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Volumn 6, Issue , 2006, Pages

Anti-vascular agent Combretastatin A-4-P modulates hypoxia inducible factor-1 and gene expression

Author keywords

[No Author keywords available]

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; COMBRETASTATIN A4 PHOSPHATE; FASUDIL; HYPOXIA INDUCIBLE FACTOR 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; VASCULAR TARGETING AGENT; VASCULOTROPIN A;

EID: 33845914327     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-6-280     Document Type: Article
Times cited : (34)

References (30)
  • 1
    • 0036984640 scopus 로고    scopus 로고
    • Role of angiogenesis in tumor growth and metastasis
    • Folkman J: Role of angiogenesis in tumor growth and metastasis. Semin Oncol 2002, 29(6 Suppl 16):15-8.
    • (2002) Semin Oncol , vol.29 , Issue.6 SUPPL. 16 , pp. 15-18
    • Folkman, J.1
  • 3
    • 0042887593 scopus 로고    scopus 로고
    • Assessment of pharmacodynamic vascular response in a phase I trial of combretastatin A4 phosphate
    • Anderson HL, Yap JT, Miller MP, Robbins A, Jones T, Price PM: Assessment of pharmacodynamic vascular response in a phase I trial of combretastatin A4 phosphate. J Clin Oncol 2003, 21(15):2823-30.
    • (2003) J Clin Oncol , vol.21 , Issue.15 , pp. 2823-2830
    • Anderson, H.L.1    Yap, J.T.2    Miller, M.P.3    Robbins, A.4    Jones, T.5    Price, P.M.6
  • 6
    • 4544277194 scopus 로고    scopus 로고
    • Combretastatin A4 phosphate: Background and current clinical status
    • Young SL, Chaplin DJ: Combretastatin A4 phosphate: background and current clinical status. Expert Opin Invest Drugs 2004, 13:1171-1182.
    • (2004) Expert Opin Invest Drugs , vol.13 , pp. 1171-1182
    • Young, S.L.1    Chaplin, D.J.2
  • 7
    • 0031980124 scopus 로고    scopus 로고
    • Antineoplastic agents 389. New syntheses of the combretastatin A-4 prodrug
    • Pettit GR, Rhodes MR: Antineoplastic agents 389. New syntheses of the combretastatin A-4 prodrug. Anticancer Drug Des 1998, 13(3):183-91.
    • (1998) Anticancer Drug Des , vol.13 , Issue.3 , pp. 183-191
    • Pettit, G.R.1    Rhodes, M.R.2
  • 8
    • 0035064594 scopus 로고    scopus 로고
    • Effects of combretastatin A4 phosphate on endothelial cell morphology in vitro and relationship to tumour vascular targeting activity in vivo
    • Galbraith SM, Chaplin DJ, Lee F, Stratford MR, Locke RJ, Vojnovic B, Tozer GM: Effects of combretastatin A4 phosphate on endothelial cell morphology in vitro and relationship to tumour vascular targeting activity in vivo. Anticancer Res 2001, 21(1A):93-102.
    • (2001) Anticancer Res , vol.21 , Issue.1 A , pp. 93-102
    • Galbraith, S.M.1    Chaplin, D.J.2    Lee, F.3    Stratford, M.R.4    Locke, R.J.5    Vojnovic, B.6    Tozer, G.M.7
  • 9
    • 0037085753 scopus 로고    scopus 로고
    • The tumor vascular targeting agent combretastatin A-4-phosphate induces reorganization of the actin cytoskeleton and early membrane blebbing in human endothelial cells
    • Kanthou C, Tozer GM: The tumor vascular targeting agent combretastatin A-4-phosphate induces reorganization of the actin cytoskeleton and early membrane blebbing in human endothelial cells. Blood 2002, 99(6):2060-9.
