Mitochondrial membrane potential (ΔΨ(mt)) in the coordination of p53- independent proliferation and apoptosis pathways in human colonic carcinoma cells

Cancer Research

Volumn 58, Issue 13, 1998, Pages 2869-2875

  Heerdt, Barbara G ^a,b   Houston, Michele A ^a   Anthony, Gillian M ^a   Augenlicht, Leonard H ^a  

^a ALBERT EINSTEIN CANCER CENTER   (United States)

^b MONTEFIORE MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P53;

APOPTOSIS; ARTICLE; CANCER CELL; CELL CULTURE; CELL PROLIFERATION; COLON CARCINOMA; FERMENTATION; GROWTH DISORDER; HUMAN; HUMAN CELL; MEMBRANE POTENTIAL; MITOCHONDRION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

APOPTOSIS; BUTYRIC ACID; BUTYRIC ACIDS; CELL AGGREGATION; CELL DIVISION; COLONIC NEOPLASMS; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLINS; CYTOCHROME C GROUP; FLOW CYTOMETRY; HUMANS; INTERPHASE; INTRACELLULAR MEMBRANES; MEMBRANE POTENTIALS; MITOCHONDRIA; ROTENONE; THENOYLTRIFLUOROACETONE; TUMOR CELLS, CULTURED; UNCOUPLING AGENTS;

EID: 0032127373     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (44)

