-
1
-
-
0037233327
-
Survivin and apoptosis control
-
Altieri DC (2003a) Survivin and apoptosis control. Adv Cancer Res 88:31-52.
-
(2003)
Adv Cancer Res
, vol.88
, pp. 31-52
-
-
Altieri, D.C.1
-
2
-
-
0037267333
-
Validating survivin as a cancer therapeutic target
-
Altieri DC (2003b) Validating survivin as a cancer therapeutic target. Nat Rev Cancer 3:46-54.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 46-54
-
-
Altieri, D.C.1
-
3
-
-
28244490602
-
Survivin expression is regulated by coexpression of human epidermal growth factor receptor 2 and epidermal growth factor receptor via phosphatidylinositol 3-kinase/AKT signaling pathway in breast cancer cells
-
Asanuma H, Torigoe T, Kamiguchi K, Hirohashi Y, Ohmura T, Hirata K, Sato M, and Sato N (2005) Survivin expression is regulated by coexpression of human epidermal growth factor receptor 2 and epidermal growth factor receptor via phosphatidylinositol 3-kinase/AKT signaling pathway in breast cancer cells. Cancer Res 65:11018-11025.
-
(2005)
Cancer Res
, vol.65
, pp. 11018-11025
-
-
Asanuma, H.1
Torigoe, T.2
Kamiguchi, K.3
Hirohashi, Y.4
Ohmura, T.5
Hirata, K.6
Sato, M.7
Sato, N.8
-
4
-
-
0033637762
-
Survivin as a radioresistance factor in pancreatic cancer
-
Asanuma K, Moriai R, Yajima T, Yagihashi A, Yamada M, Kobayashi D, and Watanabe N (2000) Survivin as a radioresistance factor in pancreatic cancer. Jpn J Cancer Res 91:1204-1209.
-
(2000)
Jpn J Cancer Res
, vol.91
, pp. 1204-1209
-
-
Asanuma, K.1
Moriai, R.2
Yajima, T.3
Yagihashi, A.4
Yamada, M.5
Kobayashi, D.6
Watanabe, N.7
-
5
-
-
27744432361
-
Cisplatin activates Akt in small cell lung cancer cells and attenuates apoptosis by survivin upregulation
-
Belyanskaya LL, Hopkins-Donaldson S, Kurtz S, Simoes-Wust AP, Yousefi S, Simon HU, Stahel R, and Zangemeister-Wittke U (2005) Cisplatin activates Akt in small cell lung cancer cells and attenuates apoptosis by survivin upregulation. Int J Cancer 117:755-763.
-
(2005)
Int J Cancer
, vol.117
, pp. 755-763
-
-
Belyanskaya, L.L.1
Hopkins-Donaldson, S.2
Kurtz, S.3
Simoes-Wust, A.P.4
Yousefi, S.5
Simon, H.U.6
Stahel, R.7
Zangemeister-Wittke, U.8
-
6
-
-
0037453909
-
Effects of deguelin on the phosphatidylinositol 3-kinase/Akt pathway and apoptosis in premalignant human bronchial epithelial cells
-
Chun KH, Kosmeder JW 2nd, Sun S, Pezzuto JM, Lotan R, Hong WK, and Lee HY (2003) Effects of deguelin on the phosphatidylinositol 3-kinase/Akt pathway and apoptosis in premalignant human bronchial epithelial cells. J Natl Cancer Inst 95:291-302.
-
(2003)
J Natl Cancer Inst
, vol.95
, pp. 291-302
-
-
Chun, K.H.1
Kosmeder, J.W.2
Sun, S.3
Pezzuto, J.M.4
Lotan, R.5
Hong, W.K.6
Lee, H.Y.7
-
7
-
-
1242317030
-
Akt phosphorylation and stabilization of X-linked inhibitor of apoptosis protein (XIAP)
-
Dan HC, Sun M, Kaneko S, Feldman RI, Nicosia SV, Wang HG, Tsang BK, and Cheng JQ (2004) Akt phosphorylation and stabilization of X-linked inhibitor of apoptosis protein (XIAP). J Biol Chem 279:5405-5412.
