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Volumn 61, Issue 12, 2006, Pages 1028-1033

Cytotoxicity of a newly synthesized nitroxide derivative of 4-ferrocenecarboxyl-2,2,6,6-tetramethylpiperidine-1-oxyl in high metastatic lung tumor cells

Author keywords

[No Author keywords available]

Indexed keywords

4 FERROCENECARBOXYL 2,2,6,6 TETRAMETHYLPIPERIDINE 1 OXYL; CASPASE 3; CASPASE 8; CASPASE INHIBITOR; CATALASE; NITROXIDE DERIVATIVE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

EID: 33845929615     PISSN: 00317144     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (12)

References (30)
  • 2
    • 0029911540 scopus 로고    scopus 로고
    • Spin label oximetry to assess extracellular oxygen during myocardial ischemia
    • Baker JE, Froncisz W, Joseph J, Kalyanaraman B (1997) Spin label oximetry to assess extracellular oxygen during myocardial ischemia. Free Radic Biol Med 22: 109-115.
    • (1997) Free Radic Biol Med , vol.22 , pp. 109-115
    • Baker, J.E.1    Froncisz, W.2    Joseph, J.3    Kalyanaraman, B.4
  • 3
    • 0020534380 scopus 로고    scopus 로고
    • Brasch RC, London DA, Wesbey GE, Tozer TN, Nitecki DE, Williams RD, Doemeny J, Tuck LD, Lallemand DP (1983) Work in progress: Nuclear magnetic resonance study of a paramagnetic nitroxide contrast agent for enhancement of renal structures in experimental animals. Radiology 147: 773-779.
    • Brasch RC, London DA, Wesbey GE, Tozer TN, Nitecki DE, Williams RD, Doemeny J, Tuck LD, Lallemand DP (1983) Work in progress: Nuclear magnetic resonance study of a paramagnetic nitroxide contrast agent for enhancement of renal structures in experimental animals. Radiology 147: 773-779.
  • 4
    • 0345222531 scopus 로고    scopus 로고
    • Mitochondrial function is differentially affected upon oxidative stress
    • Cardoso SM, Pereira C, Oliveira CR (1998) Mitochondrial function is differentially affected upon oxidative stress. Free Radic Biol Med 26: 3-13.
    • (1998) Free Radic Biol Med , vol.26 , pp. 3-13
    • Cardoso, S.M.1    Pereira, C.2    Oliveira, C.R.3
  • 5
    • 0034672470 scopus 로고    scopus 로고
    • Ganoderma extract activates MAP kinases and induces the neuronal differentiation of rat pheochromocytoma PC12 cells
    • Cheung WMW, Hui WS, Chu PWK, Chiu SW, Ip NY (2000) Ganoderma extract activates MAP kinases and induces the neuronal differentiation of rat pheochromocytoma PC12 cells. FEBS Lett 486: 291-296.
    • (2000) FEBS Lett , vol.486 , pp. 291-296
    • Cheung, W.M.W.1    Hui, W.S.2    Chu, P.W.K.3    Chiu, S.W.4    Ip, N.Y.5
  • 6
    • 0029619338 scopus 로고
    • Microplate superoxide dismutase assay employing a nonenzymatic superoxide generator
    • Ewing JF, Janero DR (1995) Microplate superoxide dismutase assay employing a nonenzymatic superoxide generator. Anal Biochem 232: 243-248.
    • (1995) Anal Biochem , vol.232 , pp. 243-248
    • Ewing, J.F.1    Janero, D.R.2
  • 7
    • 0032053876 scopus 로고    scopus 로고
    • Antiproliferative effect of the piperidine nitroxide tempol on neoplastic and nonneoplastic mammalian cellines
    • Gariboldi MB, Lucchi S, Caserini C, Supino R, Oliva C, Monti C (1998) Antiproliferative effect of the piperidine nitroxide tempol on neoplastic and nonneoplastic mammalian cellines. Free Radic Biol Med 24:913-923.