    • (2002) Blood , vol.99 , Issue.6 , pp. 2060-2069
    • Kanthou, C.1    Tozer, G.M.2
  • 11
    • 4644316617 scopus 로고    scopus 로고
    • The tubulin-binding agent combretastatin A-4-phosphate arrests endotheliall cells in mitosis and induces mitotic cell death
    • Kanthou C, Greco O, Stratford A, Cook I, Knight R, Benzakour O, Tozer G: The tubulin-binding agent combretastatin A-4-phosphate arrests endotheliall cells in mitosis and induces mitotic cell death. Am J Pathol 2004, 165(4):1401-11.
    • (2004) Am J Pathol , vol.165 , Issue.4 , pp. 1401-1411
    • Kanthou, C.1    Greco, O.2    Stratford, A.3    Cook, I.4    Knight, R.5    Benzakour, O.6    Tozer, G.7
  • 13
    • 0035417875 scopus 로고    scopus 로고
    • Mechanisms associated with tumor vascular shut-down induced by combretastatin A-4 phosphate: Intravital microscopy and measurement of vascular permeability
    • Tozer GM, Prise VE, Wilson J, Cemazar M, Shan S, Dewhirst MW, Barber PR, Vojnovic B, Chaplin DJ: Mechanisms associated with tumor vascular shut-down induced by combretastatin A-4 phosphate: intravital microscopy and measurement of vascular permeability. Cancer Res 2001, 61(17):6413-22.
    • (2001) Cancer Res , vol.61 , Issue.17 , pp. 6413-6422
    • Tozer, G.M.1    Prise, V.E.2    Wilson, J.3    Cemazar, M.4    Shan, S.5    Dewhirst, M.W.6    Barber, P.R.7    Vojnovic, B.8    Chaplin, D.J.9
  • 14
    • 0031770618 scopus 로고    scopus 로고
    • The effect of combretastatin A-4 disodium phosphate in a C3H mouse mammary carcinoma and a variety of murine spontaneous tumors
    • Horsman MR, Ehrnrooth E, Ladekari M, Overgaard J: The effect of combretastatin A-4 disodium phosphate in a C3H mouse mammary carcinoma and a variety of murine spontaneous tumors. Int J Radiat Oncol Biol Phys 1998, 42(4):895-8.
    • (1998) Int J Radiat Oncol Biol Phys , vol.42 , Issue.4 , pp. 895-898
    • Horsman, M.R.1    Ehrnrooth, E.2    Ladekari, M.3    Overgaard, J.4
  • 15
    • 14844325322 scopus 로고    scopus 로고
    • Tumour parameters affected by combretastatin A-4 phosphate therapy in a human colorectal xenograft model in nude mice
    • El-Emir E, Boxer GM, Petrie IA, Boden RW, Dearling JL, Begent RH, Pedley RB: Tumour parameters affected by combretastatin A-4 phosphate therapy in a human colorectal xenograft model in nude mice. Eur J Cancer 2005, 41(5):799-806.
    • (2005) Eur J Cancer , vol.41 , Issue.5 , pp. 799-806
    • El-Emir, E.1    Boxer, G.M.2    Petrie, I.A.3    Boden, R.W.4    Dearling, J.L.5    Begent, R.H.6    Pedley, R.B.7
  • 16
    • 0033867776 scopus 로고    scopus 로고
    • Hypoxia modulated gene expression: Angiogenesis, metastasis and therapeutic exploitation
    • (Spec No)
    • Dachs GU, Tozer GM: Hypoxia modulated gene expression: angiogenesis, metastasis and therapeutic exploitation. Eur J Cancer 2000, 36(13 Spec No): 1649-60.
    • (2000) Eur J Cancer , vol.36 , Issue.13 , pp. 1649-1660
    • Dachs, G.U.1    Tozer, G.M.2
  • 17
    • 0030951899 scopus 로고    scopus 로고
    • Combretastatin A-4, an agent that displays potent and selective toxicity toward tumor vasculature
    • Dark GG, Hill SA, Prise VE, Tozer GM, Pettit GR, Chaplin DJ: Combretastatin A-4, an agent that displays potent and selective toxicity toward tumor vasculature. Cancer Res 1997, 57(10):1829-34.