-
(2004)
J Biol Chem
, vol.279
, pp. 5405-5412
-
-
Dan, H.C.1
Sun, M.2
Kaneko, S.3
Feldman, R.I.4
Nicosia, S.V.5
Wang, H.G.6
Tsang, B.K.7
Cheng, J.Q.8
-
8
-
-
0033082995
-
IAP family proteins-suppressors of apoptosis
-
Deveraux QL and Reed JC (1999) IAP family proteins-suppressors of apoptosis. Genes Dev 13:239-252.
-
(1999)
Genes Dev
, vol.13
, pp. 239-252
-
-
Deveraux, Q.L.1
Reed, J.C.2
-
9
-
-
4544261227
-
An IAP-IAP complex inhibits apoptosis
-
Dohi T, Okada K, Xia F, Wilford CE, Samuel T, Welsh K, Marusawa H, Zou H, Armstrong R, Matsuzawa S, et al. (2004) An IAP-IAP complex inhibits apoptosis. J Biol Chem 279:34087-34090.
-
(2004)
J Biol Chem
, vol.279
, pp. 34087-34090
-
-
Dohi, T.1
Okada, K.2
Xia, F.3
Wilford, C.E.4
Samuel, T.5
Welsh, K.6
Marusawa, H.7
Zou, H.8
Armstrong, R.9
Matsuzawa, S.10
-
10
-
-
17844368327
-
The MAPK signalling pathways and colorectal cancer
-
Fang JY and Richardson BC (2005) The MAPK signalling pathways and colorectal cancer. Lancet Oncol 6:322-327.
-
(2005)
Lancet Oncol
, vol.6
, pp. 322-327
-
-
Fang, J.Y.1
Richardson, B.C.2
-
11
-
-
28544443984
-
Promoting apoptosis as a strategy for cancer drug discovery
-
Fesik SW (2005) Promoting apoptosis as a strategy for cancer drug discovery. Nat Rev Cancer 5:876-885.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 876-885
-
-
Fesik, S.W.1
-
12
-
-
0034841661
-
Phosphoinositide 3-kinase signalling in breast cancer: How big a role might it play?
-
Fry MJ (2001) Phosphoinositide 3-kinase signalling in breast cancer: how big a role might it play? Breast Cancer Res 3:304-312.
-
(2001)
Breast Cancer Res
, vol.3
, pp. 304-312
-
-
Fry, M.J.1
-
13
-
-
0041859233
-
Regulation of ornithine decarboxylase induction by deguelin, a natural product cancer chemopreventive agent
-
Gerhauser C, Lee SK, Kosmeder JW, Moriarty RM, Hamel E, Mehta RG, Moon RC, and Pezzuto JM (1997) Regulation of ornithine decarboxylase induction by deguelin, a natural product cancer chemopreventive agent. Cancer Res 57:3429-3435.
-
(1997)
Cancer Res
, vol.57
, pp. 3429-3435
-
-
Gerhauser, C.1
Lee, S.K.2
Kosmeder, J.W.3
Moriarty, R.M.4
Hamel, E.5
Mehta, R.G.6
Moon, R.C.7
Pezzuto, J.M.8
-
14
-
-
2442669734
-
Apoptosis induction by the natural product cancer chemopreventive agent deguelin is mediated through the inhibition of mitochondrial bioenergetics
-
Hail N Jr and Lotan R (2004) Apoptosis induction by the natural product cancer chemopreventive agent deguelin is mediated through the inhibition of mitochondrial bioenergetics. Apoptosis 9:437-447.
-
(2004)
Apoptosis
, vol.9
, pp. 437-447
-
-
Hail Jr, N.1
Lotan, R.2
-
15
-
-
0034905394
-
XIAP: Apoptotic brake and promising therapeutic target
-
Holcik M, Gibson H, and Korneluk RG (2001) XIAP: apoptotic brake and promising therapeutic target. Apoptosis 6:253-261.