    • (1998) Free Radic Biol Med , vol.24 , pp. 913-923
    • Gariboldi, M.B.1    Lucchi, S.2    Caserini, C.3    Supino, R.4    Oliva, C.5    Monti, C.6
  • 8
    • 0033797023 scopus 로고    scopus 로고
    • The nitroxide tempol induces oxidative stress, p21WAF1/CIP1 and cell death in HL60 cells
    • Gariboldi MB, Rimoldi V, Supino R, Favini E, Monti E (2000) The nitroxide tempol induces oxidative stress, p21WAF1/CIP1 and cell death in HL60 cells. Free Radic Bio Med 29: 633-641.
    • (2000) Free Radic Bio Med , vol.29 , pp. 633-641
    • Gariboldi, M.B.1    Rimoldi, V.2    Supino, R.3    Favini, E.4    Monti, E.5
  • 9
    • 0037376807 scopus 로고    scopus 로고
    • Study of in vitro and in vivo effects of the piperidine nitroxide Tempol - A potential new therapeutic agent for gliomas
    • Gariboldi MB, Ravizza R, Petterino C, Castagnaro M, Finocchiaro G, Monti E (2003) Study of in vitro and in vivo effects of the piperidine nitroxide Tempol - A potential new therapeutic agent for gliomas. Eur J Cancer 39: 829-837.
    • (2003) Eur J Cancer , vol.39 , pp. 829-837
    • Gariboldi, M.B.1    Ravizza, R.2    Petterino, C.3    Castagnaro, M.4    Finocchiaro, G.5    Monti, E.6
  • 10
    • 0032127373 scopus 로고    scopus 로고
    • Mitochondrial membrane potential (DCmt) in the coordination of p53-independent proliferation and apoptosis pathways in human colonic carcinoma cells
    • Heerdt BG, Houston MA, Anthony GM, Augenlicht LH (1998) Mitochondrial membrane potential (DCmt) in the coordination of p53-independent proliferation and apoptosis pathways in human colonic carcinoma cells. Cancer Res 58: 2869-2875.
    • (1998) Cancer Res , vol.58 , pp. 2869-2875
    • Heerdt, B.G.1    Houston, M.A.2    Anthony, G.M.3    Augenlicht, L.H.4
  • 11
    • 0029826118 scopus 로고    scopus 로고
    • Prevention of hyperoxia-induced alterations in synaptosomal membrance-associated proteins by N-tert-butyl-alpha-phenylnitrone and 4-hydroxy-2,2,6,6,-tetramethylpiperidin-1-oxyl (TEMPOL)
    • Howard BJ, Yatin S, Hensley K, Allen KL, Kelly JP, Carney J, Butterfield DA (1996) Prevention of hyperoxia-induced alterations in synaptosomal membrance-associated proteins by N-tert-butyl-alpha-phenylnitrone and 4-hydroxy-2,2,6,6,-tetramethylpiperidin-1-oxyl (TEMPOL). J Neurochem 67: 2045-2050.
    • (1996) J Neurochem , vol.67 , pp. 2045-2050
    • Howard, B.J.1    Yatin, S.2    Hensley, K.3    Allen, K.L.4    Kelly, J.P.5    Carney, J.6    Butterfield, D.A.7
  • 12
    • 0034483321 scopus 로고    scopus 로고
    • Tempicol-3, a novel piperidine-N-oxide stable radical and antioxidant, with low toxicity acts as apoptosis inducer and cell proliferation modifier of Yoshida Sarcoma cells in vivo
    • Koceva-Chyla A, Kochman A, Glebska J, Gwoździnski K, Jóźwiak Z, Met́odiewa D (2000) Tempicol-3, a novel piperidine-N-oxide stable radical and antioxidant, with low toxicity acts as apoptosis inducer and cell proliferation modifier of Yoshida Sarcoma cells in vivo. Anticancer Res 20:4611-4618.
    • (2000) Anticancer Res , vol.20 , pp. 4611-4618
    • Koceva-Chyla, A.1    Kochman, A.2    Glebska, J.3    Gwoździnski, K.4    Jóźwiak, Z.5    Met́odiewa, D.6
  • 13
    • 0019216822 scopus 로고