    • (1997) Cancer Res , vol.57 , Issue.10 , pp. 1829-1834
    • Dark, G.G.1    Hill, S.A.2    Prise, V.E.3    Tozer, G.M.4    Pettit, G.R.5    Chaplin, D.J.6
  • 18
    • 0037326037 scopus 로고    scopus 로고
    • The von Hippel-Lindau tumor suppressor, hypoida-inducible factor-1 (HIF-1) degradation, and cancer pathogenesis
    • Pugh CW, Ratcliffe PJ: The von Hippel-Lindau tumor suppressor, hypoida-inducible factor-1 (HIF-1) degradation, and cancer pathogenesis. Semin Cancer Biol 2003, 13(1):83-9.
    • (2003) Semin Cancer Biol , vol.13 , Issue.1 , pp. 83-89
    • Pugh, C.W.1    Ratcliffe, P.J.2
  • 20
    • 85047695603 scopus 로고    scopus 로고
    • Cell density mediated pericellular hypoxia leads to induction of HIF-1alpha via nitric oxide and Ras/MAP kinase mediated signaling pathways
    • Sheta EA, Trout H, Gildea JJ, Harding MA, Theodorescu D: Cell density mediated pericellular hypoxia leads to induction of HIF-1alpha via nitric oxide and Ras/MAP kinase mediated signaling pathways. Oncogene 2001, 20(52):7624-34.
    • (2001) Oncogene , vol.20 , Issue.52 , pp. 7624-7634
    • Sheta, E.A.1    Trout, H.2    Gildea, J.J.3    Harding, M.A.4    Theodorescu, D.5
  • 21
    • 0027136260 scopus 로고
    • Desferrioxamine induces erythropoietin gene expression and hypoxia-inducible factor 1 DNA-binding activity: Implications for models of hypoxia signal transduction
    • Wang GL, Semenza GL: Desferrioxamine induces erythropoietin gene expression and hypoxia-inducible factor 1 DNA-binding activity: implications for models of hypoxia signal transduction. Blood 1993, 82(12):3610-5.
    • (1993) Blood , vol.82 , Issue.12 , pp. 3610-3615
    • Wang, G.L.1    Semenza, G.L.2
  • 22
    • 0036282385 scopus 로고    scopus 로고
    • The biology of the combretastatins as tumour vascular targeting agents
    • Tozer GM, Kanthou C, Parkins CS, Hill SA: The biology of the combretastatins as tumour vascular targeting agents. Int J Exp Pathol 2002, 83(1):21-38.
    • (2002) Int J Exp Pathol , vol.83 , Issue.1 , pp. 21-38
    • Tozer, G.M.1    Kanthou, C.2    Parkins, C.S.3    Hill, S.A.4
  • 23
    • 0032538797 scopus 로고    scopus 로고
    • Signal transduction in hypoxic cells: Inducible nuclear translocation and recruitment of the CBP/p300 coactivator by the hypoxia-inducible factor-1α
    • Kallio PJ, Okamoto K, O'Brien S, Carrero P, Makino Y, Tanaka H, Poellinger L: Signal transduction in hypoxic cells: Inducible nuclear translocation and recruitment of the CBP/p300 coactivator by the hypoxia-inducible factor-1α EMBO J 1998, 17(22):6573-86.
    • (1998) EMBO J , vol.17 , Issue.22 , pp. 6573-6586
    • Kallio, P.J.1    Okamoto, K.2    O'Brien, S.3    Carrero, P.4    Makino, Y.5    Tanaka, H.6    Poellinger, L.7
  • 24
    • 0642307227 scopus 로고    scopus 로고
    • Phase I trial of the antivascular agent combretastatin A-4 phosphate on a 5-day schedule to patients with cancer: Magnetic resonance imaging evidence for altered tumor blood flow
    • Stevenson JP, Rosen M, Sun W, Gallagher M, Haller DG, Vaughn D, Giantonio B, Zimmer R, Petros WP, Stratford M, Chaplin D, Young SL, et al.: Phase I trial of the antivascular agent combretastatin A-4 phosphate on a 5-day schedule to patients with cancer: magnetic resonance imaging evidence for altered tumor blood flow. J Clin Oncol 2003, 21(23):4428-38.