1. Lipkin, M. Intermediate biomarkers of increased susceptibility to cancer of the large intestine. In: L. H. Augenlicht (ed.), Cell and Molecular Biology of Colon Cancer, pp. 97-109. Boca Raton, FL: CRC Press, 1989.
2. Bedi, A., Pasricha, P. J., Akhtar, A. J., Barber, J. P., Bedi, G. C., Giardiello, F. M., Zehnbauer, B. A., Hamilton, S. R., and Jones, R. J. Inhibition of apoptosis during development of colorectal cancer. Cancer Res., 55: 1811-1816, 1995.
3. Chang, W-C. L., Chapkin, R. S., and Lupton, J. R. Predictive value of proliferation, differentiation and apoptosis as intermediate markers for colon tumorigenesis. Carcinogenesis (Lond.), 18: 721-730, 1997.
4. Reddy, B. S., Wang, C. X., Samaha, H., Lubet, R., Steele, V. E., Kelloff, G. J., and Rao, C. V. Chemoprevention of colon carcinogenesis by dietary perillyl alcohol. Cancer Res., 57: 420-425, 1997.
5. Samaha, H. S., Kelloff, G. J., Steele, V. E., Rao, C. V., and Reddy, B. S. Modulation of apoptosis by sulindac, curcumin, phenylethyl-3-methylcaffeate, and 6-phenylhexyl isothiocyanate: apoptotic index as a biomarker in colonic cancer chemoprevention and promotion. Cancer Res., 57: 1301-1305, 1997.
6. Heerdt, B. G., Halsey, H. K., Lipkin, M., and Augenlicht, L. H. Expression of mitochondrial cytochrome c oxidase in human colonic cell differentiation, transformation, and risk for colonic cancer. Cancer Res., 50: 1596-1600, 1990.
7. Sun, A. S., Sepkowitz, K., and Beller, S. A. A study of some mitochondrial and peroxisomal enzymes in human colonic adenocarcinoma. Lab. Invest., 44: 13-17, 1981.
8. Summerhayes, I. C., Lampidis, T. J., Bernal, S. D., Nadakavukaren, J. J., Nadakavukaren, K. K., Shepherd, E. L., and Chen, L. B. Unusual retention of rhodamine 123 by mitochondria in muscle and carcinoma cells. Proc. Natl. Acad. Sci. USA, 79: 5292-5296, 1982.
9. Chen, L. B., and Rivers, E. N. Mitochondria in cancer cells. In: D. Carney and K. Sikora (eds.), Genes and Cancer, pp. 127-135. New York: John Wiley & Sons Inc., 1990.
10. Jacobson, M. D., Burne, J. F., and Raff, M. C. Programmed cell death and Bcl-2 protection in the absence of a nucleus. EMBO J., 13: 1899-1910, 1994.
11. Vayssiere, J-L., Petit, P. X., Risler, Y., and Mignotte, B. Commitment to apoptosis is associated with changes in mitochondrial biogenesis and activity in cell lines conditionally immortalized with simian virus 40. Proc. Natl. Acad. Sci. USA, 91: 11752-11756, 1994.
12. Zamzami, N., Susin, S. A., Marchetti, P., Hirsch, T., Gomez-Monterrey, I., Castedo, M., and Kroemer, G. Mitochondrial control of nuclear apoptosis. J. Exp. Med., 183: 1533-1544, 1996.
13. Marchetti, P., Castedo, M., Susin, S. A., Zamzami, N., Hirsch, T., Macho, A., Haeffner, A., Hirsch, F., Geuskens, M., and Kroemer, G. Mitochondrial permeability transition is a central coordinating event of apoptosis. J. Exp. Med., 184: 1155-1160, 1996.
14. Marchetti, P., Susin, S. A., Decaudin, D., Gamen, S., Castedo, M., Hirsch, T., Zamzami, N., Naval, J., Senik, A., and Kroemer, G. Apoptosis-associated derangement of mitochondrial function in cells lacking mitochondrial DNA. Cancer Res., 56: 2033-2038, 1996.
15. Hennet, T., Bertoni, G., Richter, C., and Peterhans, E. Expression of BCL-2 protein enhances the survival of mouse fibrosarcoid cells in tumor necrosis factor-mediated cytotoxicity. Cancer Res., 53: 1456-1460, 1993.
16. L antagonize the mitochondrial dysfunction pre-ceding nuclear apoptosis induced by chemotherapeutic agents. Cancer Res., 57: 62-67, 1997.
17. Heerdt, B. G., and Augenlicht, L. H. Effects of fatty acids on expression of genes encoding subunits of cytochrome c oxidase and cytochrome c oxidase activity in HT29 human colonic adenocarcinoma cells. J. Biol. Chem., 266: 19120-19126, 1991.
18. Heerdt, B. G., Houston, M. A., and Augenlicht, L. H. Potentiation by short-chain fatty acids of differentiation and apoptosis in human colonic carcinoma cell lines. Cancer Res., 54: 3288-3294, 1994.
19. Heerdt, B. G., Houston, M. A., and Augenlicht, L. H. Short-chain fatty acid initiated cell cycle arrest and apoptosis of colonic epithelial cells is linked to mitochondrial function. Cell Growth Differ., 8: 523-532, 1997.
20. Leibovitz, A., Stinson, J. C., McCombs, W. B., III, McCoy, C. E., Mazur, K. C., and Mabry, N. D. Classification of human colorectal adenocarcinoma cell lines. Cancer Res., 36: 4562-4569, 1976.