    • ESR studies on membrane fluidity of Chinese hamster ovary cells grown on microcairiers and in suspension
    • Lai CS, Hopwood LE, Swartz HM (1980) ESR studies on membrane fluidity of Chinese hamster ovary cells grown on microcairiers and in suspension. Exp Cell Res 130: 437-442.
    • (1980) Exp Cell Res , vol.130 , pp. 437-442
    • Lai, C.S.1    Hopwood, L.E.2    Swartz, H.M.3
  • 14
    • 33845938229 scopus 로고    scopus 로고
    • Lan MB, Wu Y, Han J, Yuan HH (2005) Application and synthesis of a novel nitroxide derivative, 4-ferrocenecarboxyl-2,2,6,6-tetramethyl piperidine-1-oxyl (FC-TEMPO). China patent: CN 1709874
    • Lan MB, Wu Y, Han J, Yuan HH (2005) Application and synthesis of a novel nitroxide derivative, 4-ferrocenecarboxyl-2,2,6,6-tetramethyl piperidine-1-oxyl (FC-TEMPO). China patent: CN 1709874
  • 16
    • 0034011025 scopus 로고    scopus 로고
    • Hydrogen peroxide induces apoptosis in human hepatoma cells and alters cell redox status
    • Li J, Huang C-Y, Zheng R-L, Cui K-R, Li J-F (2000) Hydrogen peroxide induces apoptosis in human hepatoma cells and alters cell redox status. Cell Bio Int 24: 9-23.
    • (2000) Cell Bio Int , vol.24 , pp. 9-23
    • Li, J.1    Huang, C.-Y.2    Zheng, R.-L.3    Cui, K.-R.4    Li, J.-F.5
  • 17
    • 0027098146 scopus 로고
    • Transcutaneous absorption of nitroxide radicals detected in vivo by means of x-band ESR
    • Mader K, Stosser R, Borchert H-H (1992) Transcutaneous absorption of nitroxide radicals detected in vivo by means of x-band ESR. Pharmazie 47: 946-947
    • (1992) Pharmazie , vol.47 , pp. 946-947
    • Mader, K.1    Stosser, R.2    Borchert, H.-H.3
  • 18
    • 0033368329 scopus 로고    scopus 로고
    • Metexyl (4-methoxy-2,2,6,6-tetramethylpiperidine-1-oxyl) as an oxygen radicals scavenger and apoptosis inducer in vivo
    • Metodiewa D, Kochman A, Skolimowski J, Gebicka L, Koska C (1999) Metexyl (4-methoxy-2,2,6,6-tetramethylpiperidine-1-oxyl) as an oxygen radicals scavenger and apoptosis inducer in vivo. Anticancer Res 19: 5259-5264.
    • (1999) Anticancer Res , vol.19 , pp. 5259-5264
    • Metodiewa, D.1    Kochman, A.2    Skolimowski, J.3    Gebicka, L.4    Koska, C.5
  • 19
    • 0033855690 scopus 로고    scopus 로고
    • Evidence for peroxidative oxidation of substituted piperidine nitroxides, acting as apoptosis inducers in yoshida sarcoma cells in vivo
    • Metodiewa D, Kochman A, Gebicha L, Skolimowski A (2000) Evidence for peroxidative oxidation of substituted piperidine nitroxides, acting as apoptosis inducers in yoshida sarcoma cells in vivo. Anticancer Res 20: 2421-2426.
    • (2000) Anticancer Res , vol.20 , pp. 2421-2426
    • Metodiewa, D.1    Kochman, A.2    Gebicha, L.3    Skolimowski, A.4
  • 21
    • 0029788363 scopus 로고    scopus 로고
    • Protective effect of the nitroxide TEMPOL against the cardiotoxicity of adnamycin
    • Monti E, Cova D, Guido E, Morelli R, Oliva C (1996) Protective effect of the nitroxide TEMPOL against the cardiotoxicity of adnamycin. Free Radic Biol Med 21: 463-470.
    • (1996) Free Radic Biol Med , vol.21 , pp. 463-470
    • Monti, E.1    Cova, D.2    Guido, E.3    Morelli, R.4    Oliva, C.5
  • 24
    • 0025830445 scopus 로고
    • In the search for new anticancer drugs. XXIII: Exploration of a predictive design for anticancer drugs of carbohydrates containing N-ntirosochloroethylamino, N-nitrosomethyl, and N-nitrosoaminoxyl components