-
(2001)
Apoptosis
, vol.6
, pp. 253-261
-
-
Holcik, M.1
Gibson, H.2
Korneluk, R.G.3
-
16
-
-
0035831022
-
Structural basis of caspase inhibition by XIAP: Differential roles of the linker versus the BIR domain
-
Huang Y, Park YC, Rich RL, Segal D, Myszka DG, and Wu H (2001) Structural basis of caspase inhibition by XIAP: differential roles of the linker versus the BIR domain. Cell 104:781-790.
-
(2001)
Cell
, vol.104
, pp. 781-790
-
-
Huang, Y.1
Park, Y.C.2
Rich, R.L.3
Segal, D.4
Myszka, D.G.5
Wu, H.6
-
17
-
-
0035008874
-
-
Hutchinson J, Jin J, Cardiff RD, Woodgett JR, and Muller WJ (2001) Activation of Akt (protein kinase B) in mammary epithelium provides a critical cell survival signal required for tumor progression. Mol Cell Biol 21:2203-2212.
-
Hutchinson J, Jin J, Cardiff RD, Woodgett JR, and Muller WJ (2001) Activation of Akt (protein kinase B) in mammary epithelium provides a critical cell survival signal required for tumor progression. Mol Cell Biol 21:2203-2212.
-
-
-
-
18
-
-
0036547417
-
Death and anti-death: Tumour resistance to apoptosis
-
Igney FH and Krammer PH (2002) Death and anti-death: tumour resistance to apoptosis. Nat Rev Cancer 2:277-288.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 277-288
-
-
Igney, F.H.1
Krammer, P.H.2
-
19
-
-
0036725957
-
Quantitative analysis of expression levels of bax, bcl-2, and survivin in cancer cells during cisplatin treatment
-
Ikeguchi M, Nakamura S, and Kaibara N (2002) Quantitative analysis of expression levels of bax, bcl-2, and survivin in cancer cells during cisplatin treatment. Oncol Rep 9:1121-1126.
-
(2002)
Oncol Rep
, vol.9
, pp. 1121-1126
-
-
Ikeguchi, M.1
Nakamura, S.2
Kaibara, N.3
-
20
-
-
4143078350
-
Molecular mechanisms of deguelin-induced apoptosis in transformed human bronchial epithelial cells
-
Lee HY (2004) Molecular mechanisms of deguelin-induced apoptosis in transformed human bronchial epithelial cells. Biochem Pharmacol 68:1119-1124.
-
(2004)
Biochem Pharmacol
, vol.68
, pp. 1119-1124
-
-
Lee, H.Y.1
-
21
-
-
27944452718
-
Chemopreventive effects of deguelin, a novel Akt inhibitor, on tobacco-induced lung tumorigenesis
-
Lee HY, Oh SH, Woo JK, Kim WY, Van Pelt CS, Price RE, Cody D, Tran H, Pezzuto JM, Moriarty RM, et al. (2005) Chemopreventive effects of deguelin, a novel Akt inhibitor, on tobacco-induced lung tumorigenesis. J Natl Cancer Inst 97:1695-1699.
-
(2005)
J Natl Cancer Inst
, vol.97
, pp. 1695-1699
-
-
Lee, H.Y.1
Oh, S.H.2
Woo, J.K.3
Kim, W.Y.4
Van Pelt, C.S.5
Price, R.E.6
Cody, D.7
Tran, H.8
Pezzuto, J.M.9
Moriarty, R.M.10
-
22
-
-
0032506524
-
-
F, Ambrosini G, Chu EY, Plescia J, Tognin S, Marchisio PC, and Altieri DC (1998) Control of apoptosis and mitotic spindle checkpoint by survivin. Nature (Lond) 396:580-584.
