTENSION; SURVIVAL RATE; ADULT; ADULT RESPIRATORY DISTRESS SYNDROME; AGED; APACHE; ARTIFICIAL VENTILATION; BLOOD; BLOOD PRESSURE; CENTRAL VENOUS PRESSURE; CONTROLLED CLINICAL TRIAL; DRUG EFFECT; FEMALE; HEART OUTPUT; HEART RATE; HUMAN; INHALATIONAL DRUG ADMINISTRATION; INTENSIVE CARE; LUNG; LUNG VENTILATION PERFUSION RATIO; LUNG WEDGE PRESSURE; MALE; MIDDLE AGED; NEBULIZER; OXYGEN CONSUMPTION; PROSPECTIVE STUDY; PULMONARY ARTERY; VASCULARIZATION;

ADMINISTRATION, INHALATION; ADULT; AGED; ALPROSTADIL; ANOXEMIA; APACHE; BLOOD PRESSURE; CARDIAC OUTPUT; CENTRAL VENOUS PRESSURE; CONTROLLED CLINICAL TRIALS; EPOPROSTENOL; FEMALE; HEART RATE; HUMANS; INTENSIVE CARE; LUNG; MALE; MIDDLE AGED; MULTIPLE ORGAN FAILURE; NEBULIZERS AND VAPORIZERS; NITRIC OXIDE; OXYGEN; OXYGEN CONSUMPTION; PROSPECTIVE STUDIES; PULMONARY ARTERY; PULMONARY WEDGE PRESSURE; RESPIRATION, ARTIFICIAL; RESPIRATORY DISTRESS SYNDROME, ADULT; SURVIVAL RATE; VASODILATOR AGENTS; VENTILATION-PERFUSION RATIO;

EID: 0031594797     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000539-199804000-00015     Document Type: Article

References (24)

1. Radermacher P, Santak B, Wust HJ, et al. Prostacyclin for the treatment of pulmonary hypertension in the adult respiratory distress syndrome: effects on pulmonary capillary pressure and ventilation-perfusion distributions. Anesthesiology 1990;72: 238-44.
2. Rossaint R, Falke KJ, Lopez F, et al. Inhaled nitric oxide for the adult respiratory distress syndrome. N Engl J Med 1993;328: 399-405.
3. Walmrath D, Schneider T, Pilch J, et al. Aerosolized prostacyclin in adult respiratory distress syndrome. Lancet 1993;342:961-2.
4. Wetzel RC. Aerosolized prostacyclin: in search of the ideal pulmonary vasodilator. Anesthesiology 1995;82:1315-7.
5. Zwissler B, Welte M, Messmer K. Inhalation of vasodilatory drugs or gases. Curr Opin Anaesthesiol 1995;8:557-64.
6. Booke M, Hinder M, Meyer J. Grenzen inhalativer Vasodilatatoren. Anaesthesist 1996;45:1097-107.
7. Zwissler B, Kemming G, Habler O, et al. Inhaled prostacyclin (PGI2) versus inhaled nitric oxide in adult respiratory distress syndrome. Am J Respir Crit Care Med 1996;154:1671-7.
8. Freeman B. Free radical chemistry of nitric oxide: looking at the dark side. Chest 1994;105:79S-84S.
9. Moncada S, Higgs EA. Metabolism of arachidonic acid. Ann N Y Acad Sci 1988;522:454-63.
10. 1 and nebulized prostacyclin. Appl Cardiovasc Pathophysiol 1997;6:233-9.
11. Roumen RM, Schers TJ, de Boer HH, Goris RJ. Scoring systems for predicting outcome in acute hemorrhagic necrotizing pancreatitis. Eur J Surg 1992;158:167-71.
12. Mikawa K, Akamatsu H, Maekawa N, et al. Inhibitory effect of prostaglandin E1 on human neutrophil function. Prostaglandins Leukot Essent Fatty Acids 1994;51:287-91.
13. 1 posttreatment decreases IL-1 alpha-induced neutrophil accumulation and lung leak in rats. J Appl Physiol 1994;76:151-7.
14. 1 and survival in patients with the adult respiratory distress syndrome: a prospective trial. Ann Surg 1986;203:371-8.
15. 1 Study Group. Chest 1989;96:114-9.
16. 1 induced deterioration of pulmonary gas exchange in COPD patients. Clin Physiol 1993;13:497-506.
17. 1 in acute respiratory distress syndrome: a placebo-controlled, randomized, double-blind, multicenter clinical trial. Crit Care Med 1996;24:10-5.
18. Smith WG, Thompson JM, Kowalski DL, McKearn JP. Inhaled misoprostol blocks guinea pig antigen-induced bronchoconstriction and airway inflammation. Am J Respir Crit Care Med 1996;154:295-9.
19. 1 during continuous intravenous infusion in patients with adult respiratory distress syndrome. Am Rev Respir Dis 1988;137:5-12.
20. 1 and 5-hydroxytryptamine removal in patients with adult respiratory distress syndrome. Am Rev Respir Dis 1986;134:739-44.
21. Gerlach H, Pappert D, Lewandowski K, et al. Long-term inhalation with evaluated low doses of nitric oxide for selective improvement of oxygenation in patients with adult respiratory distress syndrome. Intensive Care Med 1993;19:443-9.
22. Gerlach H, Rossaint R, Pappert D, Falke KJ. Time-course and dose-response of nitric oxide inhalation for systemic oxygenation and pulmonary hypertension in patients with adult respiratory distress syndrome. Eur J Clin Invest 1993;23:499-502.
23. Lundin S, Mang H, Smithies M, et al. Inhalation of nitric oxide in acute lung injury: preliminary results of a European multicenter study. Intensive Care Med 1997;23(Suppl 1):S2-6.
24. Rossaint R, Gerlach H, Schmidt Ruhnke H, et al. Efficacy of inhaled nitric oxide in patients with severe ARDS. Chest 1995; 107:1107-15.