    • Sosnovsky G, Rao NUM (1991) In the search for new anticancer drugs. XXIII: exploration of a predictive design for anticancer drugs of carbohydrates containing N-ntirosochloroethylamino, N-nitrosomethyl, and N-nitrosoaminoxyl components. J Pharm Sci 80: 693-699.
    • (1991) J Pharm Sci , vol.80 , pp. 693-699
    • Sosnovsky, G.1    Rao, N.U.M.2
  • 25
    • 14744268278 scopus 로고    scopus 로고
    • Nitroxide tempo, a small molecule, induces apoptosis in prostate carcinoma cells and suppresses tumor growth in athymic mice
    • Suy S, Mitchell JB, Samuni A, Mueller S, Kasid U (2005) Nitroxide tempo, a small molecule, induces apoptosis in prostate carcinoma cells and suppresses tumor growth in athymic mice. Cancer 103: 1302-1313.
    • (2005) Cancer , vol.103 , pp. 1302-1313
    • Suy, S.1    Mitchell, J.B.2    Samuni, A.3    Mueller, S.4    Kasid, U.5
  • 26
    • 0031322560 scopus 로고    scopus 로고
    • DNA cleaving activity and cytotoxic activity of ferricenium cations
    • Tamura H, Miwa M (1997) DNA cleaving activity and cytotoxic activity of ferricenium cations. Chem Lett 11: 1177-1178.
    • (1997) Chem Lett , vol.11 , pp. 1177-1178
    • Tamura, H.1    Miwa, M.2
  • 27
    • 49449119325 scopus 로고
    • The preparation of ferrocenethiocarboxylic acid derivatives and their spectral properties
    • Tomonori K, Munehiro N, Shinzi K, Masateru M (1977) The preparation of ferrocenethiocarboxylic acid derivatives and their spectral properties. J Organometal Chem 129: 189-196.
    • (1977) J Organometal Chem , vol.129 , pp. 189-196
    • Tomonori, K.1    Munehiro, N.2    Shinzi, K.3    Masateru, M.4
  • 28
    • 0344876663 scopus 로고    scopus 로고
    • Synthesis, biochemical properties and molecular modelling studies of organometallic specific estrogen receptor modulators (SERMs), the ferrocifens and hydroxyferrocifens: Evidence for an antiproliferative effect of hydroxyferrocifens on both hormone-dependent and hormone-independent breast cancer cell lines
    • Top S, Vessières A, Leclercq G, Quivy J, Tang J, Vaissermann J, Huche M, Jaouen G (2003) Synthesis, biochemical properties and molecular modelling studies of organometallic specific estrogen receptor modulators (SERMs), the ferrocifens and hydroxyferrocifens: evidence for an antiproliferative effect of hydroxyferrocifens on both hormone-dependent and hormone-independent breast cancer cell lines. Chem Eur J 9: 5223-5236.
    • (2003) Chem Eur J , vol.9 , pp. 5223-5236
    • Top, S.1    Vessières, A.2    Leclercq, G.3    Quivy, J.4    Tang, J.5    Vaissermann, J.6    Huche, M.7    Jaouen, G.8
  • 29
    • 0006359442 scopus 로고    scopus 로고
    • Topoisomerase II poisoning and antineoplastic action by DNA-Nonbinding diacetyl and dicarboxaldoxime derivatives of ferrocene
    • Vashisht Gopal YN, Jayaraju D, Kondapi AK (2000) Topoisomerase II poisoning and antineoplastic action by DNA-Nonbinding diacetyl and dicarboxaldoxime derivatives of ferrocene. Arch Biochem Biophys 376: 229-235.
    • (2000) Arch Biochem Biophys , vol.376 , pp. 229-235
    • Vashisht Gopal, Y.N.1    Jayaraju, D.2    Kondapi, A.K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.