-
F, Ambrosini G, Chu EY, Plescia J, Tognin S, Marchisio PC, and Altieri DC (1998) Control of apoptosis and mitotic spindle checkpoint by survivin. Nature (Lond) 396:580-584.
-
-
-
-
24
-
-
0000601446
-
Life and death decisions: The role of the IAPs in modulating programmed cell death
-
Liston P, Young SS, Mackenzie AE, and Korneluk RG (1997) Life and death decisions: the role of the IAPs in modulating programmed cell death. Apoptosis 2:423-441.
-
(1997)
Apoptosis
, vol.2
, pp. 423-441
-
-
Liston, P.1
Young, S.S.2
Mackenzie, A.E.3
Korneluk, R.G.4
-
25
-
-
0034789355
-
Cancer gene therapy using a survivin mutant adenovirus
-
Mesri M, Wall NR, Li J, Kim RW, and Altieri DC (2001) Cancer gene therapy using a survivin mutant adenovirus. J Clin Investig 108:981-990.
-
(2001)
J Clin Investig
, vol.108
, pp. 981-990
-
-
Mesri, M.1
Wall, N.R.2
Li, J.3
Kim, R.W.4
Altieri, D.C.5
-
26
-
-
0036892114
-
Deguelin inhibits the growth of colon cancer cells through the induction of apoptosis and cell cycle arrest
-
Murillo G, Salti GI, Kosmeder JW 2nd, Pezzuto JM, and Mehta RG (2002) Deguelin inhibits the growth of colon cancer cells through the induction of apoptosis and cell cycle arrest. Eur J Cancer 38:2446-2454.
-
(2002)
Eur J Cancer
, vol.38
, pp. 2446-2454
-
-
Murillo, G.1
Salti, G.I.2
Kosmeder, J.W.3
Pezzuto, J.M.4
Mehta, R.G.5
-
27
-
-
16444382036
-
Real-time detection of gene expression in cancer cells using molecular beacon imaging: New strategies for cancer research
-
Peng XH, Cao ZH, Xia JT, Carlson GW, Lewis MM, Wood WC, and Yang L (2005) Real-time detection of gene expression in cancer cells using molecular beacon imaging: new strategies for cancer research. Cancer Res 65:1909-1917.
-
(2005)
Cancer Res
, vol.65
, pp. 1909-1917
-
-
Peng, X.H.1
Cao, Z.H.2
Xia, J.T.3
Carlson, G.W.4
Lewis, M.M.5
Wood, W.C.6
Yang, L.7
-
28
-
-
0033026714
-
Mechanisms of apoptosis avoidance in cancer
-
Reed JC (1999) Mechanisms of apoptosis avoidance in cancer. Curr Opin Oncol 11:68-75.
-
(1999)
Curr Opin Oncol
, vol.11
, pp. 68-75
-
-
Reed, J.C.1
-
29
-
-
0034953632
-
Apoptosis-regulating proteins as targets for drug discovery
-
Reed JC (2001) Apoptosis-regulating proteins as targets for drug discovery. Trends Mol Med 7:314-319.
-
(2001)
Trends Mol Med
, vol.7
, pp. 314-319
-
-
Reed, J.C.1
-
30
-
-
18144428333
-
A survivin gene signature predicts aggressive tumor behavior
-
Salz W, Eisenberg D, Plescia J, Garlick DS, Weiss RM, Wu XR, Sun TT, and Altieri DC (2005) A survivin gene signature predicts aggressive tumor behavior. Cancer Res 65:3531-3534.
-
(2005)
Cancer Res
, vol.65
, pp. 3531-3534
-
-
Salz, W.1
Eisenberg, D.2
Plescia, J.3
Garlick, D.S.4
Weiss, R.M.5
Wu, X.R.6
Sun, T.T.7
Altieri, D.C.8
-
31
-
-
9144234685
-
Small-molecule antagonists of apoptosis suppressor XIAP exhibit broad antitumor activity
-
Schimmer AD, Welsh K, Pinilla C, Wang Z, Krajewska M, Bonneau MJ, Pedersen IM, Kitada S, Scott FL, Bailly-Maitre B, et al. (2004) Small-molecule antagonists of apoptosis suppressor XIAP exhibit broad antitumor activity. Cancer Cell 5:25-35.