    • (2003) J Clin Oncol , vol.21 , Issue.23 , pp. 4338-4428
    • Stevenson, J.P.1    Rosen, M.2    Sun, W.3    Gallagher, M.4    Haller, D.G.5    Vaughn, D.6    Giantonio, B.7    Zimmer, R.8    Petros, W.P.9    Stratford, M.10    Chaplin, D.11    Young, S.L.12
  • 25
    • 0031020884 scopus 로고    scopus 로고
    • Endothelial PAS domain protein I (EPASI), a transcription factor selectively expressed in endothelial cells
    • Tian H, McKnight SL, Russell DW: Endothelial PAS domain protein I (EPASI), a transcription factor selectively expressed in endothelial cells. Genes Dev 1997, 11(1):72-82.
    • (1997) Genes Dev , vol.11 , Issue.1 , pp. 72-82
    • Tian, H.1    McKnight, S.L.2    Russell, D.W.3
  • 26
    • 0141988698 scopus 로고    scopus 로고
    • Predominant role of hypoxia-inducible transcription factor (Hif)1alpha versus Hif-2alpha in regulation of the transcriptional response to hypoxia
    • Sowter HM, Raval RR, Moore JW, Ratcliffe PJ, Harris AL: Predominant role of hypoxia-inducible transcription factor (Hif)1alpha versus Hif-2alpha in regulation of the transcriptional response to hypoxia. Cancer Res 2003, 63(19):6130-4.
    • (2003) Cancer Res , vol.63 , Issue.19 , pp. 6130-6134
    • Sowter, H.M.1    Raval, R.R.2    Moore, J.W.3    Ratcliffe, P.J.4    Harris, A.L.5
  • 27
    • 0037470172 scopus 로고    scopus 로고
    • Microtubule disruption utilizes an NFκB-dependent pathway to stabilize HIF-1α protein
    • Jung YJ, Isaacs JS, Lee S, Trepel J, Neckers L: Microtubule disruption utilizes an NFκB-dependent pathway to stabilize HIF-1α protein. J Biol Chem 2003, 278(9):7445-52.
    • (2003) J Biol Chem , vol.278 , Issue.9 , pp. 7445-7452
    • Jung, Y.J.1    Isaacs, J.S.2    Lee, S.3    Trepel, J.4    Neckers, L.5
  • 28
    • 9144268981 scopus 로고    scopus 로고
    • RhoA/Rho-associated kinase pathway selectively regulates thrombin-induced intercellular adhesion molecule-1 expression in endothelial cells via activation of 1 kappa B kinase beta and phosphorylation of ReIA/p65
    • Anwar KN, Fazal F, Malik AB, Rahman A. RhoA/Rho-associated kinase pathway selectively regulates thrombin-induced intercellular adhesion molecule-1 expression in endothelial cells via activation of 1 kappa B kinase beta and phosphorylation of ReIA/p65. J Immunol 2004, 173(11):6965-72.
    • (2004) J Immunol , vol.173 , Issue.11 , pp. 6965-6972
    • Anwar, K.N.1    Fazal, F.2    Malik, A.B.3    Rahman, A.4
  • 29
    • 3843090808 scopus 로고    scopus 로고
    • Combretastatin family member OX14503 induces tumor vascular collapse through the induction of endothelial apoptosis
    • Sheng Y, Hua J, Pinney KG, Garner CM, Kane RR, Prezioso JA, Chaplin DJ, Edvardsen K: Combretastatin family member OX14503 induces tumor vascular collapse through the induction of endothelial apoptosis Int J Cancer 2004, 111(4):604-10.
    • (2004) Int J Cancer , vol.111 , Issue.4 , pp. 604-610
    • Sheng, Y.1    Hua, J.2    Pinney, K.G.3    Garner, C.M.4    Kane, R.R.5    Prezioso, J.A.6    Chaplin, D.J.7    Edvardsen, K.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.