21. McGahon, A. J., Martin, S. J., Bissonnette, R. P., Mahboubi, A., Shi, Y., Mogil, R. J., Nishioka, W. K., and Green, D. R. The end of the (cell) line: methods for the study of apoptosis in vitro. In: L. M. Schwartz and B. A. Osborne (eds.), Cell Death, pp. 153-181. New York: Academic Press, 1995.
22. Bradford, M. M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principles of protein-dye binding. Ann. Biochem., 72: 248-254, 1976.
23. Linette, G. P., Li, Y., Roth, K., and Korsmeyer, S. J. Cross talk between cell death and cell cycle progression: BCL-2 regulates NFAT-mediated activation. Proc. Natl. Acad. Sci. USA, 93: 9545-9552, 1996.
24. Hueber, A-O., Zornig, M., Lyon, D., Suda, T., Nagata, S., and Evans, G. I. Requirement for the CD95 receptor-ligand pathway in c-Myc-induced apoptosis. Science (Washington DC), 278: 1305-1309, 1997.
25. Green, D. R. A myc-induced apoptosis pathway surfaces. Science (Washington DC), 278: 1246-1247, 1997.
26. Salvioli, S., Ardizzoni, A., Franceschi, C., and Cossarizza, A. JC-1, but not DiOC6(3) or rhodamine 123, is a reliable fluorescent probe to assess changes in intact cells: implications for studies on mitochondrial functionality during apoptosis. FEBS Lett., 411: 77-82, 1997.
27. Reers, M., Smith, T. W., and Chen, L. B. J-aggregate formation of a carbocyanine as a quantitative fluorescent indicator of membrane potential. Biochemistry, 30: 4480-4486, 1991.
28. Cossarizza, A., Baccarani-Contri, M., Kalashnikova, G., and Franceschi, C. A new method for the cytofluorimetric analysis of mitochondrial membrane potential using the J-aggregate forming lipophilic cation 5,5′6,6′-tetrachloro-1,1′3,3′-tetraethyl- benzimidazolcarbocyanine iodide (JC-1). Biochem. Biophys. Res. Commun., 30: 40-45, 1993.
29. Liu, X., Kim, C. N., Yang, J., Jemmerson, R., and Wang, X. Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c. Cell, 86: 147-157, 1996.
30. Liu, X., Zou, H., Slaughter, C., and Wang, X. DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis. Cell, 89: 175-184, 1997.
31. Zou, H., Hanzel, W. J., Liu, X., Lutschg, A., and Wang, X. Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3. Cell, 90: 405-413, 1997.
32. Fernandes-Alnemri, T., Litwick, G., and Alnemri, E. S. CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1-B-converting enzyme. J. Biol. Chem., 269: 30761-30764, 1994.
33. Tang, D. G., Li, L., Zhu, Z., and Joshi, B. Apoptosis in the absence of cytochrome c accumulation in the cytosol. Biochem. Biophys. Res. Commun., 242: 380-384, 1998.
34. Reed, J. C. Cytochrome c: can't live with it-can't live without it. Cell, 91: 559-562, 1997.
35. Kluck, R. M., Bossy-Wetzel, E., Green, D. R., and Newmeyer, D. D. The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis. Science (Washington DC), 275: 1132-1136, 1997.
36. Yang, J., Liu, X., Bhalla, K., Kim, C. N., Ibrado, A. M., Cai, Y., Peng, T-I., Jones, D. P., and Wang, X. Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria is blocked. Science (Washington DC), 275: 1129-1132, 1997.
37. Medina, V., Edmonds, B., Young, G. P., James, R., Appelton, S., and Zalewski, P. D. Induction of caspase-3 protease activity and apoptosis by butyrate and trichostatin A (inhibitors of histone deacetyiase): dependence on protein synthesis and synergy with mitochondrial cytochrome c-dependent pathway. Cancer Res., 57: 3697-3707, 1997.
38. 1 arrest and apoptosis. Cancer Res., 54: 1169-1174, 1994.
39. WAF1/Cip1 expression in normal and neoplastic tissues. Cancer Res., 55: 2910-2919, 1995.
40. Rodrigues, N. R., Rowan, A., Smith, M. E. F., Kerr, I. B., Bodmer, W. F., Gannon, J. V., and Lane, D. P. p53 mutations in colorectal cancer. Proc. Natl. Acad. Sci. USA, 87: 7555-7559, 1990.
41. Li, C-Y., Suardet, L., and Little, J. B. Potential role of WAF1/Cip1/p21 as a mediator of TGF-β cytoinhibitory effect. J. Biol. Chem., 270: 4971-4974, 1995.
42. Wang, C. Y., Eshleman, J. R., Wilson, J. K. V., and Markowitz, S. Both transforming growth factor-β and substrate release are inducers of apoptosis in a human colon adenoma cell line. Cancer Res., 55: 5101-5105, 1995.
43. WAF1/cip1 via C/EBPB. Nat. Med., 3: 1233-1241, 1997.
44. Siavoshian, S., Blottiere, H. M., Cherbut, C., and Galmiche, J-P. Butyrate stimulates cyclin D and p21 and inhibits cyclin-dependent kinase 2 expression in HT-29 colonic epithelial cells. Biochem. Biophys. Res. Commun., 232: 169-172, 1997.