-
(2004)
Cancer Cell
, vol.5
, pp. 25-35
-
-
Schimmer, A.D.1
Welsh, K.2
Pinilla, C.3
Wang, Z.4
Krajewska, M.5
Bonneau, M.J.6
Pedersen, I.M.7
Kitada, S.8
Scott, F.L.9
Bailly-Maitre, B.10
-
32
-
-
0035831473
-
Executioner caspase-3, -6, and -7 perform distinct, non-redundant roles during the demolition phase of apoptosis
-
Slee EA, Adrain C, and Martin SJ. Executioner caspase-3, -6, and -7 perform distinct, non-redundant roles during the demolition phase of apoptosis. J Biol Chem 276:7320-7326, 2001.
-
(2001)
J Biol Chem
, vol.276
, pp. 7320-7326
-
-
Slee, E.A.1
Adrain, C.2
Martin, S.J.3
-
33
-
-
0032403126
-
IAP-family protein survivin inhibits caspase activity and apoptosis induced by Fas (CD95), Bax, caspases, and anticancer drugs
-
Tamm I, Wang Y, Sausville E, Scudiero DA, Vigna N, Oltersdorf T, and Reed JC (1998) IAP-family protein survivin inhibits caspase activity and apoptosis induced by Fas (CD95), Bax, caspases, and anticancer drugs. Cancer Res 58:5315-5320.
-
(1998)
Cancer Res
, vol.58
, pp. 5315-5320
-
-
Tamm, I.1
Wang, Y.2
Sausville, E.3
Scudiero, D.A.4
Vigna, N.5
Oltersdorf, T.6
Reed, J.C.7
-
34
-
-
0033980409
-
Expression of survivin and its relationship to loss of apoptosis in breast carcinomas
-
Tanaka K, Iwamoto S, Gon G, Nohara T, Iwamoto M, and Tanigawa N (2000) Expression of survivin and its relationship to loss of apoptosis in breast carcinomas. Clin Cancer Res 6:127-134.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 127-134
-
-
Tanaka, K.1
Iwamoto, S.2
Gon, G.3
Nohara, T.4
Iwamoto, M.5
Tanigawa, N.6
-
35
-
-
0034743364
-
Pharmacokinetics of deguelin, a cancer chemopreventive agent in rats
-
Udeani GO, Zhao GM, Shin YG, Kosmeder JW 2nd, Beecher CW, Kinghorn AD, Moriarty RM, Moon RC, and Pezzuto JM (2001) Pharmacokinetics of deguelin, a cancer chemopreventive agent in rats. Cancer Chemother Pharmacol 47:263-268.
-
(2001)
Cancer Chemother Pharmacol
, vol.47
, pp. 263-268
-
-
Udeani, G.O.1
Zhao, G.M.2
Shin, Y.G.3
Kosmeder, J.W.4
Beecher, C.W.5
Kinghorn, A.D.6
Moriarty, R.M.7
Moon, R.C.8
Pezzuto, J.M.9
-
36
-
-
0142188706
-
Coexistence of high levels of apoptotic signaling and inhibitor of apoptosis proteins in human tumor cells: Implication for cancer specific therapy
-
Yang L, Cao Z, Yan H, and Wood WC (2003) Coexistence of high levels of apoptotic signaling and inhibitor of apoptosis proteins in human tumor cells: implication for cancer specific therapy. Cancer Res 63:6815-6824.
-
(2003)
Cancer Res
, vol.63
, pp. 6815-6824
-
-
Yang, L.1
Cao, Z.2
Yan, H.3
Wood, W.C.4
|