Accumulation of oxidatively generated DNA damage in the brain: A mechanism of neurotoxicity

Free Radical Biology and Medicine

Volumn 42, Issue 3, 2007, Pages 385-393

  Chen, Liuji ^a,b   Lee, Heung M ^a,b   Greeley Jr , George H ^a   Englander, Ella W ^a,b  

^a University of Texas Medical Branch School of Medicine   (United States)

^b SHRINERS HOSPITALS FOR CHILDREN   (United States)

Author keywords

8 oxodG; APE1; Base excision repair; Brain; Combustion smoke inhalation; DNA repair fidelity; Malondialdehyde; Mismatched DNA bases; Neuronal injury; OGG1; Oxidative DNA lesions

Indexed keywords

BRAIN ENZYME; DNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BASE MISPAIRING; BRAIN TOXICITY; CONTROLLED STUDY; DNA ADDUCT; DNA DAMAGE; DNA STRAND BREAKAGE; EXPOSURE; GENE AMPLIFICATION; HIPPOCAMPUS; MISMATCH REPAIR; MUTAGENESIS; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATION KINETICS; OXIDATIVE STRESS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RAT; SMOKE;

ANIMALS; CELL DEATH; DNA ADDUCTS; DNA DAMAGE; HIPPOCAMPUS; LIPID PEROXIDATION; NERVE DEGENERATION; NEURONS; OXIDATION-REDUCTION; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; SMOKE INHALATION INJURY;

EID: 33845962112     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2006.11.009     Document Type: Article

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