Nitroxide tempo, a small molecule, induces apoptosis in prostate carcinoma cells and suppresses tumor growth in athymic mice

Cancer

Volumn 103, Issue 6, 2005, Pages 1302-1313

  Suy, Simeng ^a   Mitchell, James B ^b   Samuni, Ayelet ^b   Mueller, Susette ^c   Kasid, Usha ^a  

^a GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c GEORGETOWN UNIVERSITY   (United States)

Author keywords

Antitumor effect; Apoptosis; Caspases; Cell cycle and cell proliferation; In vitro chemosensitization; Nitroxide tempo; Prostate carcinoma

Indexed keywords

ACTINOMYCIN DERIVATIVE; BROXURIDINE; CASPASE 3; CASPASE 9; CYCLOHEXIMIDE; CYSTEINE PROTEINASE; DNA; DOXORUBICIN; FLUORESCEIN ISOTHIOCYANATE; LIPOCORTIN 5; MITOXANTRONE; NITROXIDE DERIVATIVE; PIPERIDINE DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER COMBINATION CHEMOTHERAPY; CANCER INHIBITION; CELL CYCLE; CELL PROLIFERATION; CELL VIABILITY; CHEMOLUMINESCENCE; CHROMATIN ASSEMBLY AND DISASSEMBLY; CYTOTOXICITY; DRUG EFFICACY; DRUG POTENTIATION; ELECTRON MICROSCOPY; ENZYMATIC ASSAY; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; IMMUNOFLUORESCENCE TEST; MONOTHERAPY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROSTATE CARCINOMA; SIGNAL TRANSDUCTION; TUMOR CELL LINE; TUMOR GROWTH; TUMOR VOLUME;

ANALYSIS OF VARIANCE; ANIMALS; APOPTOSIS; BIOPSY, NEEDLE; CASPASE 3; CASPASES; CELL PROLIFERATION; CELL SURVIVAL; DISEASE MODELS, ANIMAL; IMMUNOHISTOCHEMISTRY; MALE; MICE; MICE, NUDE; MICROSCOPY, ELECTRON; PROBABILITY; PROSTATE; PROSTATIC NEOPLASMS; SENSITIVITY AND SPECIFICITY; TRIACETONEAMINE-N-OXYL; TUMOR CELLS, CULTURED;

EID: 14744268278     PISSN: 0008543X     EISSN: None     Source Type: Journal    
DOI: 10.1002/cncr.20898     Document Type: Article

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